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$74+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
mar. 23 — mar. 301
dom. 3/23
dom. 3/30
1 adult, Economy
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Cheap flight deals from Detroit to Missouri

Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated marzo 18, 2025.

Round-trip from

$245
(Southwest)

One-way from

$74
(Mytrip)

Good round-trip deal

$283 or less

Good one-way deal

$160 or less
From Detroit Metropolitan Wayne County to Missouri
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One-way flight from Detroit Metropolitan Wayne County to Missouri
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Missouri.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Missouri.
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Find flight deals from Detroit to Missouri

Cheapest flights from Detroit to Missouri
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 18, 2025.

This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/1611:40 amDTW - STL
Nonstop1h 30mSouthwest
lun. 4/212:55 pmSTL - DTW
Nonstop1h 30mSouthwest
Deal found 3/18$245
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/147:55 pmDTW - STL
1 stop4h 39mDelta
lun. 4/216:50 amSTL - DTW
Nonstop1h 29mDelta
Deal found 3/17$247
This Booking.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/318:53 amDTW - STL
1 stop15h 56mFrontier
lun. 4/74:57 pmSTL - DTW
1 stop14h 03mFrontier
Deal found 3/17$250
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/245:25 amDTW - STL
1 stop6h 59mAmerican Airlines
dom. 4/275:00 amSTL - DTW
1 stop4h 38mAmerican Airlines
Deal found 3/18$251
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/25:42 pmDTW - STL
1 stop25h 10mMultiple Airlines
sáb. 4/59:50 amSTL - DTW
2 stops14h 21mMultiple Airlines
Deal found 3/17$252
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/282:53 pmDTW - STL
2 stops27h 22mSpirit Airlines
jue. 5/16:10 pmSTL - DTW
2 stops29h 54mSpirit Airlines
Deal found 3/17$253
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/159:10 amDTW - STL
1 stop4h 10mUnited Airlines
mié. 4/169:39 amSTL - DTW
2 stops8h 11mUnited Airlines
Deal found 3/18$270
This Mytrip deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/171:29 pmDTW - MCI
2 stops26h 57mMultiple Airlines
dom. 4/208:30 amMCI - DTW
1 stop25h 56mMultiple Airlines
Deal found 3/18$300
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/315:00 amDTW - MCI
1 stop12h 17mSpirit Airlines
jue. 4/36:45 pmMCI - DTW
1 stop9h 29mSpirit Airlines
Deal found 3/17$302
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/16:07 pmDTW - JLN
1 stop6h 38mUnited Airlines
sáb. 4/57:59 amJLN - DTW
1 stop4h 09mUnited Airlines
Deal found 3/17$314
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/215:30 amDTW - MCI
1 stop6h 49mAmerican Airlines
jue. 4/249:25 amMCI - DTW
1 stop5h 00mAmerican Airlines
Deal found 3/17$317
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/144:04 pmDTW - MCI
2 stops8h 40mUnited Airlines
jue. 4/177:45 amMCI - DTW
1 stop4h 17mUnited Airlines
Deal found 3/17$322

Find flights from Detroit to Missouri within your budget

Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 18, 2025.

Fly from

Detroit

Fly to

Missouri

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

mié. 4/16

11:40 am-12:10 pm

Nonstop1h 30m

Lambert-St Louis

lun. 4/21

2:55 pm-5:25 pm

Nonstop1h 30m

$245

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

lun. 4/14

7:55 pm-11:34 pm

1 stop4h 39m

Lambert-St Louis

lun. 4/21

6:50 am-9:19 am

Nonstop1h 29m

$247

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

lun. 3/31

8:53 am-11:49 pm

1 stop15h 56m

Lambert-St Louis

lun. 4/7

4:57 pm-8:00 am

1 stop14h 03m

$250

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

jue. 4/24

5:25 am-11:24 am

1 stop6h 59m

Lambert-St Louis

dom. 4/27

5:00 am-10:38 am

1 stop4h 38m

$251

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

mié. 4/2

5:42 pm-5:52 pm

1 stop25h 10m

Lambert-St Louis

sáb. 4/5

9:50 am-1:11 am

2 stops14h 21m

$252

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

lun. 4/28

2:53 pm-5:15 pm

2 stops27h 22m

Lambert-St Louis

jue. 5/1

6:10 pm-1:04 am

2 stops29h 54m

$253

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

mar. 4/15

9:10 am-12:20 pm

1 stop4h 10m

Lambert-St Louis

mié. 4/16

9:39 am-6:50 pm

2 stops8h 11m

$270

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

jue. 4/17

1:29 pm-3:26 pm

2 stops26h 57m

Kansas City

dom. 4/20

8:30 am-11:26 am

1 stop25h 56m

$300

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

lun. 3/31

5:00 am-4:17 pm

1 stop12h 17m

Kansas City

jue. 4/3

6:45 pm-5:14 am

1 stop9h 29m

$302

DetroitJoplin

DTW - JLN

DTWJLN

Detroit Metropolitan Wayne County

mar. 4/1

6:07 pm-11:45 pm

1 stop6h 38m

Joplin

sáb. 4/5

7:59 am-1:08 pm

1 stop4h 09m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 38 results
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Best time to book a flight from Detroit to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Detroit to Missouri

Get recent, data-driven insights about flights from Detroit to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Missouri?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Missouri (average of $311). Flying from Detroit Metropolitan Wayne County Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to MO?

Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 18, 2025.

When flying from Detroit Metropolitan Wayne County Airport to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to Missouri

Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated marzo 18, 2025.

The most flights from DTW to USMO are scheduled on a Monday (15 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (12 on average).

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated marzo 18, 2025.
To help decide which airline to fly from Detroit to Missouri, see what other customers have to say about Southwest, Alaska Airlines and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,280 reviews

Comfort

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Overall

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,280 reviews
Southwest
8.1
Very good
4,280 reviews

Comfort

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Overall

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Alaska Airlines
8.0
Very good
9,754 reviews
Southwest
8.1
Very good
4,280 reviews

Comfort

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Overall

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,908 reviews
Southwest
8.1
Very good
4,280 reviews

Comfort

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Overall

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,611 reviews
Southwest
8.1
Very good
4,280 reviews

Comfort

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Overall

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,280 reviews

Comfort

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Overall

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Missouri?

    For a flight from Detroit to Missouri, you will be flying from Detroit Metropolitan Wayne County. Detroit Metropolitan Wayne County (DTW) is just 17.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to Missouri one-way?

    $74 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $93 and $97, respectively.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to Missouri?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to Missouri consider Detroit Metropolitan Wayne County - Kansas City, Detroit Metropolitan Wayne County - Lambert-St Louis or Detroit Metropolitan Wayne County - Springfield-Branson as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Missouri?

    Before booking your flight to Missouri from Detroit Metropolitan Wayne County Airport, check out the most reliable airlines to get you to your destination on time: SkyWest Airlines (100%), Endeavor Airlines (100%), Aeromexico( 89%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Missouri?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to Missouri? While on average our users pay $307, our data indicates the cheapest price to be $109. The most popular route (Detroit Metropolitan Wayne County - Kansas City), is priced around $180.

  • Can I find deals for flights from Detroit to Missouri that include hotel bookings?

    Yes. In addition to deals on Detroit to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Missouri.

  • Can I find deals for business class flights from Detroit to Missouri?

    Yes. Cheapflights offers flight deals from Detroit to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Missouri (average of $311). Flying from Detroit Metropolitan Wayne County Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Detroit to Missouri

Discover the top 6 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$49Average$201FlexibilityNo cancel feeOn-time65%
FrontierCheapest$124Average$200FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$179Average$440FlexibilityNo cancel feeOn-time71%
DeltaCheapest$199Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$245Average$351FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$298Average$536FlexibilityNo cancel feeOn-time69%
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