$73+ Cheap flights from Missouri to Detroit Metropolitan Wayne County Airport (DTW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — DTW
Jun 30 — Jul 71
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Detroit with Cheapflights
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Cheapest flights from Missouri to DetroitExplore the most affordable flight options available from Missouri to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
Explore the most affordable flight options available from Missouri to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:15 pm
STL
- DTW
1 stop3h 50m
Southwest
Sat 7/47:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/30![Southwest logo]()
$167
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Sun 6/217:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Deal found 5/27![United Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:30 am
STL
- DTW
Nonstop1h 34m
Delta
Sun 6/288:50 am
DTW
- STL
Nonstop1h 42m
Delta
Deal found 5/28![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Sat 7/45:55 am
DTW
- STL
1 stop8h 35m
Southwest
Deal found 5/28![Southwest logo]()
$193
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:10 pm
STL
- DTW
1 stop6h 15m
Southwest
Fri 7/38:30 pm
DTW
- STL
1 stop3h 20m
Southwest
Deal found 5/27![Southwest logo]()
$203
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:40 pm
STL
- DTW
1 stop3h 25m
Southwest
Mon 8/176:55 am
DTW
- STL
Nonstop1h 50m
Southwest
Deal found 5/26![Southwest logo]()
$206
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Sat 6/207:10 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/27![Southwest logo]()
$209
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:33 am
STL
- DTW
Nonstop1h 32m
Delta
Sun 9/612:20 pm
DTW
- STL
1 stop12h 11m
Delta
Deal found 5/28![Delta logo]()
$211
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:05 pm
STL
- DTW
1 stop3h 49m
United Airlines
Sun 7/128:50 am
DTW
- STL
1 stop4h 21m
United Airlines
Deal found 5/28![United Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:23 am
STL
- DTW
1 stop4h 53m
United Airlines
Thu 11/125:45 am
DTW
- STL
1 stop3h 52m
United Airlines
Deal found 5/30![United Airlines logo]()
$215
This Frontier deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:19 pm
MCI
- DTW
1 stop5h 23m
Frontier
Tue 9/17:45 am
DTW
- MCI
1 stop6h 15m
Frontier
Deal found 5/29![Frontier logo]()
$258
This Priceline deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/91:45 pm
MCI
- DTW
1 stop9h 14m
Frontier
Tue 7/217:40 am
DTW
- MCI
1 stop6h 20m
Frontier
Deal found 5/28![Frontier logo]()
$263
Best flights from Missouri to DetroitDiscover carefully curated flight deals from Missouri to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
Discover carefully curated flight deals from Missouri to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:33 pm
STL
- DTW
1 stop3h 46m
United Airlines
Sat 7/1111:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Deal found 5/28![United Airlines logo]()
$177
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:30 am
STL
- DTW
Nonstop1h 34m
Delta
Wed 7/88:50 am
DTW
- STL
Nonstop1h 41m
Delta
Deal found 5/29![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:05 pm
STL
- DTW
1 stop4h 05m
Southwest
Mon 7/276:55 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/30![Southwest logo]()
$228
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:29 pm
STL
- DTW
1 stop5h 28m
United Airlines
Mon 6/297:45 pm
DTW
- STL
1 stop4h 44m
United Airlines
Deal found 5/26![United Airlines logo]()
$177
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:10 pm
STL
- DTW
Nonstop1h 35m
Delta
Mon 7/68:50 am
DTW
- STL
Nonstop1h 42m
Delta
Deal found 5/30![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:09 pm
STL
- DTW
Nonstop1h 35m
Delta
Sat 7/188:50 am
DTW
- STL
Nonstop1h 41m
Delta
Deal found 5/29![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
STL
- DTW
1 stop5h 35m
Southwest
Fri 8/143:50 pm
DTW
- STL
2 stops7h 15m
Southwest
Deal found 5/30![Southwest logo]()
$243
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Mon 7/131:25 pm
DTW
- STL
2 stops8h 35m
Southwest
Deal found 5/26![Southwest logo]()
$273
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2310:33 am
STL
- DTW
Nonstop1h 32m
Delta
Sun 9/69:00 am
DTW
- STL
Nonstop1h 37m
Delta
Deal found 5/28![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:40 am
STL
- DTW
2 stops5h 55m
Southwest
Wed 7/83:50 pm
DTW
- STL
2 stops8h 15m
Southwest
Deal found 5/29![Southwest logo]()
$274
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:57 pm
JLN
- DTW
1 stop7h 46m
United Airlines
Tue 6/168:50 am
DTW
- JLN
1 stop5h 32m
United Airlines
Deal found 5/28![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:38 am
SGF
- DTW
1 stop4h 41m
Delta
Thu 9/103:55 pm
DTW
- SGF
1 stop7h 34m
Delta
Deal found 5/26![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:25 pm
SGF
- DTW
1 stop4h 34m
United Airlines
Sun 10/259:12 pm
DTW
- SGF
1 stop4h 45m
United Airlines
Deal found 5/26![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:57 pm
JLN
- DTW
1 stop7h 46m
United Airlines
Sun 7/268:50 am
DTW
- JLN
1 stop5h 32m
United Airlines
Deal found 5/29![United Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:53 pm
SGF
- DTW
1 stop5h 06m
Delta
Mon 8/36:20 am
DTW
- SGF
1 stop5h 33m
Delta
Deal found 5/26![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:55 am
MCI
- DTW
2 stops8h 05m
Southwest
Wed 7/85:35 am
DTW
- MCI
1 stop5h 10m
Southwest
Deal found 5/29![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:07 pm
SGF
- DTW
1 stop6h 12m
United Airlines
Sun 6/147:05 am
DTW
- SGF
1 stop4h 37m
United Airlines
Deal found 5/28![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:05 am
MCI
- DTW
2 stops7h 55m
Southwest
Wed 8/52:45 pm
DTW
- MCI
2 stops8h 20m
Southwest
Deal found 5/26![Southwest logo]()
$409
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:07 pm
SGF
- DTW
1 stop6h 12m
United Airlines
Tue 6/167:47 pm
DTW
- SGF
1 stop4h 40m
United Airlines
Deal found 5/28![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:44 pm
MCI
- DTW
Nonstop2h 01m
Delta
Sat 7/42:15 pm
DTW
- MCI
Nonstop2h 04m
Delta
Deal found 5/30![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:15 pm
MCI
- DTW
1 stop5h 40m
Southwest
Sat 7/49:10 am
DTW
- MCI
2 stops8h 05m
Southwest
Deal found 5/30![Southwest logo]()
$424
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:40 am
JLN
- DTW
1 stop6h 47m
United Airlines
Wed 10/282:30 pm
DTW
- JLN
2 stops9h 49m
United Airlines
Deal found 5/29![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:13 pm
MCI
- DTW
Nonstop1h 57m
Delta
Sat 8/88:41 am
DTW
- MCI
Nonstop2h 04m
Delta
Deal found 5/30![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:07 pm
SGF
- DTW
1 stop6h 12m
United Airlines
Sat 7/411:00 am
DTW
- SGF
1 stop4h 32m
United Airlines
Deal found 5/31![United Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 pm
MCI
- DTW
Nonstop1h 57m
Delta
Sun 7/198:40 am
DTW
- MCI
Nonstop2h 04m
Delta
Deal found 5/29![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:25 am
MCI
- DTW
Nonstop1h 58m
Delta
Wed 8/57:50 pm
DTW
- MCI
Nonstop2h 00m
Delta
Deal found 5/26![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:37 pm
SGF
- DTW
1 stop4h 22m
United Airlines
Sun 9/205:25 am
DTW
- SGF
1 stop6h 23m
United Airlines
Deal found 5/29![United Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:14 am
MCI
- DTW
1 stop5h 25m
Delta
Wed 7/158:40 am
DTW
- MCI
Nonstop2h 04m
Delta
Deal found 5/27![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:22 am
SGF
- DTW
1 stop4h 35m
United Airlines
Sat 10/314:15 pm
DTW
- SGF
1 stop6h 08m
United Airlines
Deal found 5/28![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:40 pm
MCI
- DTW
1 stop4h 01m
Delta
Sun 8/1612:27 pm
DTW
- MCI
Nonstop1h 59m
Delta
Deal found 5/30![Delta logo]()
$409
Last-minute flights from Missouri to DetroitDiscover last-minute flight deals from Missouri to Detroit. Data last updated May 31, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Detroit. Data last updated May 31, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Sat 6/207:10 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/27![Southwest logo]()
$209
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Sun 6/217:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Deal found 5/27![United Airlines logo]()
$172
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Thu 7/2311:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Deal found 5/26![United Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Mon 6/2211:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Deal found 5/27![United Airlines logo]()
$232
This Expedia deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/201:45 pm
MCI
- DTW
1 stop9h 14m
Frontier
Wed 6/246:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Deal found 5/28![Frontier logo]()
$289
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Wed 7/85:34 pm
DTW
- STL
1 stop7h 25m
Frontier
Deal found 5/30![Frontier logo]()
$230
This Expedia deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:16 pm
MCI
- DTW
1 stop5h 28m
Frontier
Sat 6/276:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Deal found 5/28![Frontier logo]()
$258
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:15 pm
STL
- DTW
1 stop3h 50m
Southwest
Sat 7/47:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/30![Southwest logo]()
$167
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:30 am
STL
- DTW
Nonstop1h 34m
Delta
Fri 7/38:50 am
DTW
- STL
Nonstop1h 42m
Delta
Deal found 5/29![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Sat 7/45:55 am
DTW
- STL
1 stop8h 35m
Southwest
Deal found 5/28![Southwest logo]()
$193
This Frontier deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/271:45 pm
MCI
- DTW
1 stop9h 14m
Frontier
Sat 7/48:00 am
DTW
- MCI
1 stop6h 00m
Frontier
Deal found 5/29![Frontier logo]()
$284
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/281:25 pm
STL
- DTW
1 stop3h 15m
Southwest
Sun 7/57:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/30![Southwest logo]()
$228
One-way flights from Missouri to DetroitSearch for one-way flight options from Missouri to Detroit. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
Search for one-way flight options from Missouri to Detroit. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:20 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/28![Southwest logo]()
$73
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:40 pm
STL
- DTW
Nonstop1h 35m
Southwest
Deal found 5/28![Southwest logo]()
$79
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:45 pm
STL
- DTW
1 stop5h 45m
Southwest
Deal found 5/28![Southwest logo]()
$82
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 pm
STL
- DTW
1 stop5h 15m
United Airlines
Deal found 5/29![United Airlines logo]()
$89
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- DTW
2 stops7h 34m
United Airlines
Deal found 5/27![United Airlines logo]()
$94
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/28![Southwest logo]()
$96
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 pm
STL
- DTW
1 stop5h 15m
United Airlines
Deal found 5/29![United Airlines logo]()
$104
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/27![Southwest logo]()
$105
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:36 pm
STL
- DTW
1 stop5h 23m
United Airlines
Deal found 5/29![United Airlines logo]()
$108
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:00 am
STL
- DTW
1 stop6h 55m
Delta
Deal found 5/28![Delta logo]()
$113
This Super.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:16 pm
MCI
- DTW
1 stop5h 28m
Frontier
Deal found 5/28![Frontier logo]()
$128
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:19 pm
MCI
- DTW
1 stop5h 23m
Frontier
Deal found 5/30![Frontier logo]()
$130
Find flight deals from Missouri to Detroit
Keep the following information in mind while searching for Missouri to Detroit flight deals. Data was last updated May 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $167 (Southwest) |
One-way from | $73 (Southwest) |
Popular in | February |
Cheapest in | August |
Average price | $359 |
Good round-trip deal | $391 or less |
Good one-way deal | $193 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
Use the filters below to find and compare flights from Missouri to Detroit Metropolitan Wayne County Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Wed 7/1
5:33 pm-10:19 pm
1 stop3h 46m
Detroit Metropolitan Wayne County
Sat 7/11
11:00 am-3:46 pm
1 stop5h 46m
$177
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Wed 7/1
6:30 am-9:04 am
Nonstop1h 34m
Detroit Metropolitan Wayne County
Wed 7/8
8:50 am-9:31 am
Nonstop1h 41m
$177
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Mon 6/22
5:29 pm-11:57 pm
1 stop5h 28m
Detroit Metropolitan Wayne County
Mon 6/29
7:45 pm-11:29 pm
1 stop4h 44m
$177
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Fri 7/3
6:10 pm-8:45 pm
Nonstop1h 35m
Detroit Metropolitan Wayne County
Mon 7/6
8:50 am-9:32 am
Nonstop1h 42m
$177
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Fri 7/17
6:09 pm-8:44 pm
Nonstop1h 35m
Detroit Metropolitan Wayne County
Sat 7/18
8:50 am-9:31 am
Nonstop1h 41m
$177
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Thu 7/23
7:05 pm-12:10 am
1 stop4h 05m
Detroit Metropolitan Wayne County
Mon 7/27
6:55 am-7:30 am
Nonstop1h 35m
$228
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Sun 8/9
6:00 am-12:35 pm
1 stop5h 35m
Detroit Metropolitan Wayne County
Fri 8/14
3:50 pm-10:05 pm
2 stops7h 15m
$243
Quickest round-trip
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Sun 8/23
10:33 am-1:05 pm
Nonstop1h 32m
Detroit Metropolitan Wayne County
Sun 9/6
9:00 am-9:37 am
Nonstop1h 37m
$269
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Sat 6/13
8:45 pm-11:15 pm
Nonstop1h 30m
Detroit Metropolitan Wayne County
Mon 7/13
1:25 pm-9:00 pm
2 stops8h 35m
$273
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Wed 7/1
5:40 am-12:35 pm
2 stops5h 55m
Detroit Metropolitan Wayne County
Wed 7/8
3:50 pm-11:05 pm
2 stops8h 15m
$274
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Missouri to Detroit
Have a flexible travel schedule? Discover the best time to fly to Detroit from Missouri with our price prediction graph.
STL-DTW
MCI-DTW
JLN-DTW
SGF-DTW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Detroit Metropolitan Wayne County Airport
USMO-DTW
STL-DTW
MCI-DTW
JLN-DTW
SGF-DTW
What is the cheapest month to book a flight from Missouri to Detroit Metropolitan Wayne County Airport?
Currently, August is the cheapest month in which you can book a flight from Missouri to Detroit Metropolitan Wayne County Airport (average of $27). Flying from Missouri to Detroit Metropolitan Wayne County Airport in December is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to DTW?
Find hourly flight availability from Missouri to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 31, 2026.
It’s optimal to fly from Missouri to Detroit Metropolitan Wayne County Airport in the evening. By choosing this option you can save up to 72% on the cost of your flight, compared to a flight at noon.
Weekly flight availability from Missouri to Detroit Metropolitan Wayne County Airport
Explore weekly flight availability from Missouri to Detroit. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 31, 2026.
The most flights from USMO to DTW are scheduled on a Monday (16 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (11 on average).
How much does it cost to fly round-trip from Missouri to Detroit Metropolitan Wayne County Airport?
How far ahead should I book a flight from Missouri to Detroit Metropolitan Wayne County Airport?
The best time to book flights from Missouri to Detroit Metropolitan Wayne County Airport is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Missouri to Detroit Metropolitan Wayne County Airport?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Detroit. Price data was last updated on May 23, 2026.
Travelers seeking maximum savings on their Missouri to Detroit Metropolitan Wayne County Airport flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Detroit Metropolitan Wayne County Airport?
Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locationsSterling Heights
Dearborn
Troy
Southfield
Warren
Auburn Hills
Pontiac
Southgate
Allen Park
Romulus
Rochester Hills
Roseville
Livonia
Monroe
Utica
Ypsilanti
Plymouth
Fremont
Port Huron
Madison Heights
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Detroit
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Detroit by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Detroit
Explore flights to Detroit departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 31, 2026.
Search flights from Missouri to Detroit by cabin class
Find flights from Missouri to Detroit, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Detroit flights
Browse other Missouri and Detroit flight options. Last updated on May 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Detroit flights
Consider these flights traveling from Missouri to Detroit.
Top 6 airlines flying from Missouri to Detroit
Discover the top 6 airlines that operate flights from Missouri to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$38 | Average$156 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$69 | Average$403 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$80 | Average$231 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$119 | Average$394 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$269 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$309 | Average$428 | FlexibilityNo cancel fee | On-time69% |