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Missouri

$73+ Cheap flights from Charleston (CHS) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Charleston to Missouri

Cheapest flights from Charleston to Missouri
Explore the most affordable flight options available from Charleston to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:18 pmCHS - MCI
1 stop19h 52mSpirit Airlines
Sun 1/46:15 pmMCI - CHS
1 stop26h 08mSpirit Airlines
Deal found 12/10$273
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:18 pmCHS - MCI
1 stop19h 52mSpirit Airlines
Thu 1/16:15 pmMCI - CHS
1 stop26h 08mSpirit Airlines
Deal found 12/10$295
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:09 pmCHS - MCI
1 stop12h 30mMultiple Airlines
Sun 12/286:15 pmMCI - CHS
1 stop26h 08mMultiple Airlines
Deal found 12/10$361
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:18 pmCHS - MCI
1 stop19h 52mSpirit Airlines
Wed 12/316:15 pmMCI - CHS
1 stop26h 08mSpirit Airlines
Deal found 12/11$363
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:18 pmCHS - MCI
2 stops25h 41mMultiple Airlines
Wed 12/313:47 pmMCI - CHS
1 stop15h 50mMultiple Airlines
Deal found 12/11$364
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:10 amCHS - STL
1 stop4h 25mAmerican Airlines
Tue 1/63:40 pmSTL - CHS
1 stop5h 54mAmerican Airlines
Deal found 12/11$378
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:59 pmCHS - STL
1 stop8h 34mMultiple Airlines
Tue 1/65:11 pmSTL - CHS
2 stops45h 59mMultiple Airlines
Deal found 12/11$382
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:49 pmCHS - MCI
1 stop21h 07mSpirit Airlines
Thu 12/186:15 pmMCI - CHS
1 stop26h 08mSpirit Airlines
Deal found 12/9$396
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:10 pmCHS - SGF
1 stop5h 46mAmerican Airlines
Tue 12/307:06 amSGF - CHS
1 stop6h 42mAmerican Airlines
Deal found 12/11$402
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:59 pmCHS - STL
1 stop8h 34mMultiple Airlines
Sun 12/2810:57 amSTL - CHS
2 stops33h 26mMultiple Airlines
Deal found 12/10$405
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:33 pmCHS - MCI
2 stops26h 37mMultiple Airlines
Thu 1/16:15 pmMCI - CHS
1 stop26h 08mMultiple Airlines
Deal found 12/10$417
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:20 pmCHS - MCI
1 stop5h 50mSouthwest
Wed 12/316:00 amMCI - CHS
1 stop10h 05mSouthwest
Deal found 12/11$427

Find flight deals from Charleston to Missouri

Keep the following information in mind while searching for Charleston to Missouri flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$208
(Kiwi.com)

One-way from

$73
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$384
Provider with most accurate pricing for Charleston-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Lambert-St Louis flights.
Search Deals
From Charleston to Missouri
Search Deals
One-way flight from Charleston to Missouri
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Charleston to Missouri that are best for you.

Fly from

Charleston

Fly to

Missouri

Route

Depart

Return

Price

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 1/22

3:01 pm-10:23 am

1 stop20h 22m

Lambert-St Louis

Sun 1/25

5:42 pm-5:36 pm

2 stops22h 54m

$208

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/17

6:35 pm-9:11 am

2 stops15h 36m

Lambert-St Louis

Mon 1/19

5:11 pm-8:38 am

1 stop14h 27m

$249

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 1/16

6:05 am-10:34 pm

2 stops17h 29m

Lambert-St Louis

Mon 1/19

5:11 pm-8:38 am

1 stop14h 27m

$293

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Thu 1/8

6:05 am-10:42 am

1 stop5h 37m

Columbia Regional

Mon 1/12

8:09 am-2:02 pm

1 stop4h 53m

$308

CharlestonKansas City

CHS - MCI

CHSMCI

Charleston

Thu 12/18

10:18 pm-10:59 pm

2 stops25h 41m

Kansas City

Sun 1/4

6:15 pm-9:23 pm

1 stop26h 08m

$315

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 1/13

6:30 am-11:05 am

1 stop5h 35m

Lambert-St Louis

Sat 1/17

5:00 pm-11:55 pm

1 stop5h 55m

$325

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/17

2:58 pm-7:27 pm

1 stop5h 29m

Lambert-St Louis

Mon 1/19

12:44 pm-7:04 pm

1 stop5h 20m

$337

CharlestonKansas City

CHS - MCI

CHSMCI

Charleston

Tue 2/24

3:45 pm-10:51 pm

1 stop8h 06m

Kansas City

Thu 2/26

6:33 pm-11:59 pm

1 stop4h 26m

$345

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/17

6:45 am-1:50 pm

2 stops8h 05m

Lambert-St Louis

Mon 1/19

8:10 am-9:40 pm

2 stops12h 30m

$353

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 2/13

5:27 am-9:06 am

1 stop4h 39m

Lambert-St Louis

Tue 2/17

1:10 pm-8:45 pm

1 stop6h 35m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 48 results
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Best time to book a flight from Charleston to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Missouri

What is the cheapest month to book a flight from Charleston to Missouri?

Currently, June is the cheapest month in which you can book a flight from Charleston to Missouri (average of $128). Flying from Charleston to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to MO?

Find hourly flight availability from Charleston to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Charleston to Missouri is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 14% on airfare.

What is the cheapest day to fly from Charleston to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Charleston to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charleston to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Charleston to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Charleston to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Missouri?

    If you book a flight to Missouri from Charleston, you will be flying from Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How popular is this Charleston to Missouri flight route?

    The Charleston to Missouri flight path was viewed by 9 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Charleston to Missouri?

    There are many flights that can get you from Charleston to Missouri in 5h 35m. Fly via United Airlines, Spirit Airlines, or Delta to get the fastest option. The distance from Charleston to Missouri is about 705 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Charleston to Missouri?

    When deciding which route to take from Charleston to Missouri consider Charleston - Lambert-St Louis, Charleston - Kansas City or Charleston - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Charleston to Missouri that include hotel bookings?

    Yes. In addition to deals on Charleston to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Missouri.

  • Can I find deals for business class flights from Charleston to Missouri?

    Yes. Cheapflights offers flight deals from Charleston to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Missouri?

    Currently, June is the cheapest month in which you can book a flight from Charleston to Missouri (average of $128). Flying from Charleston to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to Missouri

Discover the top 3 airlines that operate flights from Charleston to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$226Average$430FlexibilityNo cancel feeOn-time63%
DeltaCheapest$242Average$373FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$397FlexibilityNo cancel feeOn-time71%

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