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$368+ Cheap flights from Odessa, TX to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/29. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — MEX
Apr 20 — Apr 271
Mon 4/20
Mon 4/27
1 adult, Economy
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Cheap flight deals from Odessa to Mexico

Cheapest flights from Odessa to Mexico
Explore the most affordable flight options available from Odessa to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 21, 2026.

This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:26 pm
MAF
-
CUN
1 stop15h 31m
American Airlines
Thu 4/308:00 am
CUN
-
MAF
1 stop9h 46m
American Airlines
Deal found 3/16$441
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:26 pm
MAF
-
CUN
1 stop13h 34m
American Airlines
Tue 4/284:10 pm
CUN
-
MAF
1 stop7h 36m
American Airlines
Deal found 3/20$490
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:15 am
MAF
-
CUN
1 stop7h 45m
American Airlines
Tue 4/214:10 pm
CUN
-
MAF
1 stop7h 36m
American Airlines
Deal found 3/20$506
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:26 pm
MAF
-
CUN
1 stop15h 30m
American Airlines
Thu 5/74:10 pm
CUN
-
MAF
1 stop7h 36m
American Airlines
Deal found 3/16$509
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:26 pm
MAF
-
CUN
1 stop15h 31m
American Airlines
Sat 5/93:01 pm
CUN
-
MAF
1 stop9h 05m
American Airlines
Deal found 3/18$532
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:26 pm
MAF
-
SJD
1 stop15h 09m
American Airlines
Tue 4/212:59 pm
SJD
-
MAF
1 stop15h 46m
American Airlines
Deal found 3/16$537
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:24 pm
MAF
-
SJD
1 stop15h 11m
American Airlines
Mon 5/188:40 am
SJD
-
MAF
1 stop13h 06m
American Airlines
Deal found 3/16$582
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:00 am
MAF
-
SJD
1 stop10h 59m
American Airlines
Sun 5/108:40 am
SJD
-
MAF
1 stop13h 06m
American Airlines
Deal found 3/19$598
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:00 am
MAF
-
SJD
1 stop7h 30m
United Airlines
Thu 5/71:44 pm
SJD
-
MAF
1 stop6h 02m
United Airlines
Deal found 3/16$602
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:26 pm
MAF
-
SJD
1 stop16h 05m
American Airlines
Tue 4/1411:53 am
SJD
-
MAF
1 stop9h 53m
American Airlines
Deal found 3/20$644
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:45 am
MAF
-
SJD
2 stops25h 05m
United Airlines
Tue 4/211:02 pm
SJD
-
MAF
2 stops20h 02m
United Airlines
Deal found 3/17$652
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:58 am
MAF
-
SJD
1 stop7h 45m
United Airlines
Thu 6/1811:32 am
SJD
-
MAF
1 stop10h 12m
United Airlines
Deal found 3/16$654

Find flight deals from Odessa to Mexico

Keep the following information in mind while searching for Odessa to Mexico flight deals. Data was last updated March 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$441
(American Airlines)

One-way from

$368
(American Airlines)

Popular in

August

Cheapest in

November

Average price

$658
Provider with most accurate pricing for Midland Intl-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Midland Intl-Mexico City Benito Juarez flights.
Search Deals
From Odessa to Mexico
Search Deals
One-way flight from Odessa to Mexico
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Odessa to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

Mon 4/27

8:26 pm-11:57 am

1 stop15h 31m

Cancun

Thu 4/30

8:00 am-5:46 pm

1 stop9h 46m

$441

MidlandSan José del Cabo

MAF - SJD

MAFSJD

Midland Intl

Fri 4/17

6:48 am-12:46 pm

1 stop7h 58m

San José del Cabo Los Cabos

Tue 4/21

2:59 pm-8:45 am

1 stop15h 46m

$537

MidlandSan José del Cabo

MAF - SJD

MAFSJD

Midland Intl

Sat 5/2

8:26 pm-9:35 am

1 stop15h 09m

San José del Cabo Los Cabos

Sat 5/16

1:46 pm-12:06 am

1 stop8h 20m

$537

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

Tue 4/28

5:00 am-2:18 pm

1 stop9h 18m

Cancun

Wed 4/29

2:49 pm-9:39 pm

1 stop6h 50m

$551

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

Mon 4/27

5:00 am-12:33 pm

1 stop7h 33m

Cancun

Thu 4/30

7:51 am-10:15 pm

2 stops14h 24m

$556

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

Thu 5/7

6:48 am-2:57 pm

1 stop8h 09m

Cancun

Mon 5/11

4:10 pm-11:46 pm

1 stop7h 36m

$577

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

Mon 5/11

7:00 am-7:19 pm

1 stop12h 19m

Cancun

Wed 5/13

2:49 pm-9:46 pm

1 stop6h 57m

$597

MidlandSan José del Cabo

MAF - SJD

MAFSJD

Midland Intl

Mon 5/18

7:00 am-10:30 am

1 stop5h 30m

San José del Cabo Los Cabos

Wed 5/20

1:17 pm-10:15 pm

1 stop6h 58m

$602

MidlandSan José del Cabo

MAF - SJD

MAFSJD

Midland Intl

Mon 5/4

5:00 am-10:30 am

1 stop7h 30m

San José del Cabo Los Cabos

Thu 5/7

1:44 pm-9:46 pm

1 stop6h 02m

$602

MidlandCozumel

MAF - CZM

MAFCZM

Midland Intl

Mon 4/27

5:00 am-2:42 pm

1 stop10h 42m

Cozumel

Thu 4/30

3:52 pm-11:15 pm

1 stop6h 23m

$691

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from Odessa to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Mexico

What is the cheapest month to book a flight from Odessa to Mexico?

Currently, December is the cheapest month in which you can book a flight from Odessa to Mexico (average of $270). Flying from Odessa to Mexico in March is currently the most expensive (average of $575). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated March 21, 2026.
See what other customers who have flown with United Airlines and American Airlines from Odessa to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,452 reviews

Crew

8.1

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,452 reviews
United Airlines
7.4
Good
9,452 reviews

Crew

8.1

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,488 reviews
United Airlines
7.4
Good
9,452 reviews

Crew

8.1

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Odessa to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Mexico?

    For as low as $551, American Airlines can have you in Mexico from Odessa in 9h 18m. Airlines will cover a distance of 1208 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Odessa to Mexico?

    While some choose either Midland Intl - Cozumel or Midland Intl - San José del Cabo Los Cabos, Midland Intl - Cancun is the most popular route from Odessa to Mexico.

  • Can I find deals for flights from Odessa to Mexico that include hotel bookings?

    Yes. In addition to deals on Odessa to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Mexico.

  • Can I find deals for business class flights from Odessa to Mexico?

    Yes. Cheapflights offers flight deals from Odessa to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to Mexico?

    Currently, December is the cheapest month in which you can book a flight from Odessa to Mexico (average of $270). Flying from Odessa to Mexico in March is currently the most expensive (average of $575). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Odessa to Mexico

Discover the top 2 airlines that operate flights from Odessa to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$344Average$609FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$441Average$665FlexibilityNo cancel feeOn-time69%

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