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$421+ Cheap flights from Odessa, TX to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — MEX
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Odessa to Mexico

Keep the following information in mind while searching for Odessa to Mexico flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$421
(American Airlines)

Popular in

August

Cheapest in

July

Average price

$802
From Odessa to Mexico
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Odessa to Mexico

Cheapest flights from Odessa to Mexico
Explore the most affordable flight options available from Odessa to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:00 amMAF - CUN
1 stop5h 56mAmerican Airlines
sáb. 10/412:00 pmCUN - MAF
1 stop10h 12mAmerican Airlines
Deal found 9/15$421
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:30 amMAF - CUN
2 stops14h 45mDelta
sáb. 10/412:40 pmCUN - MAF
2 stops23h 13mDelta
Deal found 9/15$425
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/112:06 pmMAF - CUN
1 stop7h 14mUnited Airlines
vie. 10/33:01 pmCUN - MAF
1 stop7h 12mUnited Airlines
Deal found 9/14$442
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/206:00 amMAF - CUN
1 stop7h 50mAmerican Airlines
vie. 10/244:00 pmCUN - MAF
1 stop6h 34mAmerican Airlines
Deal found 9/14$444
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/212:03 pmMAF - CUN
1 stop7h 15mUnited Airlines
mar. 12/95:55 pmCUN - MAF
1 stop6h 18mUnited Airlines
Deal found 9/14$448
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/29:00 amMAF - CUN
1 stop7h 00mSouthwest
mar. 12/98:20 amCUN - MAF
2 stops8h 25mSouthwest
Deal found 9/14$452
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/74:31 pmMAF - CUN
1 stop17h 32mAmerican Airlines
mié. 11/128:45 amCUN - MAF
1 stop12h 41mAmerican Airlines
Deal found 9/15$496
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/17:00 amMAF - CUN
2 stops9h 00mSouthwest
vie. 10/32:10 pmCUN - MAF
2 stops9h 40mSouthwest
Deal found 9/14$505
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/209:46 amMAF - CUN
1 stop4h 51mUnited Airlines
vie. 10/247:51 amCUN - MAF
2 stops14h 07mUnited Airlines
Deal found 9/14$536
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/710:45 amMAF - CUN
1 stop6h 10mSouthwest
mié. 11/128:20 amCUN - MAF
2 stops8h 25mSouthwest
Deal found 9/15$541
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/258:28 pmMAF - CUN
1 stop13h 29mAmerican Airlines
mar. 9/307:50 amCUN - MAF
1 stop15h 14mAmerican Airlines
Deal found 9/15$561
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/27:05 pmMAF - CZM
1 stop18h 18mUnited Airlines
mar. 12/92:25 pmCZM - MAF
2 stops26h 01mUnited Airlines
Deal found 9/14$582

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Odessa to Mexico that are best for you.

Fly from

Odessa

Fly to

Mexico

Route

Depart

Return

Price

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

mar. 9/30

5:00 am-10:56 am

1 stop5h 56m

Cancun

sáb. 10/4

12:00 pm-10:12 pm

1 stop10h 12m

$421

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

mar. 9/30

5:30 am-8:15 pm

2 stops14h 45m

Cancun

sáb. 10/4

12:40 pm-11:53 am

2 stops23h 13m

$425

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

mié. 10/1

12:06 pm-7:20 pm

1 stop7h 14m

Cancun

vie. 10/3

3:01 pm-10:13 pm

1 stop7h 12m

$442

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

lun. 10/20

6:00 am-1:50 pm

1 stop7h 50m

Cancun

vie. 10/24

4:00 pm-10:34 pm

1 stop6h 34m

$444

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

mar. 12/2

12:03 pm-8:18 pm

1 stop7h 15m

Cancun

mar. 12/9

5:55 pm-11:13 pm

1 stop6h 18m

$448

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

mar. 12/2

9:00 am-5:00 pm

1 stop7h 00m

Cancun

mar. 12/9

8:20 am-3:45 pm

2 stops8h 25m

$452

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

vie. 11/7

4:31 pm-11:03 am

1 stop17h 32m

Cancun

mié. 11/12

8:45 am-8:26 pm

1 stop12h 41m

$496

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

mié. 10/1

7:00 am-4:00 pm

2 stops9h 00m

Cancun

vie. 10/3

2:10 pm-11:50 pm

2 stops9h 40m

$505

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

lun. 10/20

9:46 am-2:37 pm

1 stop4h 51m

Cancun

vie. 10/24

7:51 am-9:58 pm

2 stops14h 07m

$536

MidlandCancún

MAF - CUN

MAFCUN

Midland Intl

vie. 11/7

10:45 am-5:55 pm

1 stop6h 10m

Cancun

mié. 11/12

8:20 am-3:45 pm

2 stops8h 25m

$541

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 16 results
1
2

Best time to book a flight from Odessa to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Mexico

What is the cheapest month to book a flight from Odessa to Mexico?

Currently, May is the cheapest month in which you can book a flight from Odessa to Mexico (average of $387). Flying from Odessa to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OD3 to MX?

Find hourly flight availability from Odessa to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to Mexico as you normally would.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated septiembre 15, 2025.
See what other customers who have flown with Southwest, United Airlines, and American Airlines from Odessa to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Odessa to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Mexico?

    For as low as $421, American Airlines can have you in Mexico from Odessa in 5h 56m. Airlines will cover a distance of 1208 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Odessa to Mexico?

    While some choose either Midland Intl - Cozumel or Midland Intl - San José del Cabo Los Cabos, Midland Intl - Cancun is the most popular route from Odessa to Mexico.

  • Can I find deals for flights from Odessa to Mexico that include hotel bookings?

    Yes. In addition to deals on Odessa to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Mexico.

  • Can I find deals for business class flights from Odessa to Mexico?

    Yes. Cheapflights offers flight deals from Odessa to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Odessa to Mexico (average of $387). Flying from Odessa to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Odessa to Mexico

Discover the top 3 airlines that operate flights from Odessa to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$344Average$624FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$453Average$799FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$563Average$784FlexibilityNo cancel feeOn-time63%

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