$126+ Cheap flights from Knoxville (TYS) to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to MexicoExplore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:05 am -
2 stops12h 40m
Tue 12/1512:35 pm -
1 stop8h 10m
Deal found 9/13![Southwest logo]()
$429
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:55 am -
1 stop9h 05m
Sat 12/1211:45 am -
1 stop8h 00m
Deal found 9/14![Southwest logo]()
$451
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:37 pm -
1 stop22h 29m
Mon 10/197:49 pm -
2 stops20h 25m
Deal found 9/15![Multiple Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:55 am -
1 stop9h 05m
Mon 12/2111:20 am -
2 stops11h 15m
Deal found 9/15![Southwest logo]()
$484
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:14 pm -
2 stops26h 39m
Sat 10/2410:47 pm -
1 stop8h 57m
Deal found 9/15![Multiple Airlines logo]()
$493
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:05 am -
2 stops12h 40m
Mon 12/148:20 am -
2 stops11h 25m
Deal found 9/16![Southwest logo]()
$503
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:00 am -
1 stop15h 37m
Mon 12/710:27 am -
1 stop8h 58m
Deal found 9/13![Multiple Airlines logo]()
$525
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:01 pm -
2 stops29h 09m
Wed 11/2512:26 pm -
1 stop10h 28m
Deal found 9/15![Multiple Airlines logo]()
$540
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 am -
2 stops24h 35m
Fri 11/611:00 am -
1 stop10h 35m
Deal found 9/15![Multiple Airlines logo]()
$541
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:40 am -
2 stops7h 20m
Wed 11/412:35 pm -
1 stop8h 15m
Deal found 9/15![Southwest logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:00 am -
1 stop15h 37m
Mon 12/143:35 pm -
2 stops43h 00m
Deal found 9/13![Multiple Airlines logo]()
$558
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 am -
1 stop12h 30m
Sun 9/2711:05 am -
1 stop27h 38m
Deal found 9/16![Multiple Airlines logo]()
$563
Best flights from Knoxville to MexicoDiscover carefully curated flight deals from Knoxville to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Knoxville to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:05 am -
2 stops12h 40m
Tue 12/1512:35 pm -
1 stop8h 10m
Deal found 9/13![Southwest logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:37 pm -
1 stop22h 29m
Mon 10/197:49 pm -
2 stops20h 25m
Deal found 9/15![Multiple Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:45 am -
1 stop6h 20m
Tue 10/2011:14 am -
1 stop11h 45m
Deal found 9/12![United Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:47 am -
1 stop7h 43m
Thu 1/213:10 pm -
1 stop5h 30m
Deal found 9/15![Delta logo]()
$570
This Aeromexico deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:40 pm -
2 stops10h 00m
Mon 12/72:12 pm -
1 stop6h 44m
Deal found 9/13![Aeromexico logo]()
$639
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/95:30 am -
1 stop7h 00m
Tue 2/231:56 pm -
1 stop9h 03m
Deal found 9/15![American Airlines logo]()
$655
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:55 am -
1 stop9h 05m
Sat 12/1211:45 am -
1 stop8h 00m
Deal found 9/14![Southwest logo]()
$451
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:14 pm -
2 stops26h 39m
Sat 10/2410:47 pm -
1 stop8h 57m
Deal found 9/15![Multiple Airlines logo]()
$493
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/238:00 am -
1 stop11h 45m
Thu 1/2812:10 pm -
1 stop7h 35m
Deal found 9/12![Southwest logo]()
$482
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:45 am -
1 stop7h 10m
Wed 11/412:28 pm -
1 stop9h 29m
Deal found 9/12![United Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1310:05 am -
1 stop5h 15m
Wed 1/2011:18 am -
2 stops12h 28m
Deal found 9/15![Delta logo]()
$570
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:05 am -
2 stops12h 40m
Mon 12/148:20 am -
2 stops11h 25m
Deal found 9/16![Southwest logo]()
$503
This Aeromexico deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:00 pm -
2 stops9h 25m
Mon 12/149:16 am -
2 stops9h 58m
Deal found 9/14![Aeromexico logo]()
$639
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:49 pm -
1 stop10h 21m
Fri 11/611:00 am -
1 stop10h 35m
Deal found 9/15![Multiple Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:01 am -
2 stops10h 54m
Tue 11/104:55 pm -
2 stops17h 06m
Deal found 9/15![American Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:06 pm -
1 stop11h 44m
Mon 10/197:05 am -
1 stop11h 03m
Deal found 9/14![Delta logo]()
$637
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am -
2 stops8h 35m
Wed 11/412:35 pm -
1 stop8h 15m
Deal found 9/12![Southwest logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:00 am -
1 stop14h 45m
Mon 10/196:20 am -
2 stops33h 54m
Deal found 9/14![Multiple Airlines logo]()
$604
This Aeromexico deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:40 am -
1 stop7h 30m
Tue 10/2012:20 pm -
1 stop8h 02m
Deal found 9/14![Aeromexico logo]()
$670
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:04 pm -
2 stops16h 47m
Mon 12/76:00 am -
2 stops11h 46m
Deal found 9/13![American Airlines logo]()
$699
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:15 am -
1 stop5h 30m
Tue 3/239:05 am -
1 stop6h 32m
Deal found 9/16![United Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:00 am -
2 stops15h 45m
Thu 12/179:50 am -
2 stops13h 07m
Deal found 9/13![Delta logo]()
$641
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:20 am -
1 stop7h 40m
Fri 11/611:20 am -
1 stop10h 25m
Deal found 9/15![Southwest logo]()
$579
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:25 pm -
1 stop17h 05m
Tue 1/57:15 pm -
1 stop17h 48m
Deal found 9/15![American Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:40 pm -
2 stops22h 02m
Wed 11/114:50 pm -
2 stops17h 03m
Deal found 9/16![United Airlines logo]()
$707
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/95:30 am -
2 stops13h 51m
Tue 2/234:00 pm -
2 stops16h 12m
Deal found 9/14![Delta logo]()
$649
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:45 am -
2 stops33h 34m
Thu 11/59:46 am -
1 stop26h 03m
Deal found 9/14![Multiple Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:25 pm -
2 stops20h 17m
Wed 10/213:52 pm -
2 stops16h 53m
Deal found 9/16![United Airlines logo]()
$707
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/134:00 pm -
1 stop5h 50m
Wed 1/272:10 pm -
1 stop8h 36m
Deal found 9/12![Delta logo]()
$657
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
2 stops11h 22m
Thu 11/51:44 pm -
1 stop8h 03m
Deal found 9/14![American Airlines logo]()
$732
Last-minute flights from Knoxville to MexicoDiscover last-minute flight deals from Knoxville to Mexico. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mexico. Data last updated September 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 am -
1 stop12h 30m
Sun 9/2711:05 am -
1 stop27h 38m
Deal found 9/16![Multiple Airlines logo]()
$563
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:37 pm -
1 stop22h 29m
Mon 10/197:49 pm -
2 stops20h 25m
Deal found 9/15![Multiple Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop15h 45m
Tue 10/137:00 am -
2 stops25h 05m
Deal found 9/16![Multiple Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:45 am -
1 stop6h 20m
Tue 10/207:51 am -
2 stops11h 58m
Deal found 9/12![United Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop9h 13m
Wed 10/212:15 pm -
1 stop8h 03m
Deal found 9/14![American Airlines logo]()
$587
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:14 pm -
2 stops26h 39m
Sat 10/2410:47 pm -
1 stop8h 57m
Deal found 9/15![Multiple Airlines logo]()
$493
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am -
2 stops8h 35m
Wed 11/48:20 am -
2 stops11h 30m
Deal found 9/12![Southwest logo]()
$549
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:45 am -
1 stop7h 10m
Wed 11/412:28 pm -
1 stop9h 29m
Deal found 9/12![United Airlines logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 am -
2 stops24h 35m
Fri 11/611:00 am -
1 stop10h 35m
Deal found 9/15![Multiple Airlines logo]()
$541
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:20 am -
1 stop7h 40m
Fri 11/611:20 am -
1 stop10h 25m
Deal found 9/15![Southwest logo]()
$579
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:40 am -
2 stops7h 20m
Wed 11/48:20 am -
2 stops11h 30m
Deal found 9/15![Southwest logo]()
$544
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:26 pm -
1 stop18h 32m
Wed 11/47:00 am -
1 stop7h 05m
Deal found 9/15![American Airlines logo]()
$581
One-way flights from Knoxville to MexicoSearch for one-way flight options from Knoxville to Mexico. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Knoxville to Mexico. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:08 pm -
2 stops23h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:41 pm -
2 stops24h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:03 pm -
1 stop25h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$187
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/316:50 am -
2 stops12h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:04 am -
3 stops55h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:41 pm -
2 stops21h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:41 pm -
2 stops51h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:52 pm -
3 stops41h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/289:45 am -
3 stops32h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:14 pm -
2 stops42h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:00 am -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$303
This Aeromexico deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/317:07 am -
1 stop6h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Aeromexico logo]()
$316
Find flight deals from Knoxville to Mexico
Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $429 (Southwest) |
One-way from | $126 (Kiwi.com) |
Popular in | September |
Cheapest in | November |
Average price | $1,064 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Thu 11/12
7:45 am-11:06 am
1 stop28h 21m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Sat 10/24
4:41 pm-3:27 pm
2 stops24h 46m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$186
KnoxvilleMexico City
TYS Knoxville McGhee Tyson - MEX Mexico City Benito Juarez
TYSMEX
Knoxville McGhee Tyson
Fri 10/16
10:03 pm-9:45 pm
1 stop25h 42m
Mexico City Benito Juarez
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$187
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Sun 1/31
6:50 am-7:45 pm
2 stops12h 55m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$229
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Sun 11/22
11:04 am-6:07 pm
3 stops55h 03m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$254
KnoxvilleSan José del Cabo
TYS Knoxville McGhee Tyson - SJD San José del Cabo Los Cabos
TYSSJD
Knoxville McGhee Tyson
Wed 10/7
6:41 pm-7:04 pm
2 stops51h 23m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$270
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Thu 1/28
9:45 am-6:07 pm
3 stops32h 22m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$280
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Wed 10/14
4:14 pm-9:58 am
2 stops42h 44m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$302
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Thu 1/28
8:00 am-3:15 pm
1 stop7h 15m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$303
KnoxvilleCozumel
TYS Knoxville McGhee Tyson - CZM Cozumel Intl
TYSCZM
Knoxville McGhee Tyson
Sun 1/31
7:07 am-1:50 pm
1 stop6h 43m
Cozumel Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$316
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
TYS-GDL
TYS-MEX
TYS-CUN
TYS-SJD
TYS-MTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mexico
TYS-MX0
TYS-GDL
TYS-MEX
TYS-CUN
TYS-SJD
What is the cheapest month to book a flight from Knoxville to Mexico?
Currently, April is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $620). Flying from Knoxville to Mexico in December is currently the most expensive (average of $1,050). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Knoxville to Mexico?
To ensure you get the cheapest price possible for a flight from Knoxville to Mexico, you should look to book at least 17 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated September 17, 2026.
Read through reviews of airlines operating flights from Knoxville to Mexico, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Mexico
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Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Mexico by cabin class
Find flights from Knoxville to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Mexico flights
Browse other Knoxville and Mexico flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Mexico flights
Consider these flights traveling from Knoxville to Mexico.
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Consider these flights traveling to Mexico regions.
Top 5 airlines flying from Knoxville to Mexico
Discover the top 5 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$318 | Average$690 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$382 | Average$742 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$473 | Average$810 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$485 | Average$623 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$511 | Average$647 | FlexibilityNo cancel fee | On-timeN/A |