Mexico

$185+ Cheap flights from Knoxville (TYS) to Mexico

TYS — MEX
Dec 3 — Dec 101
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Cheap flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico

Sat 11/146:23 pm -
2 stops19h 18m
Wed 11/2512:26 pm -
1 stop10h 28m
Deal found 10/29$507
Mon 11/161:38 pm -
2 stops20h 56m
Wed 11/2512:26 pm -
1 stop10h 28m
Deal found 10/29$516
Wed 12/309:22 pm -
2 stops26h 33m
Thu 1/711:10 am -
1 stop25h 21m
Deal found 11/1$519
Sun 11/157:30 am -
2 stops30h 11m
Wed 11/2512:26 pm -
1 stop10h 28m
Deal found 10/29$520
Fri 11/138:35 am -
2 stops29h 06m
Wed 11/2512:26 pm -
1 stop10h 28m
Deal found 10/29$542
Mon 11/237:11 pm -
1 stop23h 58m
Mon 12/76:15 am -
2 stops29h 52m
Deal found 10/30$553
Tue 12/296:00 am -
1 stop14h 45m
Thu 1/711:10 am -
1 stop25h 21m
Deal found 11/1$555
Thu 12/317:30 am -
2 stops40h 15m
Thu 1/711:10 am -
1 stop25h 21m
Deal found 11/1$560
Thu 11/128:33 pm -
2 stops17h 08m
Wed 11/2512:26 pm -
1 stop10h 28m
Deal found 10/29$563
Wed 12/3012:06 pm -
1 stop11h 49m
Fri 1/85:55 am -
2 stops28h 15m
Deal found 11/1$574
Sun 12/138:10 am -
1 stop9h 45m
Sun 12/2012:30 pm -
2 stops10h 10m
Deal found 10/29$590
Fri 12/119:49 pm -
1 stop19h 26m
Sat 1/164:47 pm -
2 stops21h 10m
Deal found 11/2$595

Find flight deals from Knoxville to Mexico

Round-trip from

$343
(Kiwi.com)

One-way from

$185
(Kiwi.com)
From Knoxville McGhee Tyson to Mexico
One-way flight from Knoxville McGhee Tyson to Mexico

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.

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Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Mon 12/14

7:55 am-5:00 pm

1 stop9h 05m

Cancun

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$229

KnoxvilleGuadalajara

TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal

TYSGDL

Knoxville McGhee Tyson

Fri 11/13

8:25 am-8:38 pm

2 stops13h 13m

Guadalajara Miguel Hidal

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$245

KnoxvilleGuadalajara

TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal

TYSGDL

Knoxville McGhee Tyson

Thu 11/12

7:45 am-11:06 am

1 stop28h 21m

Guadalajara Miguel Hidal

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$268

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Mon 12/14

9:00 am-10:28 am

2 stops25h 28m

Cancun

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$271

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Wed 11/11

10:55 am-6:07 pm

3 stops55h 12m

Cancun

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$292
Quickest round-trip

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Sat 11/28

8:55 am-3:15 pm

1 stop6h 20m

Cancun

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$295

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Sun 11/15

6:30 am-11:07 pm

2 stops16h 37m

Cancun

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$296

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Sun 11/15

8:10 am-5:55 pm

1 stop9h 45m

Cancun

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$309

KnoxvilleMexico City

TYS Knoxville McGhee Tyson - MEX Mexico City Benito Juarez

TYSMEX

Knoxville McGhee Tyson

Sat 11/14

4:55 pm-7:45 pm

1 stop27h 50m

Mexico City Benito Juarez

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$313

KnoxvilleLeón

TYS Knoxville McGhee Tyson - BJX León Del Bajio

TYSBJX

Knoxville McGhee Tyson

Wed 12/23

6:12 pm-9:26 am

2 stops40h 14m

León Del Bajio

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, April is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $640). Flying from Knoxville to Mexico in December is currently the most expensive (average of $904). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from Knoxville to Mexico?

To ensure you get the cheapest price possible for a flight from Knoxville to Mexico, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Reviews of airlines servicing Mexico

Read through reviews of airlines operating flights from Knoxville to Mexico, such as Southwest,Delta, andAeromexico. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Mexico?

    A quick flight from Knoxville to Mexico can take about 8h 30m. Southwest provides one of the quickest options available for as low as $692. There are 1455 mi between Knoxville and Mexico. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Mexico?

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, April is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $640). Flying from Knoxville to Mexico in December is currently the most expensive (average of $904). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Knoxville to Mexico

Top 5 airlines flying from Knoxville to Mexico

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$406Average$763FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$485Average$583FlexibilityNo cancel feeOn-time63%
DeltaCheapest$526Average$729FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$531Average$773FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$544Average$741FlexibilityNo cancel feeOn-timeN/A

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