Mexico

$210+ Cheap flights from Knoxville (TYS) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
May 30 — Jun 61
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Cheap flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Expedia deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:19 pm
TYS
-
CUN
1 stop16h 45m
Frontier
Thu 6/43:39 pm
CUN
-
TYS
1 stop26h 54m
Frontier
Deal found 4/25$379
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:24 pm
TYS
-
CUN
2 stops19h 43m
Multiple Airlines
Thu 6/410:30 am
CUN
-
TYS
1 stop9h 00m
Multiple Airlines
Deal found 4/27$384
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/111:15 pm
TYS
-
CUN
2 stops21h 00m
Multiple Airlines
Sat 5/165:07 pm
CUN
-
TYS
1 stop18h 17m
Multiple Airlines
Deal found 4/25$386
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:32 pm
TYS
-
CUN
1 stop17h 17m
Frontier
Sun 7/193:35 pm
CUN
-
TYS
1 stop27h 01m
Frontier
Deal found 4/29$388
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:26 am
TYS
-
CUN
1 stop26h 55m
Multiple Airlines
Thu 8/1310:25 am
CUN
-
TYS
1 stop8h 14m
Multiple Airlines
Deal found 4/27$400
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:15 pm
TYS
-
CUN
1 stop27h 42m
Multiple Airlines
Fri 5/153:22 pm
CUN
-
TYS
2 stops18h 44m
Multiple Airlines
Deal found 4/28$402
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:32 pm
TYS
-
CUN
1 stop17h 16m
Frontier
Thu 6/183:35 pm
CUN
-
TYS
1 stop27h 02m
Frontier
Deal found 4/29$408
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:24 pm
TYS
-
CUN
2 stops38h 45m
Multiple Airlines
Mon 6/112:22 pm
CUN
-
TYS
1 stop26h 53m
Multiple Airlines
Deal found 4/27$417
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/53:38 pm
TYS
-
CUN
1 stop18h 40m
Multiple Airlines
Tue 7/1411:00 am
CUN
-
TYS
2 stops48h 09m
Multiple Airlines
Deal found 4/29$421
This Expedia deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:32 pm
TYS
-
CUN
1 stop16h 32m
Frontier
Thu 6/43:39 pm
CUN
-
TYS
1 stop26h 54m
Frontier
Deal found 4/27$424
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:24 pm
TYS
-
CUN
2 stops37h 57m
Multiple Airlines
Thu 6/410:30 am
CUN
-
TYS
1 stop9h 00m
Multiple Airlines
Deal found 4/25$426
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:20 pm
TYS
-
MEX
1 stop26h 25m
Multiple Airlines
Mon 7/1311:05 am
MEX
-
TYS
1 stop10h 28m
Multiple Airlines
Deal found 4/29$481

Find flight deals from Knoxville to Mexico

Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$379
(Expedia)

One-way from

$210
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$856
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
From Knoxville McGhee Tyson to Mexico
One-way flight from Knoxville McGhee Tyson to Mexico
Highest demand for flights based on searches. 14% potential increase in price ($116 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 6/15

7:22 pm-1:51 pm

2 stops19h 29m

Cancun

Thu 6/18

10:25 am-8:48 pm

1 stop9h 23m

$402

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 6/15

8:32 pm-12:48 pm

1 stop17h 16m

Cancun

Thu 6/18

3:35 pm-7:37 pm

1 stop27h 02m

$408

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

Wed 6/24

8:32 pm-6:05 pm

1 stop23h 33m

Monterrey Gen Mariano Escobedo

Tue 7/21

11:00 am-7:36 pm

1 stop30h 36m

$497

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 8/4

3:54 pm-8:15 pm

1 stop5h 21m

Cancun

Tue 8/11

12:35 pm-11:50 pm

2 stops10h 15m

$532

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Mon 6/22

8:32 pm-7:30 am

2 stops36h 58m

Guadalajara Miguel Hidal

Mon 6/29

7:57 am-11:34 pm

1 stop13h 37m

$560

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Fri 6/19

8:32 pm-4:25 pm

1 stop21h 53m

Guadalajara Miguel Hidal

Fri 6/26

6:25 am-11:34 pm

2 stops15h 09m

$567

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Thu 5/28

11:56 am-8:16 pm

1 stop9h 20m

Cancun

Wed 6/3

11:27 am-12:01 am

2 stops11h 34m

$573

KnoxvilleSan José del Cabo

TYS - SJD

TYSSJD

Knoxville McGhee Tyson

Mon 9/14

7:10 am-12:50 pm

2 stops8h 40m

San José del Cabo Los Cabos

Fri 9/25

1:10 pm-11:55 am

2 stops19h 45m

$584

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

Wed 7/8

8:32 pm-6:05 pm

1 stop23h 33m

Monterrey Gen Mariano Escobedo

Thu 7/30

8:50 am-12:03 pm

1 stop25h 13m

$586

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 6/15

8:32 pm-5:30 pm

1 stop22h 58m

Mexico City Benito Juarez

Tue 6/30

11:05 am-5:59 pm

2 stops28h 54m

$590

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Showing 1-10 of 53 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico

How far ahead should I book a flight from Knoxville to Mexico?

To ensure you get the cheapest price possible for a flight from Knoxville to Mexico, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $239). Flying from Knoxville to Mexico in April is currently the most expensive (average of $516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated April 30, 2026.
Read through reviews of airlines operating flights from Knoxville to Mexico, such as Delta,United Airlines, andAeromexico. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Mexico?

    A quick flight from Knoxville to Mexico can take about 5h 21m. Frontier provides one of the quickest options available for as low as $532. There are 1035 mi between Knoxville and Mexico. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Mexico?

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $239). Flying from Knoxville to Mexico in April is currently the most expensive (average of $516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Mexico

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Knoxville to Mexico

Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$620FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$473Average$774FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$482Average$686FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$492Average$621FlexibilityNo cancel feeOn-timeN/A

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