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$331+ Cheap flights from Mexico to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — TYS
May 31 — Jun 71
Sun 5/31
Sun 6/7
1 adult, Economy
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Cheap flight deals from Mexico to Knoxville

Cheapest flights from Mexico to Knoxville
Explore the most affordable flight options available from Mexico to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.

This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:12 am
SLP
-
TYS
1 stop12h 18m
United Airlines
Thu 9/35:45 am
TYS
-
SLP
2 stops15h 27m
United Airlines
Deal found 4/30$575
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:50 am
MLM
-
TYS
1 stop9h 15m
United Airlines
Mon 8/246:30 am
TYS
-
MLM
2 stops13h 43m
United Airlines
Deal found 4/26$576
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:49 pm
SLP
-
TYS
2 stops24h 53m
United Airlines
Mon 12/77:35 pm
TYS
-
SLP
2 stops17h 14m
United Airlines
Deal found 4/29$593
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:50 am
MLM
-
TYS
2 stops25h 59m
United Airlines
Mon 5/117:18 pm
TYS
-
MLM
2 stops24h 55m
United Airlines
Deal found 4/27$780

Find flight deals from Mexico to Knoxville

Keep the following information in mind while searching for Mexico to Knoxville flight deals. Data was last updated May 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$575
(United Airlines)

One-way from

$331
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$550
Provider with most accurate pricing for Mexico City Benito Juarez-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Knoxville McGhee Tyson flights.
Search Deals
From Mexico to Knoxville McGhee Tyson
Search Deals
One-way flight from Mexico to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Mexico to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 8/31

7:12 am-9:30 pm

1 stop12h 18m

Knoxville McGhee Tyson

Thu 9/3

5:45 am-7:12 pm

2 stops15h 27m

$575
Quickest round-trip

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Thu 8/20

6:50 am-6:05 pm

1 stop9h 15m

Knoxville McGhee Tyson

Mon 8/24

7:15 am-6:13 pm

1 stop12h 58m

$576
Cheapest one-way

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Sat 5/16

3:10 pm-8:50 pm

3 stops27h 40m

$331

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Wed 5/6

2:00 pm-8:50 pm

2 stops28h 50m

$402
Quickest one-way

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Wed 5/6

11:45 am-11:44 pm

1 stop9h 59m

$489

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Sorted by cheapest first

Best time to book a flight from Mexico to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Knoxville

What is the cheapest month to book a flight from Mexico to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Mexico to Knoxville (average of $451). Flying from Mexico to Knoxville in November is currently the most expensive (average of $582). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Mexico?

    If you book a flight to Knoxville from Mexico, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Mexico to Knoxville?

    A quick flight from Mexico to Knoxville can take about 12h 18m. United Airlines provides one of the quickest options available for as low as $575. Mexico and Knoxville are separated by a distance of 1382 mi.

  • Can I find deals for flights from Mexico to Knoxville that include hotel bookings?

    Yes. In addition to deals on Mexico to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Knoxville.

  • Can I find deals for business class flights from Mexico to Knoxville?

    Yes. Cheapflights offers flight deals from Mexico to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Mexico to Knoxville (average of $451). Flying from Mexico to Knoxville in November is currently the most expensive (average of $582). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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