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Guadalajara

$255+ Cheap flights from Knoxville (TYS) to Guadalajara (GDL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GDL
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Knoxville to Guadalajara

Cheapest flights from Knoxville to Guadalajara
Explore the most affordable flight options available from Knoxville to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:27 pm
TYS
-
GDL
1 stop23h 41m
Multiple Airlines
Fri 6/126:25 am
GDL
-
TYS
2 stops15h 09m
Multiple Airlines
Deal found 4/20$499
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:40 pm
TYS
-
GDL
2 stops27h 26m
Multiple Airlines
Mon 5/188:11 am
GDL
-
TYS
1 stop12h 13m
Multiple Airlines
Deal found 4/20$514
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:02 pm
TYS
-
GDL
2 stops26h 23m
Multiple Airlines
Wed 6/172:01 pm
GDL
-
TYS
1 stop25h 13m
Multiple Airlines
Deal found 4/20$625
This Aeromexico deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:40 am
TYS
-
GDL
1 stop7h 55m
Aeromexico
Mon 5/187:42 am
GDL
-
TYS
2 stops10h 46m
Aeromexico
Deal found 4/23$632
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:00 am
TYS
-
GDL
1 stop18h 00m
Multiple Airlines
Thu 4/307:13 am
GDL
-
TYS
2 stops32h 17m
Multiple Airlines
Deal found 4/19$641

Find flight deals from Knoxville to Guadalajara

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$499
(Kiwi.com)

One-way from

$255
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$673
Provider with most accurate pricing for Knoxville McGhee Tyson-Guadalajara Miguel Hidal flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guadalajara Miguel Hidal flights.
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From Knoxville McGhee Tyson to Guadalajara Miguel Hidal
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One-way flight from Knoxville McGhee Tyson to Guadalajara Miguel Hidal
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Highest demand for flights based on searches. 12% potential increase in price ($99 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in April 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Knoxville to Guadalajara that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 5/7

5:10 pm-5:24 pm

1 stop26h 14m

Guadalajara Miguel Hidal

Mon 5/18

8:11 am-10:24 pm

1 stop12h 13m

$558

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Wed 6/3

1:02 pm-1:25 pm

2 stops26h 23m

Guadalajara Miguel Hidal

Wed 6/17

2:01 pm-5:14 pm

1 stop25h 13m

$625
Quickest round-trip

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 5/14

5:40 am-11:35 am

1 stop7h 55m

Guadalajara Miguel Hidal

Mon 5/18

7:42 am-8:28 pm

2 stops10h 46m

$632

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Wed 6/3

12:10 pm-9:34 pm

1 stop11h 24m

Guadalajara Miguel Hidal

Wed 6/17

5:00 am-5:12 pm

1 stop10h 12m

$632

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 5/7

8:00 am-11:03 pm

2 stops17h 03m

Guadalajara Miguel Hidal

Mon 5/18

5:36 am-10:25 pm

2 stops14h 49m

$707

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Wed 6/3

5:40 am-4:45 pm

2 stops13h 05m

Guadalajara Miguel Hidal

Wed 6/17

7:41 am-11:54 pm

2 stops14h 13m

$722

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Sun 5/31

7:15 am-11:25 am

1 stop6h 10m

Guadalajara Miguel Hidal

Thu 6/4

6:40 am-11:12 pm

1 stop14h 32m

$782
Cheapest one-way

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Mon 5/25

8:19 pm-10:05 am

3 stops39h 46m

$262
Quickest one-way

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Mon 5/25

7:15 am-11:25 am

1 stop6h 10m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Knoxville-Guadalajara flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guadalajara flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guadalajara flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Guadalajara flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Guadalajara

Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guadalajara

How much does it cost to fly round-trip from Knoxville to Guadalajara?

Reviews of airlines servicing Guadalajara

Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated April 24, 2026.
See what other customers who have flown with American Airlines from Knoxville to Guadalajara have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,667 reviews

Comfort

7.2

Crew

7.9

Entertainment

6.9

Overall

7.1

Boarding

7.5

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,667 reviews
American Airlines
7.1
Good
11,667 reviews

Comfort

7.2

Crew

7.9

Entertainment

6.9

Overall

7.1

Boarding

7.5

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Guadalajara?

    A quick flight from Knoxville to Guadalajara can take about 7h 55m. Aeromexico provides one of the quickest options available for as low as $632. Airlines will cover a distance of 1574 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Guadalajara round-trip?

    Cheapflights users have booked flights from Knoxville to Guadalajara round-trip from $518. This flight start at 25% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Guadalajara that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guadalajara flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guadalajara?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guadalajara.

  • Can I find deals for business class flights from Knoxville to Guadalajara?

    Yes. Cheapflights offers flight deals from Knoxville to Guadalajara by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tlaquepaque

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Top airline flying from Knoxville to Guadalajara

Discover the top airline that operate flights from Knoxville to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$518Average$552FlexibilityNo cancel feeOn-time71%

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