$126+ Cheap flights from Knoxville (TYS) to Guadalajara (GDL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GDL
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Guadalajara with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Guadalajara
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One-way
Cheapest flights from Knoxville to GuadalajaraExplore the most affordable flight options available from Knoxville to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Knoxville to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:41 pm -
2 stops24h 46m
Sat 10/3111:47 pm -
1 stop8h 57m
Deal found 9/8![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
2 stops35h 27m
Sun 11/16:16 am -
1 stop14h 54m
Deal found 9/10![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:00 am -
1 stop15h 37m
Mon 12/710:27 am -
1 stop8h 58m
Deal found 9/12![Multiple Airlines logo]()
$537
This Aeromexico deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop8h 07m
Mon 12/72:12 pm -
1 stop6h 44m
Deal found 9/10![Aeromexico logo]()
$639
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:20 am -
1 stop12h 15m
Fri 9/253:34 pm -
2 stops40h 30m
Deal found 9/10![Multiple Airlines logo]()
$670
This Aeromexico deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:40 pm -
2 stops18h 01m
Sun 11/158:36 pm -
2 stops17h 39m
Deal found 9/11![Aeromexico logo]()
$685
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:30 pm -
1 stop17h 11m
Sun 11/153:48 pm -
1 stop6h 44m
Deal found 9/11![American Airlines logo]()
$730
This Aeromexico deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:40 am -
1 stop7h 49m
Sat 10/3112:55 pm -
1 stop7h 27m
Deal found 9/8![Aeromexico logo]()
$745
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:30 am -
1 stop10h 18m
Fri 1/156:00 am -
2 stops12h 00m
Deal found 9/8![American Airlines logo]()
$746
Best flights from Knoxville to GuadalajaraDiscover carefully curated flight deals from Knoxville to Guadalajara that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Knoxville to Guadalajara that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:07 am -
1 stop6h 43m
Mon 1/252:05 pm -
1 stop6h 40m
Deal found 9/9![Delta logo]()
$705
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:52 pm -
2 stops15h 49m
Fri 1/156:00 am -
2 stops12h 00m
Deal found 9/8![American Airlines logo]()
$746
This Aeromexico deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 am -
2 stops16h 04m
Mon 10/195:46 am -
2 stops12h 22m
Deal found 9/10![Aeromexico logo]()
$771
This deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/197:07 am -
1 stop6h 43m
Fri 1/222:05 pm -
1 stop6h 40m
Deal found 9/9![Delta logo]()
$709
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 am -
1 stop7h 50m
Mon 10/1912:55 pm -
1 stop9h 03m
Deal found 9/11![Delta logo]()
$840
Last-minute flights from Knoxville to GuadalajaraDiscover last-minute flight deals from Knoxville to Guadalajara. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Guadalajara. Data last updated September 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:20 am -
1 stop12h 15m
Fri 9/253:34 pm -
2 stops40h 30m
Deal found 9/10![Multiple Airlines logo]()
$670
This Aeromexico deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 am -
2 stops16h 04m
Mon 10/1912:55 pm -
1 stop9h 03m
Deal found 9/10![Aeromexico logo]()
$771
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 am -
1 stop7h 50m
Mon 10/1912:55 pm -
1 stop9h 03m
Deal found 9/11![Delta logo]()
$840
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:42 am -
2 stops26h 43m
Mon 10/1912:30 pm -
2 stops30h 19m
Deal found 9/12![United Airlines logo]()
$866
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:41 pm -
2 stops24h 46m
Sat 10/3111:47 pm -
1 stop8h 57m
Deal found 9/8![Multiple Airlines logo]()
$419
This Aeromexico deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:40 am -
1 stop7h 49m
Sat 10/3112:55 pm -
1 stop7h 27m
Deal found 9/8![Aeromexico logo]()
$745
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:05 pm -
2 stops18h 36m
Sat 10/316:00 am -
2 stops14h 59m
Deal found 9/8![American Airlines logo]()
$759
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:29 pm -
1 stop26h 29m
Sun 11/16:16 am -
1 stop14h 54m
Deal found 9/10![Multiple Airlines logo]()
$462
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:00 am -
2 stops14h 03m
Sun 11/13:48 pm -
2 stops16h 57m
Deal found 9/10![American Airlines logo]()
$869
One-way flights from Knoxville to GuadalajaraSearch for one-way flight options from Knoxville to Guadalajara. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Knoxville to Guadalajara. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:45 am -
1 stop28h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:41 pm -
2 stops24h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:37 pm -
2 stops27h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$215
This Aeromexico deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:40 am -
1 stop7h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Aeromexico logo]()
$391
Find flight deals from Knoxville to Guadalajara
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $419 (Kiwi.com) |
One-way from | $126 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Knoxville to Guadalajara that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Thu 11/12
7:45 am-11:06 am
1 stop28h 21m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Sat 10/24
4:41 pm-3:27 pm
2 stops24h 46m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$186
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Sun 10/11
1:37 pm-3:27 pm
2 stops27h 50m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$215
Quickest round-trip
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Sat 10/24
5:40 am-11:29 am
1 stop7h 49m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$391
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Thu 1/21
7:07 am-12:50 pm
1 stop6h 43m
Guadalajara Miguel Hidal
Mon 1/25
2:05 pm-9:45 pm
1 stop6h 40m
$705
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Tue 1/19
7:07 am-12:50 pm
1 stop6h 43m
Guadalajara Miguel Hidal
Fri 1/22
2:05 pm-9:45 pm
1 stop6h 40m
$709
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Tue 12/8
8:52 pm-11:41 am
2 stops15h 49m
Guadalajara Miguel Hidal
Fri 1/15
6:00 am-7:00 pm
2 stops12h 00m
$746
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Thu 10/1
5:40 am-7:44 pm
2 stops16h 04m
Guadalajara Miguel Hidal
Mon 10/19
5:46 am-8:08 pm
2 stops12h 22m
$771
KnoxvilleGuadalajara
TYS Knoxville McGhee Tyson - GDL Guadalajara Miguel Hidal
TYSGDL
Knoxville McGhee Tyson
Thu 10/1
5:40 am-11:30 am
1 stop7h 50m
Guadalajara Miguel Hidal
Mon 10/19
12:55 pm-11:58 pm
1 stop9h 03m
$840
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Knoxville-Guadalajara flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guadalajara flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guadalajara flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Guadalajara flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Guadalajara
Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Knoxville with our price prediction graph.
TYS-GDL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guadalajara
Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated September 13, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Guadalajara have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guadalajara?
Book flights to Guadalajara if you plan to visit one of these locationsTlaquepaque
Zapopan
Tequila
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Other flights to Guadalajara
Explore flights to Guadalajara departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
Knoxville and Guadalajara flights
Browse other Knoxville and Guadalajara flight options. Last updated on September 13, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Knoxville to Guadalajara
Discover the top 3 airlines that operate flights from Knoxville to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$520 | Average$803 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$601 | Average$832 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$653 | Average$788 | FlexibilityNo cancel fee | On-timeN/A |