Mexico

$157+ Cheap flights from Knoxville (TYS) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Apr 16 — Apr 231
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Cheap flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:02 pm
TYS
-
CUN
1 stop21h 10m
Multiple Airlines
Thu 3/269:12 am
CUN
-
TYS
1 stop12h 47m
Multiple Airlines
Deal found 3/13$373
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:27 am
TYS
-
CUN
1 stop24h 14m
Multiple Airlines
Fri 5/81:43 pm
CUN
-
TYS
1 stop20h 23m
Multiple Airlines
Deal found 3/12$387
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:15 pm
TYS
-
CUN
1 stop19h 56m
Multiple Airlines
Tue 4/1412:35 pm
CUN
-
TYS
1 stop21h 01m
Multiple Airlines
Deal found 3/13$399
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:27 am
TYS
-
CUN
1 stop24h 14m
Multiple Airlines
Sun 5/171:43 pm
CUN
-
TYS
1 stop21h 42m
Multiple Airlines
Deal found 3/12$402
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:30 pm
TYS
-
MEX
2 stops28h 30m
Multiple Airlines
Mon 6/811:05 am
MEX
-
TYS
1 stop10h 34m
Multiple Airlines
Deal found 3/14$402
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:00 am
TYS
-
CUN
2 stops26h 41m
Multiple Airlines
Sun 3/292:39 pm
CUN
-
TYS
1 stop16h 29m
Multiple Airlines
Deal found 3/12$408
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:03 pm
TYS
-
MEX
1 stop27h 42m
Multiple Airlines
Mon 6/811:05 am
MEX
-
TYS
1 stop10h 34m
Multiple Airlines
Deal found 3/14$411
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:22 pm
TYS
-
MEX
1 stop23h 23m
Multiple Airlines
Sat 5/2312:50 am
MEX
-
TYS
1 stop14h 23m
Multiple Airlines
Deal found 3/12$415
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:32 pm
TYS
-
MEX
1 stop22h 58m
Multiple Airlines
Mon 6/811:05 am
MEX
-
TYS
1 stop10h 34m
Multiple Airlines
Deal found 3/14$427
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:30 pm
TYS
-
MEX
1 stop20h 50m
Multiple Airlines
Fri 6/56:20 am
MEX
-
TYS
1 stop14h 20m
Multiple Airlines
Deal found 3/14$432
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
TYS
-
MEX
1 stop27h 02m
Multiple Airlines
Thu 5/711:05 am
MEX
-
TYS
1 stop28h 25m
Multiple Airlines
Deal found 3/16$434
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:30 pm
TYS
-
MEX
1 stop20h 50m
Multiple Airlines
Wed 6/1012:50 am
MEX
-
TYS
1 stop14h 24m
Multiple Airlines
Deal found 3/14$435

Find flight deals from Knoxville to Mexico

Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$387
(Kiwi.com)

One-way from

$157
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$845
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
From Knoxville McGhee Tyson to Mexico
One-way flight from Knoxville McGhee Tyson to Mexico
Highest demand for flights based on searches. 14% potential increase in price ($117 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 4/30

4:28 pm-5:30 pm

1 stop27h 02m

Mexico City Benito Juarez

Thu 5/7

11:05 am-5:30 pm

1 stop28h 25m

$434

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sun 9/6

5:30 am-12:50 pm

1 stop8h 20m

Cancun

Wed 9/16

8:00 am-6:17 pm

1 stop9h 17m

$549
Quickest round-trip

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 5/4

4:38 pm-8:15 pm

1 stop4h 37m

Cancun

Thu 5/7

8:00 am-2:33 pm

1 stop5h 33m

$549

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sat 5/30

6:40 am-3:00 pm

2 stops9h 20m

Cancun

Sat 6/6

11:00 am-9:20 pm

1 stop9h 20m

$557

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 4/6

6:30 am-2:25 pm

1 stop8h 55m

Cancun

Wed 4/8

1:05 pm-8:50 pm

1 stop6h 45m

$561

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Thu 5/28

3:30 pm-8:16 pm

1 stop5h 46m

Cancun

Wed 6/3

8:00 am-2:33 pm

1 stop5h 33m

$584

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Fri 6/26

10:05 am-8:23 pm

1 stop11h 18m

Cancun

Fri 7/3

12:35 pm-9:28 pm

1 stop7h 53m

$584

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Wed 4/15

5:40 am-2:51 pm

2 stops11h 11m

Guadalajara Miguel Hidal

Thu 10/15

9:15 am-11:46 pm

2 stops12h 31m

$585

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Fri 4/10

5:40 am-3:10 pm

2 stops10h 30m

Cancun

Tue 4/14

12:25 pm-11:54 pm

2 stops10h 29m

$589

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Wed 4/15

5:40 am-11:37 am

1 stop7h 57m

Guadalajara Miguel Hidal

Thu 10/15

1:00 pm-9:45 pm

1 stop6h 45m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Showing 1-10 of 58 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $192). Flying from Knoxville to Mexico in February is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated March 17, 2026.
Read through reviews of airlines operating flights from Knoxville to Mexico, such as Delta,United Airlines, andAeromexico. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Mexico?

    A quick flight from Knoxville to Mexico can take about 8h 20m. Delta provides one of the quickest options available for as low as $549. There are 1035 mi between Knoxville and Mexico. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Mexico?

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $192). Flying from Knoxville to Mexico in February is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Mexico

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Knoxville to Mexico

Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$619FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$455Average$647FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$473Average$761FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$487Average$607FlexibilityNo cancel feeOn-timeN/A

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