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$164+ Cheap flights from Knoxville (TYS) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
nov 29 — dez 61
sáb 11/29
sáb 12/6
1 adult, Economy
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Cheap flight deals from Knoxville to Mexico

Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated outubro 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$394
(Kiwi.com)

One-way from

$164
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$649
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
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From Knoxville McGhee Tyson to Mexico
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One-way flight from Knoxville McGhee Tyson to Mexico
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Highest demand for flights based on searches. 13% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/274:27 pmTYS - CUN
1 stop21h 08mMultiple Airlines
qui 12/42:36 pmCUN - TYS
1 stop17h 57mMultiple Airlines
Deal found 10/28$394
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 12/209:23 pmTYS - CUN
1 stop16h 08mMultiple Airlines
qua 12/244:58 pmCUN - TYS
1 stop22h 33mMultiple Airlines
Deal found 10/27$418
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 12/1312:53 pmTYS - CUN
2 stops24h 16mMultiple Airlines
sáb 12/202:36 pmCUN - TYS
1 stop5h 57mMultiple Airlines
Deal found 10/29$432
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/55:56 pmTYS - MTY
1 stop17h 14mMultiple Airlines
seg 12/811:00 amMTY - TYS
1 stop7h 14mMultiple Airlines
Deal found 10/29$437
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/412:43 pmTYS - MEX
2 stops34h 17mMultiple Airlines
seg 12/88:30 amMEX - TYS
2 stops9h 44mMultiple Airlines
Deal found 10/29$451
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 11/229:53 amTYS - CUN
1 stop7h 20mMultiple Airlines
qua 11/2611:53 amCUN - TYS
1 stop10h 16mMultiple Airlines
Deal found 10/29$462
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/27:35 amTYS - CUN
1 stop7h 14mAmerican Airlines
ter 12/95:20 pmCUN - TYS
1 stop6h 37mAmerican Airlines
Deal found 10/28$486
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/304:46 pmTYS - MEX
1 stop25h 19mMultiple Airlines
seg 1/1210:00 pmMEX - TYS
2 stops40h 57mMultiple Airlines
Deal found 10/29$499
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/304:46 pmTYS - MEX
1 stop25h 19mMultiple Airlines
ter 1/136:40 amMEX - TYS
2 stops32h 17mMultiple Airlines
Deal found 10/29$506
This Aeromexico deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/312:00 pmTYS - MEX
1 stop8h 50mAeromexico
ter 1/138:25 amMEX - TYS
2 stops14h 20mAeromexico
Deal found 10/29$543
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/312:00 pmTYS - MEX
1 stop8h 50mDelta
qua 1/148:20 amMEX - TYS
2 stops9h 32mDelta
Deal found 10/29$548
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/154:52 pmTYS - GDL
1 stop28h 48mMultiple Airlines
ter 12/239:18 pmGDL - TYS
2 stops41h 13mMultiple Airlines
Deal found 10/28$565

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 30, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.

Fly from

Knoxville

Fly to

Mexico

Route

Depart

Return

Price

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

qui 11/27

4:27 pm-1:35 pm

1 stop21h 08m

Cancun

qui 12/4

2:36 pm-8:33 am

1 stop17h 57m

$394

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

sáb 12/20

9:23 pm-1:31 pm

1 stop16h 08m

Cancun

qua 12/24

4:58 pm-3:31 pm

1 stop22h 33m

$418

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

sáb 1/10

5:30 pm-12:27 pm

2 stops18h 57m

Cancun

sáb 1/17

3:00 pm-5:53 pm

2 stops26h 53m

$422

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

sáb 12/13

12:53 pm-1:09 pm

2 stops24h 16m

Cancun

sáb 12/20

2:36 pm-8:33 pm

1 stop5h 57m

$432

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

sex 12/5

5:56 pm-10:10 am

1 stop17h 14m

Monterrey Gen Mariano Escobedo

seg 12/8

11:00 am-7:14 pm

1 stop7h 14m

$437

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

ter 4/14

7:00 am-12:19 pm

1 stop7h 19m

Cozumel

ter 4/21

1:21 pm-11:19 pm

1 stop7h 58m

$482

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

ter 4/14

8:44 pm-12:39 pm

2 stops17h 55m

Cozumel

ter 4/21

3:15 pm-10:01 am

2 stops16h 46m

$486

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

ter 1/13

8:25 am-4:45 pm

1 stop8h 20m

Cancun

ter 2/3

12:40 pm-11:09 pm

1 stop10h 29m

$486

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

sáb 12/6

8:13 pm-12:16 pm

1 stop16h 03m

Cancun

sex 12/12

5:20 pm-11:57 pm

1 stop6h 37m

$486

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

ter 12/2

6:05 am-1:24 pm

1 stop7h 19m

Cancun

ter 12/9

11:50 am-11:57 pm

1 stop12h 07m

$486

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $253). Flying from Knoxville to Mexico in July is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MX?

Find hourly flight availability from Knoxville to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated outubro 30, 2025.

It’s typically best to fly out from Knoxville to Mexico in the evening. Doing so could potentially save you 28% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated outubro 30, 2025.
Read through reviews of airlines operating flights from Knoxville to Mexico, such as Delta, United Airlines, and Aeromexico. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Aeromexico
7.4
Good
1,674 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Mexico?

    A quick flight from Knoxville to Mexico can take about 7h 19m. United Airlines provides one of the quickest options available for as low as $482. There are 1071 mi between Knoxville and Mexico. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Mexico one-way?

    $269 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and Aeromexico, with prices starting from $294 and $316, respectively.

  • What are the most popular routes from Knoxville to Mexico?

    The most popular route from Knoxville to Mexico is Knoxville McGhee Tyson - Cancun. You may also consider Knoxville McGhee Tyson - Cozumel or Knoxville McGhee Tyson - Mexico City Benito Juarez.

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $253). Flying from Knoxville to Mexico in July is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Mexico

Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$682FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$455Average$629FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$477Average$660FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$479Average$570FlexibilityNo cancel feeOn-timeN/A

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