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$375+ Cheap flights from Knoxville (TYS) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Jan 1 — Jan 81
Thu 1/1
Thu 1/8
1 adult, Economy
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Cheap flight deals from Knoxville to Mexico City

Cheapest flights from Knoxville to Mexico City
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 2, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:42 pmTYS - MEX
1 stop27h 03mMultiple Airlines
Fri 1/910:20 pmMEX - TYS
2 stops42h 33mMultiple Airlines
Deal found 11/30$495
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:42 pmTYS - MEX
1 stop27h 03mMultiple Airlines
Thu 1/810:20 pmMEX - TYS
2 stops23h 08mMultiple Airlines
Deal found 11/30$550
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:42 pmTYS - MEX
1 stop27h 03mMultiple Airlines
Wed 1/710:00 pmMEX - TYS
2 stops19h 36mMultiple Airlines
Deal found 11/30$576
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:30 amTYS - MEX
1 stop14h 15mMultiple Airlines
Fri 1/910:20 pmMEX - TYS
2 stops33h 19mMultiple Airlines
Deal found 11/30$577
This Mytrip deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:30 amTYS - MEX
1 stop11h 35mMultiple Airlines
Sat 12/63:00 pmMEX - TYS
3 stops30h 22mMultiple Airlines
Deal found 11/30$590
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:46 pmTYS - MEX
1 stop26h 59mMultiple Airlines
Wed 1/78:10 amMEX - TYS
1 stop30h 18mMultiple Airlines
Deal found 11/30$625
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:30 amTYS - MEX
1 stop14h 15mMultiple Airlines
Thu 1/810:20 pmMEX - TYS
2 stops23h 08mMultiple Airlines
Deal found 11/30$631
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:08 amTYS - MEX
2 stops11h 52mMultiple Airlines
Fri 1/911:10 amMEX - TYS
1 stop10h 18mMultiple Airlines
Deal found 11/30$632
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:29 amTYS - MEX
1 stop9h 16mMultiple Airlines
Sun 12/78:10 amMEX - TYS
1 stop30h 47mMultiple Airlines
Deal found 11/30$637
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amTYS - MEX
1 stop14h 45mMultiple Airlines
Wed 1/710:00 pmMEX - TYS
2 stops35h 10mMultiple Airlines
Deal found 11/30$647

Find flight deals from Knoxville to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$406
(Kiwi.com)

One-way from

$375
(American Airlines)

Popular in

December

Cheapest in

April

Average price

$846
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
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From Knoxville McGhee Tyson to Mexico City Benito Juarez
Search Deals
One-way flight from Knoxville McGhee Tyson to Mexico City Benito Juarez
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($108 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 2, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.

Fly from

Knoxville

Fly to

Mexico City

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 1/15

8:18 pm-5:05 pm

1 stop21h 47m

Mexico City Benito Juarez

Thu 1/22

7:20 pm-11:09 am

2 stops38h 49m

$406

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 1/14

5:40 am-11:20 am

1 stop6h 40m

Mexico City Benito Juarez

Thu 1/22

11:05 am-11:45 pm

2 stops11h 40m

$550

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 1/13

8:25 am-8:50 pm

1 stop13h 25m

Mexico City Benito Juarez

Wed 1/21

4:35 pm-9:21 am

1 stop15h 46m

$550

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 1/14

6:59 am-2:20 pm

1 stop8h 21m

Mexico City Benito Juarez

Tue 1/20

9:40 am-7:27 pm

1 stop8h 47m

$550

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 1/13

11:05 am-8:50 pm

1 stop10h 45m

Mexico City Benito Juarez

Thu 1/22

8:40 am-3:19 pm

1 stop5h 39m

$550

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 1/15

7:00 am-4:25 pm

2 stops10h 25m

Mexico City Benito Juarez

Thu 1/22

2:10 pm-11:45 pm

1 stop8h 35m

$550

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 1/13

5:40 am-2:35 pm

2 stops9h 55m

Mexico City Benito Juarez

Tue 1/20

6:40 am-5:56 pm

2 stops10h 16m

$555

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 1/14

5:40 am-4:35 pm

2 stops11h 55m

Mexico City Benito Juarez

Wed 1/21

12:35 pm-11:45 pm

1 stop10h 10m

$555

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 12/9

5:24 am-9:55 pm

1 stop17h 31m

$375

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 12/9

4:52 pm-9:10 pm

3 stops53h 18m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Compare providers for flights from Knoxville to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Mexico City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Mexico City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Mexico City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Mexico City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City

What is the cheapest month to book a flight from Knoxville to Mexico City?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $605). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated December 2, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,041 reviews
Delta
7.9
Good
8,010 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Mexico City?

    A quick flight from Knoxville to Mexico City can take about 6h 40m. Aeromexico provides one of the quickest options available for as low as $550. Airlines will cover a distance of 1455 mi.

  • What are the cheapest airlines flying from Knoxville to Mexico City round-trip?

    Cheapflights users have booked flights from Knoxville to Mexico City round-trip from $318. Another airline that can offer you cheap pricing is American Airlines. Users have found that Delta is 50% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Mexico City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City.

  • Can I find deals for business class flights from Knoxville to Mexico City?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico City?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $605). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Taxco

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Alternative routes for Knoxville to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Mexico City

Discover the top 2 airlines that operate flights from Knoxville to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$580FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$455Average$722FlexibilityNo cancel feeOn-time71%

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