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$318+ Cheap flights from Knoxville (TYS) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
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Cheap flight deals from Knoxville to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 14, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$440
(Kiwi.com)

One-way from

$318
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$687
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
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From Knoxville McGhee Tyson to Mexico City Benito Juarez
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One-way flight from Knoxville McGhee Tyson to Mexico City Benito Juarez
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Highest demand for flights based on searches. 17% potential increase in price ($132 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Knoxville to Mexico City

Cheapest flights from Knoxville to Mexico City
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:30 am
TYS
-
MEX
2 stops37h 15m
Multiple Airlines
Thu 3/58:10 am
MEX
-
TYS
1 stop30h 15m
Multiple Airlines
Deal found 1/12$523
This SmartFares deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:00 pm
TYS
-
MEX
1 stop9h 50m
Aeromexico
Thu 3/52:10 pm
MEX
-
TYS
1 stop6h 06m
Aeromexico
Deal found 1/12$532
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:00 pm
TYS
-
MEX
2 stops10h 35m
Delta
Thu 3/510:35 am
MEX
-
TYS
2 stops12h 17m
Delta
Deal found 1/12$557
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:04 pm
TYS
-
MEX
2 stops28h 41m
Multiple Airlines
Fri 2/208:10 am
MEX
-
TYS
1 stop10h 17m
Multiple Airlines
Deal found 1/13$560
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:39 pm
TYS
-
MEX
2 stops33h 51m
Multiple Airlines
Wed 2/1110:45 am
MEX
-
TYS
1 stop30h 07m
Multiple Airlines
Deal found 1/13$565
This SmartFares deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/511:58 am
TYS
-
MEX
1 stop9h 52m
Aeromexico
Wed 2/118:40 am
MEX
-
TYS
1 stop5h 41m
Aeromexico
Deal found 1/13$572
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:21 pm
TYS
-
MEX
1 stop8h 14m
American Airlines
Wed 3/115:00 am
MEX
-
TYS
2 stops9h 31m
American Airlines
Deal found 1/12$597
This Aeromexico deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/174:00 pm
TYS
-
MEX
1 stop7h 21m
Aeromexico
Sun 5/247:05 am
MEX
-
TYS
1 stop6h 01m
Aeromexico
Deal found 1/12$603
This Aeromexico deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/178:30 am
TYS
-
MEX
2 stops8h 45m
Aeromexico
Fri 2/2011:05 am
MEX
-
TYS
2 stops7h 55m
Aeromexico
Deal found 1/13$613
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:02 am
TYS
-
MEX
1 stop15h 53m
American Airlines
Wed 5/2011:20 am
MEX
-
TYS
1 stop10h 36m
American Airlines
Deal found 1/13$618
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/74:55 pm
TYS
-
MEX
1 stop8h 15m
United Airlines
Sat 2/2110:05 am
MEX
-
TYS
1 stop8h 50m
United Airlines
Deal found 1/13$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.

Fly from

Knoxville

Fly to

Mexico City

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 2/26

6:30 am-6:45 pm

2 stops37h 15m

Mexico City Benito Juarez

Thu 3/5

8:10 am-3:25 pm

1 stop30h 15m

$523

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 2/26

12:00 pm-8:50 pm

1 stop9h 50m

Mexico City Benito Juarez

Thu 3/5

2:10 pm-9:16 pm

1 stop6h 06m

$532

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 2/26

1:00 pm-10:35 pm

2 stops10h 35m

Mexico City Benito Juarez

Thu 3/5

10:35 am-11:52 pm

2 stops12h 17m

$557

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 2/17

4:04 pm-7:45 pm

2 stops28h 41m

Mexico City Benito Juarez

Fri 2/20

8:10 am-7:27 pm

1 stop10h 17m

$560

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 3/8

12:21 pm-10:22 pm

1 stop12h 01m

Mexico City Benito Juarez

Wed 3/11

7:00 am-3:32 pm

1 stop6h 32m

$593

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 2/5

8:25 am-7:25 pm

2 stops12h 00m

Mexico City Benito Juarez

Wed 2/11

9:05 am-11:45 pm

2 stops13h 40m

$593

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 5/17

4:00 pm-9:21 pm

1 stop7h 21m

Mexico City Benito Juarez

Sun 5/24

7:05 am-3:06 pm

1 stop6h 01m

$603

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 2/17

8:30 am-4:15 pm

2 stops8h 45m

Mexico City Benito Juarez

Fri 2/20

11:05 am-8:00 pm

2 stops7h 55m

$613

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 2/12

7:02 am-9:55 pm

1 stop15h 53m

Mexico City Benito Juarez

Wed 5/20

11:20 am-11:56 pm

1 stop10h 36m

$618

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sat 2/7

9:30 am-6:55 pm

2 stops10h 25m

Mexico City Benito Juarez

Sat 2/21

5:45 am-1:46 pm

1 stop7h 01m

$623

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 12 results
1
2

Compare providers for flights from Knoxville to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Mexico City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
SmartFaresPrice Accuracy1 starTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Mexico City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Mexico City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Mexico City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City

What is the cheapest month to book a flight from Knoxville to Mexico City?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $597). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated January 14, 2026.
Read reviews from past customers who have flown Delta, Aeromexico, and American Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,039 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,039 reviews
Delta
7.9
Good
8,039 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Aeromexico
7.4
Good
1,596 reviews
Delta
7.9
Good
8,039 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,117 reviews
Delta
7.9
Good
8,039 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Mexico City?

    A quick flight from Knoxville to Mexico City can take about 9h 50m. Aeromexico provides one of the quickest options available for as low as $532. Airlines will cover a distance of 1455 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Mexico City round-trip?

    Cheapflights users have booked flights from Knoxville to Mexico City round-trip from $318. Other airlines that can offer you cheap pricing are American Airlines, from $455, and Aeromexico, from $487. Users have found that Delta is 50% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Mexico City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City.

  • Can I find deals for business class flights from Knoxville to Mexico City?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico City?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $597). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Taxco

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Mexico City flights
Memphis to Mexico City flights
Blountville to Mexico City flights

Top 3 airlines flying from Knoxville to Mexico City

Discover the top 3 airlines that operate flights from Knoxville to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$582FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$455Average$657FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$487Average$642FlexibilityNo cancel feeOn-timeN/A

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