What are the cheapest airlines flying from Knoxville to Mexico City round-trip?

Cheapflights users have booked flights from Knoxville to Mexico City round-trip from $455. Other airlines that can offer you cheap pricing are Delta, from $462, and Aeromexico, from $487. Users have found that American Airlines is 34% cheaper than the other options available to this destination.

What is the cheapest day to fly from Knoxville to Mexico City?

Travelers seeking maximum savings on their Knoxville to Mexico City flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Knoxville to Mexico City?

Before booking your flight from Knoxville to Mexico City check out the most popular airlines for this route: American Airlines, Aeromexico or Delta.

What is the cheapest day to fly round-trip from Knoxville to Mexico City?

Sunday flights are generally found to be more expensive for flights from Knoxville to Mexico City. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Mexico City.

What is the cheapest month to fly from Knoxville to Mexico City?

Flights from Knoxville to Mexico City lean towards being more expensive in December. Prices are generally better when you fly from Knoxville to Mexico City in April, with the cheapest ticket starting at $487.

Can I find deals for flights from Knoxville to Mexico City that include hotel bookings?

Yes. In addition to deals on Knoxville to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Mexico City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City.

Can I find deals for business class flights from Knoxville to Mexico City?

Yes. Cheapflights offers flight deals from Knoxville to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$157+ Cheap Flights from Knoxville to Mexico City

Q: How much does it cost to fly round-trip from Knoxville to Mexico City?

Airfare is below average for this route at the moment. Knoxville to Mexico City flights typically cost between $544 and $681 in September. The cheapest round-trip price found within the last 3 days was $485 on Multiple Airlines (Sep 28-Oct 5).

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Cheap flight deals from Knoxville to Mexico City

Round-trip from	$485 (Kiwi.com)
One-way from	$157 (Kiwi.com)
Popular in	December
Cheapest in	April
Average price	$566

From Knoxville McGhee Tyson to Mexico City Benito Juarez

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One-way flight from Knoxville McGhee Tyson to Mexico City Benito Juarez

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Highest demand for flights based on searches. 23% potential increase in price ($210 potential increase over avg. RT price).

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Cheapest flight prices on average. 8% potential price decrease ($55 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Knoxville to Mexico City

Cheapest flights from Knoxville to Mexico City
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Thu 9/47:00 amTYS - MEX

1 stop12h 00mMultiple Airlines

Sun 9/145:25 amMEX - TYS

2 stops15h 25mMultiple Airlines

Deal found 8/11

$458

Fri 9/261:22 pmTYS - MEX

2 stops17h 28mMultiple Airlines

Fri 10/311:05 amMEX - TYS

1 stop10h 31mMultiple Airlines

Deal found 8/12

$481

Sun 9/287:00 amTYS - MEX

1 stop12h 00mMultiple Airlines

Sun 10/55:25 amMEX - TYS

2 stops15h 17mMultiple Airlines

Deal found 8/14

$485

Wed 9/245:45 amTYS - MEX

1 stop6h 10mDelta

Mon 9/293:30 pmMEX - TYS

1 stop6h 14mDelta

Deal found 8/14

$542

Fri 8/155:47 pmTYS - MEX

1 stop20h 28mMultiple Airlines

Fri 8/2211:05 amMEX - TYS

1 stop10h 07mMultiple Airlines

Deal found 8/14

$558

Best flights from Knoxville to Mexico City
Discover carefully curated flight deals from Knoxville to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Sun 9/287:00 amTYS - MEX

1 stop12h 00mMultiple Airlines

Sun 10/55:25 amMEX - TYS

2 stops15h 17mMultiple Airlines

Deal found 8/14

$485

Wed 9/2410:24 amTYS - MEX

1 stop5h 46mAeromexico

Mon 9/298:25 amMEX - TYS

2 stops9h 37mAeromexico

Deal found 8/13

$542

Wed 9/2410:24 amTYS - MEX

1 stop11h 16mDelta

Mon 9/293:30 pmMEX - TYS

1 stop6h 14mDelta

Deal found 8/13

$542

Thu 8/285:30 amTYS - MEX

1 stop12h 45mAmerican Airlines

Sun 8/315:00 amMEX - TYS

1 stop16h 53mAmerican Airlines

Deal found 8/13

$697

Thu 8/2810:00 amTYS - MEX

1 stop9h 30mMultiple Airlines

Sun 8/316:20 amMEX - TYS

2 stops12h 02mMultiple Airlines

Deal found 8/13

$581

Sun 9/285:45 amTYS - MEX

2 stops11h 50mDelta

Sun 10/510:00 amMEX - TYS

2 stops11h 44mDelta

Deal found 8/14

$587

Last-minute flights from Knoxville to Mexico City
Discover last-minute flight deals from Knoxville to Mexico City. Data last updated August 14, 2025 and is based on user searches.

Fri 8/155:47 pmTYS - MEX

1 stop20h 28mMultiple Airlines

Fri 8/2211:05 amMEX - TYS

1 stop10h 07mMultiple Airlines

Deal found 8/14

$558

Thu 9/47:00 amTYS - MEX

1 stop12h 00mMultiple Airlines

Sun 9/145:25 amMEX - TYS

2 stops15h 25mMultiple Airlines

Deal found 8/11

$458

Wed 9/245:45 amTYS - MEX

1 stop6h 10mDelta

Mon 9/293:30 pmMEX - TYS

1 stop6h 14mDelta

Deal found 8/14

$542

Fri 9/261:22 pmTYS - MEX

2 stops17h 28mMultiple Airlines

Fri 10/311:05 amMEX - TYS

1 stop10h 31mMultiple Airlines

Deal found 8/12

$481

Sun 9/287:00 amTYS - MEX

1 stop12h 00mMultiple Airlines

Sun 10/55:25 amMEX - TYS

2 stops15h 17mMultiple Airlines

Deal found 8/14

$485

One-way flights from Knoxville to Mexico City
Search for one-way flight options from Knoxville to Mexico City. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Sun 8/3110:00 amTYS - MEX

1 stop9h 30mMultiple Airlines

Deal found 8/12

$157

Thu 9/47:00 amTYS - MEX

1 stop12h 00mMultiple Airlines

Deal found 8/12

$172

Sat 9/64:31 pmTYS - MEX

2 stops31h 29mMultiple Airlines

Deal found 8/12

$176

Wed 10/154:26 pmTYS - MEX

2 stops31h 34mMultiple Airlines

Deal found 8/13

$188

Fri 9/56:24 pmTYS - MEX

1 stop18h 11mMultiple Airlines

Deal found 8/12

$197

Tue 9/23:22 pmTYS - MEX

2 stops32h 38mMultiple Airlines

Deal found 8/12

$209

Mon 9/19:56 pmTYS - MEX

1 stop23h 39mMultiple Airlines

Deal found 8/12

$211

Wed 9/34:55 pmTYS - MEX

2 stops21h 20mMultiple Airlines

Deal found 8/12

$225

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 9/28

7:00 am-5:00 pm

1 stop12h 00m

Mexico City Benito Juarez

Sun 10/5

5:25 am-10:42 pm

2 stops15h 17m

$485

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 9/24

10:24 am-2:10 pm

1 stop5h 46m

Mexico City Benito Juarez

Mon 9/29

8:25 am-8:02 pm

2 stops9h 37m

$542

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 9/24

10:24 am-7:40 pm

1 stop11h 16m

Mexico City Benito Juarez

Mon 9/29

3:30 pm-11:44 pm

1 stop6h 14m

$542

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 8/28

10:00 am-5:30 pm

1 stop9h 30m

Mexico City Benito Juarez

Sun 8/31

6:20 am-8:22 pm

2 stops12h 02m

$581

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 9/28

5:45 am-3:35 pm

2 stops11h 50m

Mexico City Benito Juarez

Sun 10/5

10:00 am-11:44 pm

2 stops11h 44m

$587

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 8/28

5:30 am-4:15 pm

1 stop12h 45m

Mexico City Benito Juarez

Sun 8/31

5:00 am-11:53 pm

1 stop16h 53m

$697

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 10/15

4:26 pm-10:00 pm

2 stops31h 34m

$188

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 9/4

8:35 am-2:10 pm

1 stop7h 35m

$299

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 10/15

7:05 am-4:15 pm

1 stop11h 10m

$299

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Fri 9/5

7:10 am-2:10 pm

1 stop9h 00m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 15 results

Best time to book a flight from Knoxville to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City

What is the cheapest month to book a flight from Knoxville to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $387). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MEX?

It’s typically best to fly out from Knoxville to Mexico City at noon. Doing so could potentially save you 24% on the flight price compared to flying in the afternoon, which is usually more expensive.

How much does it cost to fly round-trip from Knoxville to Mexico City?

Reviews of airlines servicing Mexico City

Read reviews from past customers who have flown Delta, Aeromexico, and United Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Aeromexico

7.5

Good

1,723 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,916 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Knoxville to Mexico City round-trip?
Cheapflights users have booked flights from Knoxville to Mexico City round-trip from $455. Other airlines that can offer you cheap pricing are Delta, from $462, and Aeromexico, from $487. Users have found that American Airlines is 34% cheaper than the other options available to this destination.
Can I find deals for flights from Knoxville to Mexico City that include hotel bookings?
Yes. In addition to deals on Knoxville to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Mexico City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City.
Can I find deals for business class flights from Knoxville to Mexico City?
Yes. Cheapflights offers flight deals from Knoxville to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Mexico City?
Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $387). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

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Other flights to Mexico City

Top 4 airlines flying from Knoxville to Mexico City

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$455	Average$698	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$462	Average$592	FlexibilityNo cancel fee	On-timeN/A
Aeromexico	Cheapest$487	Average$642	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$657	Average$657	FlexibilityNo cancel fee	On-time69%

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$157+ Cheap flights from Knoxville (TYS) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Mexico City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Mexico City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Mexico City

Cheapest flights from Knoxville to Mexico CityExplore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.

Best time to book a flight from Knoxville to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City

What is the cheapest month to book a flight from Knoxville to Mexico City?

What is the cheapest time of day to fly from TYS to MEX?

Find hourly flight availability from Knoxville to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

How much does it cost to fly round-trip from Knoxville to Mexico City?

Reviews of airlines servicing Mexico City

Read reviews from past customers who have flown Delta, Aeromexico, and United Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to Mexico City round-trip?

Can I find deals for flights from Knoxville to Mexico City that include hotel bookings?

How can I find direct flights from Knoxville to Mexico City?

Can I find deals for business class flights from Knoxville to Mexico City?

What is the cheapest month to book a flight from Knoxville to Mexico City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Knoxville to Mexico City

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Cheapest flights from Knoxville to Mexico City
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.