$486+ Cheap flights from Knoxville (TYS) to Mexico City (MEX)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Mar 26 — Apr 21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Mexico City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Mexico City
Cheapest
Best
Last-minute
Cheapest flights from Knoxville to Mexico CityExplore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:46 pm
TYS
- MEX
2 stops25h 59m
Multiple Airlines
Thu 4/911:05 am
MEX
- TYS
1 stop27h 44m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- MEX
2 stops21h 10m
Multiple Airlines
Thu 4/1611:05 am
MEX
- TYS
1 stop28h 25m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:05 pm
TYS
- MEX
1 stop8h 40m
Multiple Airlines
Wed 3/1111:10 am
MEX
- TYS
2 stops21h 34m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$569
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:10 am
TYS
- MEX
2 stops47h 40m
Multiple Airlines
Fri 7/311:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 am
TYS
- MEX
2 stops10h 40m
United Airlines
Tue 4/1411:35 am
MEX
- TYS
1 stop6h 21m
United Airlines
Deal found 2/21![United Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:30 pm
TYS
- MEX
1 stop8h 40m
Delta
Tue 12/88:20 am
MEX
- TYS
2 stops8h 53m
Delta
Deal found 2/22![Delta logo]()
$589
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:40 am
TYS
- MEX
2 stops11h 50m
Delta
Thu 4/166:55 am
MEX
- TYS
2 stops9h 19m
Delta
Deal found 2/23![Delta logo]()
$613
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:26 pm
TYS
- MEX
1 stop17h 54m
American Airlines
Sat 9/127:00 am
MEX
- TYS
1 stop14h 46m
American Airlines
Deal found 2/22![American Airlines logo]()
$636
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:05 pm
TYS
- MEX
1 stop8h 40m
Multiple Airlines
Sun 3/1511:10 am
MEX
- TYS
1 stop27h 05m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$641
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:05 pm
TYS
- MEX
1 stop8h 40m
Multiple Airlines
Sat 3/1410:20 pm
MEX
- TYS
2 stops31h 48m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$645
Best flights from Knoxville to Mexico CityDiscover carefully curated flight deals from Knoxville to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 24, 2026.
Discover carefully curated flight deals from Knoxville to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 24, 2026.
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 am
TYS
- MEX
2 stops10h 40m
United Airlines
Tue 4/1411:35 am
MEX
- TYS
1 stop6h 21m
United Airlines
Deal found 2/21![United Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:33 am
TYS
- MEX
2 stops11h 22m
Delta
Thu 4/96:55 am
MEX
- TYS
2 stops8h 50m
Delta
Deal found 2/23![Delta logo]()
$589
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:38 pm
TYS
- MEX
1 stop31h 27m
Multiple Airlines
Sun 3/110:20 pm
MEX
- TYS
2 stops19h 11m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:25 am
TYS
- MEX
2 stops11h 10m
American Airlines
Wed 3/1112:45 pm
MEX
- TYS
1 stop9h 05m
American Airlines
Deal found 2/23![American Airlines logo]()
$779
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:40 am
TYS
- MEX
1 stop6h 35m
Delta
Wed 3/117:05 am
MEX
- TYS
2 stops11h 45m
Delta
Deal found 2/21![Delta logo]()
$739
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:05 am
TYS
- MEX
1 stop6h 10m
United Airlines
Fri 3/134:45 am
MEX
- TYS
1 stop11h 25m
United Airlines
Deal found 2/22![United Airlines logo]()
$864
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:00 pm
TYS
- MEX
2 stops9h 10m
Delta
Sun 4/59:05 am
MEX
- TYS
2 stops12h 52m
Delta
Deal found 2/22![Delta logo]()
$954
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:05 am
TYS
- MEX
1 stop6h 10m
United Airlines
Sat 3/144:45 am
MEX
- TYS
1 stop11h 25m
United Airlines
Deal found 2/22![United Airlines logo]()
$954
Last-minute flights from Knoxville to Mexico CityDiscover last-minute flight deals from Knoxville to Mexico City. Data last updated February 24, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mexico City. Data last updated February 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:38 pm
TYS
- MEX
1 stop31h 27m
Multiple Airlines
Sun 3/110:20 pm
MEX
- TYS
2 stops19h 11m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$678
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:00 am
TYS
- MEX
2 stops12h 45m
Multiple Airlines
Sun 3/1511:10 am
MEX
- TYS
1 stop27h 05m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$685
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:05 pm
TYS
- MEX
1 stop8h 40m
Multiple Airlines
Wed 3/1111:10 am
MEX
- TYS
2 stops21h 34m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$569
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:05 pm
TYS
- MEX
1 stop8h 40m
Multiple Airlines
Sun 3/1511:10 am
MEX
- TYS
1 stop27h 05m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$641
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:05 pm
TYS
- MEX
1 stop8h 40m
Multiple Airlines
Sat 3/1410:20 pm
MEX
- TYS
2 stops31h 48m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:21 pm
TYS
- MEX
1 stop17h 09m
American Airlines
Wed 3/1112:45 pm
MEX
- TYS
1 stop9h 05m
American Airlines
Deal found 2/22![American Airlines logo]()
$774
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:05 am
TYS
- MEX
1 stop6h 10m
United Airlines
Thu 3/129:05 am
MEX
- TYS
1 stop8h 50m
United Airlines
Deal found 2/22![United Airlines logo]()
$734
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:40 am
TYS
- MEX
1 stop6h 35m
Delta
Wed 3/117:05 am
MEX
- TYS
2 stops11h 45m
Delta
Deal found 2/21![Delta logo]()
$739
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:25 am
TYS
- MEX
2 stops11h 10m
American Airlines
Wed 3/1112:45 pm
MEX
- TYS
1 stop9h 05m
American Airlines
Deal found 2/23![American Airlines logo]()
$779
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/92:06 pm
TYS
- MEX
1 stop7h 39m
Multiple Airlines
Wed 3/1112:40 am
MEX
- TYS
2 stops19h 44m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$712
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:55 pm
TYS
- MEX
1 stop8h 15m
United Airlines
Thu 3/128:40 am
MEX
- TYS
1 stop8h 49m
United Airlines
Deal found 2/22![United Airlines logo]()
$714
Find flight deals from Knoxville to Mexico City
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $486 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $819 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.
Fly from
Knoxville
Fly to
Mexico City
Route
Depart
Return
Price
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Tue 4/7
7:00 am-3:40 pm
2 stops10h 40m
Mexico City Benito Juarez
Tue 4/14
11:35 am-7:56 pm
1 stop6h 21m
$584
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Thu 4/2
8:33 am-5:55 pm
2 stops11h 22m
Mexico City Benito Juarez
Thu 4/9
6:55 am-5:45 pm
2 stops8h 50m
$589
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Fri 2/27
1:38 pm-8:05 pm
1 stop31h 27m
Mexico City Benito Juarez
Sun 3/1
10:20 pm-6:31 pm
2 stops19h 11m
$678
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Sun 3/8
5:40 am-10:15 am
1 stop6h 35m
Mexico City Benito Juarez
Wed 3/11
7:05 am-8:50 pm
2 stops11h 45m
$739
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Sun 3/8
9:25 am-6:35 pm
2 stops11h 10m
Mexico City Benito Juarez
Wed 3/11
12:45 pm-11:50 pm
1 stop9h 05m
$779
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Sun 3/8
7:05 am-11:15 am
1 stop6h 10m
Mexico City Benito Juarez
Fri 3/13
4:45 am-6:10 pm
1 stop11h 25m
$864
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Tue 3/3
12:00 pm-8:10 pm
2 stops9h 10m
Mexico City Benito Juarez
Sun 4/5
9:05 am-11:57 pm
2 stops12h 52m
$954
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Sun 3/8
7:05 am-11:15 am
1 stop6h 10m
Mexico City Benito Juarez
Sat 3/14
4:45 am-6:10 pm
1 stop11h 25m
$954
Compare providers for flights from Knoxville to Mexico City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Mexico City in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Knoxville-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Mexico City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Mexico City
Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.
TYS-MEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mexico City
What is the cheapest month to book a flight from Knoxville to Mexico City?
Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $597). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Mexico City?
Reviews of airlines servicing Mexico City
Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated February 24, 2026.
Read reviews from past customers who have flown Delta, Aeromexico, and United Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Mexico City?
Book flights to Mexico City if you plan to visit one of these locationsTaxco
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Mexico City flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Mexico City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Mexico City by cabin class
Find flights from Knoxville to Mexico City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Mexico City
Explore flights to Mexico City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 24, 2026.
Knoxville and Mexico City flights
Browse other Knoxville and Mexico City flight options. Last updated on February 24, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on February 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Knoxville to Mexico City
Discover the top 4 airlines that operate flights from Knoxville to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$318 | Average$582 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$455 | Average$686 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$487 | Average$660 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$548 | Average$756 | FlexibilityNo cancel fee | On-time69% |