$215+ Cheap flights from Knoxville (TYS) to Mexico City (MEX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Apr 28 — May 51
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mexico City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Mexico City
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Best
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Cheapest flights from Knoxville to Mexico CityExplore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:30 am
TYS
- MEX
2 stops15h 35m
Multiple Airlines
Mon 6/2911:05 am
MEX
- TYS
1 stop10h 29m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$477
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:30 am
TYS
- MEX
2 stops15h 35m
Multiple Airlines
Fri 7/311:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$483
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:15 am
TYS
- MEX
2 stops17h 00m
Multiple Airlines
Mon 6/2911:05 am
MEX
- TYS
1 stop10h 29m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:15 am
TYS
- MEX
2 stops17h 00m
Multiple Airlines
Fri 7/311:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:05 pm
TYS
- MEX
2 stops17h 45m
Multiple Airlines
Mon 7/1311:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:00 am
TYS
- MEX
2 stops15h 00m
Multiple Airlines
Fri 7/1011:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$523
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:27 am
TYS
- MEX
2 stops34h 18m
Multiple Airlines
Sun 5/1711:05 am
MEX
- TYS
1 stop28h 25m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- MEX
2 stops19h 35m
Multiple Airlines
Sun 4/1211:05 am
MEX
- TYS
1 stop28h 25m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$525
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:15 pm
TYS
- MEX
1 stop8h 30m
Multiple Airlines
Mon 4/276:55 pm
MEX
- TYS
2 stops37h 41m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$526
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:32 pm
TYS
- MEX
1 stop22h 58m
Multiple Airlines
Mon 6/2911:05 am
MEX
- TYS
1 stop10h 29m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$532
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:32 pm
TYS
- MEX
1 stop22h 58m
Multiple Airlines
Fri 7/311:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$538
Best flights from Knoxville to Mexico CityDiscover carefully curated flight deals from Knoxville to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 29, 2026.
Discover carefully curated flight deals from Knoxville to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:05 pm
TYS
- MEX
2 stops17h 45m
Multiple Airlines
Mon 7/1311:05 am
MEX
- TYS
1 stop10h 28m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:00 am
TYS
- MEX
2 stops10h 40m
United Airlines
Tue 5/199:35 am
MEX
- TYS
1 stop6h 36m
United Airlines
Deal found 3/28![United Airlines logo]()
$626
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:03 pm
TYS
- MEX
2 stops12h 12m
Delta
Wed 4/296:55 am
MEX
- TYS
2 stops10h 06m
Delta
Deal found 3/24![Delta logo]()
$631
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:55 am
TYS
- MEX
2 stops11h 10m
Delta
Tue 8/118:40 am
MEX
- TYS
1 stop7h 37m
Delta
Deal found 3/25![Delta logo]()
$631
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:20 am
TYS
- MEX
2 stops9h 20m
United Airlines
Tue 7/72:15 pm
MEX
- TYS
1 stop6h 57m
United Airlines
Deal found 3/25![United Airlines logo]()
$644
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:03 pm
TYS
- MEX
2 stops10h 12m
Delta
Sat 5/168:30 am
MEX
- TYS
2 stops9h 58m
Delta
Deal found 3/28![Delta logo]()
$651
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:54 pm
TYS
- MEX
1 stop7h 56m
Delta
Mon 6/291:20 pm
MEX
- TYS
1 stop8h 34m
Delta
Deal found 3/24![Delta logo]()
$661
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:40 am
TYS
- MEX
2 stops11h 50m
Delta
Mon 7/139:00 am
MEX
- TYS
2 stops12h 52m
Delta
Deal found 3/27![Delta logo]()
$666
Last-minute flights from Knoxville to Mexico CityDiscover last-minute flight deals from Knoxville to Mexico City. Data last updated March 29, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mexico City. Data last updated March 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- MEX
2 stops19h 35m
Multiple Airlines
Sun 4/1211:05 am
MEX
- TYS
1 stop28h 25m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:00 am
TYS
- MEX
1 stop6h 15m
United Airlines
Sun 4/126:30 am
MEX
- TYS
1 stop11h 26m
United Airlines
Deal found 3/26![United Airlines logo]()
$806
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:10 am
TYS
- MEX
2 stops10h 20m
Delta
Sun 4/126:55 am
MEX
- TYS
2 stops12h 56m
Delta
Deal found 3/26![Delta logo]()
$811
This Aeromexico deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:38 pm
TYS
- MEX
1 stop7h 12m
Aeromexico
Fri 4/247:05 am
MEX
- TYS
1 stop9h 09m
Aeromexico
Deal found 3/26![Aeromexico logo]()
$749
This Aeromexico deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:58 am
TYS
- MEX
1 stop11h 42m
Aeromexico
Wed 4/297:05 am
MEX
- TYS
1 stop8h 03m
Aeromexico
Deal found 3/24![Aeromexico logo]()
$626
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:03 pm
TYS
- MEX
2 stops12h 12m
Delta
Wed 4/296:55 am
MEX
- TYS
2 stops10h 06m
Delta
Deal found 3/24![Delta logo]()
$631
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:48 pm
TYS
- MEX
1 stop17h 22m
American Airlines
Wed 4/2911:20 am
MEX
- TYS
1 stop10h 36m
American Airlines
Deal found 3/26![American Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:15 pm
TYS
- MEX
1 stop8h 30m
Multiple Airlines
Mon 4/276:55 pm
MEX
- TYS
2 stops37h 41m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$526
One-way flights from Knoxville to Mexico CitySearch for one-way flight options from Knoxville to Mexico City. Find affordable one-way fares based on user searches. Data last updated March 29, 2026.
Search for one-way flight options from Knoxville to Mexico City. Find affordable one-way fares based on user searches. Data last updated March 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:24 pm
TYS
- MEX
1 stop26h 21m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:25 pm
TYS
- MEX
2 stops45h 55m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$252
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:03 pm
TYS
- MEX
1 stop9h 37m
Delta
Deal found 3/24![Delta logo]()
$395
Find flight deals from Knoxville to Mexico City
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $477 (Kiwi.com) |
One-way from | $215 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $845 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Wed 7/1
1:05 pm-4:50 am
2 stops17h 45m
Mexico City Benito Juarez
Mon 7/13
11:05 am-11:33 pm
1 stop10h 28m
$506
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Tue 5/12
7:00 am-3:40 pm
2 stops10h 40m
Mexico City Benito Juarez
Tue 5/19
9:35 am-6:11 pm
1 stop6h 36m
$626
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Wed 4/22
12:03 pm-10:15 pm
2 stops12h 12m
Mexico City Benito Juarez
Wed 4/29
6:55 am-7:01 pm
2 stops10h 06m
$631
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Tue 8/4
11:55 am-9:05 pm
2 stops11h 10m
Mexico City Benito Juarez
Tue 8/11
8:40 am-6:17 pm
1 stop7h 37m
$631
Quickest round-trip
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Wed 7/1
8:20 am-3:40 pm
2 stops9h 20m
Mexico City Benito Juarez
Tue 7/7
2:15 pm-11:12 pm
1 stop6h 57m
$644
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Wed 5/6
12:03 pm-8:15 pm
2 stops10h 12m
Mexico City Benito Juarez
Sat 5/16
8:30 am-8:28 pm
2 stops9h 58m
$651
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Thu 6/11
3:54 pm-9:50 pm
1 stop7h 56m
Mexico City Benito Juarez
Mon 6/29
1:20 pm-11:54 pm
1 stop8h 34m
$661
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Wed 7/1
5:40 am-3:30 pm
2 stops11h 50m
Mexico City Benito Juarez
Mon 7/13
9:00 am-11:52 pm
2 stops12h 52m
$666
Cheapest one-way
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Mon 5/25
7:24 pm-7:45 pm
1 stop26h 21m
$215
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Wed 4/15
4:25 pm-12:20 pm
2 stops45h 55m
$252
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Mexico City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Mexico City in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Knoxville-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Mexico City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Mexico City
Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.
TYS-MEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mexico City
Reviews of airlines servicing Mexico City
Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated March 29, 2026.
Read reviews from past customers who have flown Delta,Aeromexico, andUnited Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Mexico City?
Book flights to Mexico City if you plan to visit one of these locationsTaxco
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Complete your trip to Mexico City by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Mexico City
Explore flights to Mexico City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 29, 2026.
Knoxville and Mexico City flights
Browse other Knoxville and Mexico City flight options. Last updated on March 29, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on March 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Knoxville to Mexico City
Discover the top 4 airlines that operate flights from Knoxville to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$318 | Average$582 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$455 | Average$690 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$537 | Average$687 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$548 | Average$756 | FlexibilityNo cancel fee | On-time69% |