HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mexico City

$286+ Cheap flights from Knoxville (TYS) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Mexico City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Mexico City

Cheapest flights from Knoxville to Mexico City
Explore the most affordable flight options available from Knoxville to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:46 pmTYS - MEX
1 stop25h 19mMultiple Airlines
Thu 1/1510:00 pmMEX - TYS
2 stops36h 09mMultiple Airlines
Deal found 12/11$540
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:53 pmTYS - MEX
2 stops35h 07mMultiple Airlines
Wed 12/248:10 amMEX - TYS
1 stop30h 21mMultiple Airlines
Deal found 12/10$721
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:18 pmTYS - MEX
1 stop16h 37mAmerican Airlines
Wed 12/246:00 amMEX - TYS
1 stop8h 39mAmerican Airlines
Deal found 12/10$738
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:22 pmTYS - MEX
1 stop6h 33mAmerican Airlines
Thu 1/16:00 amMEX - TYS
1 stop10h 30mAmerican Airlines
Deal found 12/10$771
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/279:17 pmTYS - MEX
2 stops33h 28mMultiple Airlines
Sun 1/118:00 amMEX - TYS
1 stop31h 50mMultiple Airlines
Deal found 12/11$819
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:30 amTYS - MEX
1 stop12h 15mMultiple Airlines
Fri 12/1911:10 amMEX - TYS
1 stop9h 43mMultiple Airlines
Deal found 12/11$834

Find flight deals from Knoxville to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$420
(Kiwi.com)

One-way from

$286
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$846
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
Search Deals
From Knoxville McGhee Tyson to Mexico City Benito Juarez
Search Deals
One-way flight from Knoxville McGhee Tyson to Mexico City Benito Juarez
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($141 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.

Fly from

Knoxville

Fly to

Mexico City

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-7:45 pm

1 stop7h 50m

Mexico City Benito Juarez

Mon 2/2

10:00 pm-3:57 pm

2 stops40h 57m

$404

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sat 1/10

5:59 pm-9:45 pm

2 stops28h 46m

Mexico City Benito Juarez

Sat 1/17

7:00 am-8:39 am

2 stops24h 39m

$460

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 1/8

1:39 pm-10:30 pm

2 stops33h 51m

Mexico City Benito Juarez

Thu 1/15

8:10 am-7:23 pm

1 stop10h 13m

$464

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 1/26

4:06 pm-8:50 pm

1 stop5h 44m

Mexico City Benito Juarez

Mon 2/2

4:35 pm-11:45 pm

1 stop6h 10m

$505

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 12/22

4:46 pm-5:05 pm

1 stop25h 19m

Mexico City Benito Juarez

Thu 1/15

10:00 pm-11:09 am

2 stops36h 09m

$540

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Fri 2/6

7:35 am-9:10 pm

1 stop14h 35m

Mexico City Benito Juarez

Mon 2/9

6:20 am-12:10 pm

2 stops28h 50m

$551

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 1/25

9:29 am-10:45 am

2 stops26h 16m

Mexico City Benito Juarez

Sun 2/1

3:45 pm-7:56 pm

3 stops27h 11m

$553

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 12/29

6:00 am-7:45 pm

1 stop14h 45m

$286

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 12/30

6:33 pm-9:45 pm

3 stops28h 12m

$295

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 12/22

6:20 pm-9:55 am

1 stop16h 35m

$518

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Knoxville to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Mexico City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Mexico City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Mexico City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Mexico City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City

What is the cheapest month to book a flight from Knoxville to Mexico City?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Mexico City?

    A quick flight from Knoxville to Mexico City can take about 5h 44m. Aeromexico provides one of the quickest options available for as low as $505. Airlines will cover a distance of 1455 mi.

  • What are the cheapest airlines flying from Knoxville to Mexico City round-trip?

    Cheapflights users have booked flights from Knoxville to Mexico City round-trip from $318. Another airline that can offer you cheap pricing is American Airlines. Users have found that Delta is 52% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Mexico City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City.

  • Can I find deals for business class flights from Knoxville to Mexico City?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico City?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City (average of $271). Flying from Knoxville to Mexico City in December is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Taxco

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Mexico City flights
Memphis to Mexico City flights
Blountville to Mexico City flights

Top 2 airlines flying from Knoxville to Mexico City

Discover the top 2 airlines that operate flights from Knoxville to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$582FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$455Average$722FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.