$344+ Cheap flights from Mexico City (MEX) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — TYS
Oct 31 — Nov 71
Round-trip
1 adult, Economy
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Find cheap flights from Mexico City to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mexico City to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mexico City to KnoxvilleExplore the most affordable flight options available from Mexico City to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
Explore the most affordable flight options available from Mexico City to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:05 am -
2 stops49h 02m
Mon 11/21:44 pm -
1 stop23h 36m
Deal found 9/30![Multiple Airlines logo]()
$522
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:05 am -
1 stop22h 54m
Fri 10/308:00 am -
2 stops25h 05m
Deal found 9/27![Multiple Airlines logo]()
$568
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:05 am -
1 stop22h 54m
Sun 10/186:40 am -
1 stop15h 05m
Deal found 9/27![Multiple Airlines logo]()
$584
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
2 stops25h 47m
Mon 2/87:18 pm -
1 stop25h 27m
Deal found 9/26![Multiple Airlines logo]()
$589
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:35 am -
2 stops12h 42m
Tue 12/85:40 am -
2 stops10h 40m
Deal found 9/29![Delta logo]()
$603
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:10 pm -
1 stop7h 02m
Mon 2/88:47 am -
1 stop7h 28m
Deal found 9/26![Delta logo]()
$605
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:05 am -
1 stop21h 39m
Fri 10/308:00 am -
2 stops25h 05m
Deal found 9/27![Multiple Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:39 am -
1 stop7h 26m
Thu 11/196:50 am -
1 stop16h 05m
Deal found 9/27![American Airlines logo]()
$627
Best flights from Mexico City to KnoxvilleDiscover carefully curated flight deals from Mexico City to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
Discover carefully curated flight deals from Mexico City to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
2 stops25h 47m
Mon 2/87:18 pm -
1 stop25h 27m
Deal found 9/26![Multiple Airlines logo]()
$589
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:35 am -
2 stops12h 42m
Tue 12/85:40 am -
2 stops10h 40m
Deal found 9/29![Delta logo]()
$603
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:50 am -
1 stop13h 07m
Mon 2/86:15 am -
3 stops17h 15m
Deal found 9/26![United Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:45 pm -
1 stop9h 13m
Thu 11/191:51 pm -
2 stops11h 25m
Deal found 9/27![American Airlines logo]()
$648
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:10 pm -
1 stop7h 02m
Mon 2/88:47 am -
1 stop7h 28m
Deal found 9/26![Delta logo]()
$605
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:45 pm -
1 stop8h 08m
Tue 12/86:52 am -
1 stop13h 47m
Deal found 9/29![American Airlines logo]()
$674
Last-minute flights from Mexico City to KnoxvilleDiscover last-minute flight deals from Mexico City to Knoxville. Data last updated October 1, 2026 and is based on user searches.
Discover last-minute flight deals from Mexico City to Knoxville. Data last updated October 1, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:05 am -
1 stop22h 54m
Fri 10/308:00 am -
2 stops25h 05m
Deal found 9/27![Multiple Airlines logo]()
$568
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:05 am -
1 stop22h 54m
Sun 10/186:40 am -
1 stop15h 05m
Deal found 9/27![Multiple Airlines logo]()
$584
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:05 am -
1 stop22h 54m
Thu 10/297:45 am -
2 stops14h 00m
Deal found 9/27![Multiple Airlines logo]()
$728
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:05 am -
1 stop21h 39m
Fri 10/308:00 am -
2 stops25h 05m
Deal found 9/27![Multiple Airlines logo]()
$609
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:05 am -
2 stops49h 02m
Mon 11/21:44 pm -
1 stop23h 36m
Deal found 9/30![Multiple Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:39 am -
1 stop7h 26m
Thu 11/196:50 am -
1 stop16h 05m
Deal found 9/27![American Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
2 stops25h 47m
Mon 2/87:18 pm -
1 stop25h 27m
Deal found 9/26![Multiple Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:50 am -
1 stop13h 07m
Mon 2/86:15 am -
3 stops17h 15m
Deal found 9/26![United Airlines logo]()
$605
One-way flights from Mexico City to KnoxvilleSearch for one-way flight options from Mexico City to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
Search for one-way flight options from Mexico City to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1111:05 am -
1 stop22h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:20 pm -
2 stops31h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/192:55 pm -
1 stop8h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![American Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/510:55 pm -
3 stops39h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$431
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/192:40 pm -
3 stops19h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:40 am -
1 stop15h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![United Airlines logo]()
$512
Find flight deals from Mexico City to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $522 (Kiwi.com) |
One-way from | $344 (Kiwi.com) |
Popular in | June |
Cheapest in | March |
Average price | $712 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mexico City to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 1, 2026.
Use the filters below to find and compare flights from Mexico City to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Sun 10/11
11:05 am-11:14 am
1 stop22h 09m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$344
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Thu 10/15
2:25 pm-11:06 pm
3 stops30h 41m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$407
Quickest round-trip
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Fri 2/19
2:55 pm-11:59 pm
1 stop8h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$412
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Fri 2/19
2:40 pm-11:36 am
3 stops19h 56m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$448
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Thu 11/26
8:00 am-10:47 am
2 stops25h 47m
Knoxville McGhee Tyson
Mon 2/8
7:18 pm-7:45 pm
1 stop25h 27m
$589
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Wed 12/2
8:35 am-10:17 pm
2 stops12h 42m
Knoxville McGhee Tyson
Tue 12/8
5:40 am-3:20 pm
2 stops10h 40m
$603
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Thu 11/26
7:50 am-9:57 pm
1 stop13h 07m
Knoxville McGhee Tyson
Mon 2/8
6:15 am-10:30 pm
3 stops17h 15m
$605
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Thu 11/26
2:10 pm-10:12 pm
1 stop7h 02m
Knoxville McGhee Tyson
Mon 2/8
8:47 am-3:15 pm
1 stop7h 28m
$605
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Thu 11/12
1:45 pm-11:58 pm
1 stop9h 13m
Knoxville McGhee Tyson
Thu 11/19
1:51 pm-12:16 am
2 stops11h 25m
$648
Mexico CityKnoxville
MEX Mexico City Benito Juarez - TYS Knoxville McGhee Tyson
MEXTYS
Mexico City Benito Juarez
Wed 12/2
1:45 pm-10:53 pm
1 stop8h 08m
Knoxville McGhee Tyson
Tue 12/8
6:52 am-7:39 pm
1 stop13h 47m
$674
Sorted by cheapest first
Compare providers for flights from Mexico City to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Mexico City-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Mexico City-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Mexico City to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Mexico City with our price prediction graph.
MEX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Mexico City to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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