$279+ Cheap flights from St. Louis (STL) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Aug 23 — Aug 301
Round-trip
1 adult, Economy
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1. Tell us where you want to go
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Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to MedellínExplore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:35 am
STL
- MDE
1 stop12h 35m
United Airlines
Mon 9/289:45 am
MDE
- STL
1 stop12h 45m
United Airlines
Deal found 7/24![United Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:07 pm
STL
- MDE
1 stop18h 41m
American Airlines
Wed 10/286:00 am
MDE
- STL
1 stop15h 56m
American Airlines
Deal found 7/22![American Airlines logo]()
$643
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:15 am
STL
- MDE
1 stop14h 55m
United Airlines
Wed 10/289:45 am
MDE
- STL
1 stop12h 35m
United Airlines
Deal found 7/23![United Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:38 am
STL
- MDE
1 stop11h 57m
American Airlines
Sun 12/67:00 am
MDE
- STL
1 stop17h 59m
American Airlines
Deal found 7/20![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:00 am
STL
- MDE
2 stops15h 15m
American Airlines
Sat 9/126:00 am
MDE
- STL
2 stops18h 27m
American Airlines
Deal found 7/22![American Airlines logo]()
$672
Best flights from St. Louis to MedellínDiscover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:35 am
STL
- MDE
1 stop12h 35m
United Airlines
Mon 9/289:45 am
MDE
- STL
1 stop12h 45m
United Airlines
Deal found 7/21![United Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:00 am
STL
- MDE
1 stop15h 15m
American Airlines
Sat 9/126:00 am
MDE
- STL
1 stop17h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:15 am
STL
- MDE
1 stop14h 55m
United Airlines
Wed 10/289:45 am
MDE
- STL
1 stop12h 35m
United Airlines
Deal found 7/23![United Airlines logo]()
$645
Last-minute flights from St. Louis to MedellínDiscover last-minute flight deals from St. Louis to Medellín. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Medellín. Data last updated July 24, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/252:40 pm
STL
- MDE
2 stops46h 30m
Multiple Airlines
Wed 7/294:50 am
MDE
- STL
2 stops14h 36m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$914
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:18 am
STL
- MDE
1 stop18h 30m
American Airlines
Wed 8/56:00 am
MDE
- STL
1 stop16h 40m
American Airlines
Deal found 7/19![American Airlines logo]()
$875
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:40 pm
STL
- MDE
2 stops22h 30m
Multiple Airlines
Thu 8/208:50 pm
MDE
- STL
2 stops23h 34m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:35 am
STL
- MDE
1 stop12h 35m
United Airlines
Thu 8/209:45 am
MDE
- STL
1 stop24h 25m
United Airlines
Deal found 7/23![United Airlines logo]()
$763
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:35 am
STL
- MDE
1 stop8h 40m
American Airlines
Tue 9/16:00 am
MDE
- STL
1 stop16h 40m
American Airlines
Deal found 7/22![American Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:15 am
STL
- MDE
1 stop9h 55m
United Airlines
Tue 9/19:45 am
MDE
- STL
1 stop24h 25m
United Airlines
Deal found 7/23![United Airlines logo]()
$742
One-way flights from St. Louis to MedellínSearch for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:57 pm
STL
- MDE
2 stops39h 18m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:57 pm
STL
- MDE
2 stops39h 18m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:57 pm
STL
- MDE
2 stops39h 18m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:34 pm
STL
- MDE
3 stops37h 41m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- MDE
3 stops25h 21m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$371
This Avianca deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:43 am
STL
- MDE
2 stops33h 27m
Avianca
Deal found 7/21![Avianca logo]()
$407
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:07 am
STL
- MDE
2 stops13h 09m
American Airlines
Deal found 7/19![American Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:14 am
STL
- MDE
1 stop14h 56m
United Airlines
Deal found 7/21![United Airlines logo]()
$452
Find flight deals from St. Louis to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 24, 2026.
Round-trip from | $630 (United Airlines) |
|---|---|
One-way from | $279 (Kiwi.com) |
Popular in | April |
Cheapest in | June |
Average price | $705 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 9/16
8:35 am-9:10 pm
1 stop12h 35m
Medellín Jose Maria Cordova Intl
Mon 9/28
9:45 am-10:30 pm
1 stop12h 45m
$630
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 10/16
6:15 am-9:10 pm
1 stop14h 55m
Medellín Jose Maria Cordova Intl
Wed 10/28
9:45 am-10:20 pm
1 stop12h 35m
$645
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 9/6
5:00 am-8:15 pm
1 stop15h 15m
Medellín Jose Maria Cordova Intl
Sat 9/12
6:00 am-11:59 pm
1 stop17h 59m
$667
Cheapest one-way
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sat 8/8
4:57 pm-8:15 am
2 stops39h 18m
$279
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 8/4
8:43 am-6:10 pm
2 stops33h 27m
$407
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 8/2
5:18 am-11:48 pm
1 stop18h 30m
$437
Quickest one-way
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Thu 8/6
11:10 am-9:10 pm
1 stop10h 00m
$437
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sat 8/8
6:14 am-9:10 pm
1 stop14h 56m
$452
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 8/5
2:57 pm-9:10 pm
1 stop30h 13m
$456
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 8/4
5:18 am-8:16 pm
1 stop14h 58m
$512
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
STL-CO1
STL-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Medellín
STL-CO1
STL-MDE
What is the cheapest month to book a flight from St. Louis to Medellín?
Currently, June is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $438). Flying from St. Louis to Medellín in April is currently the most expensive (average of $1,064). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Medellín?
Airfare is typical for this route at the moment.
St. Louis to Medellín flights typically cost between $560 and $883 in September.The cheapest round-trip price found within the last 5 days was $630 on United Airlines (Sep 16-Sep 28).
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated July 24, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Crew
8.1
Overall
7.4
Food
6.6
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Boarding
7.7
Crew
8.1
Overall
7.4
Food
6.6
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Boarding
7.7
Crew
8.1
Overall
7.4
Food
6.6
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Medellín
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Medellín by cabin class
Find flights from St. Louis to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Medellín flights
Browse other St. Louis and Medellín flight options. Last updated on July 24, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Medellín
Discover the top 2 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$589 | Average$789 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$655 | FlexibilityNo cancel fee | On-time69% |