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$149+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$415
(FlightHub)

One-way from

$149
(FlightHub)

Popular in

December

Cheapest in

April

Average price

$784
From Lambert-St Louis to Medellín
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One-way flight from Lambert-St Louis to Medellín
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Highest demand for flights based on searches. 8% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1710:37 amSTL - MDE
1 stop13h 17mSpirit Airlines
Sat 8/2312:49 amMDE - STL
2 stops12h 43mSpirit Airlines
Deal found 7/3$349
This Avianca Connect deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/315:26 pmSTL - MDE
1 stop25h 24mMultiple Airlines
Mon 8/410:20 amMDE - STL
1 stop30h 11mMultiple Airlines
Deal found 7/1$435
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/275:26 amSTL - MDE
1 stop7h 24mAmerican Airlines
Wed 10/81:50 pmMDE - STL
1 stop10h 06mAmerican Airlines
Deal found 7/1$566
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:15 amSTL - MDE
1 stop14h 55mUnited Airlines
Wed 10/89:45 amMDE - STL
2 stops25h 04mUnited Airlines
Deal found 7/1$570
This Priceline deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/316:00 amSTL - MDE
2 stops13h 19mLATAM Airlines
Sun 8/31:38 amMDE - STL
2 stops16h 28mLATAM Airlines
Deal found 7/2$628

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 7/31

5:26 pm-1:12 pm

1 stop19h 46m

Medellín Jose Maria Cordova Intl

Mon 8/4

2:10 pm-4:31 pm

1 stop26h 21m

$415

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 7/31

5:26 pm-6:50 pm

1 stop25h 24m

Medellín Jose Maria Cordova Intl

Mon 8/4

10:20 am-4:31 pm

1 stop30h 11m

$435

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 8/27

5:26 am-12:50 pm

1 stop7h 24m

Medellín Jose Maria Cordova Intl

Wed 10/8

1:50 pm-11:56 pm

1 stop10h 06m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 8/27

6:15 am-9:10 pm

1 stop14h 55m

Medellín Jose Maria Cordova Intl

Wed 10/8

9:45 am-10:49 am

2 stops25h 04m

$570

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 7/31

6:00 am-7:19 pm

2 stops13h 19m

Medellín Jose Maria Cordova Intl

Sun 8/3

1:38 am-6:06 pm

2 stops16h 28m

$628

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 8/31

10:37 am-11:54 pm

1 stop13h 17m

$149

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 8/26

8:20 am-9:10 pm

1 stop12h 50m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest month to book a flight from St. Louis to Medellín?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $378). Flying from St. Louis to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 33% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated July 3, 2025.
Get a feel of what it's like to fly with LATAM Airlines, United Airlines, and American Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,805 reviews

Entertainment

7.0

Overall

7.5

Comfort

7.4

Crew

8.1

Boarding

7.6

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,805 reviews
LATAM Airlines
7.5
Good
1,805 reviews

Entertainment

7.0

Overall

7.5

Comfort

7.4

Crew

8.1

Boarding

7.6

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,845 reviews
LATAM Airlines
7.5
Good
1,805 reviews

Entertainment

7.0

Overall

7.5

Comfort

7.4

Crew

8.1

Boarding

7.6

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
American Airlines
7.2
Good
10,000 reviews
LATAM Airlines
7.5
Good
1,805 reviews

Entertainment

7.0

Overall

7.5

Comfort

7.4

Crew

8.1

Boarding

7.6

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Spirit Airlines
6.3
Okay
8,094 reviews
LATAM Airlines
7.5
Good
1,805 reviews

Entertainment

7.0

Overall

7.5

Comfort

7.4

Crew

8.1

Boarding

7.6

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $415, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include American Airlines and United Airlines. These flights start at 37% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Medellín?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $378). Flying from St. Louis to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$336Average$432FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$426Average$636FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$486Average$735FlexibilityNo cancel feeOn-time71%

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