$262+ Cheap flights from St. Louis (STL) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Medellín
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Best
Last-minute
One-way
Cheapest flights from St. Louis to MedellínExplore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:35 am
STL
- MDE
1 stop12h 16m
American Airlines
Fri 9/412:30 am
MDE
- STL
1 stop10h 15m
American Airlines
Deal found 5/11![American Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:10 am
STL
- MDE
1 stop10h 00m
United Airlines
Sun 9/209:45 am
MDE
- STL
1 stop12h 31m
United Airlines
Deal found 5/12![United Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:15 pm
STL
- MDE
2 stops24h 50m
United Airlines
Sat 11/710:45 am
MDE
- STL
1 stop12h 21m
United Airlines
Deal found 5/10![United Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:15 am
STL
- MDE
1 stop9h 00m
American Airlines
Mon 6/2912:30 am
MDE
- STL
1 stop10h 05m
American Airlines
Deal found 5/8![American Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:00 am
STL
- MDE
1 stop15h 15m
American Airlines
Sun 8/306:00 am
MDE
- STL
1 stop16h 40m
American Airlines
Deal found 5/10![American Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:32 am
STL
- MDE
2 stops10h 28m
American Airlines
Sun 9/205:50 am
MDE
- STL
2 stops15h 13m
American Airlines
Deal found 5/12![American Airlines logo]()
$682
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:18 am
STL
- MDE
1 stop18h 30m
American Airlines
Tue 8/46:00 am
MDE
- STL
1 stop16h 53m
American Airlines
Deal found 5/11![American Airlines logo]()
$693
Best flights from St. Louis to MedellínDiscover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:10 am
STL
- MDE
1 stop10h 00m
United Airlines
Sun 9/209:45 am
MDE
- STL
1 stop12h 31m
United Airlines
Deal found 5/10![United Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:15 am
STL
- MDE
1 stop9h 00m
American Airlines
Mon 6/2912:30 am
MDE
- STL
1 stop10h 05m
American Airlines
Deal found 5/8![American Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:15 pm
STL
- MDE
2 stops24h 50m
United Airlines
Sat 11/710:45 am
MDE
- STL
1 stop12h 21m
United Airlines
Deal found 5/10![United Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:00 am
STL
- MDE
1 stop15h 15m
American Airlines
Sat 8/2912:30 am
MDE
- STL
1 stop10h 15m
American Airlines
Deal found 5/7![American Airlines logo]()
$654
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:45 pm
STL
- MDE
2 stops26h 20m
United Airlines
Tue 11/1010:45 am
MDE
- STL
2 stops22h 52m
United Airlines
Deal found 5/11![United Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:15 am
STL
- MDE
1 stop14h 55m
United Airlines
Tue 9/19:45 am
MDE
- STL
2 stops26h 17m
United Airlines
Deal found 5/12![United Airlines logo]()
$659
Last-minute flights from St. Louis to MedellínDiscover last-minute flight deals from St. Louis to Medellín. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Medellín. Data last updated May 12, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:15 pm
STL
- MDE
2 stops20h 05m
Multiple Airlines
Thu 5/2810:30 pm
MDE
- STL
2 stops35h 57m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$735
This CheapOair deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/252:15 pm
STL
- MDE
2 stops18h 30m
Multiple Airlines
Fri 5/292:10 pm
MDE
- STL
2 stops20h 17m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
STL
- MDE
2 stops15h 10m
United Airlines
Tue 7/79:45 am
MDE
- STL
2 stops26h 26m
United Airlines
Deal found 5/11![United Airlines logo]()
$748
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:19 pm
STL
- MDE
1 stop23h 26m
Multiple Airlines
Sun 6/146:15 pm
MDE
- STL
2 stops47h 15m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$779
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:19 pm
STL
- MDE
1 stop23h 26m
Multiple Airlines
Sun 6/146:15 pm
MDE
- STL
2 stops47h 15m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$768
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:31 pm
STL
- MDE
2 stops37h 44m
Multiple Airlines
Thu 6/256:35 am
MDE
- STL
1 stop17h 14m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$760
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:16 am
STL
- MDE
1 stop14h 59m
American Airlines
Wed 6/2412:30 am
MDE
- STL
1 stop10h 05m
American Airlines
Deal found 5/10![American Airlines logo]()
$769
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:15 am
STL
- MDE
1 stop9h 00m
American Airlines
Mon 6/2912:30 am
MDE
- STL
1 stop10h 05m
American Airlines
Deal found 5/8![American Airlines logo]()
$645
One-way flights from St. Louis to MedellínSearch for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:52 pm
STL
- MDE
2 stops39h 23m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$262
This Travelocity deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:15 pm
STL
- MDE
2 stops22h 55m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$323
This Orbitz deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:05 am
STL
- MDE
2 stops37h 15m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 pm
STL
- MDE
3 stops50h 13m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
STL
- MDE
1 stop26h 46m
United Airlines
Deal found 5/10![United Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:35 am
STL
- MDE
1 stop12h 35m
United Airlines
Deal found 5/11![United Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:06 pm
STL
- MDE
3 stops35h 09m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$452
This Ovago deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
STL
- MDE
1 stop15h 10m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$481
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:05 am
STL
- MDE
2 stops24h 30m
Air Canada
Deal found 5/11![Air Canada logo]()
$489
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:30 pm
STL
- MDE
1 stop26h 40m
United Airlines
Deal found 5/11![United Airlines logo]()
$511
Find flight deals from St. Louis to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2026.
Round-trip from | $620 (American Airlines) |
|---|---|
One-way from | $262 (Kiwi.com) |
Popular in | April |
Cheapest in | September |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 9/16
11:10 am-9:10 pm
1 stop10h 00m
Medellín Jose Maria Cordova Intl
Sun 9/20
9:45 am-10:16 pm
1 stop12h 31m
$630
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 11/1
8:15 pm-10:05 pm
2 stops24h 50m
Medellín Jose Maria Cordova Intl
Sat 11/7
10:45 am-10:06 pm
1 stop12h 21m
$635
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sat 11/7
6:45 pm-10:05 pm
2 stops26h 20m
Medellín Jose Maria Cordova Intl
Tue 11/10
10:45 am-8:37 am
2 stops22h 52m
$635
Quickest round-trip
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 6/23
11:15 am-8:15 pm
1 stop9h 00m
Medellín Jose Maria Cordova Intl
Mon 6/29
12:30 am-10:35 am
1 stop10h 05m
$645
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 8/25
5:00 am-8:15 pm
1 stop15h 15m
Medellín Jose Maria Cordova Intl
Sat 8/29
12:30 am-10:45 am
1 stop10h 15m
$654
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 8/28
6:15 am-9:10 pm
1 stop14h 55m
Medellín Jose Maria Cordova Intl
Tue 9/1
9:45 am-12:02 pm
2 stops26h 17m
$659
Cheapest one-way
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Mon 7/6
4:52 pm-8:15 am
2 stops39h 23m
$262
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Mon 6/1
2:15 pm-1:10 pm
2 stops22h 55m
$323
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 5/17
7:05 am-8:20 pm
2 stops37h 15m
$328
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Mon 5/25
5:27 pm-7:40 pm
3 stops50h 13m
$392
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
STL-CO1
STL-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Medellín
STL-CO1
STL-MDE
What is the cheapest month to book a flight from St. Louis to Medellín?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $307). Flying from St. Louis to Medellín in February is currently the most expensive (average of $782). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated May 12, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Crew
8.1
Food
6.6
Entertainment
7.1
Boarding
7.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Comfort
7.3
Crew
8.1
Food
6.6
Entertainment
7.1
Boarding
7.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Comfort
7.3
Crew
8.1
Food
6.6
Entertainment
7.1
Boarding
7.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Medellín by cabin class
Find flights from St. Louis to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Medellín flights
Browse other St. Louis and Medellín flight options. Last updated on May 12, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on May 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Medellín
Discover the top 2 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$589 | Average$786 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$661 | FlexibilityNo cancel fee | On-time69% |