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Medellín

$378+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amSTL - MDE
1 stop8h 01mAmerican Airlines
Thu 1/293:10 pmMDE - STL
1 stop9h 49mAmerican Airlines
Deal found 12/26$835
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:05 amSTL - MDE
2 stops20h 37mUnited Airlines
Thu 1/2910:45 amMDE - STL
2 stops25h 17mUnited Airlines
Deal found 12/27$1,023
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:42 pmSTL - MDE
2 stops37h 13mMultiple Airlines
Fri 1/211:50 amMDE - STL
1 stop11h 43mMultiple Airlines
Deal found 12/26$1,104
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:02 pmSTL - MDE
2 stops35h 40mUnited Airlines
Thu 1/11:15 amMDE - STL
2 stops22h 28mUnited Airlines
Deal found 12/26$1,327
This Air Canada deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/284:05 pmSTL - MDE
3 stops38h 10mMultiple Airlines
Thu 1/299:45 pmMDE - STL
2 stops42h 44mMultiple Airlines
Deal found 12/26$2,973

Find flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Round-trip from

$378
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$950
From Lambert-St Louis to Medellín
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 2/10

3:49 pm-1:55 pm

1 stop21h 06m

Medellín Jose Maria Cordova Intl

Tue 2/17

2:50 pm-10:27 pm

1 stop8h 37m

$378

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 1/14

5:11 pm-1:55 pm

1 stop19h 44m

Medellín Jose Maria Cordova Intl

Mon 1/19

11:50 pm-6:51 am

2 stops32h 01m

$477

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 3/3

5:05 am-2:06 pm

1 stop8h 01m

Medellín Jose Maria Cordova Intl

Tue 3/10

12:20 am-5:40 pm

1 stop17h 20m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 2/10

9:25 am-9:10 pm

2 stops10h 45m

Medellín Jose Maria Cordova Intl

Tue 2/17

7:00 am-11:18 pm

2 stops17h 18m

$595

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Mon 4/20

7:50 am-7:50 pm

2 stops12h 00m

Medellín Jose Maria Cordova Intl

Sat 4/25

5:50 am-9:11 pm

2 stops15h 21m

$595

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 2/13

11:19 am-9:10 pm

1 stop8h 51m

Medellín Jose Maria Cordova Intl

Mon 2/23

3:10 pm-10:26 am

1 stop20h 16m

$612

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 5/23

11:00 am-9:10 pm

1 stop10h 10m

Medellín Jose Maria Cordova Intl

Fri 5/29

9:45 am-10:27 am

2 stops24h 42m

$615

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 28, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,116 reviews

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,116 reviews
United Airlines
7.4
Good
9,116 reviews

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,069 reviews
United Airlines
7.4
Good
9,116 reviews

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
Spirit Airlines
6.3
Okay
8,211 reviews
United Airlines
7.4
Good
9,116 reviews

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • How long is the flight from St. Louis to Medellín?

    American Airlines can get you from St. Louis to Medellín in just under 8h 01m. Your travel time can differ by up to . The distance between St. Louis and Medellín is about 2436 mi.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 56% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from St. Louis to Medellín

Discover the top 2 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$555Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$774FlexibilityNo cancel feeOn-time71%

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