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Medellín

$304+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Round-trip from

$304
(CheapOair)

Popular in

December

Cheapest in

April

Average price

$735
From Lambert-St Louis to Medellín
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($84 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:47 pmSTL - MDE
1 stop9h 22mSpirit Airlines
Sat 12/132:05 amMDE - STL
1 stop12h 47mSpirit Airlines
Deal found 11/4$304
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:47 pmSTL - MDE
1 stop9h 22mSpirit Airlines
Sat 12/62:05 amMDE - STL
1 stop12h 47mSpirit Airlines
Deal found 11/5$413
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:30 pmSTL - MDE
1 stop18h 25mMultiple Airlines
Thu 12/112:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 11/5$421
This Avianca Connect deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:47 pmSTL - MDE
1 stop29h 53mMultiple Airlines
Sat 12/61:00 pmMDE - STL
1 stop25h 52mMultiple Airlines
Deal found 11/5$442
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:19 pmSTL - MDE
2 stops31h 09mMultiple Airlines
Mon 12/292:25 amMDE - STL
1 stop9h 31mMultiple Airlines
Deal found 11/5$508
This Spirit deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/142:47 pmSTL - MDE
1 stop9h 22mSpirit Airlines
Wed 12/312:25 amMDE - STL
1 stop9h 31mSpirit Airlines
Deal found 11/5$526

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/10

7:43 pm-1:55 pm

2 stops17h 12m

Medellín Jose Maria Cordova Intl

Thu 1/22

2:54 pm-10:33 pm

1 stop8h 39m

$424

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 12/4

2:47 pm-9:40 pm

1 stop29h 53m

Medellín Jose Maria Cordova Intl

Sat 12/6

1:00 pm-1:52 pm

1 stop25h 52m

$442

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 1/2

10:40 am-10:55 am

1 stop23h 15m

Medellín Jose Maria Cordova Intl

Tue 1/13

6:18 am-10:37 pm

2 stops17h 19m

$474

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 4/9

6:15 am-9:10 pm

1 stop14h 55m

Medellín Jose Maria Cordova Intl

Wed 4/29

9:45 am-8:21 pm

1 stop10h 36m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Mon 4/6

11:00 am-9:10 pm

1 stop10h 10m

Medellín Jose Maria Cordova Intl

Thu 4/30

9:45 am-10:06 pm

1 stop12h 21m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 4/7

8:50 am-9:10 pm

1 stop12h 20m

Medellín Jose Maria Cordova Intl

Thu 4/30

9:45 am-8:21 pm

1 stop10h 36m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Mon 4/6

8:50 am-9:10 pm

1 stop12h 20m

Medellín Jose Maria Cordova Intl

Wed 4/29

9:45 am-8:21 pm

1 stop10h 36m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 4/8

10:30 am-9:10 pm

2 stops10h 40m

Medellín Jose Maria Cordova Intl

Thu 4/30

9:45 am-8:21 pm

1 stop10h 36m

$571

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 12/2

9:50 am-11:39 pm

2 stops12h 49m

$751

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 12/2

5:27 pm-10:05 pm

3 stops27h 38m

$1,484

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest month to book a flight from St. Louis to Medellín?

Currently, October is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $307). Flying from St. Louis to Medellín in February is currently the most expensive (average of $656). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 39% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated November 6, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,001 reviews
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,041 reviews
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
Spirit Airlines
6.3
Okay
8,114 reviews
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 56% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Medellín?

    Currently, October is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $307). Flying from St. Louis to Medellín in February is currently the most expensive (average of $656). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$307Average$347FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$554Average$655FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$770FlexibilityNo cancel feeOn-time71%

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