$194+ Cheap flights from St. Louis (STL) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Apr 24 — May 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Medellín
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to MedellínExplore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:19 pm
STL
- MDE
1 stop20h 41m
Multiple Airlines
Fri 5/151:55 pm
MDE
- STL
1 stop10h 26m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Sat 4/251:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:10 am
STL
- MDE
1 stop10h 00m
United Airlines
Tue 9/299:45 am
MDE
- STL
1 stop8h 53m
United Airlines
Deal found 3/21![United Airlines logo]()
$600
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:54 pm
STL
- MDE
1 stop16h 57m
Multiple Airlines
Sun 4/51:52 pm
MDE
- STL
2 stops21h 30m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:53 am
STL
- MDE
2 stops12h 46m
American Airlines
Thu 12/177:00 am
MDE
- STL
2 stops13h 30m
American Airlines
Deal found 3/20![American Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:06 am
STL
- MDE
1 stop9h 09m
American Airlines
Tue 5/121:53 pm
MDE
- STL
1 stop8h 31m
American Airlines
Deal found 3/21![American Airlines logo]()
$620
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:00 am
STL
- MDE
2 stops20h 05m
LATAM Airlines
Sun 9/137:00 am
MDE
- STL
2 stops25h 06m
LATAM Airlines
Deal found 3/22![LATAM Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:48 am
STL
- MDE
1 stop11h 47m
American Airlines
Tue 9/16:00 am
MDE
- STL
1 stop17h 59m
American Airlines
Deal found 3/24![American Airlines logo]()
$634
Best flights from St. Louis to MedellínDiscover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
Discover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:19 pm
STL
- MDE
1 stop20h 41m
Multiple Airlines
Fri 5/151:55 pm
MDE
- STL
1 stop10h 26m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:20 am
STL
- MDE
2 stops14h 55m
American Airlines
Fri 5/156:00 am
MDE
- STL
2 stops17h 56m
American Airlines
Deal found 3/24![American Airlines logo]()
$640
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
STL
- MDE
1 stop15h 10m
United Airlines
Thu 5/79:45 am
MDE
- STL
1 stop12h 45m
United Airlines
Deal found 3/22![United Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:29 am
STL
- MDE
2 stops13h 46m
American Airlines
Mon 4/271:50 pm
MDE
- STL
1 stop20h 26m
American Airlines
Deal found 3/24![American Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:30 pm
STL
- MDE
2 stops24h 40m
United Airlines
Thu 5/149:45 am
MDE
- STL
2 stops22h 54m
United Airlines
Deal found 3/24![United Airlines logo]()
$678
Last-minute flights from St. Louis to MedellínDiscover last-minute flight deals from St. Louis to Medellín. Data last updated March 25, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Medellín. Data last updated March 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:54 pm
STL
- MDE
1 stop16h 57m
Multiple Airlines
Sun 4/51:52 pm
MDE
- STL
2 stops21h 30m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$612
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Sat 4/251:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
STL
- MDE
2 stops14h 15m
American Airlines
Sat 4/256:00 am
MDE
- STL
2 stops17h 46m
American Airlines
Deal found 3/21![American Airlines logo]()
$654
This BusinessClass deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
STL
- MDE
2 stops17h 40m
LATAM Airlines
Mon 4/275:05 am
MDE
- STL
2 stops18h 31m
LATAM Airlines
Deal found 3/24![LATAM Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:24 am
STL
- MDE
1 stop14h 51m
American Airlines
Mon 4/271:50 pm
MDE
- STL
1 stop20h 26m
American Airlines
Deal found 3/24![American Airlines logo]()
$673
One-way flights from St. Louis to MedellínSearch for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
Search for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:19 pm
STL
- MDE
1 stop20h 41m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:59 pm
STL
- MDE
2 stops21h 46m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$244
This Avianca deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:15 pm
STL
- MDE
2 stops12h 55m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:06 am
STL
- MDE
1 stop9h 09m
American Airlines
Deal found 3/25![American Airlines logo]()
$373
Find flight deals from St. Louis to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 25, 2026.
Round-trip from | $489 (Kiwi.com) |
|---|---|
One-way from | $194 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $733 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 5/8
4:19 pm-1:00 pm
1 stop20h 41m
Medellín Jose Maria Cordova Intl
Fri 5/15
1:55 pm-12:21 am
1 stop10h 26m
$489
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 5/8
5:20 am-8:15 pm
2 stops14h 55m
Medellín Jose Maria Cordova Intl
Fri 5/15
6:00 am-11:56 pm
2 stops17h 56m
$640
Quickest round-trip
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 5/5
6:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Thu 5/7
9:45 am-10:30 pm
1 stop12h 45m
$673
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 4/24
6:29 am-8:15 pm
2 stops13h 46m
Medellín Jose Maria Cordova Intl
Mon 4/27
1:50 pm-10:16 am
1 stop20h 26m
$677
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 5/10
8:30 pm-9:10 pm
2 stops24h 40m
Medellín Jose Maria Cordova Intl
Thu 5/14
9:45 am-8:39 am
2 stops22h 54m
$678
Cheapest one-way
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Mon 5/25
4:19 pm-1:00 pm
1 stop20h 41m
$194
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 4/15
4:59 pm-2:45 pm
2 stops21h 46m
$244
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 4/26
8:15 pm-8:45 am
2 stops12h 30m
$357
Quickest one-way
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 4/26
5:24 am-12:48 pm
1 stop7h 24m
$373
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 4/15
10:09 am-9:10 pm
1 stop11h 01m
$373
Sorted by cheapest first
Best time to book a flight from St. Louis to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
STL-CO1
STL-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Medellín
STL-CO1
STL-MDE
What is the cheapest month to book a flight from St. Louis to Medellín?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $307). Flying from St. Louis to Medellín in February is currently the most expensive (average of $782). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Medellín?
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated March 25, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Food
6.6
Comfort
7.3
Entertainment
7.1
Overall
7.4
Crew
8.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Boarding
7.7
Food
6.6
Comfort
7.3
Entertainment
7.1
Overall
7.4
Crew
8.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Boarding
7.7
Food
6.6
Comfort
7.3
Entertainment
7.1
Overall
7.4
Crew
8.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Alternative routes for St. Louis to Medellín
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Medellín by cabin class
Find flights from St. Louis to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Medellín flights
Browse other St. Louis and Medellín flight options. Last updated on March 25, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on March 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Medellín
Discover the top 2 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$565 | Average$655 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$589 | Average$786 | FlexibilityNo cancel fee | On-time71% |