$125+ Cheap flights from St. Louis (STL) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Mar 7 — Mar 141
1 adult, Economy
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Find cheap flights from St. Louis to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Medellín
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One-way
Cheapest flights from St. Louis to MedellínExplore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:55 pm
STL
- MDE
1 stop17h 02m
Multiple Airlines
Tue 4/2810:52 am
MDE
- STL
2 stops19h 58m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:55 pm
STL
- MDE
1 stop17h 02m
Multiple Airlines
Sat 4/2510:52 am
MDE
- STL
1 stop12h 27m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- MDE
2 stops16h 35m
Multiple Airlines
Wed 2/252:50 pm
MDE
- STL
1 stop8h 37m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:16 pm
STL
- MDE
2 stops24h 36m
Multiple Airlines
Tue 3/2410:49 am
MDE
- STL
1 stop12h 30m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:51 pm
STL
- MDE
1 stop17h 00m
Multiple Airlines
Tue 3/241:17 am
MDE
- STL
2 stops33h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:13 pm
STL
- MDE
2 stops17h 00m
Multiple Airlines
Wed 4/2910:52 am
MDE
- STL
1 stop12h 27m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:13 pm
STL
- MDE
2 stops17h 00m
Multiple Airlines
Fri 4/2410:52 am
MDE
- STL
1 stop12h 27m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$463
Best flights from St. Louis to MedellínDiscover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 5, 2026.
Discover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:55 pm
STL
- MDE
1 stop17h 02m
Multiple Airlines
Tue 4/2810:52 am
MDE
- STL
2 stops19h 58m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$317
This CheapOair deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:30 am
STL
- MDE
2 stops28h 00m
Avianca
Tue 4/288:50 pm
MDE
- STL
2 stops35h 28m
Avianca
Deal found 2/4![Avianca logo]()
$542
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:24 am
STL
- MDE
1 stop7h 24m
American Airlines
Fri 4/241:50 pm
MDE
- STL
1 stop8h 34m
American Airlines
Deal found 2/3![American Airlines logo]()
$590
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:55 pm
STL
- MDE
1 stop17h 02m
Multiple Airlines
Sat 4/2510:52 am
MDE
- STL
1 stop12h 27m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:51 pm
STL
- MDE
1 stop17h 00m
Multiple Airlines
Tue 3/241:17 am
MDE
- STL
2 stops33h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:13 pm
STL
- MDE
2 stops17h 00m
Multiple Airlines
Wed 4/2910:52 am
MDE
- STL
1 stop12h 27m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:13 pm
STL
- MDE
2 stops17h 00m
Multiple Airlines
Fri 4/2410:52 am
MDE
- STL
1 stop12h 27m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:06 pm
STL
- MDE
2 stops41h 16m
Multiple Airlines
Sun 3/221:52 pm
MDE
- STL
1 stop17h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$535
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:55 pm
STL
- MDE
1 stop17h 02m
Multiple Airlines
Sun 5/310:52 am
MDE
- STL
2 stops27h 20m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$557
Last-minute flights from St. Louis to MedellínDiscover last-minute flight deals from St. Louis to Medellín. Data last updated February 5, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Medellín. Data last updated February 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- MDE
2 stops16h 35m
Multiple Airlines
Wed 2/252:50 pm
MDE
- STL
1 stop8h 37m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:10 am
STL
- MDE
1 stop10h 55m
United Airlines
Wed 3/119:45 am
MDE
- STL
1 stop12h 31m
United Airlines
Deal found 2/1![United Airlines logo]()
$628
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:06 pm
STL
- MDE
2 stops41h 16m
Multiple Airlines
Sun 3/221:52 pm
MDE
- STL
1 stop17h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$535
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:51 pm
STL
- MDE
1 stop17h 00m
Multiple Airlines
Tue 3/241:17 am
MDE
- STL
2 stops33h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:00 am
STL
- MDE
2 stops13h 10m
American Airlines
Wed 3/257:00 am
MDE
- STL
2 stops11h 07m
American Airlines
Deal found 2/1![American Airlines logo]()
$609
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:16 pm
STL
- MDE
2 stops24h 36m
Multiple Airlines
Tue 3/2410:49 am
MDE
- STL
1 stop12h 30m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$361
One-way flights from St. Louis to MedellínSearch for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.
Search for one-way flight options from St. Louis to Medellín. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:49 pm
STL
- MDE
1 stop21h 06m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- MDE
2 stops16h 51m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:17 pm
STL
- MDE
2 stops35h 43m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$180
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
STL
- MDE
1 stop15h 05m
United Airlines
Deal found 2/4![United Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:15 pm
STL
- MDE
2 stops24h 55m
United Airlines
Deal found 2/1![United Airlines logo]()
$379
Find flight deals from St. Louis to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 5, 2026.
Round-trip from | $317 (Kiwi.com) |
|---|---|
One-way from | $125 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $782 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.
Fly from
St. Louis
Fly to
Medellín
Route
Depart
Return
Price
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 4/21
4:55 pm-9:57 am
1 stop17h 02m
Medellín Jose Maria Cordova Intl
Tue 4/28
10:52 am-6:50 am
2 stops19h 58m
$317
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Mon 4/20
4:55 pm-9:57 am
1 stop17h 02m
Medellín Jose Maria Cordova Intl
Sat 4/25
10:52 am-11:19 pm
1 stop12h 27m
$337
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Wed 3/18
4:51 pm-9:51 am
1 stop17h 00m
Medellín Jose Maria Cordova Intl
Tue 3/24
1:17 am-10:31 am
2 stops33h 14m
$376
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 4/17
8:13 pm-1:13 pm
2 stops17h 00m
Medellín Jose Maria Cordova Intl
Wed 4/29
10:52 am-11:19 pm
1 stop12h 27m
$413
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 4/17
8:13 pm-1:13 pm
2 stops17h 00m
Medellín Jose Maria Cordova Intl
Fri 4/24
10:52 am-11:19 pm
1 stop12h 27m
$463
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 3/15
8:06 pm-1:22 pm
2 stops41h 16m
Medellín Jose Maria Cordova Intl
Sun 3/22
1:52 pm-7:02 am
1 stop17h 10m
$535
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 4/21
8:30 am-12:30 pm
2 stops28h 00m
Medellín Jose Maria Cordova Intl
Tue 4/28
8:50 pm-8:18 am
2 stops35h 28m
$542
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Thu 4/30
4:55 pm-9:57 am
1 stop17h 02m
Medellín Jose Maria Cordova Intl
Sun 5/3
10:52 am-2:12 pm
2 stops27h 20m
$557
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 4/17
5:24 am-12:48 pm
1 stop7h 24m
Medellín Jose Maria Cordova Intl
Fri 4/24
1:50 pm-10:24 pm
1 stop8h 34m
$590
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 2/24
3:49 pm-1:55 pm
1 stop21h 06m
$125
Showing 1-10 of 14 results
Best time to book a flight from St. Louis to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
STL-CO1
STL-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Medellín
STL-CO1
STL-MDE
What is the cheapest month to book a flight from St. Louis to Medellín?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $307). Flying from St. Louis to Medellín in February is currently the most expensive (average of $782). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated February 5, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Overall
7.4
Boarding
7.7
Crew
8.1
Food
6.6
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Overall
7.4
Boarding
7.7
Crew
8.1
Food
6.6
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Overall
7.4
Boarding
7.7
Crew
8.1
Food
6.6
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Medellín by cabin class
Find flights from St. Louis to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Medellín flights
Browse other St. Louis and Medellín flight options. Last updated on February 5, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on February 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Medellín
Discover the top 2 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$555 | Average$655 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$565 | Average$771 | FlexibilityNo cancel fee | On-time71% |