$644+ Cheap flights from St. Louis (STL) to Medellín
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Medellín
Cheapest
Best
Last-minute
Cheapest flights from St. Louis to MedellínExplore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:55 am -
2 stops28h 15m
Wed 11/45:35 pm -
2 stops22h 51m
Deal found 8/19![Multiple Airlines logo]()
$644
This Orbitz deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:55 am -
2 stops28h 15m
Mon 10/51:15 pm -
2 stops24h 45m
Deal found 8/18![Multiple Airlines logo]()
$663
This CheapOair deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:40 pm -
2 stops19h 10m
Wed 10/285:35 pm -
2 stops21h 51m
Deal found 8/17![Multiple Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am -
1 stop15h 15m
Wed 11/47:30 am -
1 stop9h 18m
Deal found 8/19![American Airlines logo]()
$687
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:50 pm -
2 stops26h 25m
Mon 12/211:10 am -
1 stop16h 34m
Deal found 8/17![United Airlines logo]()
$692
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:40 am -
2 stops14h 35m
Tue 12/227:30 am -
2 stops15h 52m
Deal found 8/17![American Airlines logo]()
$694
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:07 pm -
1 stop18h 41m
Wed 10/286:00 am -
1 stop15h 59m
Deal found 8/17![American Airlines logo]()
$701
This CheapOair deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:40 pm -
2 stops22h 50m
Sun 10/116:55 pm -
2 stops19h 05m
Deal found 8/20![Multiple Airlines logo]()
$715
Best flights from St. Louis to MedellínDiscover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from St. Louis to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am -
1 stop15h 15m
Wed 11/47:30 am -
1 stop9h 18m
Deal found 8/20![American Airlines logo]()
$687
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am -
1 stop14h 55m
Wed 11/410:40 am -
1 stop8h 58m
Deal found 8/19![United Airlines logo]()
$687
This LATAM Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:00 pm -
2 stops10h 35m
Mon 9/2812:00 pm -
2 stops21h 00m
Deal found 8/19![LATAM Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 am -
2 stops16h 15m
Mon 12/211:10 am -
2 stops23h 28m
Deal found 8/20![United Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:12 pm -
1 stop29h 58m
Mon 10/59:45 am -
1 stop12h 45m
Deal found 8/18![United Airlines logo]()
$718
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:30 am -
2 stops13h 40m
Wed 11/1810:40 am -
2 stops24h 52m
Deal found 8/20![United Airlines logo]()
$734
Last-minute flights from St. Louis to MedellínDiscover last-minute flight deals from St. Louis to Medellín. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Medellín. Data last updated August 21, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:40 pm -
2 stops22h 30m
Tue 9/12:10 pm -
2 stops19h 29m
Deal found 8/17![Multiple Airlines logo]()
$732
This Travelocity deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:55 am -
2 stops28h 15m
Mon 10/129:30 am -
2 stops34h 30m
Deal found 8/18![Multiple Airlines logo]()
$728
This Travelocity deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:40 pm -
2 stops20h 30m
Tue 10/131:15 pm -
2 stops24h 45m
Deal found 8/18![Multiple Airlines logo]()
$733
This LATAM Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:00 pm -
2 stops10h 35m
Mon 9/2812:00 pm -
2 stops21h 00m
Deal found 8/19![LATAM Airlines logo]()
$701
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:00 am -
1 stop15h 15m
Mon 9/286:00 am -
1 stop17h 59m
Deal found 8/19![American Airlines logo]()
$758
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
2 stops14h 15m
Sat 10/176:00 am -
1 stop15h 59m
Deal found 8/18![American Airlines logo]()
$738
This Orbitz deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:55 am -
2 stops28h 15m
Mon 10/51:15 pm -
2 stops24h 45m
Deal found 8/18![Multiple Airlines logo]()
$663
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:12 pm -
1 stop29h 58m
Mon 10/59:45 am -
1 stop12h 45m
Deal found 8/18![United Airlines logo]()
$718
Find flight deals from St. Louis to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Round-trip from | $644 (Expedia) |
|---|---|
Popular in | April |
Cheapest in | June |
Average price | $817 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Wed 10/21
5:00 am-8:15 pm
1 stop15h 15m
Medellín Jose Maria Cordova Intl
Wed 11/4
7:30 am-3:48 pm
1 stop9h 18m
$687
Quickest round-trip
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Thu 10/22
6:15 am-9:10 pm
1 stop14h 55m
Medellín Jose Maria Cordova Intl
Wed 11/4
10:40 am-6:38 pm
1 stop8h 58m
$687
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Mon 10/26
5:00 am-9:15 pm
2 stops16h 15m
Medellín Jose Maria Cordova Intl
Mon 12/21
1:10 am-11:38 pm
2 stops23h 28m
$692
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Wed 9/16
12:00 pm-10:35 pm
2 stops10h 35m
Medellín Jose Maria Cordova Intl
Mon 9/28
12:00 pm-9:00 am
2 stops21h 00m
$701
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Thu 9/24
3:12 pm-9:10 pm
1 stop29h 58m
Medellín Jose Maria Cordova Intl
Mon 10/5
9:45 am-10:30 pm
1 stop12h 45m
$718
St. LouisMedellín
STL Lambert-St Louis - MDE Medellín Jose Maria Cordova Intl
STLMDE
Lambert-St Louis
Sat 11/14
7:30 am-10:10 pm
2 stops13h 40m
Medellín Jose Maria Cordova Intl
Wed 11/18
10:40 am-10:32 am
2 stops24h 52m
$734
Sorted by cheapest first
Best time to book a flight from St. Louis to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
STL-CO1
STL-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Medellín
STL-CO1
STL-MDE
What is the cheapest month to book a flight from St. Louis to Medellín?
Currently, June is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $438). Flying from St. Louis to Medellín in April is currently the most expensive (average of $1,064). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Medellín?
Airfare is below average for this route at the moment.
St. Louis to Medellín flights typically cost between $732 and $798 in October.The cheapest round-trip price found within the last 5 days was $644 on Multiple Airlines (Oct 22-Nov 4).
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated August 21, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.7
Boarding
7.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.7
Boarding
7.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.7
Boarding
7.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
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St. Louis and Medellín flights
Browse other St. Louis and Medellín flight options. Last updated on August 21, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Medellín
Discover the top 2 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$589 | Average$817 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$655 | FlexibilityNo cancel fee | On-time69% |