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Medellín

$316+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amSTL - MDE
1 stop15h 05mUnited Airlines
Thu 1/2910:45 amMDE - STL
1 stop12h 15mUnited Airlines
Deal found 12/10$821
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:02 amSTL - MDE
2 stops14h 08mAmerican Airlines
Thu 1/297:00 amMDE - STL
2 stops14h 32mAmerican Airlines
Deal found 12/11$1,008
This Air Canada deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/284:05 pmSTL - MDE
3 stops38h 10mMultiple Airlines
Thu 1/2910:15 pmMDE - STL
2 stops42h 14mMultiple Airlines
Deal found 12/11$2,628

Find flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Round-trip from

$331
(Kiwi.com)

One-way from

$316
(Copa Airlines)

Popular in

December

Cheapest in

April

Average price

$932
From Lambert-St Louis to Medellín
Search Deals
One-way flight from Lambert-St Louis to Medellín
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Highest demand for flights based on searches. 9% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 1/28

5:42 pm-1:55 pm

1 stop19h 13m

Medellín Jose Maria Cordova Intl

Mon 2/2

10:00 pm-11:33 pm

2 stops26h 33m

$403

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 1/28

8:30 am-6:05 am

2 stops20h 35m

Medellín Jose Maria Cordova Intl

Mon 2/2

9:45 pm-7:27 pm

2 stops22h 42m

$518

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 1/8

5:11 pm-1:55 pm

1 stop19h 44m

Medellín Jose Maria Cordova Intl

Tue 1/13

2:50 pm-10:34 pm

1 stop8h 44m

$531

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 3/3

11:19 am-9:10 pm

1 stop8h 51m

Medellín Jose Maria Cordova Intl

Tue 3/10

12:20 am-2:52 pm

1 stop14h 32m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Mon 1/26

8:30 am-11:15 pm

2 stops13h 45m

Medellín Jose Maria Cordova Intl

Sat 1/31

8:10 pm-10:13 am

2 stops15h 03m

$575

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 2/13

11:19 am-9:10 pm

1 stop8h 51m

Medellín Jose Maria Cordova Intl

Mon 2/23

7:00 am-10:26 am

1 stop28h 26m

$588

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/10

9:33 am-11:39 pm

2 stops13h 06m

Medellín Jose Maria Cordova Intl

Thu 1/22

7:00 am-11:59 pm

1 stop17h 59m

$619

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/7

7:41 am-10:48 pm

2 stops14h 07m

$316

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/7

6:07 pm-1:06 pm

1 stop17h 59m

$364

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/7

4:05 pm-7:15 am

3 stops38h 10m

$1,296

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 39% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,093 reviews

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,093 reviews
United Airlines
7.4
Good
9,093 reviews

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
American Airlines
7.2
Good
11,049 reviews
United Airlines
7.4
Good
9,093 reviews

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
Spirit Airlines
6.3
Okay
8,178 reviews
United Airlines
7.4
Good
9,093 reviews

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • How long is the flight from St. Louis to Medellín?

    Avianca and American Airlines can get you from St. Louis to Medellín in just under 8h 51m. Your travel time can differ by up to 11h 44m. The distance between St. Louis and Medellín is about 2436 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 56% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$307Average$336FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$555Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$781FlexibilityNo cancel feeOn-time71%

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