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$136+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$325
(CheapOair)

One-way from

$136
(CheapOair)

Popular in

December

Cheapest in

April

Average price

$589
From Lambert-St Louis to Medellín
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One-way flight from Lambert-St Louis to Medellín
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Highest demand for flights based on searches. 10% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:57 amSTL - MDE
1 stop13h 24mSpirit Airlines
Sat 10/251:16 amMDE - STL
1 stop8h 46mSpirit Airlines
Deal found 9/15$325
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:15 pmSTL - MDE
1 stop18h 56mMultiple Airlines
Sat 11/86:59 pmMDE - STL
2 stops16h 13mMultiple Airlines
Deal found 9/17$335
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:15 pmSTL - MDE
1 stop30h 06mSpirit Airlines
Sat 11/86:59 pmMDE - STL
1 stop17h 02mSpirit Airlines
Deal found 9/17$349
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:11 amSTL - MDE
2 stops13h 10mMultiple Airlines
Sat 10/251:16 amMDE - STL
1 stop8h 46mMultiple Airlines
Deal found 9/15$386
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:12 pmSTL - MDE
1 stop22h 52mMultiple Airlines
Tue 11/1110:28 pmMDE - STL
2 stops37h 33mMultiple Airlines
Deal found 9/15$427
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:45 pmSTL - MDE
2 stops17h 10mMultiple Airlines
Sun 11/162:54 pmMDE - STL
1 stop19h 46mMultiple Airlines
Deal found 9/15$479
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:52 pmSTL - MDE
2 stops25h 23mMultiple Airlines
Wed 10/292:22 pmMDE - STL
1 stop19h 40mMultiple Airlines
Deal found 9/17$483

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 11/1

7:15 pm-2:11 pm

1 stop18h 56m

Medellín Jose Maria Cordova Intl

Sat 11/8

6:59 pm-10:12 am

2 stops16h 13m

$335

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 11/1

7:15 pm-1:21 am

1 stop30h 06m

Medellín Jose Maria Cordova Intl

Sat 11/8

6:59 pm-11:01 am

1 stop17h 02m

$349

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 10/31

2:12 pm-1:04 pm

1 stop22h 52m

Medellín Jose Maria Cordova Intl

Tue 11/11

10:28 pm-11:01 am

2 stops37h 33m

$427

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 10/24

6:42 pm-1:04 pm

1 stop18h 22m

Medellín Jose Maria Cordova Intl

Sat 10/25

1:16 am-10:02 am

1 stop8h 46m

$467

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 11/8

9:50 am-2:16 pm

3 stops27h 26m

Medellín Jose Maria Cordova Intl

Sun 11/16

6:59 pm-6:36 pm

3 stops24h 37m

$511

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 11/19

7:24 pm-8:18 am

2 stops35h 54m

Medellín Jose Maria Cordova Intl

Thu 11/27

2:54 pm-11:57 pm

1 stop10h 03m

$558

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 10/23

10:57 am-12:21 am

1 stop13h 24m

$136

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 11/20

12:20 pm-9:40 pm

1 stop8h 20m

$266

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest month to book a flight from St. Louis to Medellín?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $378). Flying from St. Louis to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 33% on airfare.

How much does it cost to fly round-trip from St. Louis to Medellín?

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
Spirit Airlines
6.3
Okay
8,023 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • How long is the flight from St. Louis to Medellín?

    Spirit Airlines can get you from St. Louis to Medellín in just under 30h 06m. Your travel time can differ by up to . The distance between St. Louis and Medellín is about 2436 mi.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 55% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Medellín?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Medellín (average of $378). Flying from St. Louis to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$307Average$427FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$554Average$661FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$578Average$771FlexibilityNo cancel feeOn-time71%

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