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Medellín

$316+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This Orbitz deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:47 pmSTL - MDE
1 stop9h 22mSpirit Airlines
Sat 12/272:25 amMDE - STL
1 stop9h 31mSpirit Airlines
Deal found 12/8$634
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/121:16 pmSTL - MDE
2 stops23h 41mMultiple Airlines
Sun 12/2811:50 amMDE - STL
1 stop22h 55mMultiple Airlines
Deal found 12/8$696
This KAYAK deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:47 pmSTL - MDE
1 stop9h 22mSpirit Airlines
Mon 12/293:10 pmMDE - STL
1 stop20h 46mSpirit Airlines
Deal found 12/8$699
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:04 pmSTL - MDE
2 stops21h 51mMultiple Airlines
Mon 12/292:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 12/8$713
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:30 pmSTL - MDE
1 stop18h 25mMultiple Airlines
Mon 12/2911:50 amMDE - STL
2 stops22h 50mMultiple Airlines
Deal found 12/8$714
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:04 pmSTL - MDE
2 stops24h 53mMultiple Airlines
Sat 12/272:25 amMDE - STL
1 stop9h 31mMultiple Airlines
Deal found 12/8$715
This Orbitz deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:51 amSTL - MDE
1 stop12h 37mSpirit Airlines
Mon 12/292:25 amMDE - STL
1 stop9h 31mSpirit Airlines
Deal found 12/9$720
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:48 amSTL - MDE
2 stops33h 52mMultiple Airlines
Mon 12/292:25 amMDE - STL
1 stop9h 31mMultiple Airlines
Deal found 12/9$764

Find flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 10, 2025.

Round-trip from

$325
(Kiwi.com)

One-way from

$316
(Copa Airlines)

Popular in

December

Cheapest in

April

Average price

$932
From Lambert-St Louis to Medellín
Search Deals
One-way flight from Lambert-St Louis to Medellín
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Mon 1/26

8:22 pm-2:15 pm

2 stops16h 53m

Medellín Jose Maria Cordova Intl

Sat 1/31

2:50 pm-11:33 pm

1 stop9h 43m

$375

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 1/28

5:42 pm-4:00 pm

1 stop21h 18m

Medellín Jose Maria Cordova Intl

Mon 2/2

10:48 pm-11:33 pm

2 stops25h 45m

$377

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 1/21

8:22 pm-1:55 pm

2 stops16h 33m

Medellín Jose Maria Cordova Intl

Wed 1/28

2:50 pm-11:33 pm

1 stop9h 43m

$409

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 1/20

5:42 pm-1:55 pm

1 stop19h 13m

Medellín Jose Maria Cordova Intl

Tue 1/27

2:50 pm-11:33 pm

1 stop9h 43m

$450

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Mon 1/19

5:11 pm-1:55 pm

1 stop19h 44m

Medellín Jose Maria Cordova Intl

Mon 1/26

10:00 pm-11:33 pm

2 stops26h 33m

$454

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 1/28

8:30 am-11:35 pm

2 stops14h 05m

Medellín Jose Maria Cordova Intl

Mon 2/2

10:45 pm-7:27 pm

2 stops21h 42m

$519

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 3/3

5:05 am-2:06 pm

1 stop8h 01m

Medellín Jose Maria Cordova Intl

Wed 3/11

7:00 am-5:40 pm

1 stop10h 40m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/7

7:41 am-10:48 pm

2 stops14h 07m

$316

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/7

6:07 pm-1:06 pm

1 stop17h 59m

$364

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/7

4:05 pm-7:15 am

3 stops38h 10m

$1,296

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 10, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 39% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 10, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,092 reviews

Food

6.6

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,092 reviews
United Airlines
7.4
Good
9,092 reviews

Food

6.6

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
American Airlines
7.2
Good
11,047 reviews
United Airlines
7.4
Good
9,092 reviews

Food

6.6

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
Spirit Airlines
6.3
Okay
8,173 reviews
United Airlines
7.4
Good
9,092 reviews

Food

6.6

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 56% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$307Average$336FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$555Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$781FlexibilityNo cancel feeOn-time71%

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