HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medellín

$294+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Medellín with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 19, 2025.

Round-trip from

$486
(Kiwi.com)

One-way from

$374
(LATAM Airlines)

Popular in

December

Cheapest in

April

Average price

$756
From Lambert-St Louis to Medellín
Search Deals
One-way flight from Lambert-St Louis to Medellín
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:47 amSTL - MDE
2 stops26h 27mMultiple Airlines
Wed 12/102:05 amMDE - STL
1 stop12h 47mMultiple Airlines
Deal found 11/19$352
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:47 amSTL - MDE
2 stops26h 27mMultiple Airlines
Fri 12/1211:50 amMDE - STL
1 stop11h 43mMultiple Airlines
Deal found 11/19$368
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:30 pmSTL - MDE
1 stop18h 25mMultiple Airlines
Thu 12/112:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 11/19$374
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:47 amSTL - MDE
2 stops26h 27mMultiple Airlines
Tue 12/1611:50 amMDE - STL
1 stop11h 43mMultiple Airlines
Deal found 11/19$383
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:47 pmSTL - MDE
1 stop9h 22mMultiple Airlines
Sat 12/133:10 pmMDE - STL
2 stops19h 37mMultiple Airlines
Deal found 11/19$389
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:43 pmSTL - MDE
2 stops17h 14mMultiple Airlines
Wed 12/172:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 11/19$391
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:30 pmSTL - MDE
1 stop18h 25mMultiple Airlines
Mon 12/1511:50 amMDE - STL
1 stop11h 43mMultiple Airlines
Deal found 11/19$396
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:04 pmSTL - MDE
2 stops21h 51mMultiple Airlines
Fri 12/122:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 11/19$397
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:30 pmSTL - MDE
1 stop18h 25mMultiple Airlines
Tue 12/1611:50 amMDE - STL
1 stop11h 43mMultiple Airlines
Deal found 11/19$409
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:47 amSTL - MDE
2 stops26h 27mMultiple Airlines
Mon 12/152:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 11/19$410

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/10

8:30 am-11:15 pm

2 stops13h 45m

Medellín Jose Maria Cordova Intl

Thu 1/22

7:55 pm-10:13 am

2 stops15h 18m

$506

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 2/13

6:00 am-10:05 pm

1 stop15h 05m

Medellín Jose Maria Cordova Intl

Mon 2/23

10:45 am-10:14 pm

1 stop12h 29m

$576

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/10

10:00 am-11:39 pm

1 stop12h 39m

Medellín Jose Maria Cordova Intl

Thu 1/22

7:00 am-5:22 pm

1 stop11h 22m

$576

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 4/2

10:09 am-9:10 pm

1 stop11h 01m

Medellín Jose Maria Cordova Intl

Tue 4/7

9:45 am-10:19 pm

1 stop12h 34m

$590

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 4/2

7:15 am-10:15 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Tue 4/7

5:50 am-9:11 pm

2 stops15h 21m

$595

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 11/25

5:30 pm-7:45 am

2 stops13h 15m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 19, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 39% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated November 19, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,019 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,019 reviews
United Airlines
7.4
Good
9,019 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,045 reviews
United Airlines
7.4
Good
9,019 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
Spirit Airlines
6.3
Okay
8,151 reviews
United Airlines
7.4
Good
9,019 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • How long is the flight from St. Louis to Medellín?

    Avianca, United Airlines, and American Airlines can get you from St. Louis to Medellín in just under 12h 39m. Your travel time can differ by up to 2h 26m. The distance between St. Louis and Medellín is about 2436 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 56% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$307Average$347FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$554Average$655FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$770FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.