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Medellín

$270+ Cheap flights from St. Louis (STL) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from St. Louis to Medellín

Cheapest flights from St. Louis to Medellín
Explore the most affordable flight options available from St. Louis to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This KAYAK deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:51 amSTL - MDE
2 stops22h 04mSpirit Airlines
Sat 12/202:25 amMDE - STL
1 stop9h 31mSpirit Airlines
Deal found 12/16$711
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:40 amSTL - MDE
2 stops14h 30mAmerican Airlines
Thu 1/297:00 amMDE - STL
2 stops17h 12mAmerican Airlines
Deal found 12/16$791
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:50 amSTL - MDE
3 stops24h 05mMultiple Airlines
Sat 12/202:25 amMDE - STL
1 stop9h 31mMultiple Airlines
Deal found 12/16$813
This Kiwi.com deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:40 amSTL - MDE
1 stop23h 15mMultiple Airlines
Wed 1/72:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 12/18$816
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:05 amSTL - MDE
2 stops23h 13mCopa Airlines
Thu 1/295:00 amMDE - STL
2 stops15h 27mCopa Airlines
Deal found 12/17$823
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amSTL - MDE
1 stop15h 05mUnited Airlines
Thu 1/2910:45 amMDE - STL
1 stop12h 15mUnited Airlines
Deal found 12/16$911
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:02 pmSTL - MDE
2 stops11h 40mUnited Airlines
Wed 1/710:45 amMDE - STL
2 stops26h 44mUnited Airlines
Deal found 12/18$1,262

Find flight deals from St. Louis to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Round-trip from

$332
(Kiwi.com)

One-way from

$270
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$950
From Lambert-St Louis to Medellín
Search Deals
One-way flight from Lambert-St Louis to Medellín
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from St. Louis to Medellín that are best for you.

Fly from

St. Louis

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/31

8:22 pm-1:55 pm

2 stops16h 33m

Medellín Jose Maria Cordova Intl

Sat 2/7

2:50 pm-11:33 pm

1 stop9h 43m

$370

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/31

8:30 am-11:15 pm

2 stops13h 45m

Medellín Jose Maria Cordova Intl

Sat 2/7

8:10 pm-10:13 am

2 stops15h 03m

$468

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 3/3

5:05 am-2:06 pm

1 stop8h 01m

Medellín Jose Maria Cordova Intl

Wed 3/11

7:00 am-5:40 pm

1 stop10h 40m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 2/26

5:05 am-9:10 pm

1 stop15h 05m

Medellín Jose Maria Cordova Intl

Fri 3/6

7:00 am-10:05 pm

1 stop16h 05m

$566

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Wed 4/1

7:45 am-9:10 pm

2 stops13h 25m

Medellín Jose Maria Cordova Intl

Thu 4/9

9:45 am-10:19 pm

1 stop12h 34m

$571

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 5/17

6:49 pm-9:10 pm

2 stops26h 21m

Medellín Jose Maria Cordova Intl

Sun 5/31

9:45 am-10:06 pm

1 stop12h 21m

$581

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 2/13

11:19 am-9:10 pm

1 stop8h 51m

Medellín Jose Maria Cordova Intl

Mon 2/23

7:00 am-10:26 am

1 stop28h 26m

$588

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 1/15

9:50 am-1:55 pm

3 stops27h 05m

$270

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/28

9:50 am-9:51 am

3 stops24h 01m

$321

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 3/28

5:00 am-10:39 pm

1 stop17h 39m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Best time to book a flight from St. Louis to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Medellín

What is the cheapest time of day to fly from STL to MDE?

Find hourly flight availability from St. Louis to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from St. Louis to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 39% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Spirit Airlines from St. Louis to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,095 reviews

Overall

7.4

Crew

8.1

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
United Airlines
7.4
Good
9,095 reviews
United Airlines
7.4
Good
9,095 reviews

Overall

7.4

Crew

8.1

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
American Airlines
7.2
Good
11,054 reviews
United Airlines
7.4
Good
9,095 reviews

Overall

7.4

Crew

8.1

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
Spirit Airlines
6.3
Okay
8,189 reviews
United Airlines
7.4
Good
9,095 reviews

Overall

7.4

Crew

8.1

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Medellín?

    Lambert-St Louis (STL) is the airport you will fly out of if you book a flight from St. Louis to Medellín. You should not have trouble finding flights to Medellín from Lambert-St Louis; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the St. Louis airport to Medellín. It is only a 12.7 mi journey to Lambert-St Louis (STL) from St. Louis’s city center.

  • How long is the flight from St. Louis to Medellín?

    Avianca and American Airlines can get you from St. Louis to Medellín in just under 8h 01m. Your travel time can differ by up to 5h 44m. The distance between St. Louis and Medellín is about 2436 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Medellín round-trip?

    Spirit Airlines, at $307, was found to be the cheapest airline from St. Louis to Medellín.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 56% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Medellín that include hotel bookings?

    Yes. In addition to deals on St. Louis to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Medellín.

  • Can I find deals for business class flights from St. Louis to Medellín?

    Yes. Cheapflights offers flight deals from St. Louis to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from St. Louis to Medellín

Discover the top 3 airlines that operate flights from St. Louis to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$307Average$336FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$555Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$781FlexibilityNo cancel feeOn-time71%

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