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McAllen

$168+ Cheap flights from Des Moines to McAllen (DSM - MFE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFE
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Des Moines to McAllen

Cheapest flights from Des Moines to McAllen
Explore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:00 am
DSM
-
MFE
1 stop7h 29m
American Airlines
Sat 4/257:32 pm
MFE
-
DSM
1 stop4h 27m
American Airlines
Deal found 3/22$311
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:04 pm
DSM
-
MFE
1 stop7h 55m
United Airlines
Sat 4/257:00 am
MFE
-
DSM
2 stops9h 15m
United Airlines
Deal found 3/22$316
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:00 am
DSM
-
MFE
2 stops9h 43m
Delta
Sat 4/255:25 am
MFE
-
DSM
2 stops10h 16m
Delta
Deal found 3/22$321
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:13 pm
DSM
-
MFE
1 stop5h 02m
American Airlines
Tue 7/281:42 pm
MFE
-
DSM
2 stops10h 17m
American Airlines
Deal found 3/19$372
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:02 pm
DSM
-
MFE
1 stop5h 18m
American Airlines
Sat 6/2010:39 am
MFE
-
DSM
1 stop5h 24m
American Airlines
Deal found 3/18$393
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/298:20 am
DSM
-
MFE
1 stop8h 04m
United Airlines
Sat 4/45:15 pm
MFE
-
DSM
1 stop5h 28m
United Airlines
Deal found 3/19$414
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:45 am
DSM
-
MFE
2 stops10h 58m
Delta
Sun 4/261:03 pm
MFE
-
DSM
2 stops9h 31m
Delta
Deal found 3/22$430
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:00 am
DSM
-
MFE
1 stop5h 02m
American Airlines
Sun 4/267:32 pm
MFE
-
DSM
1 stop4h 27m
American Airlines
Deal found 3/22$440
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/511:33 am
DSM
-
MFE
2 stops12h 26m
Delta
Sun 4/121:20 pm
MFE
-
DSM
2 stops9h 18m
Delta
Deal found 3/18$445
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:48 pm
DSM
-
MFE
1 stop7h 33m
American Airlines
Sun 6/710:39 am
MFE
-
DSM
1 stop5h 24m
American Airlines
Deal found 3/22$446

Find flight deals from Des Moines to McAllen

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$311
(American Airlines)

One-way from

$168
(American Airlines)

Popular in

May

Cheapest in

September

Average price

$394
Provider with most accurate pricing for Des Moines-McAllen Miller Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-McAllen Miller Intl flights.
Search Deals
From Des Moines to McAllen Miller Intl
Search Deals
One-way flight from Des Moines to McAllen Miller Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

3:04 pm-10:59 pm

1 stop7h 55m

McAllen Miller Intl

Sat 4/25

7:00 am-4:15 pm

2 stops9h 15m

$316

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 4/21

7:00 am-4:43 pm

2 stops9h 43m

McAllen Miller Intl

Sat 4/25

5:25 am-3:41 pm

2 stops10h 16m

$321

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 7/7

7:13 pm-12:15 am

1 stop5h 02m

McAllen Miller Intl

Tue 7/28

1:42 pm-11:59 pm

2 stops10h 17m

$372

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 6/16

7:02 pm-12:20 am

1 stop5h 18m

McAllen Miller Intl

Sat 6/20

10:39 am-4:03 pm

1 stop5h 24m

$393

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sun 4/19

5:45 am-4:43 pm

2 stops10h 58m

McAllen Miller Intl

Sun 4/26

1:03 pm-10:34 pm

2 stops9h 31m

$430

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sun 4/19

5:00 am-10:02 am

1 stop5h 02m

McAllen Miller Intl

Sun 4/26

7:32 pm-11:59 pm

1 stop4h 27m

$440

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sun 4/5

11:33 am-11:59 pm

2 stops12h 26m

McAllen Miller Intl

Sun 4/12

1:20 pm-10:38 pm

2 stops9h 18m

$445

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sun 4/5

11:17 am-6:25 pm

1 stop7h 08m

McAllen Miller Intl

Sun 4/12

7:32 pm-11:59 pm

1 stop4h 27m

$454
Quickest round-trip

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Thu 5/7

7:05 pm-11:59 pm

1 stop4h 54m

McAllen Miller Intl

Thu 5/14

7:32 pm-11:59 pm

1 stop4h 27m

$472

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sun 4/19

11:00 am-11:25 am

1 stop24h 25m

McAllen Miller Intl

Sun 4/26

7:00 pm-10:42 pm

2 stops27h 42m

$517

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Des Moines to McAllen

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to McAllen in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-McAllen flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-McAllen flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-McAllen flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-McAllen flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-McAllen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to McAllen

Have a flexible travel schedule? Discover the best time to fly to McAllen from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to McAllen

What is the cheapest month to book a flight from Des Moines to McAllen?

Currently, September is the cheapest month in which you can book a flight from Des Moines to McAllen (average of $150). Flying from Des Moines to McAllen in May is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to McAllen?

Reviews of airlines servicing McAllen

Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated March 23, 2026.
Read through reviews of airlines operating flights from Des Moines to McAllen, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,460 reviews

Overall

7.4

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,460 reviews
United Airlines
7.4
Good
9,460 reviews

Overall

7.4

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,489 reviews
United Airlines
7.4
Good
9,460 reviews

Overall

7.4

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to McAllen?

    United Airlines, Delta, and American Airlines can get you from Des Moines to McAllen in just under 5h 02m. Your travel time can differ by up to 4h 41m. Airlines will cover a distance of 1092 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to McAllen round-trip?

    Cheapflights users have booked flights from Des Moines to McAllen round-trip from $258. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Des Moines to McAllen that include hotel bookings?

    Yes. In addition to deals on Des Moines to McAllen flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to McAllen?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to McAllen.

  • Can I find deals for business class flights from Des Moines to McAllen?

    Yes. Cheapflights offers flight deals from Des Moines to McAllen by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to McAllen?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to McAllen (average of $150). Flying from Des Moines to McAllen in May is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Pharr
Weslaco
Mission
Edinburg

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Top 2 airlines flying from Des Moines to McAllen

Discover the top 2 airlines that operate flights from Des Moines to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$353FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$283Average$315FlexibilityNo cancel feeOn-time69%

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