$335+ Cheap flights from Des Moines to McAllen (DSM - MFE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFE
Nov 30 — Dec 71
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to McAllen with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to McAllen
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Cheapest flights from Des Moines to McAllenExplore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
Explore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:37 pm -
1 stop4h 38m
Thu 11/196:28 pm -
1 stop4h 55m
Deal found 10/29![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop6h 57m
Sat 11/147:00 am -
1 stop7h 20m
Deal found 10/26![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
1 stop8h 04m
Thu 11/195:00 am -
2 stops7h 31m
Deal found 10/29![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/287:43 pm -
1 stop4h 16m
Mon 1/113:59 pm -
1 stop6h 17m
Deal found 10/30![American Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:27 pm -
1 stop4h 49m
Thu 11/196:28 pm -
1 stop4h 55m
Deal found 10/29![American Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:56 pm -
1 stop7h 12m
Wed 12/95:15 pm -
1 stop5h 06m
Deal found 10/29![United Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:16 pm -
1 stop5h 13m
Sat 12/55:08 am -
2 stops8h 27m
Deal found 10/29![American Airlines logo]()
$472
Best flights from Des Moines to McAllenDiscover carefully curated flight deals from Des Moines to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
Discover carefully curated flight deals from Des Moines to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/211:42 pm -
2 stops9h 33m
Sun 1/315:15 pm -
1 stop5h 15m
Deal found 10/26![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2111:46 am -
2 stops12h 13m
Sun 1/311:29 pm -
2 stops9h 09m
Deal found 10/26![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:16 pm -
1 stop5h 13m
Sat 12/57:01 pm -
1 stop4h 29m
Deal found 10/29![American Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop6h 57m
Sat 11/147:00 am -
1 stop7h 20m
Deal found 10/26![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
1 stop8h 04m
Wed 11/185:00 am -
2 stops7h 31m
Deal found 10/30![United Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:27 pm -
2 stops8h 31m
Thu 11/195:00 am -
2 stops7h 31m
Deal found 10/29![United Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:56 pm -
1 stop7h 12m
Wed 12/95:15 pm -
1 stop5h 06m
Deal found 10/29![United Airlines logo]()
$445
Last-minute flights from Des Moines to McAllenDiscover last-minute flight deals from Des Moines to McAllen. Data last updated October 31, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to McAllen. Data last updated October 31, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:37 pm -
1 stop4h 38m
Sun 11/86:23 pm -
1 stop4h 42m
Deal found 10/30![American Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
2 stops14h 09m
Sun 11/87:00 am -
2 stops9h 07m
Deal found 10/30![United Airlines logo]()
$807
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop6h 57m
Sat 11/147:00 am -
1 stop7h 20m
Deal found 10/26![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
1 stop8h 04m
Thu 11/195:00 am -
2 stops7h 31m
Deal found 10/29![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:27 pm -
1 stop4h 49m
Thu 11/196:28 pm -
1 stop4h 55m
Deal found 10/29![American Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:37 pm -
1 stop4h 38m
Thu 11/196:28 pm -
1 stop4h 55m
Deal found 10/29![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:16 pm -
1 stop5h 13m
Sat 12/55:08 am -
2 stops8h 27m
Deal found 10/29![American Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:45 pm -
2 stops14h 09m
Sat 12/52:10 pm -
2 stops9h 05m
Deal found 10/29![United Airlines logo]()
$646
One-way flights from Des Moines to McAllenSearch for one-way flight options from Des Moines to McAllen. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
Search for one-way flight options from Des Moines to McAllen. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:50 pm -
2 stops45h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:26 pm -
1 stop24h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Allegiant Air logo]()
$369
Find flight deals from Des Moines to McAllen
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $335 (United Airlines) |
One-way from | $335 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $484 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Wed 11/25
2:50 pm-11:57 am
2 stops45h 07m
McAllen Miller Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$335
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Thu 1/21
1:42 pm-11:15 pm
2 stops9h 33m
McAllen Miller Intl
Sun 1/31
5:15 pm-10:30 pm
1 stop5h 15m
$354
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Thu 1/21
11:46 am-11:59 pm
2 stops12h 13m
McAllen Miller Intl
Sun 1/31
1:29 pm-10:38 pm
2 stops9h 09m
$359
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Wed 11/25
1:26 pm-1:27 pm
1 stop24h 01m
McAllen Miller Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$369
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Tue 11/10
3:01 pm-9:58 pm
1 stop6h 57m
McAllen Miller Intl
Sat 11/14
7:00 am-2:20 pm
1 stop7h 20m
$395
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Sat 11/14
8:00 am-4:04 pm
1 stop8h 04m
McAllen Miller Intl
Wed 11/18
5:00 am-12:31 pm
2 stops7h 31m
$400
Quickest round-trip
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Sat 11/28
7:16 pm-12:29 am
1 stop5h 13m
McAllen Miller Intl
Sat 12/5
7:01 pm-11:30 pm
1 stop4h 29m
$417
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Tue 11/10
1:27 pm-9:58 pm
2 stops8h 31m
McAllen Miller Intl
Thu 11/19
5:00 am-12:31 pm
2 stops7h 31m
$417
Des MoinesMcAllen
DSM Des Moines - MFE McAllen Miller Intl
DSMMFE
Des Moines
Sat 12/5
2:56 pm-10:08 pm
1 stop7h 12m
McAllen Miller Intl
Wed 12/9
5:15 pm-10:21 pm
1 stop5h 06m
$445
Sorted by cheapest first
Compare providers for flights from Des Moines to McAllen
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to McAllen in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-McAllen flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-McAllen flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-McAllen flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-McAllen flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-McAllen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to McAllen
Have a flexible travel schedule? Discover the best time to fly to McAllen from Des Moines with our price prediction graph.
DSM-MFE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to McAllen
What’s the top layover airport for flights from Des Moines to McAllen?
Share of 1-stop round-trip flights from Des Moines to McAllen chosen by Cheapflights users in the past 12 months, using the same layover each way.
Houston (IAH) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to McAllen on Cheapflights.
What’s the cheapest layover airport for flights from Des Moines to McAllen?
Average round-trip fare for 1-stop flights from Des Moines to McAllen, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Des Moines to McAllen?
Shortest average travel time for 1-stop one-way flights from Des Moines to McAllen, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 5h 16m.
Which airport typically offers the quickest layover for flights from Des Moines to McAllen?
Average layover duration for 1-stop one-way flights from Des Moines to McAllen, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Houston (IAH) offer the fastest connection on this route, with an average layover time of 1h 20m.
Reviews of airlines servicing McAllen
Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated October 31, 2026.
Read through reviews of airlines operating flights from Des Moines to McAllen, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Comfort
7.1
Entertainment
6.8
Overall
7.0
Boarding
7.4
Food
6.4
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Crew
7.9
Comfort
7.1
Entertainment
6.8
Overall
7.0
Boarding
7.4
Food
6.4
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from Des Moines to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near McAllen?
Book flights to McAllen if you plan to visit one of these locationsPharr
Weslaco
Edinburg
Mission
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Des Moines and McAllen flights
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Top airline flying from Des Moines to McAllen
Discover the top airline that operate flights from Des Moines to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$277 | Average$404 | FlexibilityNo cancel fee | On-time71% |