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McAllen

$138+ Cheap flights from Des Moines to McAllen (DSM - MFE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFE
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Des Moines to McAllen

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$301
(American Airlines)

One-way from

$138
(Kiwi.com)

Popular in

May

Cheapest in

November

Average price

$350
From Des Moines to McAllen Miller Intl
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One-way flight from Des Moines to McAllen Miller Intl
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Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to McAllen

Cheapest flights from Des Moines to McAllen
Explore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:00 amDSM - MFE
1 stop4h 51mAmerican Airlines
Sat 10/189:38 amMFE - DSM
1 stop5h 25mAmerican Airlines
Deal found 9/14$301
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:26 pmDSM - MFE
1 stop5h 37mAmerican Airlines
Wed 11/265:04 pmMFE - DSM
1 stop5h 49mAmerican Airlines
Deal found 9/15$305
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:00 amDSM - MFE
1 stop5h 22mAmerican Airlines
Tue 11/255:04 pmMFE - DSM
1 stop5h 49mAmerican Airlines
Deal found 9/15$340
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:26 pmDSM - MFE
1 stop5h 37mAmerican Airlines
Tue 11/252:49 pmMFE - DSM
2 stops8h 55mAmerican Airlines
Deal found 9/15$409
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/141:00 pmDSM - MFE
2 stops8h 57mUnited Airlines
Sat 10/186:55 amMFE - DSM
2 stops9h 22mUnited Airlines
Deal found 9/14$432
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:31 pmDSM - MFE
1 stop4h 28mAmerican Airlines
Tue 10/145:31 pmMFE - DSM
1 stop5h 45mAmerican Airlines
Deal found 9/16$485
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2211:32 amDSM - MFE
1 stop7h 03mAmerican Airlines
Fri 1/25:30 amMFE - DSM
1 stop5h 17mAmerican Airlines
Deal found 9/15$495
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:17 amDSM - MFE
2 stops11h 20mDelta
Tue 11/2512:44 pmMFE - DSM
2 stops8h 20mDelta
Deal found 9/15$505

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.

Fly from

Des Moines

Fly to

McAllen

Route

Depart

Return

Price

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 10/14

5:00 am-9:51 am

1 stop4h 51m

McAllen Miller Intl

Sat 10/18

9:38 am-3:03 pm

1 stop5h 25m

$301

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sat 11/22

5:26 pm-11:03 pm

1 stop5h 37m

McAllen Miller Intl

Tue 11/25

5:04 pm-10:53 pm

1 stop5h 49m

$305

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Fri 11/21

5:00 am-10:22 am

1 stop5h 22m

McAllen Miller Intl

Tue 11/25

5:04 pm-10:53 pm

1 stop5h 49m

$340

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sat 11/22

5:26 pm-11:03 pm

1 stop5h 37m

McAllen Miller Intl

Wed 11/26

5:34 am-1:22 pm

2 stops7h 48m

$409

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Tue 10/14

1:00 pm-9:57 pm

2 stops8h 57m

McAllen Miller Intl

Sat 10/18

6:55 am-4:17 pm

2 stops9h 22m

$432

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Mon 12/22

11:32 am-6:35 pm

1 stop7h 03m

McAllen Miller Intl

Fri 1/2

5:30 am-10:47 am

1 stop5h 17m

$495

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sat 11/22

6:17 am-5:37 pm

2 stops11h 20m

McAllen Miller Intl

Tue 11/25

12:44 pm-9:04 pm

2 stops8h 20m

$505

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 10/15

7:30 am-11:58 am

1 stop28h 28m

$138

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 10/15

2:37 pm-11:58 am

2 stops21h 21m

$162

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Mon 10/13

7:31 pm-11:59 pm

1 stop4h 28m

$166

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 15 results
1
2

Best time to book a flight from Des Moines to McAllen

Have a flexible travel schedule? Discover the best time to fly to McAllen from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to McAllen

What is the cheapest month to book a flight from Des Moines to McAllen?

Currently, September is the cheapest month in which you can book a flight from Des Moines to McAllen (average of $281). Flying from Des Moines to McAllen in December is currently the most expensive (average of $416). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MFE?

Find hourly flight availability from Des Moines to McAllen. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to McAllen at noon. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Des Moines to McAllen?

Reviews of airlines servicing McAllen

Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Des Moines to McAllen, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,924 reviews

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to McAllen?

    American Airlines can get you from Des Moines to McAllen in just under 4h 51m. Your travel time can differ by up to . Airlines will cover a distance of 1092 mi.

  • What are the cheapest airlines flying from Des Moines to McAllen round-trip?

    Cheapflights users have booked flights from Des Moines to McAllen round-trip from $247. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 34% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Des Moines to McAllen one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $138. Users have also found prices from $166 and $252 on American Airlines and United Airlines, respectively.

  • Can I find deals for flights from Des Moines to McAllen that include hotel bookings?

    Yes. In addition to deals on Des Moines to McAllen flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to McAllen?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to McAllen.

  • Can I find deals for business class flights from Des Moines to McAllen?

    Yes. Cheapflights offers flight deals from Des Moines to McAllen by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to McAllen?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to McAllen (average of $281). Flying from Des Moines to McAllen in December is currently the most expensive (average of $416). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Mission
Weslaco
Pharr
Edinburg

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Top 2 airlines flying from Des Moines to McAllen

Discover the top 2 airlines that operate flights from Des Moines to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$247Average$353FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$373FlexibilityNo cancel feeOn-time69%

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