HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
McAllen

$259+ Cheap flights from Des Moines to McAllen (DSM - MFE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFE
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to McAllen with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to McAllen

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(United Airlines)

Popular in

May

Cheapest in

September

Average price

$283
Provider with most accurate pricing for Des Moines-McAllen Miller Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-McAllen Miller Intl flights.
Search Deals
From Des Moines to McAllen Miller Intl
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Des Moines to McAllen

Cheapest flights from Des Moines to McAllen
Explore the most affordable flight options available from Des Moines to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:00 amDSM - MFE
1 stop5h 40mAmerican Airlines
Sun 12/74:54 pmMFE - DSM
1 stop5h 54mAmerican Airlines
Deal found 11/4$259
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:35 amDSM - MFE
2 stops10h 24mUnited Airlines
Sat 12/137:00 amMFE - DSM
1 stop7h 12mUnited Airlines
Deal found 11/6$264
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:16 pmDSM - MFE
2 stops9h 40mDelta
Sun 12/75:25 amMFE - DSM
2 stops10h 51mDelta
Deal found 11/4$269
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:00 amDSM - MFE
1 stop5h 42mAmerican Airlines
Mon 11/2411:12 amMFE - DSM
1 stop5h 29mAmerican Airlines
Deal found 11/3$284
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/193:39 pmDSM - MFE
1 stop7h 40mAmerican Airlines
Sun 11/235:34 amMFE - DSM
1 stop5h 06mAmerican Airlines
Deal found 11/4$309
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:31 pmDSM - MFE
1 stop7h 32mAmerican Airlines
Tue 11/255:34 amMFE - DSM
1 stop5h 06mAmerican Airlines
Deal found 11/5$360
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/192:52 pmDSM - MFE
1 stop7h 07mUnited Airlines
Sun 11/237:00 amMFE - DSM
2 stops9h 12mUnited Airlines
Deal found 11/4$363
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:38 pmDSM - MFE
1 stop7h 21mAmerican Airlines
Fri 12/267:16 pmMFE - DSM
1 stop4h 19mAmerican Airlines
Deal found 11/4$441

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to McAllen that are best for you.

Fly from

Des Moines

Fly to

McAllen

Route

Depart

Return

Price

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Mon 1/12

5:21 am-11:30 am

1 stop6h 09m

McAllen Miller Intl

Fri 1/23

9:59 am-3:15 pm

1 stop5h 16m

$259

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Mon 1/12

8:10 am-4:07 pm

1 stop7h 57m

McAllen Miller Intl

Wed 1/21

7:00 am-2:22 pm

1 stop7h 22m

$259

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 12/3

5:00 am-10:40 am

1 stop5h 40m

McAllen Miller Intl

Sun 12/7

4:54 pm-10:48 pm

1 stop5h 54m

$259

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sat 12/6

11:35 am-9:59 pm

2 stops10h 24m

McAllen Miller Intl

Sat 12/13

7:00 am-2:12 pm

1 stop7h 12m

$264

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Mon 11/17

5:00 am-10:42 am

1 stop5h 42m

McAllen Miller Intl

Mon 11/24

11:12 am-4:41 pm

1 stop5h 29m

$284

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Sat 12/6

5:34 am-5:43 pm

2 stops12h 09m

McAllen Miller Intl

Sat 12/13

12:49 pm-10:34 pm

2 stops9h 45m

$309

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Wed 11/19

3:39 pm-11:19 pm

1 stop7h 40m

McAllen Miller Intl

Sun 11/23

5:34 am-10:40 am

1 stop5h 06m

$309

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Mon 1/12

11:26 am-11:57 pm

2 stops12h 31m

McAllen Miller Intl

Wed 1/21

1:00 pm-10:31 pm

2 stops9h 31m

$320

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Fri 11/14

2:52 pm-8:08 pm

1 stop5h 16m

$275

Des MoinesMcAllen

DSM - MFE

DSMMFE

Des Moines

Fri 11/14

8:40 am-3:02 pm

3 stops30h 22m

$380

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Compare providers for flights from Des Moines to McAllen

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to McAllen in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-McAllen flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-McAllen flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-McAllen flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-McAllen flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-McAllen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to McAllen

Have a flexible travel schedule? Discover the best time to fly to McAllen from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to McAllen

What is the cheapest month to book a flight from Des Moines to McAllen?

Currently, September is the cheapest month in which you can book a flight from Des Moines to McAllen (average of $150). Flying from Des Moines to McAllen in May is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MFE?

Find hourly flight availability from Des Moines to McAllen. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to McAllen in the afternoon. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight at noon.

Reviews of airlines servicing McAllen

Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from Des Moines to McAllen, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,007 reviews
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,040 reviews
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Des Moines to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to McAllen?

    American Airlines and United Airlines can get you from Des Moines to McAllen in just under 6h 09m. Your travel time can differ by up to 1h 48m. Airlines will cover a distance of 1092 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to McAllen round-trip?

    Cheapflights users have booked flights from Des Moines to McAllen round-trip from $247. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Des Moines to McAllen that include hotel bookings?

    Yes. In addition to deals on Des Moines to McAllen flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to McAllen?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to McAllen.

  • Can I find deals for business class flights from Des Moines to McAllen?

    Yes. Cheapflights offers flight deals from Des Moines to McAllen by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to McAllen?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to McAllen (average of $150). Flying from Des Moines to McAllen in May is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Weslaco
Pharr
Mission
Edinburg

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to McAllen

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Dallas/Fort Worth flights
Omaha to Dallas/Fort Worth flights
Cedar Rapids to Dallas/Fort Worth flights
Des Moines to Hobby flights
Omaha to Hobby flights
Des Moines to George Bush Intcntl flights
Cedar Rapids to Hobby flights
Omaha to George Bush Intcntl flights
Omaha to Love Field flights
Moline to Dallas/Fort Worth flights
Des Moines to Love Field flights
Omaha to Austin flights
Cedar Rapids to George Bush Intcntl flights
Cedar Rapids to Austin flights
Omaha to San Antonio flights
Des Moines to San Antonio flights
Cedar Rapids to San Antonio flights
Cedar Rapids to Amarillo flights
Cedar Rapids to McAllen flights
Des Moines to Austin flights
Moline to San Antonio flights
Moline to Hobby flights
Moline to Love Field flights
Omaha to Brownsville flights
Omaha to McAllen flights
Sioux City to Dallas/Fort Worth flights
Moline to George Bush Intcntl flights
Moline to Austin flights
Des Moines to El Paso flights
Cedar Rapids to Harlingen flights
Des Moines to Harlingen flights
Omaha to Corpus Christi flights
Omaha to El Paso flights
Cedar Rapids to Love Field flights
Moline to McAllen flights
Omaha to Harlingen flights
Des Moines to Brownsville flights
Dubuque to Dallas/Fort Worth flights
Cedar Rapids to Corpus Christi flights
Waterloo to Dallas/Fort Worth flights
Des Moines to Amarillo flights
Cedar Rapids to El Paso flights
Omaha to Lubbock flights
Cedar Rapids to Brownsville flights
Cedar Rapids to Lubbock flights
Moline to El Paso flights
Moline to Corpus Christi flights
Waterloo to Hobby flights

Top 2 airlines flying from Des Moines to McAllen

Discover the top 2 airlines that operate flights from Des Moines to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$247Average$350FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$297Average$315FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.