$120+ Cheap flights from Des Moines (DSM) to Massachusetts
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BOS
Mar 5 — Mar 121
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Massachusetts with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Massachusetts
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to MassachusettsExplore the most affordable flight options available from Des Moines to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Des Moines to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:00 am
DSM
- BOS
Nonstop2h 49m
Allegiant Air
Thu 4/3011:39 am
BOS
- DSM
Nonstop3h 07m
Allegiant Air
Deal found 2/1![Allegiant Air logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:00 am
DSM
- BOS
Nonstop2h 49m
Allegiant Air
Sun 4/511:39 am
BOS
- DSM
Nonstop3h 07m
Allegiant Air
Deal found 1/31![Allegiant Air logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
DSM
- BOS
Nonstop2h 49m
Allegiant Air
Sun 5/1011:39 am
BOS
- DSM
Nonstop3h 07m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:21 pm
DSM
- BOS
1 stop23h 07m
Multiple Airlines
Sun 4/511:39 am
BOS
- DSM
Nonstop3h 07m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:30 am
DSM
- BOS
1 stop24h 41m
Multiple Airlines
Thu 4/3011:39 am
BOS
- DSM
Nonstop3h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:00 am
DSM
- BOS
Nonstop2h 49m
Multiple Airlines
Tue 4/145:49 pm
BOS
- DSM
2 stops51h 32m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$255
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:00 pm
DSM
- BOS
1 stop11h 23m
American Airlines
Wed 4/223:59 pm
BOS
- DSM
1 stop8h 50m
American Airlines
Deal found 2/3![American Airlines logo]()
$260
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
DSM
- BOS
1 stop9h 45m
American Airlines
Tue 4/146:30 am
BOS
- DSM
1 stop11h 01m
American Airlines
Deal found 2/2![American Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
DSM
- ALB
1 stop4h 42m
American Airlines
Wed 3/256:16 pm
ALB
- DSM
1 stop6h 24m
American Airlines
Deal found 1/31![American Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:21 pm
DSM
- BDL
2 stops14h 56m
Multiple Airlines
Sun 3/158:08 pm
BDL
- DSM
1 stop14h 28m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:25 pm
DSM
- ALB
1 stop4h 41m
Delta
Thu 7/26:00 am
ALB
- DSM
1 stop4h 19m
Delta
Deal found 2/2![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:25 pm
DSM
- BDL
1 stop5h 11m
Delta
Wed 8/1211:15 am
BDL
- DSM
1 stop6h 54m
Delta
Deal found 2/1![Delta logo]()
$407
Best flights from Des Moines to MassachusettsDiscover carefully curated flight deals from Des Moines to Massachusetts that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Des Moines to Massachusetts that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:21 pm
DSM
- BOS
1 stop23h 07m
Multiple Airlines
Sun 4/511:39 am
BOS
- DSM
Nonstop3h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:00 pm
DSM
- BOS
1 stop11h 23m
American Airlines
Wed 4/223:59 pm
BOS
- DSM
1 stop8h 50m
American Airlines
Deal found 2/3![American Airlines logo]()
$260
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:30 am
DSM
- BOS
1 stop7h 24m
United Airlines
Sun 3/88:15 am
BOS
- DSM
1 stop6h 08m
United Airlines
Deal found 2/2![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:20 pm
DSM
- BOS
1 stop5h 05m
Southwest
Mon 3/911:50 am
BOS
- DSM
2 stops11h 30m
Southwest
Deal found 2/2![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:30 pm
DSM
- BOS
1 stop5h 52m
Delta
Sun 5/35:35 am
BOS
- DSM
1 stop5h 19m
Delta
Deal found 2/1![Delta logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:20 pm
DSM
- ALB
1 stop16h 30m
Allegiant Air
Fri 2/207:36 pm
ALB
- DSM
1 stop22h 48m
Allegiant Air
Deal found 2/1![Allegiant Air logo]()
$429
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:37 pm
DSM
- BOS
1 stop9h 34m
American Airlines
Thu 3/2612:09 pm
BOS
- DSM
1 stop11h 25m
American Airlines
Deal found 2/2![American Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
- BOS
2 stops28h 56m
Multiple Airlines
Mon 3/96:00 am
BOS
- DSM
1 stop8h 13m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:35 am
DSM
- BOS
2 stops11h 15m
Southwest
Sun 3/85:15 am
BOS
- DSM
2 stops7h 15m
Southwest
Deal found 2/2![Southwest logo]()
$402
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:25 pm
DSM
- ALB
1 stop4h 41m
Delta
Thu 7/26:00 am
ALB
- DSM
1 stop4h 19m
Delta
Deal found 2/2![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/268:00 am
DSM
- BDL
1 stop5h 10m
United Airlines
Thu 3/56:00 am
BDL
- DSM
1 stop5h 30m
United Airlines
Deal found 2/1![United Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:45 pm
DSM
- ALB
1 stop4h 35m
Delta
Sun 4/266:00 am
ALB
- DSM
1 stop4h 54m
Delta
Deal found 2/3![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/271:41 pm
DSM
- ALB
1 stop7h 39m
American Airlines
Fri 7/38:00 am
ALB
- DSM
1 stop6h 13m
American Airlines
Deal found 2/2![American Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:15 pm
DSM
- BOS
1 stop4h 35m
Southwest
Tue 2/246:25 am
BOS
- DSM
1 stop6h 00m
Southwest
Deal found 2/2![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:25 pm
DSM
- ALB
1 stop4h 41m
Delta
Fri 7/36:00 am
ALB
- DSM
1 stop8h 22m
Delta
Deal found 2/2![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:00 am
DSM
- BDL
1 stop5h 10m
United Airlines
Mon 2/234:43 pm
BDL
- DSM
1 stop5h 58m
United Airlines
Deal found 2/2![United Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:38 pm
DSM
- BDL
1 stop7h 42m
American Airlines
Mon 3/25:24 pm
BDL
- DSM
1 stop5h 35m
American Airlines
Deal found 1/31![American Airlines logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 am
DSM
- ALB
2 stops28h 33m
Multiple Airlines
Fri 2/207:36 pm
ALB
- DSM
1 stop22h 48m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$463
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:33 am
DSM
- BDL
1 stop5h 27m
Delta
Wed 3/255:34 am
BDL
- DSM
1 stop5h 12m
Delta
Deal found 2/1![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/183:40 pm
DSM
- ALB
2 stops6h 30m
Southwest
Wed 3/256:15 pm
ALB
- DSM
1 stop4h 50m
Southwest
Deal found 1/31![Southwest logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:21 pm
DSM
- ALB
2 stops21h 10m
Multiple Airlines
Mon 3/1610:52 am
ALB
- DSM
1 stop26h 41m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$471
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/183:40 pm
DSM
- BDL
1 stop4h 30m
Southwest
Wed 3/259:05 am
BDL
- DSM
2 stops12h 45m
Southwest
Deal found 2/1![Southwest logo]()
$452
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:19 am
DSM
- BOS
1 stop5h 05m
Delta
Wed 2/251:00 pm
BOS
- DSM
1 stop7h 33m
Delta
Deal found 2/2![Delta logo]()
$412
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:30 am
DSM
- ALB
1 stop5h 01m
Delta
Sun 3/156:00 am
ALB
- DSM
1 stop4h 46m
Delta
Deal found 2/2![Delta logo]()
$427
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:15 pm
DSM
- BDL
2 stops12h 50m
Southwest
Thu 3/511:20 am
BDL
- DSM
2 stops12h 00m
Southwest
Deal found 2/1![Southwest logo]()
$492
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:10 am
DSM
- BDL
2 stops11h 25m
Southwest
Mon 3/23:10 pm
BDL
- DSM
1 stop7h 10m
Southwest
Deal found 1/31![Southwest logo]()
$492
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:47 pm
DSM
- BDL
1 stop4h 25m
Delta
Mon 3/165:34 am
BDL
- DSM
1 stop5h 12m
Delta
Deal found 2/2![Delta logo]()
$463
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:47 pm
DSM
- BDL
1 stop4h 25m
Delta
Sun 3/155:34 am
BDL
- DSM
1 stop5h 12m
Delta
Deal found 2/2![Delta logo]()
$463
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:15 pm
DSM
- ALB
1 stop8h 23m
Delta
Mon 6/156:00 am
ALB
- DSM
1 stop8h 22m
Delta
Deal found 2/1![Delta logo]()
$467
Last-minute flights from Des Moines to MassachusettsDiscover last-minute flight deals from Des Moines to Massachusetts. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Massachusetts. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:00 am
DSM
- BOS
2 stops39h 13m
Multiple Airlines
Thu 3/511:45 am
BOS
- DSM
1 stop22h 51m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
- BOS
2 stops28h 56m
Multiple Airlines
Mon 3/96:00 am
BOS
- DSM
1 stop8h 13m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:38 pm
DSM
- BOS
1 stop8h 23m
American Airlines
Mon 3/912:09 pm
BOS
- DSM
1 stop11h 25m
American Airlines
Deal found 1/31![American Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:00 am
DSM
- BOS
1 stop9h 17m
American Airlines
Sat 3/73:55 pm
BOS
- DSM
1 stop8h 45m
American Airlines
Deal found 2/2![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:04 am
DSM
- BOS
1 stop7h 01m
American Airlines
Mon 3/912:09 pm
BOS
- DSM
1 stop11h 25m
American Airlines
Deal found 2/2![American Airlines logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:27 pm
DSM
- BOS
2 stops39h 14m
Multiple Airlines
Thu 3/125:45 am
BOS
- DSM
1 stop15h 29m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:21 pm
DSM
- BDL
2 stops14h 56m
Multiple Airlines
Sun 3/158:08 pm
BDL
- DSM
1 stop14h 28m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:23 pm
DSM
- BOS
1 stop25h 05m
Multiple Airlines
Tue 3/2412:36 pm
BOS
- DSM
2 stops31h 40m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:21 pm
DSM
- BOS
2 stops14h 20m
Multiple Airlines
Wed 3/255:49 pm
BOS
- DSM
1 stop20h 40m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
DSM
- ALB
1 stop4h 42m
American Airlines
Wed 3/256:16 pm
ALB
- DSM
1 stop6h 24m
American Airlines
Deal found 1/31![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:37 pm
DSM
- BOS
1 stop9h 34m
American Airlines
Thu 3/2612:09 pm
BOS
- DSM
1 stop11h 25m
American Airlines
Deal found 2/2![American Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
DSM
- BOS
1 stop15h 29m
Multiple Airlines
Mon 3/235:49 pm
BOS
- DSM
1 stop19h 44m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$360
One-way flights from Des Moines to MassachusettsSearch for one-way flight options from Des Moines to Massachusetts. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Des Moines to Massachusetts. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
DSM
- BOS
1 stop15h 29m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/159:00 am
DSM
- BOS
2 stops48h 26m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:38 pm
DSM
- BOS
2 stops36h 48m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$137
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:00 pm
DSM
- BOS
1 stop7h 15m
American Airlines
Deal found 2/3![American Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:00 am
DSM
- BOS
3 stops54h 45m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:00 am
DSM
- BOS
2 stops9h 41m
United Airlines
Deal found 2/3![United Airlines logo]()
$174
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:20 am
DSM
- BDL
1 stop6h 55m
United Airlines
Deal found 2/1![United Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:50 pm
DSM
- BOS
2 stops39h 51m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$183
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:30 am
DSM
- ALB
1 stop7h 00m
American Airlines
Deal found 2/1![American Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:15 am
DSM
- BDL
1 stop4h 49m
Delta
Deal found 2/2![Delta logo]()
$204
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:10 pm
DSM
- BDL
2 stops9h 49m
United Airlines
Deal found 2/2![United Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
DSM
- BDL
3 stops28h 20m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$237
Find flight deals from Des Moines to Massachusetts
Keep the following information in mind while searching for Des Moines to Massachusetts flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $133 (Kiwi.com) |
One-way from | $120 (Kiwi.com) |
Popular in | February |
Cheapest in | December |
Average price | $417 |
Good round-trip deal | $174 or less |
Good one-way deal | $173 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Massachusetts that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Des Moines to Massachusetts that are best for you.
Fly from
Des Moines
Fly to
Massachusetts
Route
Depart
Return
Price
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Thu 4/2
3:21 pm-3:28 pm
1 stop23h 07m
Boston Logan Intl
Sun 4/5
11:39 am-1:46 pm
Nonstop3h 07m
$231
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Sat 4/18
12:00 pm-12:23 am
1 stop11h 23m
Boston Logan Intl
Wed 4/22
3:59 pm-11:49 pm
1 stop8h 50m
$260
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Thu 3/19
1:37 pm-12:11 am
1 stop9h 34m
Boston Logan Intl
Thu 3/26
12:09 pm-10:34 pm
1 stop11h 25m
$314
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Mon 3/2
7:17 pm-1:13 am
2 stops28h 56m
Boston Logan Intl
Mon 3/9
6:00 am-1:13 pm
1 stop8h 13m
$319
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Wed 3/4
5:30 am-1:54 pm
1 stop7h 24m
Boston Logan Intl
Sun 3/8
8:15 am-1:23 pm
1 stop6h 08m
$372
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Wed 3/4
3:20 pm-9:25 pm
1 stop5h 05m
Boston Logan Intl
Mon 3/9
11:50 am-10:20 pm
2 stops11h 30m
$377
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Thu 4/30
6:30 pm-1:22 am
1 stop5h 52m
Boston Logan Intl
Sun 5/3
5:35 am-9:54 am
1 stop5h 19m
$383
Des MoinesBoston
DSM - BOS
DSMBOS
Des Moines
Wed 3/4
8:35 am-8:50 pm
2 stops11h 15m
Boston Logan Intl
Sun 3/8
5:15 am-11:30 am
2 stops7h 15m
$402
Des MoinesAlbany
DSM - ALB
DSMALB
Des Moines
Fri 6/26
5:25 pm-11:06 pm
1 stop4h 41m
Albany Intl
Thu 7/2
6:00 am-9:19 am
1 stop4h 19m
$407
Des MoinesAlbany
DSM - ALB
DSMALB
Des Moines
Fri 4/24
5:45 pm-11:20 pm
1 stop4h 35m
Albany Intl
Sun 4/26
6:00 am-9:54 am
1 stop4h 54m
$407
Showing 1-10 of 52 results
Best time to book a flight from Des Moines to Massachusetts
Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Des Moines with our price prediction graph.
DSM-BOS
DSM-ALB
DSM-BDL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Massachusetts
DSM-USMA
DSM-BOS
DSM-ALB
DSM-BDL
What is the cheapest month to book a flight from Des Moines to Massachusetts?
Currently, December is the cheapest month in which you can book a flight from Des Moines to Massachusetts (average of $95). Flying from Des Moines to Massachusetts in February is currently the most expensive (average of $341). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Massachusetts
Get insights into the airlines that provide service to Massachusetts. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Massachusetts. Reviews last updated February 3, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Massachusetts. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Massachusetts. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Des Moines to Massachusetts
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Massachusetts by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Massachusetts by cabin class
Find flights from Des Moines to Massachusetts, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Massachusetts flights
Browse other Des Moines and Massachusetts flight options. Last updated on February 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Massachusetts flights
Consider these flights traveling from Des Moines to Massachusetts.
Top 5 airlines flying from Des Moines to Massachusetts
Discover the top 5 airlines that operate flights from Des Moines to Massachusetts. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$96 | Average$168 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$165 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$426 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$259 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$291 | Average$432 | FlexibilityNo cancel fee | On-time69% |