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$517+ Cheap flights from Florence, SC to Manchester, NH (FLO - MHT)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MHT
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Florence to Manchester

Cheapest flights from Florence to Manchester
Explore the most affordable flight options available from Florence to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:16 am
FLO
-
MHT
2 stops11h 16m
American Airlines
Tue 3/316:00 am
MHT
-
FLO
2 stops17h 08m
American Airlines
Deal found 3/12$517

Find flight deals from Florence to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.

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FlightHub
3 stars

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FlightHub
3 stars

Round-trip from

$517
(American Airlines)
Provider with most accurate pricing for Florence-Boston Logan Intl flight deals.
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Provider most trusted by Cheapflights users for Florence-Boston Logan Intl flights.
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From Florence to Manchester
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Florence to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceManchester

FLO - MHT

FLOMHT

Florence

Fri 3/27

5:16 am-4:32 pm

2 stops11h 16m

Manchester

Tue 3/31

6:00 am-11:08 pm

2 stops17h 08m

$517

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Sorted by cheapest first

Best time to book a flight from Florence to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Manchester

What is the cheapest month to book a flight from Florence, South Carolina to Manchester, New Hampshire?

Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to Manchester, New Hampshire (average of $50). Flying from Florence, South Carolina to Manchester, New Hampshire in February is currently the most expensive (average of $97). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Manchester, New Hampshire?

    A quick flight from Florence, South Carolina to Manchester, New Hampshire can take about 11h 16m. American Airlines provides one of the quickest options available for as low as $517. The distance from Florence, South Carolina to Manchester, New Hampshire is about 751 mi.

  • Can I find deals for flights from Florence to Manchester that include hotel bookings?

    Yes. In addition to deals on Florence to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Manchester.

  • Can I find deals for business class flights from Florence to Manchester?

    Yes. Cheapflights offers flight deals from Florence to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Manchester, New Hampshire?

    Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to Manchester, New Hampshire (average of $50). Flying from Florence, South Carolina to Manchester, New Hampshire in February is currently the most expensive (average of $97). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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