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$125+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/171:37 pmDSM - MSY
1 stop6h 17mMultiple Airlines
Fri 11/212:12 pmMSY - DSM
1 stop24h 13mMultiple Airlines
Deal found 11/1$217
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1610:50 amDSM - MSY
1 stop21h 45mMultiple Airlines
Thu 11/2011:12 amMSY - DSM
1 stop10h 02mMultiple Airlines
Deal found 11/1$218
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:38 pmDSM - AEX
1 stop7h 18mAmerican Airlines
Mon 12/86:00 amAEX - DSM
1 stop4h 28mAmerican Airlines
Deal found 11/1$238
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:17 amDSM - AEX
2 stops9h 57mDelta
Mon 12/86:05 amAEX - DSM
1 stop7h 26mDelta
Deal found 11/1$244
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/209:19 amDSM - MSY
1 stop7h 49mMultiple Airlines
Mon 11/247:24 pmMSY - DSM
1 stop28h 00mMultiple Airlines
Deal found 11/2$300
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:39 pmDSM - BTR
1 stop7h 16mAmerican Airlines
Wed 11/1910:23 amBTR - DSM
1 stop6h 28mAmerican Airlines
Deal found 11/2$309
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:21 amDSM - MSY
1 stop5h 39mAmerican Airlines
Wed 12/2410:27 amMSY - DSM
1 stop6h 34mAmerican Airlines
Deal found 11/2$312
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:05 amDSM - BTR
1 stop5h 13mUnited Airlines
Wed 11/195:07 amBTR - DSM
2 stops9h 12mUnited Airlines
Deal found 11/2$314
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:18 pmDSM - MSY
1 stop5h 57mAmerican Airlines
Tue 12/235:30 amMSY - DSM
1 stop5h 17mAmerican Airlines
Deal found 11/1$316
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:34 amDSM - MSY
1 stop5h 24mDelta
Sat 12/66:35 amMSY - DSM
1 stop7h 37mDelta
Deal found 11/1$317
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:00 amDSM - BTR
1 stop4h 49mAmerican Airlines
Tue 12/235:32 amBTR - DSM
1 stop5h 15mAmerican Airlines
Deal found 11/1$326
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:35 amDSM - MSY
2 stops7h 38mAmerican Airlines
Sat 12/63:56 pmMSY - DSM
2 stops7h 49mAmerican Airlines
Deal found 11/1$327

Cheap flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$217
(Kiwi.com)

One-way from

$125
(United Airlines)

Popular in

May

Cheapest in

November

Average price

$361
Provider with most accurate pricing for Des Moines-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-New Orleans Louis Armstrong flights.
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From Des Moines to Louisiana
Search Deals
One-way flight from Des Moines to Louisiana
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Des Moines

Fly to

Louisiana

Route

Depart

Return

Price

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sun 11/16

10:50 am-8:35 am

1 stop21h 45m

New Orleans Louis Armstrong

Thu 11/20

11:12 am-9:14 pm

1 stop10h 02m

$218

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Fri 12/5

6:17 am-4:14 pm

2 stops9h 57m

Alexandria

Mon 12/8

6:05 am-1:31 pm

1 stop7h 26m

$244

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Thu 11/20

9:19 am-5:08 pm

1 stop7h 49m

New Orleans Louis Armstrong

Mon 11/24

7:24 pm-11:24 pm

1 stop28h 00m

$300

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sun 2/15

5:24 am-12:12 pm

1 stop6h 48m

New Orleans Louis Armstrong

Sat 2/21

11:42 am-4:59 pm

1 stop5h 17m

$313

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 1/17

1:03 pm-7:52 pm

1 stop6h 49m

New Orleans Louis Armstrong

Sat 1/24

7:30 am-12:17 pm

1 stop4h 47m

$315

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 12/3

5:34 am-10:58 am

1 stop5h 24m

New Orleans Louis Armstrong

Sat 12/6

6:35 am-2:12 pm

1 stop7h 37m

$317

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Fri 11/14

1:05 pm-10:44 pm

2 stops9h 39m

Baton Rouge Ryan

Wed 11/19

5:07 am-2:19 pm

2 stops9h 12m

$319

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 1/17

5:51 pm-10:59 pm

1 stop5h 08m

New Orleans Louis Armstrong

Sat 1/24

7:21 am-4:24 pm

2 stops9h 03m

$320

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Tue 3/24

11:04 am-4:01 pm

1 stop4h 57m

Alexandria

Sat 3/28

5:00 pm-10:28 pm

1 stop5h 28m

$323

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 12/16

5:00 am-9:49 am

1 stop4h 49m

Baton Rouge Ryan

Tue 12/23

5:32 am-10:47 am

1 stop5h 15m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 28 results
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Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LA?

Find hourly flight availability from Des Moines to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

When flying from Des Moines to Louisiana, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 41% versus a flight in the morning.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated November 3, 2025.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,997 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,034 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 4h 49m. The distance between Des Moines and Louisiana is about 773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Louisiana one-way?

    One-way options have recently been found by users for as low as $125 on United Airlines. Other airlines that offer cheap prices include American Airlines from $239 and Delta from $254 one-way.

  • What are the most popular routes from Des Moines to Louisiana?

    Most travelers choose Des Moines - New Orleans Louis Armstrong, Des Moines - Alexandria or Des Moines - Baton Rouge Ryan when deciding on the best route from Des Moines to Louisiana.

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$416FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$405FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$278Average$406FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$331Average$429FlexibilityNo cancel feeOn-time69%

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