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$133+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:25 pmDSM - MSY
1 stop28h 25mMultiple Airlines
Mon 12/151:41 pmMSY - DSM
1 stop27h 21mMultiple Airlines
Deal found 11/16$227
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:53 pmDSM - MSY
1 stop23h 26mMultiple Airlines
Fri 12/51:41 pmMSY - DSM
1 stop28h 21mMultiple Airlines
Deal found 11/16$231
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:31 amDSM - MSY
2 stops36h 11mMultiple Airlines
Thu 12/113:20 pmMSY - DSM
1 stop7h 01mMultiple Airlines
Deal found 11/16$244
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:45 pmDSM - MSY
1 stop17h 02mMultiple Airlines
Tue 1/65:05 pmMSY - DSM
2 stops46h 35mMultiple Airlines
Deal found 11/14$279
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:00 amDSM - MSY
2 stops46h 09mAllegiant Air
Mon 12/151:41 pmMSY - DSM
1 stop27h 21mAllegiant Air
Deal found 11/15$300
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:53 pmDSM - MSY
1 stop6h 46mUnited Airlines
Tue 12/92:29 pmMSY - DSM
1 stop7h 08mUnited Airlines
Deal found 11/16$317
This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:17 pmDSM - AEX
1 stop6h 44mDelta
Sun 11/235:00 pmAEX - DSM
1 stop5h 33mDelta
Deal found 11/15$343
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:26 pmDSM - AEX
1 stop5h 16mAmerican Airlines
Sat 11/296:18 pmAEX - DSM
1 stop4h 35mAmerican Airlines
Deal found 11/15$577
This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:18 pmDSM - AEX
1 stop6h 17mDelta
Tue 1/66:00 amAEX - DSM
1 stop4h 41mDelta
Deal found 11/15$628

Cheap flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$227
(Kiwi.com)

One-way from

$133
(Mytrip)

Popular in

February

Cheapest in

November

Average price

$357
Provider with most accurate pricing for Des Moines-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-New Orleans Louis Armstrong flights.
Search Deals
From Des Moines to Louisiana
Search Deals
One-way flight from Des Moines to Louisiana
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Des Moines

Fly to

Louisiana

Route

Depart

Return

Price

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 12/8

9:31 am-9:42 pm

2 stops36h 11m

New Orleans Louis Armstrong

Thu 12/11

3:20 pm-10:21 pm

1 stop7h 01m

$244

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 12/10

1:25 pm-9:42 pm

2 stops32h 17m

New Orleans Louis Armstrong

Mon 12/15

1:41 pm-5:02 pm

1 stop27h 21m

$257

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Fri 1/23

11:09 am-10:58 pm

2 stops11h 49m

New Orleans Louis Armstrong

Sun 2/1

6:15 am-9:21 pm

3 stops39h 06m

$288

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sun 2/15

5:24 am-10:17 am

1 stop4h 53m

New Orleans Louis Armstrong

Sat 2/21

2:04 pm-9:19 pm

1 stop7h 15m

$313

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 2/21

1:02 pm-8:07 pm

1 stop7h 05m

New Orleans Louis Armstrong

Sat 2/28

6:30 am-12:17 pm

1 stop5h 47m

$315

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 1/17

1:03 pm-5:52 pm

1 stop4h 49m

New Orleans Louis Armstrong

Sat 1/24

4:21 pm-9:24 pm

1 stop5h 03m

$315

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 12/6

2:53 pm-9:39 pm

1 stop6h 46m

New Orleans Louis Armstrong

Tue 12/9

2:29 pm-9:37 pm

1 stop7h 08m

$317

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 2/21

5:10 am-11:35 am

1 stop6h 25m

New Orleans Louis Armstrong

Sat 2/28

8:25 am-7:15 pm

2 stops10h 50m

$320

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Thu 2/5

2:58 pm-8:21 am

1 stop17h 23m

New Orleans Louis Armstrong

Mon 2/9

6:55 pm-10:46 am

2 stops39h 51m

$321

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Fri 11/21

2:17 pm-9:01 pm

1 stop6h 44m

Alexandria

Sun 11/23

5:00 pm-10:33 pm

1 stop5h 33m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 20 results
1
2

Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in May is currently the most expensive (average of $332). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LA?

Find hourly flight availability from Des Moines to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

When flying from Des Moines to Louisiana, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 41% versus a flight in the morning.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated November 17, 2025.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,244 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,015 reviews
Southwest
8.0
Very good
4,244 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,050 reviews
Southwest
8.0
Very good
4,244 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 4h 53m. The distance between Des Moines and Louisiana is about 820 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Des Moines to Louisiana?

    Most travelers choose Des Moines - New Orleans Louis Armstrong, Des Moines - Baton Rouge Ryan or Des Moines - Alexandria when deciding on the best route from Des Moines to Louisiana.

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in May is currently the most expensive (average of $332). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

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Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$418FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$407FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$278Average$413FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$331Average$423FlexibilityNo cancel feeOn-time69%

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