$149+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Nov 13 — Nov 201
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2026.
This Frontier deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop13h 42m
Thu 12/32:17 pm -
1 stop5h 23m
Deal found 10/13![Frontier logo]()
$266
This CheapOair deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:35 pm -
1 stop13h 28m
Thu 12/3110:58 am -
1 stop8h 41m
Deal found 10/11![Frontier logo]()
$286
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm -
1 stop7h 20m
Mon 12/146:00 am -
1 stop8h 15m
Deal found 10/13![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:25 pm -
2 stops7h 10m
Tue 12/16:40 am -
2 stops7h 35m
Deal found 10/13![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:50 pm -
1 stop10h 30m
Wed 12/26:40 am -
2 stops7h 35m
Deal found 10/14![Southwest logo]()
$336
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:31 pm -
1 stop6h 15m
Sat 1/94:42 pm -
1 stop5h 34m
Deal found 10/10![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:25 pm -
1 stop4h 59m
Mon 11/239:58 am -
1 stop4h 37m
Deal found 10/9![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 46m
Sun 12/135:22 pm -
1 stop5h 16m
Deal found 10/11![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:58 pm -
1 stop7h 10m
Sat 1/96:00 am -
2 stops9h 57m
Deal found 10/12![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop5h 09m
Sun 12/136:11 am -
2 stops10h 00m
Deal found 10/10![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 46m
Sat 12/126:07 am -
2 stops10h 04m
Deal found 10/13![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:13 am -
1 stop4h 52m
Wed 12/912:27 pm -
1 stop6h 25m
Deal found 10/13![American Airlines logo]()
$350
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2026.
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/44:25 pm -
1 stop7h 20m
Thu 1/74:40 pm -
1 stop4h 55m
Deal found 10/10![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:31 pm -
1 stop7h 19m
Sun 12/136:44 pm -
1 stop4h 21m
Deal found 10/13![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 27m
Sun 12/138:20 am -
1 stop5h 53m
Deal found 10/12![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:01 pm -
1 stop4h 42m
Sat 10/315:00 am -
2 stops7h 20m
Deal found 10/12![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm -
1 stop7h 20m
Mon 12/146:00 am -
1 stop8h 15m
Deal found 10/13![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:58 pm -
1 stop7h 10m
Sat 1/96:00 am -
2 stops9h 57m
Deal found 10/12![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 46m
Sat 12/126:07 am -
2 stops10h 04m
Deal found 10/14![Delta logo]()
$344
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:56 pm -
1 stop6h 21m
Sun 12/135:15 am -
2 stops7h 25m
Deal found 10/11![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:58 pm -
1 stop7h 46m
Sat 12/126:07 am -
2 stops10h 04m
Deal found 10/12![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:31 pm -
1 stop7h 21m
Sat 12/1210:35 am -
1 stop7h 17m
Deal found 10/13![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:05 am -
2 stops9h 33m
Sun 11/15:00 am -
2 stops7h 31m
Deal found 10/13![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:10 am -
1 stop7h 00m
Thu 12/313:05 pm -
2 stops6h 55m
Deal found 10/10![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:10 pm -
1 stop7h 15m
Sun 11/225:50 am -
1 stop7h 20m
Deal found 10/12![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:30 am -
1 stop6h 12m
Thu 11/122:41 pm -
1 stop5h 55m
Deal found 10/12![United Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:35 am -
1 stop5h 13m
Mon 11/24:00 pm -
1 stop6h 33m
Deal found 10/14![Delta logo]()
$409
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:50 pm -
1 stop10h 30m
Mon 11/306:05 pm -
1 stop5h 30m
Deal found 10/9![Southwest logo]()
$456
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:20 pm -
1 stop7h 34m
Sat 12/55:00 am -
2 stops9h 26m
Deal found 10/11![United Airlines logo]()
$470
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:36 am -
1 stop5h 08m
Mon 11/236:05 am -
2 stops10h 44m
Deal found 10/9![Delta logo]()
$444
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops9h 20m
Sun 11/225:50 am -
1 stop7h 20m
Deal found 10/14![Southwest logo]()
$462
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:56 pm -
1 stop5h 12m
Mon 12/75:00 am -
2 stops11h 13m
Deal found 10/14![United Airlines logo]()
$470
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:35 am -
1 stop6h 45m
Mon 11/25:55 pm -
1 stop4h 38m
Deal found 10/13![Delta logo]()
$448
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop7h 20m
Fri 10/236:58 pm -
1 stop27h 20m
Deal found 10/10![United Airlines logo]()
$708
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated October 14, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated October 14, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:01 pm -
1 stop4h 42m
Sat 10/317:31 am -
1 stop6h 49m
Deal found 10/12![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop7h 38m
Sun 11/15:00 am -
2 stops7h 31m
Deal found 10/13![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:05 pm -
1 stop10h 40m
Sat 11/76:45 am -
1 stop5h 15m
Deal found 10/13![Southwest logo]()
$361
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 35m
Fri 11/205:40 am -
1 stop10h 10m
Deal found 10/12![Southwest logo]()
$371
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops8h 25m
Sun 11/225:50 am -
1 stop7h 20m
Deal found 10/12![Southwest logo]()
$396
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:25 pm -
1 stop4h 59m
Mon 11/239:58 am -
1 stop4h 37m
Deal found 10/9![American Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
2 stops20h 49m
Sun 11/2211:05 am -
1 stop8h 28m
Deal found 10/12![Multiple Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:25 pm -
1 stop6h 13m
Tue 12/16:31 pm -
1 stop4h 52m
Deal found 10/13![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:25 pm -
2 stops7h 10m
Tue 12/16:10 am -
1 stop5h 15m
Deal found 10/13![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:40 am -
2 stops8h 40m
Fri 11/275:50 am -
1 stop7h 20m
Deal found 10/14![Southwest logo]()
$386
This Frontier deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop13h 42m
Thu 12/32:17 pm -
1 stop5h 23m
Deal found 10/13![Frontier logo]()
$266
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:50 pm -
1 stop10h 30m
Wed 12/26:40 am -
2 stops7h 35m
Deal found 10/14![Southwest logo]()
$336
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated October 14, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated October 14, 2026.
This CheapOair deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:28 pm -
1 stop13h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Frontier logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:45 pm -
2 stops25h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$151
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:00 am -
1 stop5h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:04 pm -
1 stop28h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$181
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:50 pm -
1 stop10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Southwest logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 pm -
2 stops35h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:15 pm -
3 stops27h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Multiple Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/221:27 pm -
2 stops9h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![United Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:52 pm -
2 stops47h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Multiple Airlines logo]()
$227
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:01 pm -
1 stop6h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![American Airlines logo]()
$423
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated October 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $266 (Frontier) |
One-way from | $149 (CheapOair) |
Popular in | July |
Cheapest in | August |
Average price | $420 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 14, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sun 11/22
8:28 pm-10:10 am
1 stop13h 42m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$149
Quickest round-trip
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Wed 11/11
8:00 am-1:17 pm
1 stop5h 17m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sat 12/19
4:15 pm-11:55 pm
1 stop7h 40m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 11/12
1:50 pm-12:20 am
1 stop10h 30m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$204
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 11/13
10:25 pm-9:50 am
2 stops35h 25m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sun 11/22
1:27 pm-11:15 pm
2 stops9h 48m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$213
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 11/12
4:15 pm-10:09 pm
2 stops29h 54m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$214
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 10/30
3:04 pm-7:23 pm
2 stops28h 19m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$233
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 10/29
5:52 pm-4:13 pm
2 stops46h 21m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$235
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sat 12/19
12:39 pm-4:44 pm
3 stops28h 05m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$277
Showing 1-10 of 33 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-SHV
DSM-BTR
DSM-LFT
DSM-MLU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-SHV
DSM-BTR
DSM-LFT
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $379). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is below average for this route at the moment.
Des Moines to Louisiana flights typically cost between $380 and $686 in November.The cheapest round-trip price found within the last 5 days was $266 on Frontier (Nov 26-Dec 3).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated October 14, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on October 14, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$482 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$290 | Average$417 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$312 | Average$396 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$384 | FlexibilityNo cancel fee | On-time69% |