$131+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:59 pm -
1 stop5h 40m
Tue 12/13:39 pm -
1 stop6h 59m
Deal found 10/28![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:45 pm -
1 stop7h 55m
Tue 12/86:00 am -
1 stop8h 15m
Deal found 10/25![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:45 pm -
1 stop7h 55m
Tue 12/155:40 am -
2 stops8h 35m
Deal found 10/28![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:52 pm -
1 stop5h 07m
Fri 11/205:30 am -
1 stop5h 14m
Deal found 10/29![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:25 pm -
1 stop7h 35m
Fri 12/113:55 pm -
2 stops7h 10m
Deal found 10/29![Southwest logo]()
$306
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:27 pm -
1 stop7h 40m
Sun 12/137:40 am -
1 stop6h 33m
Deal found 10/29![Delta logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:56 pm -
1 stop5h 12m
Sun 12/135:00 am -
2 stops7h 30m
Deal found 10/29![United Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:31 pm -
1 stop6h 15m
Sat 1/94:42 pm -
1 stop5h 34m
Deal found 10/28![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:23 am -
1 stop4h 05m
Mon 11/236:43 pm -
1 stop4h 40m
Deal found 10/28![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:43 pm -
1 stop4h 16m
Mon 1/46:33 pm -
1 stop4h 35m
Deal found 10/26![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:31 pm -
1 stop7h 25m
Sat 12/1210:35 am -
1 stop7h 17m
Deal found 10/26![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:58 pm -
1 stop7h 10m
Sat 1/96:02 am -
2 stops10h 11m
Deal found 10/30![Delta logo]()
$344
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:59 pm -
1 stop5h 40m
Tue 12/13:39 pm -
1 stop6h 59m
Deal found 10/29![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:45 pm -
1 stop7h 55m
Tue 12/156:10 am -
1 stop5h 15m
Deal found 10/30![Southwest logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:23 am -
1 stop4h 05m
Mon 11/236:43 pm -
1 stop4h 40m
Deal found 10/26![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/68:00 am -
2 stops7h 51m
Sat 4/103:55 pm -
1 stop6h 35m
Deal found 10/27![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/124:56 pm -
1 stop5h 56m
Sat 1/1611:23 am -
1 stop6h 06m
Deal found 10/26![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/53:15 pm -
2 stops7h 41m
Sat 4/103:55 pm -
1 stop6h 35m
Deal found 10/27![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/710:15 am -
2 stops8h 15m
Sat 4/103:20 pm -
1 stop7h 09m
Deal found 10/27![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:50 pm -
1 stop10h 30m
Fri 12/46:00 am -
1 stop8h 15m
Deal found 10/28![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:00 am -
1 stop5h 27m
Sat 1/162:10 pm -
2 stops9h 04m
Deal found 10/26![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
2 stops12h 08m
Thu 12/310:23 am -
2 stops10h 16m
Deal found 10/26![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
2 stops8h 25m
Fri 12/113:55 pm -
2 stops7h 10m
Deal found 10/29![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1312:52 pm -
2 stops8h 51m
Mon 1/186:02 pm -
1 stop4h 28m
Deal found 10/29![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:09 am -
2 stops12h 10m
Sat 1/96:02 am -
2 stops10h 11m
Deal found 10/26![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:31 pm -
1 stop7h 25m
Sat 12/1210:35 am -
1 stop7h 17m
Deal found 10/26![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:01 am -
2 stops11h 43m
Sat 12/126:07 am -
2 stops10h 04m
Deal found 10/26![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/226:55 am -
2 stops7h 05m
Sun 1/246:30 am -
2 stops7h 40m
Deal found 10/29![Southwest logo]()
$398
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 27m
Sun 12/135:27 pm -
1 stop5h 11m
Deal found 10/26![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:45 pm -
1 stop7h 10m
Fri 11/275:50 am -
1 stop7h 20m
Deal found 10/26![Southwest logo]()
$418
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:56 pm -
1 stop6h 57m
Mon 12/75:20 pm -
1 stop5h 01m
Deal found 10/28![United Airlines logo]()
$438
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:30 am -
1 stop6h 40m
Thu 12/316:15 am -
1 stop6h 26m
Deal found 10/29![Delta logo]()
$388
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/263:00 pm -
1 stop6h 46m
Sat 1/304:01 pm -
1 stop6h 29m
Deal found 10/25![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:20 am -
2 stops9h 15m
Sat 1/1610:35 am -
2 stops9h 40m
Deal found 10/27![Southwest logo]()
$441
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:52 pm -
1 stop5h 07m
Sat 11/285:30 am -
1 stop5h 16m
Deal found 10/27![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/81:42 pm -
1 stop7h 54m
Mon 1/115:23 pm -
1 stop5h 07m
Deal found 10/25![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:11 am -
2 stops10h 57m
Sun 11/221:46 pm -
2 stops10h 33m
Deal found 10/26![American Airlines logo]()
$675
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
1 stop6h 50m
Sun 11/221:06 pm -
1 stop5h 01m
Deal found 10/26![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
1 stop6h 31m
Mon 11/2312:41 pm -
2 stops8h 32m
Deal found 10/26![Delta logo]()
$434
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:31 pm -
1 stop7h 13m
Fri 11/1310:22 am -
1 stop4h 17m
Deal found 10/25![American Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:30 am -
2 stops10h 08m
Sat 12/127:00 am -
2 stops9h 13m
Deal found 10/26![United Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1311:22 am -
2 stops10h 21m
Sun 1/172:10 pm -
2 stops31h 13m
Deal found 10/27![United Airlines logo]()
$597
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated October 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:04 pm -
1 stop8h 56m
Fri 11/1310:45 am -
1 stop8h 50m
Deal found 10/25![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:04 pm -
1 stop8h 56m
Thu 11/122:34 pm -
1 stop17h 47m
Deal found 10/25![Multiple Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:30 pm -
2 stops41h 50m
Fri 11/1310:45 am -
1 stop8h 50m
Deal found 10/25![Frontier logo]()
$362
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:52 pm -
1 stop5h 07m
Fri 11/205:30 am -
1 stop5h 14m
Deal found 10/29![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:05 pm -
1 stop10h 40m
Sun 11/226:35 am -
1 stop12h 00m
Deal found 10/26![Southwest logo]()
$392
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:23 am -
1 stop4h 05m
Mon 11/236:43 pm -
1 stop4h 40m
Deal found 10/28![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:10 pm -
1 stop7h 15m
Fri 11/275:50 am -
1 stop7h 20m
Deal found 10/29![Southwest logo]()
$391
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:59 pm -
1 stop5h 40m
Tue 12/13:39 pm -
1 stop6h 59m
Deal found 10/28![Delta logo]()
$281
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 10m
Thu 12/37:41 am -
1 stop7h 03m
Deal found 10/26![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
2 stops12h 08m
Thu 12/33:59 pm -
1 stop6h 39m
Deal found 10/26![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:50 pm -
1 stop10h 30m
Fri 12/46:00 am -
1 stop8h 15m
Deal found 10/28![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop6h 24m
Fri 12/45:20 am -
1 stop5h 33m
Deal found 10/29![Delta logo]()
$380
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop13h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
2 stops20h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:05 pm -
1 stop28h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$153
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 pm -
1 stop5h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$161
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm -
2 stops7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Southwest logo]()
$166
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Southwest logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:25 pm -
1 stop30h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$207
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop5h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$251
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/264:15 pm -
1 stop7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$254
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (Delta) |
One-way from | $131 (CheapOair) |
Popular in | July |
Cheapest in | August |
Average price | $420 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 11/20
9:31 pm-6:20 pm
2 stops20h 49m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$150
Quickest round-trip
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 11/20
6:45 pm-11:52 pm
1 stop5h 07m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$161
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 12/11
4:25 pm-12:15 am
2 stops7h 50m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$166
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 11/26
5:10 am-12:30 pm
2 stops7h 20m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 11/6
10:25 pm-5:10 am
1 stop30h 45m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$207
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sat 12/26
4:15 pm-12:05 am
1 stop7h 50m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Wed 11/25
2:59 pm-8:39 pm
1 stop5h 40m
New Orleans Louis Armstrong
Tue 12/1
3:39 pm-10:38 pm
1 stop6h 59m
$281
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 11/26
8:00 am-1:16 pm
1 stop5h 16m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$292
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sat 12/12
12:45 pm-8:40 pm
1 stop7h 55m
New Orleans Louis Armstrong
Tue 12/15
6:10 am-11:25 am
1 stop5h 15m
$330
Des MoinesShreveport
DSM Des Moines - SHV Shreveport
DSMSHV
Des Moines
Thu 11/19
5:23 am-9:28 am
1 stop4h 05m
Shreveport
Mon 11/23
6:43 pm-11:23 pm
1 stop4h 40m
$339
Showing 1-10 of 38 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-SHV
DSM-BTR
DSM-LCH
DSM-LFT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-SHV
DSM-BTR
DSM-LCH
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $379). Flying from Des Moines to Louisiana in July is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is below average for this route at the moment.
Des Moines to Louisiana flights typically cost between $324 and $496 in November.The cheapest round-trip price found within the last 5 days was $281 on Delta (Nov 25-Dec 1).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 28 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated October 30, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on October 30, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$411 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$287 | Average$482 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$402 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$384 | FlexibilityNo cancel fee | On-time69% |