$98+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Aug 22 — Aug 291
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:19 pm
DSM
- MSY
1 stop6h 32m
Frontier
Sun 8/309:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 7/18![Frontier logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/201:58 pm
DSM
- MSY
1 stop21h 57m
Multiple Airlines
Sat 9/265:02 pm
MSY
- DSM
2 stops26h 55m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$288
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Sun 8/169:48 pm
MSY
- DSM
1 stop15h 46m
Frontier
Deal found 7/20![Frontier logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:41 pm
DSM
- MSY
2 stops24h 43m
Multiple Airlines
Wed 8/198:59 pm
MSY
- DSM
1 stop24h 01m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:22 pm
DSM
- BTR
1 stop4h 33m
American Airlines
Mon 8/246:14 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 7/18![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm
DSM
- BTR
2 stops7h 16m
Delta
Mon 8/243:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/18![Delta logo]()
$314
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:33 am
DSM
- MSY
1 stop4h 55m
American Airlines
Sat 9/57:41 am
MSY
- DSM
1 stop5h 44m
American Airlines
Deal found 7/19![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am
DSM
- MSY
2 stops6h 45m
Southwest
Thu 8/273:50 pm
MSY
- DSM
1 stop6h 20m
Southwest
Deal found 7/23![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:13 pm
DSM
- AEX
1 stop4h 01m
American Airlines
Sat 8/85:14 pm
AEX
- DSM
1 stop6h 02m
American Airlines
Deal found 7/20![American Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:10 pm
DSM
- MSY
1 stop5h 00m
Southwest
Tue 11/37:20 am
MSY
- DSM
1 stop10h 25m
Southwest
Deal found 7/19![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:50 am
DSM
- AEX
2 stops9h 35m
United Airlines
Sat 8/89:43 am
AEX
- DSM
2 stops11h 39m
United Airlines
Deal found 7/20![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:41 pm
DSM
- MSY
2 stops24h 43m
Multiple Airlines
Thu 8/209:36 pm
MSY
- DSM
1 stop15h 58m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$339
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:40 am
DSM
- BTR
1 stop7h 07m
Delta
Mon 8/243:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/18![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:10 pm
DSM
- MSY
1 stop5h 00m
Southwest
Mon 10/56:45 am
MSY
- DSM
1 stop4h 25m
Southwest
Deal found 7/20![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:50 am
DSM
- AEX
2 stops9h 35m
United Airlines
Sat 8/89:43 am
AEX
- DSM
2 stops11h 39m
United Airlines
Deal found 7/20![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:22 pm
DSM
- BTR
1 stop4h 33m
American Airlines
Tue 8/116:14 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 7/23![American Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm
DSM
- BTR
2 stops7h 16m
Delta
Mon 8/243:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/18![Delta logo]()
$314
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am
DSM
- MSY
2 stops6h 45m
Southwest
Thu 8/273:50 pm
MSY
- DSM
1 stop6h 20m
Southwest
Deal found 7/23![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 pm
DSM
- MSY
1 stop5h 00m
Southwest
Mon 10/125:50 am
MSY
- DSM
1 stop7h 30m
Southwest
Deal found 7/21![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 am
DSM
- BTR
1 stop7h 01m
United Airlines
Sat 8/297:15 am
BTR
- DSM
1 stop6h 59m
United Airlines
Deal found 7/18![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:54 pm
DSM
- AEX
1 stop6h 47m
Delta
Sat 8/811:44 am
AEX
- DSM
2 stops8h 55m
Delta
Deal found 7/20![Delta logo]()
$394
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:21 pm
DSM
- BTR
2 stops8h 07m
United Airlines
Mon 8/2412:00 pm
BTR
- DSM
2 stops9h 23m
United Airlines
Deal found 7/18![United Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:10 pm
DSM
- MSY
1 stop5h 00m
Southwest
Sun 10/185:00 am
MSY
- DSM
1 stop6h 20m
Southwest
Deal found 7/22![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:21 am
DSM
- BTR
2 stops11h 10m
United Airlines
Sat 10/315:00 am
BTR
- DSM
2 stops9h 19m
United Airlines
Deal found 7/22![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Tue 9/291:30 pm
MSY
- DSM
2 stops7h 30m
Southwest
Deal found 7/22![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:10 pm
DSM
- MSY
1 stop5h 00m
Southwest
Mon 11/26:00 pm
MSY
- DSM
1 stop5h 00m
Southwest
Deal found 7/19![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:45 pm
DSM
- MSY
2 stops9h 30m
United Airlines
Sat 12/53:30 pm
MSY
- DSM
1 stop7h 00m
United Airlines
Deal found 7/20![United Airlines logo]()
$440
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:20 am
DSM
- MSY
2 stops9h 25m
Southwest
Mon 11/166:40 am
MSY
- DSM
2 stops7h 30m
Southwest
Deal found 7/19![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:35 pm
DSM
- MSY
1 stop8h 05m
United Airlines
Mon 11/27:00 am
MSY
- DSM
1 stop5h 30m
United Airlines
Deal found 7/20![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:35 pm
DSM
- MSY
1 stop8h 05m
United Airlines
Tue 11/106:08 pm
MSY
- DSM
1 stop5h 32m
United Airlines
Deal found 7/18![United Airlines logo]()
$461
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated July 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:48 pm
DSM
- BTR
1 stop6h 09m
American Airlines
Tue 8/46:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 7/19![American Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:13 pm
DSM
- AEX
1 stop4h 01m
American Airlines
Sat 8/85:14 pm
AEX
- DSM
1 stop6h 02m
American Airlines
Deal found 7/20![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:50 am
DSM
- AEX
2 stops9h 35m
United Airlines
Sat 8/89:43 am
AEX
- DSM
2 stops11h 39m
United Airlines
Deal found 7/20![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- MSY
1 stop31h 43m
Multiple Airlines
Wed 8/125:09 pm
MSY
- DSM
2 stops30h 10m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$348
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Sun 8/169:48 pm
MSY
- DSM
1 stop15h 46m
Frontier
Deal found 7/20![Frontier logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:41 pm
DSM
- MSY
2 stops24h 43m
Multiple Airlines
Wed 8/198:59 pm
MSY
- DSM
1 stop24h 01m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:41 pm
DSM
- MSY
2 stops24h 43m
Multiple Airlines
Thu 8/209:36 pm
MSY
- DSM
1 stop15h 58m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:22 pm
DSM
- BTR
1 stop4h 33m
American Airlines
Mon 8/246:14 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 7/18![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm
DSM
- BTR
2 stops7h 16m
Delta
Mon 8/243:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/18![Delta logo]()
$314
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am
DSM
- MSY
2 stops6h 45m
Southwest
Thu 8/273:50 pm
MSY
- DSM
1 stop6h 20m
Southwest
Deal found 7/23![Southwest logo]()
$322
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:19 pm
DSM
- MSY
1 stop6h 32m
Frontier
Sun 8/309:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 7/18![Frontier logo]()
$278
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
DSM
- MSY
1 stop6h 58m
United Airlines
Tue 9/14:25 pm
MSY
- DSM
1 stop7h 19m
United Airlines
Deal found 7/19![United Airlines logo]()
$317
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:12 pm
DSM
- MSY
2 stops48h 50m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$98
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:25 pm
DSM
- MSY
1 stop7h 20m
Southwest
Deal found 7/21![Southwest logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:51 pm
DSM
- MSY
2 stops25h 18m
Frontier
Deal found 7/21![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm
DSM
- MSY
3 stops18h 38m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$215
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:45 pm
DSM
- MSY
1 stop7h 00m
Southwest
Deal found 7/18![Southwest logo]()
$224
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:15 pm
DSM
- MSY
1 stop7h 40m
Southwest
Deal found 7/18![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:20 am
DSM
- MSY
1 stop11h 15m
Southwest
Deal found 7/21![Southwest logo]()
$249
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:13 pm
DSM
- BTR
1 stop6h 42m
American Airlines
Deal found 7/21![American Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:41 pm
DSM
- BTR
1 stop7h 49m
American Airlines
Deal found 7/20![American Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:24 pm
DSM
- BTR
2 stops7h 22m
United Airlines
Deal found 7/20![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:41 pm
DSM
- BTR
1 stop7h 49m
American Airlines
Deal found 7/21![American Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:40 pm
DSM
- BTR
2 stops9h 06m
United Airlines
Deal found 7/21![United Airlines logo]()
$421
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $278 (CheapOair) |
One-way from | $98 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $486 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Sat 8/22
5:40 am-12:47 pm
1 stop7h 07m
Baton Rouge Ryan
Mon 8/24
3:57 pm-10:37 pm
1 stop6h 40m
$309
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Fri 8/21
2:45 pm-10:01 pm
2 stops7h 16m
Baton Rouge Ryan
Mon 8/24
3:57 pm-10:37 pm
1 stop6h 40m
$314
Quickest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/1
7:10 pm-12:10 am
1 stop5h 00m
New Orleans Louis Armstrong
Mon 10/5
6:45 am-11:10 am
1 stop4h 25m
$317
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 8/25
6:10 am-12:55 pm
2 stops6h 45m
New Orleans Louis Armstrong
Thu 8/27
3:50 pm-10:10 pm
1 stop6h 20m
$322
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Tue 8/4
5:50 am-3:25 pm
2 stops9h 35m
Alexandria
Sat 8/8
9:43 am-9:22 pm
2 stops11h 39m
$339
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/8
7:10 pm-12:10 am
1 stop5h 00m
New Orleans Louis Armstrong
Mon 10/12
5:50 am-1:20 pm
1 stop7h 30m
$341
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/15
7:10 pm-12:10 am
1 stop5h 00m
New Orleans Louis Armstrong
Sun 10/18
5:00 am-11:20 am
1 stop6h 20m
$367
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Fri 9/25
3:50 pm-10:40 pm
2 stops6h 50m
New Orleans Louis Armstrong
Tue 9/29
1:30 pm-9:00 pm
2 stops7h 30m
$377
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/29
7:10 pm-12:10 am
1 stop5h 00m
New Orleans Louis Armstrong
Mon 11/2
6:00 pm-11:00 pm
1 stop5h 00m
$387
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Tue 8/25
6:15 am-1:16 pm
1 stop7h 01m
Baton Rouge Ryan
Sat 8/29
7:15 am-2:14 pm
1 stop6h 59m
$389
Showing 1-10 of 30 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $356). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is below average for this route at the moment.
Des Moines to Louisiana flights typically cost between $392 and $614 in August.The cheapest round-trip price found within the last 5 days was $278 on Frontier (Aug 28-Aug 30).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 68 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated July 23, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on July 23, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$432 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$425 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$277 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |