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$186+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Jan 6 — Jan 131
Tue 1/6
Tue 1/13
1 adult, Economy
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Cheap flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:44 pmDSM - MSY
1 stop21h 07mAllegiant Air
Mon 12/151:41 pmMSY - DSM
1 stop27h 21mAllegiant Air
Deal found 12/4$248
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:32 pmDSM - MSY
2 stops39h 37mMultiple Airlines
Sun 12/145:59 pmMSY - DSM
1 stop27h 10mMultiple Airlines
Deal found 12/4$309
This United Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:00 pmDSM - BTR
1 stop6h 18mUnited Airlines
Wed 12/247:10 amBTR - DSM
2 stops9h 15mUnited Airlines
Deal found 12/5$338
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:21 pmDSM - MSY
2 stops52h 36mMultiple Airlines
Mon 12/151:41 pmMSY - DSM
1 stop27h 21mMultiple Airlines
Deal found 12/4$342
This American Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:39 pmDSM - AEX
1 stop4h 59mAmerican Airlines
Wed 12/245:44 amAEX - DSM
1 stop5h 03mAmerican Airlines
Deal found 12/5$346
This American Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:39 pmDSM - BTR
1 stop5h 32mAmerican Airlines
Wed 12/245:32 amBTR - DSM
1 stop5h 15mAmerican Airlines
Deal found 12/5$359
This American Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:39 pmDSM - MSY
1 stop6h 47mAmerican Airlines
Thu 1/17:30 amMSY - DSM
1 stop7h 23mAmerican Airlines
Deal found 12/5$375
This American Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:16 pmDSM - MSY
1 stop6h 49mAmerican Airlines
Mon 1/56:53 pmMSY - DSM
1 stop5h 44mAmerican Airlines
Deal found 12/5$429
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:45 amDSM - BTR
2 stops10h 19mAmerican Airlines
Fri 12/265:32 amBTR - DSM
1 stop5h 17mAmerican Airlines
Deal found 12/7$445
This Mytrip deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:16 pmDSM - MSY
1 stop13h 01mMultiple Airlines
Tue 12/303:10 pmMSY - DSM
1 stop8h 00mMultiple Airlines
Deal found 12/7$515
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:00 amDSM - BTR
2 stops11h 23mUnited Airlines
Fri 12/2612:11 pmBTR - DSM
2 stops9h 29mUnited Airlines
Deal found 12/7$574
This Delta deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:16 pmDSM - BTR
1 stop7h 37mDelta
Tue 12/96:07 amBTR - DSM
1 stop7h 24mDelta
Deal found 12/6$929

Find flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated December 7, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$233
(Delta)

One-way from

$186
(Mytrip)

Popular in

February

Cheapest in

November

Average price

$415
Provider with most accurate pricing for Des Moines-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-New Orleans Louis Armstrong flights.
Search Deals
From Des Moines to Louisiana
Search Deals
One-way flight from Des Moines to Louisiana
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 7, 2025.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Des Moines

Fly to

Louisiana

Route

Depart

Return

Price

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 1/17

1:03 pm-6:00 pm

1 stop4h 57m

New Orleans Louis Armstrong

Sat 1/24

7:26 am-12:15 pm

1 stop4h 49m

$233

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Wed 1/21

11:35 am-6:04 pm

1 stop6h 29m

Baton Rouge Ryan

Wed 1/28

7:07 am-3:45 pm

1 stop8h 38m

$250

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Wed 1/21

5:16 pm-10:01 pm

1 stop4h 45m

Baton Rouge Ryan

Wed 1/28

1:37 pm-8:54 pm

2 stops7h 17m

$254

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 1/24

1:03 pm-8:12 pm

1 stop7h 09m

New Orleans Louis Armstrong

Mon 2/2

5:29 pm-10:29 pm

1 stop5h 00m

$286

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Thu 1/15

2:20 pm-11:20 pm

1 stop9h 00m

New Orleans Louis Armstrong

Tue 1/20

5:10 pm-9:10 pm

1 stop4h 00m

$287

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 2/18

3:20 pm-7:45 pm

1 stop4h 25m

New Orleans Louis Armstrong

Mon 2/23

6:50 am-10:50 am

1 stop4h 00m

$287

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Tue 1/20

5:16 pm-11:25 pm

1 stop6h 09m

New Orleans Louis Armstrong

Tue 1/27

5:23 am-10:41 am

1 stop5h 18m

$287

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 1/24

3:04 pm-9:51 pm

1 stop6h 47m

New Orleans Louis Armstrong

Mon 2/2

12:40 pm-9:50 pm

2 stops9h 10m

$291

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 2/7

1:35 pm-9:32 pm

1 stop7h 57m

New Orleans Louis Armstrong

Wed 2/11

5:35 pm-10:30 pm

1 stop4h 55m

$295

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Fri 3/6

7:58 pm-9:46 am

2 stops13h 48m

New Orleans Louis Armstrong

Tue 3/10

8:29 pm-4:02 pm

1 stop19h 33m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 20 results
1
2

Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in May is currently the most expensive (average of $332). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LA?

Find hourly flight availability from Des Moines to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 7, 2025.

When flying from Des Moines to Louisiana, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 41% versus a flight in the morning.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated December 7, 2025.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,252 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,252 reviews
Southwest
8.0
Very good
4,252 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,013 reviews
Southwest
8.0
Very good
4,252 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,076 reviews
Southwest
8.0
Very good
4,252 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,042 reviews
Southwest
8.0
Very good
4,252 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 4h 57m. The distance between Des Moines and Louisiana is about 820 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Des Moines to Louisiana?

    Most travelers choose Des Moines - New Orleans Louis Armstrong, Des Moines - Baton Rouge Ryan or Des Moines - Alexandria when deciding on the best route from Des Moines to Louisiana.

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in May is currently the most expensive (average of $332). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$414FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$405FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$277Average$402FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$331Average$432FlexibilityNo cancel feeOn-time69%

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