$109+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:26 pm
DSM
- MSY
1 stop6h 37m
Frontier
Thu 6/259:48 pm
MSY
- DSM
1 stop15h 43m
Frontier
Deal found 5/12![Frontier logo]()
$260
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:20 am
DSM
- MSY
1 stop5h 55m
Southwest
Tue 6/303:55 pm
MSY
- DSM
1 stop6h 50m
Southwest
Deal found 5/11![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- MSY
1 stop4h 30m
Southwest
Thu 6/45:40 am
MSY
- DSM
1 stop5h 50m
Southwest
Deal found 5/8![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:41 am
DSM
- BTR
1 stop7h 06m
Delta
Wed 8/53:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 5/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:45 am
DSM
- MSY
1 stop6h 14m
Delta
Sat 9/56:30 am
MSY
- DSM
1 stop6h 52m
Delta
Deal found 5/9![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:45 am
DSM
- MSY
1 stop6h 14m
Delta
Mon 9/145:30 am
MSY
- DSM
1 stop4h 44m
Delta
Deal found 5/8![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
DSM
- MSY
2 stops7h 20m
Southwest
Sat 9/57:15 am
MSY
- DSM
1 stop4h 15m
Southwest
Deal found 5/10![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:48 pm
DSM
- BTR
1 stop5h 21m
American Airlines
Wed 5/276:16 pm
BTR
- DSM
1 stop5h 41m
American Airlines
Deal found 5/8![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:25 pm
DSM
- MSY
2 stops7h 35m
Southwest
Tue 9/1512:45 pm
MSY
- DSM
2 stops8h 15m
Southwest
Deal found 5/11![Southwest logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:48 pm
DSM
- MSY
1 stop6h 40m
American Airlines
Mon 6/156:17 pm
MSY
- DSM
1 stop5h 55m
American Airlines
Deal found 5/11![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:20 am
DSM
- BTR
1 stop5h 00m
United Airlines
Tue 7/144:09 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 5/8![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:18 pm
DSM
- MSY
1 stop5h 29m
American Airlines
Sat 8/159:07 am
MSY
- DSM
2 stops10h 07m
American Airlines
Deal found 5/11![American Airlines logo]()
$353
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:39 pm
DSM
- MSY
1 stop5h 10m
Delta
Wed 7/14:30 pm
MSY
- DSM
1 stop4h 38m
Delta
Deal found 5/9![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- MSY
1 stop4h 30m
Southwest
Thu 6/45:40 am
MSY
- DSM
1 stop5h 50m
Southwest
Deal found 5/8![Southwest logo]()
$316
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:48 pm
DSM
- BTR
2 stops9h 11m
American Airlines
Sat 5/306:22 pm
BTR
- DSM
1 stop5h 55m
American Airlines
Deal found 5/11![American Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:24 pm
DSM
- BTR
2 stops7h 22m
United Airlines
Tue 7/144:09 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 5/8![United Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:40 pm
DSM
- MSY
1 stop7h 15m
Southwest
Tue 6/163:55 pm
MSY
- DSM
1 stop6h 50m
Southwest
Deal found 5/7![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:48 pm
DSM
- MSY
1 stop4h 43m
American Airlines
Fri 6/1211:20 am
MSY
- DSM
1 stop7h 02m
American Airlines
Deal found 5/7![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:15 pm
DSM
- MSY
1 stop6h 24m
Delta
Thu 9/105:30 am
MSY
- DSM
1 stop4h 44m
Delta
Deal found 5/10![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:02 pm
DSM
- AEX
1 stop4h 58m
United Airlines
Sat 8/299:45 am
AEX
- DSM
1 stop4h 29m
United Airlines
Deal found 5/8![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:02 pm
DSM
- AEX
1 stop4h 30m
American Airlines
Sat 6/1310:44 am
AEX
- DSM
1 stop5h 19m
American Airlines
Deal found 5/8![American Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:50 pm
DSM
- MSY
1 stop6h 30m
Southwest
Sun 10/186:10 am
MSY
- DSM
1 stop9h 50m
Southwest
Deal found 5/12![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:54 am
DSM
- MSY
1 stop4h 31m
Delta
Mon 8/34:28 pm
MSY
- DSM
1 stop4h 31m
Delta
Deal found 5/11![Delta logo]()
$383
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:15 am
DSM
- BTR
1 stop4h 58m
United Airlines
Tue 8/254:10 pm
BTR
- DSM
1 stop6h 20m
United Airlines
Deal found 5/10![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:05 am
DSM
- MSY
1 stop7h 45m
Southwest
Thu 5/281:50 pm
MSY
- DSM
1 stop8h 05m
Southwest
Deal found 5/9![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:25 am
DSM
- MSY
2 stops9h 35m
Southwest
Wed 7/19:35 am
MSY
- DSM
1 stop8h 45m
Southwest
Deal found 5/9![Southwest logo]()
$391
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:25 pm
DSM
- AEX
1 stop7h 00m
Delta
Wed 7/111:46 am
AEX
- DSM
2 stops8h 55m
Delta
Deal found 5/10![Delta logo]()
$444
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/194:40 pm
DSM
- MSY
2 stops7h 40m
Southwest
Tue 6/236:10 am
MSY
- DSM
2 stops8h 55m
Southwest
Deal found 5/7![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:50 am
DSM
- AEX
2 stops9h 00m
United Airlines
Sat 6/139:43 am
AEX
- DSM
2 stops9h 42m
United Airlines
Deal found 5/8![United Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Wed 8/510:26 am
BTR
- DSM
2 stops10h 32m
Delta
Deal found 5/12![Delta logo]()
$504
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated May 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
DSM
- AEX
1 stop4h 37m
American Airlines
Sun 5/245:40 pm
AEX
- DSM
1 stop6h 17m
American Airlines
Deal found 5/11![American Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:48 pm
DSM
- BTR
1 stop5h 21m
American Airlines
Wed 5/276:16 pm
BTR
- DSM
1 stop5h 41m
American Airlines
Deal found 5/8![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- MSY
1 stop4h 30m
Southwest
Thu 6/45:40 am
MSY
- DSM
1 stop5h 50m
Southwest
Deal found 5/8![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:30 am
DSM
- MSY
1 stop4h 30m
Southwest
Fri 6/55:10 am
MSY
- DSM
1 stop7h 40m
Southwest
Deal found 5/8![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:02 pm
DSM
- MSY
1 stop4h 26m
American Airlines
Mon 6/86:01 pm
MSY
- DSM
1 stop5h 57m
American Airlines
Deal found 5/11![American Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:02 pm
DSM
- AEX
1 stop4h 30m
American Airlines
Sat 6/1310:44 am
AEX
- DSM
1 stop5h 19m
American Airlines
Deal found 5/8![American Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:48 pm
DSM
- MSY
1 stop6h 40m
American Airlines
Mon 6/156:17 pm
MSY
- DSM
1 stop5h 55m
American Airlines
Deal found 5/11![American Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:48 pm
DSM
- MSY
1 stop4h 43m
American Airlines
Fri 6/1211:20 am
MSY
- DSM
1 stop7h 02m
American Airlines
Deal found 5/7![American Airlines logo]()
$359
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:26 pm
DSM
- MSY
1 stop6h 37m
Frontier
Thu 6/259:48 pm
MSY
- DSM
1 stop15h 43m
Frontier
Deal found 5/12![Frontier logo]()
$260
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:20 am
DSM
- MSY
1 stop5h 55m
Southwest
Tue 6/303:55 pm
MSY
- DSM
1 stop6h 50m
Southwest
Deal found 5/11![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:02 pm
DSM
- MSY
1 stop4h 26m
American Airlines
Mon 6/296:17 pm
MSY
- DSM
1 stop5h 55m
American Airlines
Deal found 5/12![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:28 am
DSM
- AEX
1 stop4h 57m
Delta
Wed 7/15:09 pm
AEX
- DSM
1 stop5h 22m
Delta
Deal found 5/10![Delta logo]()
$438
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Frontier deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Deal found 5/8![Frontier logo]()
$109
This Frontier deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Deal found 5/8![Frontier logo]()
$115
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:31 pm
DSM
- MSY
1 stop24h 09m
Frontier
Deal found 5/12![Frontier logo]()
$126
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:20 am
DSM
- MSY
1 stop4h 41m
United Airlines
Deal found 5/11![United Airlines logo]()
$156
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 am
DSM
- MSY
2 stops7h 59m
American Airlines
Deal found 5/12![American Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:02 pm
DSM
- MSY
2 stops47h 19m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$166
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:50 pm
DSM
- MSY
1 stop6h 30m
Southwest
Deal found 5/12![Southwest logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:57 pm
DSM
- MSY
2 stops24h 24m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
DSM
- MSY
2 stops34h 26m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:37 pm
DSM
- MSY
2 stops47h 12m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$190
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Southwest) |
One-way from | $109 (Frontier) |
Popular in | May |
Cheapest in | September |
Average price | $464 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 6/24
6:39 pm-11:49 pm
1 stop5h 10m
New Orleans Louis Armstrong
Wed 7/1
4:30 pm-9:08 pm
1 stop4h 38m
$311
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 6/2
5:30 am-10:00 am
1 stop4h 30m
New Orleans Louis Armstrong
Thu 6/4
5:40 am-11:30 am
1 stop5h 50m
$316
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Tue 5/26
1:48 pm-10:59 pm
2 stops9h 11m
Baton Rouge Ryan
Sat 5/30
6:22 pm-12:17 am
1 stop5h 55m
$344
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 6/11
4:40 pm-11:55 pm
1 stop7h 15m
New Orleans Louis Armstrong
Tue 6/16
3:55 pm-10:45 pm
1 stop6h 50m
$359
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 6/10
4:48 pm-9:31 pm
1 stop4h 43m
New Orleans Louis Armstrong
Fri 6/12
11:20 am-6:22 pm
1 stop7h 02m
$359
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Sun 6/7
7:02 pm-11:32 pm
1 stop4h 30m
Alexandria
Sat 6/13
10:44 am-4:03 pm
1 stop5h 19m
$368
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Mon 9/7
2:15 pm-8:39 pm
1 stop6h 24m
New Orleans Louis Armstrong
Thu 9/10
5:30 am-10:14 am
1 stop4h 44m
$377
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/15
1:50 pm-8:20 pm
1 stop6h 30m
New Orleans Louis Armstrong
Sun 10/18
6:10 am-4:00 pm
1 stop9h 50m
$377
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sun 5/24
7:05 am-2:50 pm
1 stop7h 45m
New Orleans Louis Armstrong
Thu 5/28
1:50 pm-9:55 pm
1 stop8h 05m
$381
Quickest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 7/30
10:54 am-3:25 pm
1 stop4h 31m
New Orleans Louis Armstrong
Mon 8/3
4:28 pm-8:59 pm
1 stop4h 31m
$383
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $151). Flying from Des Moines to Louisiana in May is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated May 12, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on May 12, 2026.
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Des Moines to Louisiana flights
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Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$414 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$432 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$394 | FlexibilityNo cancel fee | On-time69% |