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$121+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
ago. 23 — ago. 301
sáb. 8/23
sáb. 8/30
1 adult, Economy
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Cheap flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated agosto 18, 2025.

Round-trip from

$221
(Kiwi.com)

One-way from

$121
(Kiwi.com)

Popular in

February

Cheapest in

November

Average price

$401
From Des Moines to Louisiana
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One-way flight from Des Moines to Louisiana
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Highest demand for flights based on searches. 9% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/210:41 amDSM - MSY
1 stop13h 11mMultiple Airlines
jue. 10/96:30 pmMSY - DSM
1 stop22h 44mMultiple Airlines
Deal found 8/18$221
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/169:03 pmDSM - MSY
1 stop21h 20mMultiple Airlines
mié. 11/194:31 pmMSY - DSM
1 stop15h 58mMultiple Airlines
Deal found 8/18$236
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/115:49 pmDSM - MSY
1 stop16h 02mMultiple Airlines
lun. 9/158:19 pmMSY - DSM
2 stops37h 05mMultiple Airlines
Deal found 8/18$245
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/45:49 pmDSM - MSY
1 stop16h 02mMultiple Airlines
dom. 9/710:56 amMSY - DSM
1 stop26h 36mMultiple Airlines
Deal found 8/17$247
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:12 pmDSM - BTR
1 stop5h 00mDelta
mié. 10/110:27 amBTR - DSM
1 stop7h 18mDelta
Deal found 8/17$249
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/189:19 amDSM - MSY
1 stop13h 18mMultiple Airlines
mié. 10/228:22 pmMSY - DSM
1 stop13h 29mMultiple Airlines
Deal found 8/18$265
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/189:19 amDSM - MSY
1 stop13h 18mMultiple Airlines
mar. 10/2112:20 pmMSY - DSM
1 stop19h 39mMultiple Airlines
Deal found 8/18$267
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/122:12 pmDSM - MSY
2 stops28h 41mMultiple Airlines
dom. 9/1410:56 amMSY - DSM
1 stop6h 03mMultiple Airlines
Deal found 8/15$275
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:10 amDSM - MSY
1 stop6h 43mAmerican Airlines
mar. 10/76:10 pmMSY - DSM
1 stop5h 06mAmerican Airlines
Deal found 8/16$276
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/302:05 pmDSM - MSY
1 stop6h 12mDelta
mar. 10/710:32 amMSY - DSM
1 stop7h 12mDelta
Deal found 8/16$277
This Mytrip deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/610:50 amDSM - MSY
1 stop11h 15mMultiple Airlines
dom. 11/96:15 amMSY - DSM
1 stop13h 58mMultiple Airlines
Deal found 8/18$278
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/1911:23 amDSM - BTR
1 stop4h 30mDelta
sáb. 8/236:00 amBTR - DSM
1 stop4h 38mDelta
Deal found 8/15$324

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Des Moines

Fly to

Louisiana

Route

Depart

Return

Price

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

jue. 10/2

10:41 am-11:52 pm

1 stop13h 11m

New Orleans Louis Armstrong

jue. 10/9

6:30 pm-5:14 pm

1 stop22h 44m

$221

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

dom. 11/16

9:03 pm-6:23 pm

1 stop21h 20m

New Orleans Louis Armstrong

mié. 11/19

4:31 pm-8:29 am

1 stop15h 58m

$236

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

jue. 9/11

5:49 pm-9:51 am

1 stop16h 02m

New Orleans Louis Armstrong

lun. 9/15

8:19 pm-9:24 am

2 stops37h 05m

$245

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

jue. 9/4

5:49 pm-9:51 am

1 stop16h 02m

New Orleans Louis Armstrong

dom. 9/7

10:56 am-1:32 pm

1 stop26h 36m

$247

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

sáb. 9/27

11:25 am-3:52 pm

1 stop4h 27m

Baton Rouge Ryan

mié. 10/1

6:20 am-1:20 pm

1 stop7h 00m

$249

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

sáb. 10/18

9:19 am-10:37 pm

1 stop13h 18m

New Orleans Louis Armstrong

mié. 10/22

8:22 pm-9:51 am

1 stop13h 29m

$265

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

sáb. 10/18

9:19 am-10:37 pm

1 stop13h 18m

New Orleans Louis Armstrong

mar. 10/21

12:20 pm-7:59 am

1 stop19h 39m

$267

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

vie. 9/12

2:12 pm-6:53 pm

2 stops28h 41m

New Orleans Louis Armstrong

dom. 9/14

10:56 am-4:59 pm

1 stop6h 03m

$275

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

mar. 9/30

5:10 am-11:53 am

1 stop6h 43m

New Orleans Louis Armstrong

mar. 10/7

6:10 pm-11:16 pm

1 stop5h 06m

$276

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

sáb. 9/27

7:08 am-5:07 pm

2 stops9h 59m

Baton Rouge Ryan

mié. 10/1

8:13 am-6:30 pm

2 stops10h 17m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 20 results
1
2

Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $256). Flying from Des Moines to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LA?

Find hourly flight availability from Des Moines to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Louisiana as you normally would.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated agosto 18, 2025.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,925 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 4h 27m. The distance between Des Moines and Louisiana is about 773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Des Moines to Louisiana?

    Most travelers choose Des Moines - New Orleans Louis Armstrong, Des Moines - Baton Rouge Ryan or Des Moines - Alexandria when deciding on the best route from Des Moines to Louisiana.

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $256). Flying from Des Moines to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$399FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$409FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$403FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$331Average$423FlexibilityNo cancel feeOn-time69%

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