$150+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Dec 13 — Dec 201
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2026.
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:15 pm -
1 stop5h 30m
Wed 1/64:00 pm -
1 stop5h 35m
Deal found 11/9![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:31 pm -
1 stop7h 30m
Sat 1/910:32 am -
1 stop6h 57m
Deal found 11/12![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 27m
Sun 12/135:27 pm -
1 stop5h 11m
Deal found 11/10![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:38 am -
1 stop5h 02m
Tue 12/156:07 am -
1 stop8h 06m
Deal found 11/9![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:30 am -
2 stops7h 49m
Sat 1/96:02 am -
1 stop6h 40m
Deal found 11/10![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:09 am -
2 stops8h 43m
Wed 12/1611:50 am -
1 stop6h 18m
Deal found 11/9![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:38 pm -
1 stop4h 21m
Wed 12/236:33 pm -
1 stop4h 40m
Deal found 11/10![American Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:17 pm -
2 stops38h 21m
Fri 12/46:05 pm -
1 stop18h 04m
Deal found 11/9![Multiple Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:43 pm -
1 stop4h 16m
Sat 12/196:33 pm -
1 stop4h 40m
Deal found 11/9![American Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
1 stop7h 15m
Sat 12/123:56 pm -
1 stop6h 25m
Deal found 11/10![United Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:56 pm -
1 stop6h 57m
Sat 12/196:05 pm -
1 stop5h 54m
Deal found 11/10![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:45 pm -
1 stop7h 55m
Mon 12/146:00 am -
1 stop8h 15m
Deal found 11/11![Southwest logo]()
$382
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 13, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 13, 2026.
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/55:15 pm -
1 stop4h 46m
Sat 4/1010:29 am -
1 stop5h 58m
Deal found 11/10![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:00 am -
1 stop7h 15m
Fri 1/87:15 am -
1 stop7h 04m
Deal found 11/10![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:31 pm -
1 stop6h 15m
Sat 1/94:42 pm -
1 stop5h 34m
Deal found 11/9![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:25 am -
1 stop4h 50m
Sat 1/96:00 am -
1 stop8h 40m
Deal found 11/10![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:23 pm -
1 stop4h 43m
Sun 1/106:02 am -
1 stop4h 59m
Deal found 11/11![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:22 am -
2 stops10h 24m
Sun 1/104:01 pm -
1 stop6h 29m
Deal found 11/11![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 27m
Sun 12/135:27 pm -
1 stop5h 11m
Deal found 11/11![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
2 stops8h 25m
Fri 12/113:55 pm -
2 stops7h 10m
Deal found 11/9![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:56 pm -
1 stop6h 57m
Sat 12/196:05 pm -
1 stop5h 54m
Deal found 11/10![United Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:38 am -
1 stop5h 02m
Tue 12/156:07 am -
1 stop8h 06m
Deal found 11/9![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:15 pm -
1 stop5h 30m
Thu 12/241:00 pm -
2 stops9h 05m
Deal found 11/8![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:20 pm -
1 stop7h 34m
Fri 12/1110:05 am -
1 stop6h 08m
Deal found 11/9![United Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:30 am -
2 stops7h 49m
Sat 1/96:02 am -
1 stop6h 40m
Deal found 11/9![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:55 am -
2 stops9h 20m
Sun 1/177:05 am -
1 stop10h 40m
Deal found 11/12![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:30 am -
2 stops12h 14m
Tue 12/1511:50 am -
2 stops8h 49m
Deal found 11/9![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:20 pm -
1 stop7h 34m
Sun 12/137:00 am -
1 stop5h 30m
Deal found 11/10![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am -
2 stops8h 25m
Fri 12/256:10 am -
1 stop5h 15m
Deal found 11/10![Southwest logo]()
$417
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:14 am -
2 stops9h 56m
Sun 12/136:44 pm -
1 stop4h 21m
Deal found 11/13![American Airlines logo]()
$589
This Southwest deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm -
2 stops7h 50m
Mon 12/146:00 am -
1 stop8h 15m
Deal found 11/12![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/268:00 am -
1 stop5h 34m
Sat 1/307:15 am -
1 stop7h 04m
Deal found 11/11![United Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/83:00 pm -
1 stop7h 15m
Mon 1/112:10 pm -
2 stops7h 25m
Deal found 11/10![Southwest logo]()
$417
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:05 pm -
2 stops8h 31m
Sun 1/34:48 pm -
1 stop6h 20m
Deal found 11/13![American Airlines logo]()
$621
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:38 am -
1 stop5h 32m
Sun 1/36:00 am -
1 stop4h 53m
Deal found 11/13![Delta logo]()
$448
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/223:00 pm -
1 stop6h 44m
Fri 1/297:00 am -
1 stop7h 19m
Deal found 11/11![United Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/78:00 am -
2 stops7h 40m
Sun 1/106:30 am -
2 stops7h 40m
Deal found 11/8![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:23 pm -
2 stops7h 54m
Mon 12/141:57 pm -
2 stops9h 18m
Deal found 11/9![United Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:31 pm -
1 stop7h 05m
Wed 12/96:40 pm -
1 stop4h 50m
Deal found 11/9![American Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:00 am -
1 stop5h 22m
Mon 12/144:07 pm -
1 stop6h 14m
Deal found 11/9![United Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:56 pm -
1 stop4h 42m
Sat 12/194:03 pm -
1 stop6h 26m
Deal found 11/9![United Airlines logo]()
$474
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:25 pm -
1 stop7h 27m
Fri 11/275:10 am -
2 stops8h 18m
Deal found 11/9![American Airlines logo]()
$787
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated November 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated November 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:17 pm -
2 stops38h 21m
Fri 12/46:05 pm -
1 stop18h 04m
Deal found 11/9![Multiple Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
1 stop7h 15m
Sat 12/123:56 pm -
1 stop6h 25m
Deal found 11/10![United Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:20 am -
1 stop5h 48m
Fri 12/1811:50 am -
1 stop6h 16m
Deal found 11/9![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:09 am -
2 stops8h 43m
Wed 12/1611:50 am -
1 stop6h 18m
Deal found 11/9![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:09 am -
2 stops8h 43m
Tue 12/156:07 am -
2 stops10h 42m
Deal found 11/9![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:58 pm -
1 stop7h 27m
Sun 12/135:27 pm -
1 stop5h 11m
Deal found 11/10![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:56 pm -
1 stop6h 57m
Sat 12/196:05 pm -
1 stop5h 54m
Deal found 11/10![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:31 pm -
1 stop7h 30m
Sat 1/910:32 am -
1 stop6h 57m
Deal found 11/12![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:30 am -
2 stops7h 49m
Sat 1/96:02 am -
1 stop6h 40m
Deal found 11/10![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:43 pm -
1 stop4h 16m
Sat 12/196:33 pm -
1 stop4h 40m
Deal found 11/9![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:38 pm -
1 stop4h 21m
Wed 12/236:33 pm -
1 stop4h 40m
Deal found 11/10![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:15 pm -
1 stop5h 30m
Wed 1/64:00 pm -
1 stop5h 35m
Deal found 11/9![Southwest logo]()
$347
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated November 13, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated November 13, 2026.
This CheapOair deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:39 pm -
1 stop16h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Frontier logo]()
$150
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:49 am -
1 stop5h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![American Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Southwest logo]()
$204
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Southwest logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:07 am -
3 stops25h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Multiple Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:30 am -
1 stop5h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/511:46 am -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$332
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:00 am -
2 stops12h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:30 am -
1 stop7h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$362
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Southwest logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
3 stops14h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/35:00 am -
2 stops10h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$379
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated November 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $347 (Southwest) |
One-way from | $150 (CheapOair) |
Popular in | July |
Cheapest in | August |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 13, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 12/10
8:39 pm-1:23 pm
1 stop16h 44m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$150
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 12/24
6:00 am-2:25 pm
2 stops8h 25m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$204
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 12/25
7:00 am-2:25 pm
2 stops7h 25m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$219
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 12/10
9:07 am-10:33 am
3 stops25h 26m
New Orleans Louis Armstrong
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
Des MoinesLafayette
DSM Des Moines - LFT Lafayette Regional
DSMLFT
Des Moines
Mon 1/4
5:30 am-10:56 am
1 stop5h 26m
Lafayette Regional
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
Des MoinesMonroe
DSM Des Moines - MLU Monroe Huenefeld
DSMMLU
Des Moines
Tue 1/5
11:46 am-5:14 pm
1 stop5h 28m
Monroe Huenefeld
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
Des MoinesLafayette
DSM Des Moines - LFT Lafayette Regional
DSMLFT
Des Moines
Mon 1/4
5:00 am-5:41 pm
2 stops12h 41m
Lafayette Regional
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Mon 4/5
5:15 pm-10:01 pm
1 stop4h 46m
Baton Rouge Ryan
Sat 4/10
10:29 am-4:27 pm
1 stop5h 58m
$349
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Mon 12/14
8:00 am-3:15 pm
1 stop7h 15m
Baton Rouge Ryan
Fri 1/8
7:15 am-2:19 pm
1 stop7h 04m
$349
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Tue 12/15
3:31 pm-9:46 pm
1 stop6h 15m
Baton Rouge Ryan
Sat 1/9
4:42 pm-10:16 pm
1 stop5h 34m
$349
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-LFT
DSM-MLU
DSM-SHV
DSM-BTR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-LFT
DSM-MLU
DSM-SHV
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $379). Flying from Des Moines to Louisiana in July is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is typical for this route at the moment.
Des Moines to Louisiana flights typically cost between $324 and $516 in December.The cheapest round-trip price found within the last 5 days was $347 on Southwest (Dec 30-Jan 6).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 29 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated November 13, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on November 13, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$411 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$287 | Average$478 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$402 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$384 | FlexibilityNo cancel fee | On-time69% |