$125+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Aug 9 — Aug 161
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:59 am
DSM
- MSY
1 stop4h 32m
Delta
Sat 9/55:12 am
MSY
- DSM
1 stop5h 31m
Delta
Deal found 7/7![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:15 am
DSM
- MSY
1 stop4h 51m
United Airlines
Mon 8/2412:00 pm
MSY
- DSM
2 stops9h 23m
United Airlines
Deal found 7/8![United Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Mon 8/312:30 pm
MSY
- DSM
2 stops7h 40m
Southwest
Deal found 7/9![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- MSY
1 stop6h 00m
Southwest
Tue 8/181:55 pm
MSY
- DSM
2 stops8h 00m
Southwest
Deal found 7/7![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:10 am
DSM
- MSY
2 stops6h 45m
Southwest
Mon 8/245:30 am
MSY
- DSM
2 stops8h 15m
Southwest
Deal found 7/7![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:00 pm
DSM
- MSY
1 stop10h 20m
Southwest
Tue 10/137:00 am
MSY
- DSM
2 stops7h 20m
Southwest
Deal found 7/7![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:54 pm
DSM
- MSY
1 stop4h 41m
Delta
Tue 11/105:40 pm
MSY
- DSM
1 stop4h 49m
Delta
Deal found 7/8![Delta logo]()
$274
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Thu 8/272:00 pm
MSY
- DSM
2 stops8h 10m
Southwest
Deal found 7/7![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:00 pm
DSM
- MSY
1 stop10h 20m
Southwest
Mon 10/196:00 am
MSY
- DSM
1 stop12h 30m
Southwest
Deal found 7/7![Southwest logo]()
$276
This CheapOair deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:19 pm
DSM
- MSY
1 stop6h 32m
Frontier
Sun 8/239:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 7/6![Frontier logo]()
$278
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:59 am
DSM
- MSY
1 stop4h 20m
Delta
Fri 9/254:24 pm
MSY
- DSM
1 stop4h 47m
Delta
Deal found 7/8![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:00 am
DSM
- MSY
1 stop4h 55m
United Airlines
Sat 8/82:21 pm
MSY
- DSM
2 stops8h 39m
United Airlines
Deal found 7/8![United Airlines logo]()
$287
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:31 am
DSM
- MSY
1 stop6h 57m
Delta
Sat 9/124:21 pm
MSY
- DSM
1 stop4h 50m
Delta
Deal found 7/8![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:50 pm
DSM
- MSY
1 stop6h 00m
Southwest
Mon 8/313:00 pm
MSY
- DSM
2 stops7h 10m
Southwest
Deal found 7/9![Southwest logo]()
$254
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:15 am
DSM
- MSY
1 stop4h 51m
United Airlines
Mon 8/2412:00 pm
MSY
- DSM
2 stops9h 23m
United Airlines
Deal found 7/8![United Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:13 pm
DSM
- AEX
1 stop4h 01m
American Airlines
Sun 7/265:41 pm
AEX
- DSM
1 stop6h 17m
American Airlines
Deal found 7/6![American Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:40 pm
DSM
- MSY
2 stops7h 20m
Southwest
Sat 9/1210:15 am
MSY
- DSM
2 stops9h 10m
Southwest
Deal found 7/7![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Tue 8/182:05 pm
MSY
- DSM
2 stops7h 50m
Southwest
Deal found 7/7![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm
DSM
- BTR
2 stops7h 16m
Delta
Mon 8/243:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/10![Delta logo]()
$314
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:00 pm
DSM
- MSY
1 stop10h 20m
Southwest
Tue 10/137:00 am
MSY
- DSM
2 stops7h 20m
Southwest
Deal found 7/7![Southwest logo]()
$268
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:32 am
DSM
- MSY
2 stops11h 13m
United Airlines
Sat 9/125:05 am
MSY
- DSM
2 stops9h 15m
United Airlines
Deal found 7/8![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:41 am
DSM
- AEX
1 stop5h 18m
Delta
Tue 7/285:09 pm
AEX
- DSM
1 stop5h 20m
Delta
Deal found 7/9![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:48 pm
DSM
- BTR
1 stop5h 19m
American Airlines
Tue 8/46:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 7/5![American Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:54 pm
DSM
- MSY
1 stop4h 41m
Delta
Sun 10/185:30 am
MSY
- DSM
1 stop5h 12m
Delta
Deal found 7/9![Delta logo]()
$328
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:02 pm
DSM
- BTR
1 stop6h 26m
United Airlines
Sat 8/294:10 pm
BTR
- DSM
1 stop6h 20m
United Airlines
Deal found 7/6![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:59 am
DSM
- MSY
1 stop4h 32m
Delta
Thu 9/105:10 pm
MSY
- DSM
1 stop5h 19m
Delta
Deal found 7/9![Delta logo]()
$353
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:21 am
DSM
- AEX
2 stops9h 07m
United Airlines
Sat 10/319:45 am
AEX
- DSM
2 stops10h 44m
United Airlines
Deal found 7/7![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 am
DSM
- MSY
1 stop5h 45m
Southwest
Sat 8/227:15 am
MSY
- DSM
1 stop4h 15m
Southwest
Deal found 7/5![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:15 am
DSM
- AEX
2 stops10h 45m
United Airlines
Wed 10/289:45 am
AEX
- DSM
2 stops10h 44m
United Airlines
Deal found 7/6![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:54 pm
DSM
- MSY
1 stop5h 37m
Delta
Tue 10/136:30 am
MSY
- DSM
1 stop7h 39m
Delta
Deal found 7/7![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:15 am
DSM
- MSY
1 stop7h 15m
Southwest
Wed 8/266:00 am
MSY
- DSM
1 stop7h 55m
Southwest
Deal found 7/5![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:00 am
DSM
- AEX
2 stops7h 25m
United Airlines
Sun 7/264:00 pm
AEX
- DSM
1 stop6h 35m
United Airlines
Deal found 7/6![United Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
DSM
- AEX
2 stops9h 25m
United Airlines
Tue 7/289:43 am
AEX
- DSM
2 stops11h 39m
United Airlines
Deal found 7/9![United Airlines logo]()
$433
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated July 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:48 pm
DSM
- BTR
1 stop5h 19m
American Airlines
Mon 8/36:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 7/5![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:00 am
DSM
- MSY
1 stop4h 55m
United Airlines
Sat 8/82:21 pm
MSY
- DSM
2 stops8h 39m
United Airlines
Deal found 7/8![United Airlines logo]()
$287
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:20 am
DSM
- MSY
1 stop4h 31m
United Airlines
Sat 8/152:15 pm
MSY
- DSM
2 stops9h 29m
United Airlines
Deal found 7/9![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- MSY
1 stop6h 00m
Southwest
Tue 8/181:55 pm
MSY
- DSM
2 stops8h 00m
Southwest
Deal found 7/7![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:02 pm
DSM
- MSY
1 stop5h 01m
United Airlines
Mon 8/247:00 am
MSY
- DSM
1 stop5h 20m
United Airlines
Deal found 7/7![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:10 am
DSM
- MSY
2 stops6h 45m
Southwest
Mon 8/245:30 am
MSY
- DSM
2 stops8h 15m
Southwest
Deal found 7/7![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Thu 8/272:00 pm
MSY
- DSM
2 stops8h 10m
Southwest
Deal found 7/7![Southwest logo]()
$275
This CheapOair deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:19 pm
DSM
- MSY
1 stop6h 32m
Frontier
Sun 8/239:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 7/6![Frontier logo]()
$278
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm
DSM
- BTR
2 stops7h 16m
Delta
Mon 8/243:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/10![Delta logo]()
$314
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:54 pm
DSM
- MSY
1 stop5h 39m
Delta
Fri 8/2811:04 am
MSY
- DSM
1 stop6h 46m
Delta
Deal found 7/7![Delta logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- MSY
1 stop31h 10m
Multiple Airlines
Sun 8/307:11 pm
MSY
- DSM
2 stops18h 23m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Mon 8/312:30 pm
MSY
- DSM
2 stops7h 40m
Southwest
Deal found 7/9![Southwest logo]()
$259
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:20 am
DSM
- MSY
1 stop6h 54m
United Airlines
Deal found 7/8![United Airlines logo]()
$125
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 am
DSM
- MSY
2 stops8h 50m
Southwest
Deal found 7/7![Southwest logo]()
$130
This Frontier deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:19 pm
DSM
- MSY
1 stop6h 32m
Frontier
Deal found 7/7![Frontier logo]()
$135
This Trip.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Deal found 7/8![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am
DSM
- MSY
2 stops33h 29m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:57 pm
DSM
- MSY
2 stops23h 27m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am
DSM
- MSY
2 stops32h 03m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- MSY
2 stops16h 08m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:18 pm
DSM
- MSY
3 stops26h 49m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$201
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:13 am
DSM
- MSY
1 stop7h 49m
United Airlines
Deal found 7/8![United Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:20 am
DSM
- BTR
1 stop7h 09m
United Airlines
Deal found 7/6![United Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:14 pm
DSM
- AEX
1 stop7h 00m
American Airlines
Deal found 7/8![American Airlines logo]()
$419
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Delta) |
One-way from | $125 (United Airlines) |
Popular in | July |
Cheapest in | September |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 9/9
11:31 am-6:28 pm
1 stop6h 57m
New Orleans Louis Armstrong
Sat 9/12
4:21 pm-9:11 pm
1 stop4h 50m
$249
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Mon 8/24
3:50 pm-9:50 pm
1 stop6h 00m
New Orleans Louis Armstrong
Mon 8/31
3:00 pm-10:10 pm
2 stops7h 10m
$254
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 8/19
6:15 am-11:06 am
1 stop4h 51m
New Orleans Louis Armstrong
Mon 8/24
12:00 pm-9:23 pm
2 stops9h 23m
$254
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 9/9
2:40 pm-10:00 pm
2 stops7h 20m
New Orleans Louis Armstrong
Sat 9/12
10:15 am-7:25 pm
2 stops9h 10m
$259
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 8/13
3:50 pm-10:40 pm
2 stops6h 50m
New Orleans Louis Armstrong
Tue 8/18
2:05 pm-9:55 pm
2 stops7h 50m
$267
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/8
2:00 pm-12:20 am
1 stop10h 20m
New Orleans Louis Armstrong
Tue 10/13
7:00 am-2:20 pm
2 stops7h 20m
$268
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Fri 8/21
2:45 pm-10:01 pm
2 stops7h 16m
Baton Rouge Ryan
Mon 8/24
3:57 pm-10:37 pm
1 stop6h 40m
$314
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Fri 7/24
5:41 am-10:59 am
1 stop5h 18m
Alexandria
Tue 7/28
5:09 pm-10:29 pm
1 stop5h 20m
$328
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/15
6:54 pm-11:35 pm
1 stop4h 41m
New Orleans Louis Armstrong
Sun 10/18
5:30 am-10:42 am
1 stop5h 12m
$328
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 9/9
11:32 am-10:45 pm
2 stops11h 13m
New Orleans Louis Armstrong
Sat 9/12
5:05 am-2:20 pm
2 stops9h 15m
$339
Showing 1-10 of 33 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $164). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 68 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated July 10, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on July 10, 2026.
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$426 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$409 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$270 | Average$388 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |