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$149+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated September 17, 2025.

Round-trip from

$228
(Kiwi.com)

One-way from

$149
(United Airlines)

Popular in

May

Cheapest in

November

Average price

$371
From Des Moines to Louisiana
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One-way flight from Des Moines to Louisiana
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Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:32 pmDSM - MSY
1 stop28h 28mMultiple Airlines
Thu 11/66:15 amMSY - DSM
1 stop13h 58mMultiple Airlines
Deal found 9/15$228
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:15 pmDSM - BTR
1 stop7h 37mDelta
Sat 12/136:00 amBTR - DSM
1 stop7h 30mDelta
Deal found 9/16$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:05 amDSM - BTR
2 stops8h 50mDelta
Tue 10/213:40 pmBTR - DSM
1 stop6h 50mDelta
Deal found 9/15$254
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:15 amDSM - BTR
1 stop6h 55mUnited Airlines
Sat 10/44:05 pmBTR - DSM
1 stop6h 23mUnited Airlines
Deal found 9/15$259
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:32 pmDSM - MSY
2 stops26h 34mFrontier
Sun 11/26:01 pmMSY - DSM
2 stops19h 46mFrontier
Deal found 9/16$262
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:37 pmDSM - MSY
1 stop27h 40mMultiple Airlines
Thu 10/236:34 pmMSY - DSM
1 stop22h 25mMultiple Airlines
Deal found 9/16$264
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:37 pmDSM - MSY
1 stop27h 40mMultiple Airlines
Sat 10/187:55 pmMSY - DSM
1 stop13h 56mMultiple Airlines
Deal found 9/16$275
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/22:16 pmDSM - BTR
1 stop5h 50mAmerican Airlines
Fri 11/145:30 amBTR - DSM
1 stop5h 10mAmerican Airlines
Deal found 9/15$279
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:17 pmDSM - BTR
1 stop5h 40mDelta
Mon 11/246:00 amBTR - DSM
2 stops10h 19mDelta
Deal found 9/17$284
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/162:37 pmDSM - MSY
2 stops38h 54mMultiple Airlines
Thu 10/236:34 pmMSY - DSM
1 stop22h 25mMultiple Airlines
Deal found 9/16$289
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:13 pmDSM - MSY
1 stop6h 04mDelta
Tue 10/216:20 amMSY - DSM
1 stop7h 08mDelta
Deal found 9/15$297
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/22:16 pmDSM - BTR
1 stop5h 50mAmerican Airlines
Tue 11/254:25 pmBTR - DSM
1 stop6h 28mAmerican Airlines
Deal found 9/15$309

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Des Moines

Fly to

Louisiana

Route

Depart

Return

Price

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Wed 12/10

2:15 pm-7:56 pm

1 stop5h 41m

Baton Rouge Ryan

Sat 12/13

6:00 am-1:30 pm

1 stop7h 30m

$249

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 10/14

2:13 pm-9:47 pm

1 stop7h 34m

Baton Rouge Ryan

Tue 10/21

3:40 pm-10:30 pm

1 stop6h 50m

$249

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 9/30

6:15 am-1:10 pm

1 stop6h 55m

Baton Rouge Ryan

Sat 10/4

4:05 pm-10:28 pm

1 stop6h 23m

$259

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Thu 10/2

4:04 pm-10:44 pm

1 stop6h 40m

Baton Rouge Ryan

Mon 10/6

6:21 pm-10:56 pm

1 stop4h 35m

$259

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Thu 10/30

2:32 pm-7:00 pm

1 stop28h 28m

New Orleans Louis Armstrong

Sun 11/2

6:01 pm-1:47 pm

2 stops19h 46m

$269

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 10/15

2:37 pm-6:17 pm

1 stop27h 40m

New Orleans Louis Armstrong

Sat 10/18

7:55 pm-9:51 am

1 stop13h 56m

$275

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Thu 11/20

2:17 pm-7:57 pm

1 stop5h 40m

Baton Rouge Ryan

Mon 11/24

6:00 am-10:42 am

1 stop4h 42m

$279

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Tue 10/14

6:07 pm-12:04 am

1 stop5h 57m

New Orleans Louis Armstrong

Tue 10/21

3:56 pm-11:16 pm

1 stop7h 20m

$297

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Tue 10/14

2:13 pm-8:17 pm

1 stop6h 04m

New Orleans Louis Armstrong

Tue 10/21

6:20 am-1:28 pm

1 stop7h 08m

$297

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 11/1

3:15 pm-10:26 pm

1 stop7h 11m

New Orleans Louis Armstrong

Wed 11/5

2:35 pm-8:45 pm

1 stop6h 10m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 21 results
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Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $256). Flying from Des Moines to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LA?

Find hourly flight availability from Des Moines to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Louisiana as you normally would.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 5h 41m. The distance between Des Moines and Louisiana is about 773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Louisiana one-way?

    One-way options have recently been found by users for as low as $149 on United Airlines. Other airlines that offer cheap prices include American Airlines from $149 and Southwest from $154 one-way.

  • What are the most popular routes from Des Moines to Louisiana?

    Most travelers choose Des Moines - New Orleans Louis Armstrong, Des Moines - Baton Rouge Ryan or Des Moines - Alexandria when deciding on the best route from Des Moines to Louisiana.

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $256). Flying from Des Moines to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$398FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$414FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$296Average$405FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$331Average$427FlexibilityNo cancel feeOn-time69%

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