$130+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Jul 26 — Aug 21
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.
This Frontier deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Thu 8/139:48 pm
MSY
- DSM
1 stop15h 46m
Frontier
Deal found 6/23![Frontier logo]()
$264
This CheapOair deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Thu 8/209:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 6/23![Frontier logo]()
$268
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:48 pm
DSM
- BTR
1 stop5h 19m
American Airlines
Tue 8/411:16 am
BTR
- DSM
1 stop4h 44m
American Airlines
Deal found 6/25![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:34 pm
DSM
- AEX
1 stop7h 00m
Delta
Mon 10/511:50 am
AEX
- DSM
1 stop6h 19m
Delta
Deal found 6/23![Delta logo]()
$312
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:13 pm
DSM
- MSY
1 stop6h 46m
American Airlines
Sat 8/156:50 pm
MSY
- DSM
1 stop5h 45m
American Airlines
Deal found 6/24![American Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:55 am
DSM
- MSY
1 stop5h 19m
American Airlines
Sat 9/56:00 pm
MSY
- DSM
1 stop5h 16m
American Airlines
Deal found 6/24![American Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:15 pm
DSM
- AEX
1 stop7h 23m
Delta
Tue 10/2711:27 am
AEX
- DSM
2 stops9h 25m
Delta
Deal found 6/23![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 am
DSM
- MSY
2 stops8h 50m
Southwest
Sat 8/157:15 am
MSY
- DSM
1 stop4h 15m
Southwest
Deal found 6/25![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:41 am
DSM
- BTR
1 stop7h 06m
Delta
Wed 8/56:07 am
BTR
- DSM
1 stop4h 36m
Delta
Deal found 6/23![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:10 am
DSM
- MSY
2 stops7h 55m
Southwest
Tue 9/1512:45 pm
MSY
- DSM
2 stops8h 15m
Southwest
Deal found 6/25![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
DSM
- BTR
1 stop6h 09m
American Airlines
Mon 7/132:12 pm
BTR
- DSM
1 stop4h 21m
American Airlines
Deal found 6/23![American Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- MSY
1 stop31h 43m
Multiple Airlines
Thu 8/139:48 pm
MSY
- DSM
1 stop15h 46m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$342
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 26, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 26, 2026.
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:34 pm
DSM
- AEX
1 stop7h 00m
Delta
Mon 10/511:50 am
AEX
- DSM
1 stop6h 19m
Delta
Deal found 6/23![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:10 am
DSM
- MSY
2 stops7h 55m
Southwest
Tue 9/157:20 am
MSY
- DSM
1 stop4h 30m
Southwest
Deal found 6/25![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:37 am
DSM
- AEX
2 stops10h 21m
United Airlines
Wed 11/184:06 pm
AEX
- DSM
1 stop6h 19m
United Airlines
Deal found 6/23![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:56 pm
DSM
- MSY
1 stop5h 42m
American Airlines
Sun 10/46:05 am
MSY
- DSM
1 stop7h 54m
American Airlines
Deal found 6/26![American Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:11 pm
DSM
- MSY
1 stop7h 26m
Delta
Tue 9/155:15 am
MSY
- DSM
1 stop5h 31m
Delta
Deal found 6/25![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/812:10 pm
DSM
- MSY
2 stops7h 40m
Southwest
Sat 8/157:15 am
MSY
- DSM
1 stop4h 15m
Southwest
Deal found 6/24![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:41 am
DSM
- BTR
1 stop7h 06m
Delta
Wed 8/56:07 am
BTR
- DSM
1 stop4h 36m
Delta
Deal found 6/24![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 am
DSM
- BTR
1 stop7h 01m
United Airlines
Sat 8/297:15 am
BTR
- DSM
1 stop6h 59m
United Airlines
Deal found 6/25![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:40 am
DSM
- MSY
1 stop5h 35m
Southwest
Sun 11/85:50 am
MSY
- DSM
1 stop7h 20m
Southwest
Deal found 6/24![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/102:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Tue 7/1410:25 am
BTR
- DSM
2 stops10h 24m
Delta
Deal found 6/25![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:12 am
DSM
- BTR
1 stop5h 46m
American Airlines
Wed 8/58:10 am
BTR
- DSM
2 stops11h 03m
American Airlines
Deal found 6/21![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
DSM
- AEX
2 stops9h 30m
United Airlines
Mon 10/54:05 pm
AEX
- DSM
1 stop6h 10m
United Airlines
Deal found 6/23![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:40 pm
DSM
- MSY
1 stop7h 15m
Southwest
Tue 8/42:05 pm
MSY
- DSM
2 stops7h 50m
Southwest
Deal found 6/22![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:12 am
DSM
- BTR
1 stop5h 31m
American Airlines
Mon 8/36:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 6/24![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:56 pm
DSM
- MSY
1 stop6h 41m
United Airlines
Wed 11/185:32 pm
MSY
- DSM
1 stop4h 53m
United Airlines
Deal found 6/25![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:15 pm
DSM
- MSY
1 stop6h 27m
Delta
Sun 11/155:30 am
MSY
- DSM
1 stop4h 48m
Delta
Deal found 6/21![Delta logo]()
$381
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 am
DSM
- MSY
1 stop4h 51m
United Airlines
Wed 8/267:00 am
MSY
- DSM
1 stop5h 20m
United Airlines
Deal found 6/22![United Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:21 pm
DSM
- BTR
2 stops8h 07m
United Airlines
Tue 8/187:15 am
BTR
- DSM
2 stops9h 04m
United Airlines
Deal found 6/23![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Mon 8/36:07 am
BTR
- DSM
1 stop4h 36m
Delta
Deal found 6/21![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:41 am
DSM
- BTR
1 stop7h 06m
Delta
Sun 7/124:00 pm
BTR
- DSM
1 stop6h 29m
Delta
Deal found 6/23![Delta logo]()
$399
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated June 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated June 26, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 pm
DSM
- BTR
1 stop4h 55m
Delta
Fri 7/104:00 pm
BTR
- DSM
1 stop6h 29m
Delta
Deal found 6/22![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:23 am
DSM
- BTR
1 stop5h 35m
American Airlines
Sat 8/16:47 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 6/23![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:12 am
DSM
- BTR
1 stop5h 31m
American Airlines
Mon 8/36:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 6/25![American Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:41 am
DSM
- BTR
1 stop7h 06m
Delta
Wed 8/56:07 am
BTR
- DSM
1 stop4h 36m
Delta
Deal found 6/23![Delta logo]()
$324
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
DSM
- BTR
1 stop6h 09m
American Airlines
Mon 7/132:12 pm
BTR
- DSM
1 stop4h 21m
American Airlines
Deal found 6/23![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/102:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Tue 7/1410:25 am
BTR
- DSM
2 stops10h 24m
Delta
Deal found 6/25![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:33 pm
DSM
- MSY
1 stop5h 14m
American Airlines
Mon 7/2012:22 pm
MSY
- DSM
1 stop6h 11m
American Airlines
Deal found 6/24![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:13 pm
DSM
- MSY
1 stop4h 45m
American Airlines
Sun 7/1911:20 am
MSY
- DSM
1 stop7h 13m
American Airlines
Deal found 6/24![American Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:48 pm
DSM
- BTR
1 stop5h 19m
American Airlines
Tue 8/411:16 am
BTR
- DSM
1 stop4h 44m
American Airlines
Deal found 6/25![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:48 pm
DSM
- BTR
1 stop5h 19m
American Airlines
Tue 8/46:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 6/25![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:00 am
DSM
- MSY
1 stop4h 55m
United Airlines
Tue 8/45:35 pm
MSY
- DSM
1 stop5h 21m
United Airlines
Deal found 6/22![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:40 pm
DSM
- MSY
1 stop7h 15m
Southwest
Tue 8/42:05 pm
MSY
- DSM
2 stops7h 50m
Southwest
Deal found 6/22![Southwest logo]()
$367
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 26, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 26, 2026.
This Frontier deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Deal found 6/25![Frontier logo]()
$130
This Frontier deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Deal found 6/23![Frontier logo]()
$135
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/102:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Deal found 6/24![Frontier logo]()
$155
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Deal found 6/24![Frontier logo]()
$185
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:50 pm
DSM
- MSY
2 stops6h 50m
Southwest
Deal found 6/25![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:48 pm
DSM
- BTR
1 stop6h 09m
American Airlines
Deal found 6/22![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:30 am
DSM
- MSY
1 stop6h 37m
Delta
Deal found 6/23![Delta logo]()
$244
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:45 pm
DSM
- MSY
2 stops7h 00m
Southwest
Deal found 6/24![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:24 pm
DSM
- MSY
2 stops8h 02m
United Airlines
Deal found 6/23![United Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:20 am
DSM
- BTR
1 stop5h 00m
United Airlines
Deal found 6/24![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
DSM
- BTR
2 stops9h 09m
Delta
Deal found 6/24![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
DSM
- MSY
2 stops9h 12m
American Airlines
Deal found 6/24![American Airlines logo]()
$326
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated June 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $264 (Frontier) |
One-way from | $135 (Frontier) |
Popular in | July |
Cheapest in | September |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Fri 10/2
2:34 pm-9:34 pm
1 stop7h 00m
Alexandria
Mon 10/5
11:50 am-6:09 pm
1 stop6h 19m
$312
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/8
4:11 pm-11:37 pm
1 stop7h 26m
New Orleans Louis Armstrong
Tue 9/15
5:15 am-10:46 am
1 stop5h 31m
$317
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/8
6:10 am-2:05 pm
2 stops7h 55m
New Orleans Louis Armstrong
Tue 9/15
7:20 am-11:50 am
1 stop4h 30m
$322
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 8/8
12:10 pm-7:50 pm
2 stops7h 40m
New Orleans Louis Armstrong
Sat 8/15
7:15 am-11:30 am
1 stop4h 15m
$322
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Thu 7/9
5:41 am-12:47 pm
1 stop7h 06m
Baton Rouge Ryan
Wed 8/5
6:07 am-10:43 am
1 stop4h 36m
$324
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Fri 7/10
2:25 pm-9:56 pm
1 stop7h 31m
Baton Rouge Ryan
Tue 7/14
10:25 am-8:49 pm
2 stops10h 24m
$344
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 10/31
5:40 am-11:15 am
1 stop5h 35m
New Orleans Louis Armstrong
Sun 11/8
5:50 am-1:10 pm
1 stop7h 20m
$362
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Fri 7/31
4:40 pm-11:55 pm
1 stop7h 15m
New Orleans Louis Armstrong
Tue 8/4
2:05 pm-9:55 pm
2 stops7h 50m
$367
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 11/12
2:15 pm-8:42 pm
1 stop6h 27m
New Orleans Louis Armstrong
Sun 11/15
5:30 am-10:18 am
1 stop4h 48m
$381
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Sat 11/14
9:37 am-7:58 pm
2 stops10h 21m
Alexandria
Wed 11/18
4:06 pm-10:25 pm
1 stop6h 19m
$384
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-BTR
DSM-MSY
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-BTR
DSM-MSY
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $164). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 71 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated June 26, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on June 26, 2026.
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$425 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$388 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |