$135+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Apr 23 — Apr 301
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:44 pm
DSM
- MSY
1 stop4h 46m
Delta
Tue 5/1212:27 pm
MSY
- DSM
1 stop4h 39m
Delta
Deal found 3/20![Delta logo]()
$291
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:55 am
DSM
- MSY
1 stop7h 10m
Frontier
Thu 3/263:36 pm
MSY
- DSM
1 stop27h 40m
Frontier
Deal found 3/20![Frontier logo]()
$296
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:05 am
DSM
- MSY
1 stop7h 29m
American Airlines
Mon 5/117:37 pm
MSY
- DSM
1 stop4h 22m
American Airlines
Deal found 3/23![American Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:45 am
DSM
- MSY
1 stop25h 20m
Multiple Airlines
Wed 5/204:15 pm
MSY
- DSM
2 stops30h 16m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:20 am
DSM
- MSY
1 stop7h 52m
United Airlines
Wed 4/155:25 pm
MSY
- DSM
1 stop5h 18m
United Airlines
Deal found 3/19![United Airlines logo]()
$306
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Sun 5/109:55 pm
MSY
- DSM
1 stop15h 36m
Frontier
Deal found 3/23![Frontier logo]()
$312
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 am
DSM
- MSY
2 stops9h 25m
Southwest
Wed 4/222:50 pm
MSY
- DSM
2 stops7h 20m
Southwest
Deal found 3/20![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:41 pm
DSM
- MSY
1 stop5h 13m
Delta
Thu 5/146:20 am
MSY
- DSM
1 stop4h 48m
Delta
Deal found 3/23![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:56 am
DSM
- MSY
1 stop4h 24m
Delta
Thu 5/146:20 am
MSY
- DSM
1 stop7h 17m
Delta
Deal found 3/19![Delta logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:48 pm
DSM
- MSY
2 stops29h 56m
Multiple Airlines
Thu 4/96:00 am
MSY
- DSM
1 stop16h 06m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:44 pm
DSM
- BTR
1 stop7h 12m
Delta
Tue 5/123:48 pm
BTR
- DSM
1 stop6h 44m
Delta
Deal found 3/21![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:20 pm
DSM
- BTR
1 stop4h 43m
Delta
Tue 4/74:00 pm
BTR
- DSM
1 stop6h 38m
Delta
Deal found 3/19![Delta logo]()
$339
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:21 pm
DSM
- MSY
2 stops8h 08m
United Airlines
Wed 4/159:49 am
MSY
- DSM
1 stop4h 33m
United Airlines
Deal found 3/19![United Airlines logo]()
$311
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Sun 5/109:55 pm
MSY
- DSM
1 stop15h 36m
Frontier
Deal found 3/23![Frontier logo]()
$312
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:33 pm
DSM
- BTR
1 stop7h 27m
Delta
Tue 6/26:03 am
BTR
- DSM
1 stop7h 34m
Delta
Deal found 3/21![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:00 am
DSM
- BTR
2 stops10h 58m
American Airlines
Tue 4/76:32 pm
BTR
- DSM
1 stop4h 44m
American Airlines
Deal found 3/19![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
DSM
- MSY
2 stops9h 25m
Southwest
Mon 5/116:20 am
MSY
- DSM
2 stops6h 50m
Southwest
Deal found 3/23![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:20 pm
DSM
- BTR
1 stop4h 43m
Delta
Tue 4/74:00 pm
BTR
- DSM
1 stop6h 38m
Delta
Deal found 3/19![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:18 pm
DSM
- AEX
1 stop5h 38m
American Airlines
Sat 4/116:26 pm
AEX
- DSM
1 stop5h 33m
American Airlines
Deal found 3/23![American Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:20 am
DSM
- MSY
1 stop5h 55m
Southwest
Sat 6/275:45 am
MSY
- DSM
1 stop5h 50m
Southwest
Deal found 3/21![Southwest logo]()
$394
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
DSM
- AEX
2 stops9h 28m
United Airlines
Tue 8/259:43 am
AEX
- DSM
1 stop4h 34m
United Airlines
Deal found 3/19![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:15 am
DSM
- AEX
2 stops9h 58m
Delta
Wed 4/85:00 pm
AEX
- DSM
1 stop5h 38m
Delta
Deal found 3/20![Delta logo]()
$394
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:48 pm
DSM
- BTR
1 stop6h 11m
American Airlines
Tue 6/211:16 am
BTR
- DSM
1 stop4h 47m
American Airlines
Deal found 3/19![American Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:20 pm
DSM
- MSY
1 stop7h 50m
Southwest
Fri 5/152:45 pm
MSY
- DSM
2 stops8h 20m
Southwest
Deal found 3/23![Southwest logo]()
$410
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:00 am
DSM
- BTR
2 stops10h 34m
United Airlines
Sat 8/14:09 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 3/21![United Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:15 pm
DSM
- MSY
1 stop6h 24m
Delta
Mon 9/77:30 am
MSY
- DSM
1 stop5h 52m
Delta
Deal found 3/20![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:35 pm
DSM
- BTR
2 stops9h 11m
United Airlines
Tue 6/24:09 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 3/19![United Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:25 am
DSM
- MSY
2 stops9h 25m
Southwest
Sun 5/246:50 am
MSY
- DSM
1 stop5h 45m
Southwest
Deal found 3/22![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:20 am
DSM
- BTR
1 stop7h 13m
United Airlines
Wed 4/84:08 pm
BTR
- DSM
1 stop6h 35m
United Airlines
Deal found 3/19![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:20 am
DSM
- MSY
1 stop4h 52m
United Airlines
Thu 4/162:23 pm
MSY
- DSM
1 stop6h 11m
United Airlines
Deal found 3/20![United Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:26 am
DSM
- AEX
2 stops10h 49m
Delta
Mon 6/811:46 am
AEX
- DSM
1 stop6h 08m
Delta
Deal found 3/21![Delta logo]()
$844
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated March 24, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated March 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:52 pm
DSM
- BTR
1 stop7h 44m
American Airlines
Tue 3/315:00 am
BTR
- DSM
1 stop5h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:20 pm
DSM
- BTR
1 stop4h 43m
Delta
Tue 4/74:00 pm
BTR
- DSM
1 stop6h 38m
Delta
Deal found 3/19![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:00 am
DSM
- BTR
2 stops10h 58m
American Airlines
Tue 4/76:32 pm
BTR
- DSM
1 stop4h 44m
American Airlines
Deal found 3/19![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:33 am
DSM
- AEX
1 stop4h 40m
Delta
Wed 4/86:00 am
AEX
- DSM
1 stop4h 48m
Delta
Deal found 3/20![Delta logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:48 pm
DSM
- MSY
2 stops29h 56m
Multiple Airlines
Thu 4/96:00 am
MSY
- DSM
1 stop16h 06m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:00 pm
DSM
- MSY
1 stop6h 20m
American Airlines
Mon 4/137:37 pm
MSY
- DSM
1 stop4h 22m
American Airlines
Deal found 3/20![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:20 am
DSM
- MSY
1 stop7h 52m
United Airlines
Wed 4/155:25 pm
MSY
- DSM
1 stop5h 18m
United Airlines
Deal found 3/19![United Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/112:16 pm
DSM
- MSY
2 stops8h 31m
American Airlines
Wed 4/159:15 am
MSY
- DSM
2 stops7h 16m
American Airlines
Deal found 3/19![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1112:05 pm
DSM
- MSY
1 stop10h 05m
Southwest
Wed 4/155:35 pm
MSY
- DSM
1 stop4h 35m
Southwest
Deal found 3/23![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 am
DSM
- MSY
2 stops9h 25m
Southwest
Wed 4/222:50 pm
MSY
- DSM
2 stops7h 20m
Southwest
Deal found 3/20![Southwest logo]()
$316
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:02 pm
DSM
- MSY
1 stop7h 17m
American Airlines
Tue 4/215:30 am
MSY
- DSM
1 stop5h 56m
American Airlines
Deal found 3/23![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:44 pm
DSM
- MSY
1 stop5h 24m
Delta
Tue 4/211:21 pm
MSY
- DSM
1 stop4h 24m
Delta
Deal found 3/20![Delta logo]()
$349
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
This Priceline deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Deal found 3/23![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:48 pm
DSM
- MSY
2 stops28h 11m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$149
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/152:15 pm
DSM
- MSY
1 stop6h 24m
Delta
Deal found 3/22![Delta logo]()
$204
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:41 pm
DSM
- MSY
2 stops7h 18m
American Airlines
Deal found 3/22![American Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:45 am
DSM
- BTR
1 stop7h 05m
Delta
Deal found 3/20![Delta logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:18 pm
DSM
- MSY
3 stops32h 30m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:44 pm
DSM
- BTR
1 stop7h 12m
Delta
Deal found 3/19![Delta logo]()
$328
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:35 am
DSM
- AEX
1 stop5h 28m
Delta
Deal found 3/23![Delta logo]()
$382
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated March 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (Delta) |
One-way from | $135 (Priceline) |
Popular in | May |
Cheapest in | September |
Average price | $432 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 4/11
3:21 pm-11:29 pm
2 stops8h 08m
New Orleans Louis Armstrong
Wed 4/15
9:49 am-2:22 pm
1 stop4h 33m
$311
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Fri 5/8
2:16 pm-9:10 pm
1 stop6h 54m
New Orleans Louis Armstrong
Sun 5/10
9:55 pm-1:31 pm
1 stop15h 36m
$312
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Thu 5/28
2:33 pm-10:00 pm
1 stop7h 27m
Baton Rouge Ryan
Tue 6/2
6:03 am-1:37 pm
1 stop7h 34m
$329
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Fri 4/3
5:20 pm-10:03 pm
1 stop4h 43m
Baton Rouge Ryan
Tue 4/7
4:00 pm-10:38 pm
1 stop6h 38m
$339
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Fri 4/3
5:00 am-3:58 pm
2 stops10h 58m
Baton Rouge Ryan
Tue 4/7
6:32 pm-11:16 pm
1 stop4h 44m
$344
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 5/9
6:40 am-4:05 pm
2 stops9h 25m
New Orleans Louis Armstrong
Mon 5/11
6:20 am-1:10 pm
2 stops6h 50m
$373
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Tue 4/7
12:18 pm-5:56 pm
1 stop5h 38m
Alexandria
Sat 4/11
6:26 pm-11:59 pm
1 stop5h 33m
$388
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 6/24
5:20 am-11:15 am
1 stop5h 55m
New Orleans Louis Armstrong
Sat 6/27
5:45 am-11:35 am
1 stop5h 50m
$394
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Sat 4/4
6:15 am-4:13 pm
2 stops9h 58m
Alexandria
Wed 4/8
5:00 pm-10:38 pm
1 stop5h 38m
$394
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Sat 8/22
6:00 am-3:28 pm
2 stops9h 28m
Alexandria
Tue 8/25
9:43 am-2:17 pm
1 stop4h 34m
$404
Showing 1-10 of 25 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $191). Flying from Des Moines to Louisiana in December is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated March 24, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on March 24, 2026.
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Des Moines to Louisiana flights
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Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$466 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$387 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |