Louisiana

$135+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Apr 23 — Apr 301
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Cheap flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:44 pm
DSM
-
MSY
1 stop4h 46m
Delta
Tue 5/1212:27 pm
MSY
-
DSM
1 stop4h 39m
Delta
Deal found 3/20$291
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:55 am
DSM
-
MSY
1 stop7h 10m
Frontier
Thu 3/263:36 pm
MSY
-
DSM
1 stop27h 40m
Frontier
Deal found 3/20$296
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:05 am
DSM
-
MSY
1 stop7h 29m
American Airlines
Mon 5/117:37 pm
MSY
-
DSM
1 stop4h 22m
American Airlines
Deal found 3/23$297
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:45 am
DSM
-
MSY
1 stop25h 20m
Multiple Airlines
Wed 5/204:15 pm
MSY
-
DSM
2 stops30h 16m
Multiple Airlines
Deal found 3/23$304
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:20 am
DSM
-
MSY
1 stop7h 52m
United Airlines
Wed 4/155:25 pm
MSY
-
DSM
1 stop5h 18m
United Airlines
Deal found 3/19$306
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
-
MSY
1 stop6h 54m
Frontier
Sun 5/109:55 pm
MSY
-
DSM
1 stop15h 36m
Frontier
Deal found 3/23$312
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 am
DSM
-
MSY
2 stops9h 25m
Southwest
Wed 4/222:50 pm
MSY
-
DSM
2 stops7h 20m
Southwest
Deal found 3/20$316
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:41 pm
DSM
-
MSY
1 stop5h 13m
Delta
Thu 5/146:20 am
MSY
-
DSM
1 stop4h 48m
Delta
Deal found 3/23$317
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:56 am
DSM
-
MSY
1 stop4h 24m
Delta
Thu 5/146:20 am
MSY
-
DSM
1 stop7h 17m
Delta
Deal found 3/19$321
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:48 pm
DSM
-
MSY
2 stops29h 56m
Multiple Airlines
Thu 4/96:00 am
MSY
-
DSM
1 stop16h 06m
Multiple Airlines
Deal found 3/23$326
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:44 pm
DSM
-
BTR
1 stop7h 12m
Delta
Tue 5/123:48 pm
BTR
-
DSM
1 stop6h 44m
Delta
Deal found 3/21$329
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:20 pm
DSM
-
BTR
1 stop4h 43m
Delta
Tue 4/74:00 pm
BTR
-
DSM
1 stop6h 38m
Delta
Deal found 3/19$339

Find flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated March 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(Delta)

One-way from

$135
(Priceline)

Popular in

May

Cheapest in

September

Average price

$432
Provider with most accurate pricing for Des Moines-New Orleans Louis Armstrong flight deals.
Provider most trusted by Cheapflights users for Des Moines-New Orleans Louis Armstrong flights.
From Des Moines to Louisiana
One-way flight from Des Moines to Louisiana
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 4/11

3:21 pm-11:29 pm

2 stops8h 08m

New Orleans Louis Armstrong

Wed 4/15

9:49 am-2:22 pm

1 stop4h 33m

$311

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Fri 5/8

2:16 pm-9:10 pm

1 stop6h 54m

New Orleans Louis Armstrong

Sun 5/10

9:55 pm-1:31 pm

1 stop15h 36m

$312

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Thu 5/28

2:33 pm-10:00 pm

1 stop7h 27m

Baton Rouge Ryan

Tue 6/2

6:03 am-1:37 pm

1 stop7h 34m

$329

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Fri 4/3

5:20 pm-10:03 pm

1 stop4h 43m

Baton Rouge Ryan

Tue 4/7

4:00 pm-10:38 pm

1 stop6h 38m

$339

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Fri 4/3

5:00 am-3:58 pm

2 stops10h 58m

Baton Rouge Ryan

Tue 4/7

6:32 pm-11:16 pm

1 stop4h 44m

$344

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 5/9

6:40 am-4:05 pm

2 stops9h 25m

New Orleans Louis Armstrong

Mon 5/11

6:20 am-1:10 pm

2 stops6h 50m

$373

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Tue 4/7

12:18 pm-5:56 pm

1 stop5h 38m

Alexandria

Sat 4/11

6:26 pm-11:59 pm

1 stop5h 33m

$388

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 6/24

5:20 am-11:15 am

1 stop5h 55m

New Orleans Louis Armstrong

Sat 6/27

5:45 am-11:35 am

1 stop5h 50m

$394

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Sat 4/4

6:15 am-4:13 pm

2 stops9h 58m

Alexandria

Wed 4/8

5:00 pm-10:38 pm

1 stop5h 38m

$394

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Sat 8/22

6:00 am-3:28 pm

2 stops9h 28m

Alexandria

Tue 8/25

9:43 am-2:17 pm

1 stop4h 34m

$404

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 25 resultsSorted by cheapest first
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Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $191). Flying from Des Moines to Louisiana in December is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated March 24, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 6h 54m. The distance between Des Moines and Louisiana is about 820 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Louisiana one-way?

    One-way options have recently been found by users for as low as $118 on Delta. Other airlines that offer cheap prices include American Airlines from $121 and Southwest from $167 one-way.

  • What are the most popular routes from Des Moines to Louisiana?

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $191). Flying from Des Moines to Louisiana in December is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$466FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$386FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$270Average$387FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$312Average$392FlexibilityNo cancel feeOn-time69%

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