$166+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:57 am
DSM
- MSY
1 stop4h 20m
Delta
Sat 10/310:45 am
MSY
- DSM
1 stop4h 30m
Delta
Deal found 6/8![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:35 pm
DSM
- MSY
2 stops9h 10m
United Airlines
Sat 9/265:28 pm
MSY
- DSM
1 stop4h 48m
United Airlines
Deal found 6/8![United Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:10 am
DSM
- MSY
1 stop6h 25m
Southwest
Sat 10/310:10 am
MSY
- DSM
2 stops9h 30m
Southwest
Deal found 6/8![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:45 pm
DSM
- MSY
1 stop4h 47m
Delta
Thu 10/11:00 pm
MSY
- DSM
1 stop5h 00m
Delta
Deal found 6/8![Delta logo]()
$290
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:45 pm
DSM
- MSY
1 stop4h 47m
Delta
Sat 10/35:15 am
MSY
- DSM
1 stop5h 28m
Delta
Deal found 6/8![Delta logo]()
$307
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:45 pm
DSM
- MSY
1 stop4h 47m
Delta
Thu 10/11:00 pm
MSY
- DSM
1 stop5h 00m
Delta
Deal found 6/8![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:23 am
DSM
- BTR
1 stop5h 35m
American Airlines
Sat 8/16:47 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 6/7![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:35 pm
DSM
- MSY
1 stop7h 56m
United Airlines
Fri 9/255:28 pm
MSY
- DSM
1 stop4h 47m
United Airlines
Deal found 6/8![United Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:10 am
DSM
- MSY
2 stops7h 55m
Southwest
Sat 9/268:00 am
MSY
- DSM
2 stops11h 25m
Southwest
Deal found 6/8![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
DSM
- MSY
1 stop5h 55m
Southwest
Tue 7/73:55 pm
MSY
- DSM
1 stop6h 55m
Southwest
Deal found 6/8![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:45 pm
DSM
- MSY
1 stop4h 47m
Delta
Sat 10/35:15 am
MSY
- DSM
1 stop5h 28m
Delta
Deal found 6/8![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:10 am
DSM
- MSY
1 stop6h 25m
Southwest
Tue 8/112:05 pm
MSY
- DSM
2 stops7h 50m
Southwest
Deal found 6/4![Southwest logo]()
$336
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:12 am
DSM
- BTR
1 stop5h 31m
American Airlines
Mon 8/36:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 6/7![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/81:50 pm
DSM
- MSY
1 stop8h 45m
Southwest
Mon 10/125:50 am
MSY
- DSM
1 stop7h 20m
Southwest
Deal found 6/4![Southwest logo]()
$361
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Mon 8/33:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 6/8![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:00 pm
DSM
- AEX
1 stop4h 38m
United Airlines
Wed 11/45:15 am
AEX
- DSM
2 stops7h 19m
United Airlines
Deal found 6/7![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:40 pm
DSM
- MSY
2 stops7h 20m
Southwest
Fri 9/186:35 am
MSY
- DSM
1 stop8h 35m
Southwest
Deal found 6/5![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:57 am
DSM
- MSY
1 stop4h 20m
Delta
Sat 10/35:15 am
MSY
- DSM
1 stop5h 28m
Delta
Deal found 6/7![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:48 pm
DSM
- BTR
1 stop6h 09m
American Airlines
Sun 7/56:16 pm
BTR
- DSM
1 stop5h 42m
American Airlines
Deal found 6/6![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
DSM
- BTR
1 stop4h 58m
United Airlines
Tue 9/14:10 pm
BTR
- DSM
1 stop6h 20m
United Airlines
Deal found 6/8![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:10 pm
DSM
- MSY
1 stop7h 00m
Southwest
Sun 11/85:50 am
MSY
- DSM
1 stop7h 20m
Southwest
Deal found 6/5![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
DSM
- AEX
2 stops9h 25m
United Airlines
Mon 8/104:00 pm
AEX
- DSM
1 stop6h 35m
United Airlines
Deal found 6/7![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:30 am
DSM
- MSY
1 stop4h 27m
Delta
Sun 7/195:20 am
MSY
- DSM
1 stop5h 25m
Delta
Deal found 6/8![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:25 pm
DSM
- MSY
1 stop7h 20m
Southwest
Sun 11/156:00 am
MSY
- DSM
2 stops7h 10m
Southwest
Deal found 6/4![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:54 am
DSM
- MSY
1 stop4h 31m
Delta
Sun 7/55:20 am
MSY
- DSM
1 stop5h 25m
Delta
Deal found 6/8![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:27 am
DSM
- MSY
2 stops8h 36m
United Airlines
Sat 10/33:38 pm
MSY
- DSM
2 stops8h 19m
United Airlines
Deal found 6/4![United Airlines logo]()
$433
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated June 8, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:35 am
DSM
- BTR
1 stop7h 12m
Delta
Sat 6/276:09 am
BTR
- DSM
1 stop4h 40m
Delta
Deal found 6/8![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/254:40 pm
DSM
- MSY
1 stop7h 15m
Southwest
Wed 7/15:00 am
MSY
- DSM
1 stop6h 30m
Southwest
Deal found 6/4![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:10 am
DSM
- MSY
2 stops11h 55m
Southwest
Tue 6/303:55 pm
MSY
- DSM
1 stop6h 50m
Southwest
Deal found 6/5![Southwest logo]()
$384
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:45 pm
DSM
- MSY
1 stop7h 35m
Southwest
Fri 7/35:15 pm
MSY
- DSM
1 stop6h 15m
Southwest
Deal found 6/5![Southwest logo]()
$336
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:23 am
DSM
- BTR
1 stop5h 35m
American Airlines
Sat 8/16:47 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 6/7![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:37 pm
DSM
- MSY
2 stops26h 49m
Multiple Airlines
Fri 7/1012:36 pm
MSY
- DSM
1 stop27h 33m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:05 pm
DSM
- MSY
1 stop9h 45m
Southwest
Fri 7/105:40 am
MSY
- DSM
1 stop5h 50m
Southwest
Deal found 6/5![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
DSM
- MSY
1 stop5h 55m
Southwest
Tue 7/73:55 pm
MSY
- DSM
1 stop6h 55m
Southwest
Deal found 6/8![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Mon 8/33:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 6/8![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
DSM
- BTR
1 stop5h 19m
American Airlines
Wed 8/511:14 am
BTR
- DSM
1 stop6h 38m
American Airlines
Deal found 6/7![American Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:08 pm
DSM
- MSY
2 stops47h 19m
Multiple Airlines
Thu 7/309:48 pm
MSY
- DSM
1 stop15h 46m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$366
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:20 am
DSM
- MSY
1 stop5h 55m
Southwest
Mon 8/35:15 pm
MSY
- DSM
1 stop6h 20m
Southwest
Deal found 6/8![Southwest logo]()
$389
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:25 pm
DSM
- MSY
1 stop6h 03m
Delta
Deal found 6/5![Delta logo]()
$166
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:40 pm
DSM
- MSY
2 stops9h 46m
United Airlines
Deal found 6/4![United Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm
DSM
- MSY
2 stops26h 11m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$195
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:20 am
DSM
- MSY
2 stops9h 25m
Southwest
Deal found 6/7![Southwest logo]()
$196
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
DSM
- MSY
2 stops11h 58m
United Airlines
Deal found 6/5![United Airlines logo]()
$216
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:30 am
DSM
- BTR
1 stop6h 49m
Delta
Deal found 6/8![Delta logo]()
$251
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:53 am
DSM
- BTR
2 stops9h 00m
American Airlines
Deal found 6/8![American Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm
DSM
- MSY
3 stops40h 01m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$559
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (Delta) |
One-way from | $166 (Delta) |
Popular in | May |
Cheapest in | September |
Average price | $394 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Tue 7/7
5:12 am-10:43 am
1 stop5h 31m
Baton Rouge Ryan
Mon 8/3
6:16 pm-11:58 pm
1 stop5h 42m
$334
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/8
1:50 pm-10:35 pm
1 stop8h 45m
New Orleans Louis Armstrong
Mon 10/12
5:50 am-1:10 pm
1 stop7h 20m
$361
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Tue 7/7
2:25 pm-9:56 pm
1 stop7h 31m
Baton Rouge Ryan
Mon 8/3
3:57 pm-10:37 pm
1 stop6h 40m
$364
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/15
2:40 pm-10:00 pm
2 stops7h 20m
New Orleans Louis Armstrong
Fri 9/18
6:35 am-3:10 pm
1 stop8h 35m
$374
Quickest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 9/30
10:57 am-3:17 pm
1 stop4h 20m
New Orleans Louis Armstrong
Sat 10/3
5:15 am-10:43 am
1 stop5h 28m
$381
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 10/31
2:10 pm-9:10 pm
1 stop7h 00m
New Orleans Louis Armstrong
Sun 11/8
5:50 am-1:10 pm
1 stop7h 20m
$381
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 11/12
4:25 pm-11:45 pm
1 stop7h 20m
New Orleans Louis Armstrong
Sun 11/15
6:00 am-1:10 pm
2 stops7h 10m
$386
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Sat 10/31
3:00 pm-7:38 pm
1 stop4h 38m
Alexandria
Wed 11/4
5:15 am-12:34 pm
2 stops7h 19m
$394
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Thu 7/2
4:48 pm-10:57 pm
1 stop6h 09m
Baton Rouge Ryan
Sun 7/5
6:16 pm-11:58 pm
1 stop5h 42m
$398
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Sat 8/29
6:15 am-11:13 am
1 stop4h 58m
Baton Rouge Ryan
Tue 9/1
4:10 pm-10:30 pm
1 stop6h 20m
$399
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $151). Flying from Des Moines to Louisiana in February is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 40 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated June 8, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
Complete your trip to Louisiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Louisiana by cabin class
Find flights from Des Moines to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on June 8, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$432 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$387 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |