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$97+ Cheap flights from Des Moines (DSM) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Des Moines to Louisiana

Cheapest flights from Des Moines to Louisiana
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:27 pm
DSM
-
MSY
2 stops38h 11m
Multiple Airlines
Wed 3/47:27 pm
MSY
-
DSM
1 stop27h 24m
Multiple Airlines
Deal found 1/25$210
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:39 pm
DSM
-
MSY
2 stops17h 59m
Multiple Airlines
Thu 2/262:34 pm
MSY
-
DSM
1 stop28h 30m
Multiple Airlines
Deal found 1/27$254
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:27 pm
DSM
-
MSY
1 stop23h 20m
Frontier
Fri 3/63:36 pm
MSY
-
DSM
1 stop27h 40m
Frontier
Deal found 1/26$259
This CheapOair deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:27 pm
DSM
-
MSY
1 stop19h 14m
Frontier
Mon 3/98:30 pm
MSY
-
DSM
1 stop13h 35m
Frontier
Deal found 1/25$260
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:15 pm
DSM
-
BTR
1 stop4h 46m
Delta
Tue 3/36:18 am
BTR
-
DSM
1 stop5h 01m
Delta
Deal found 1/27$269
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:26 am
DSM
-
MSY
2 stops21h 53m
Multiple Airlines
Wed 3/257:20 pm
MSY
-
DSM
1 stop18h 09m
Multiple Airlines
Deal found 1/26$271
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:32 am
DSM
-
BTR
2 stops11h 14m
American Airlines
Tue 3/34:27 pm
BTR
-
DSM
2 stops7h 13m
American Airlines
Deal found 1/27$279
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:27 pm
DSM
-
MSY
2 stops18h 04m
Multiple Airlines
Mon 3/92:40 pm
MSY
-
DSM
1 stop7h 23m
Multiple Airlines
Deal found 1/25$300
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:46 pm
DSM
-
MSY
1 stop13h 14m
Multiple Airlines
Thu 5/146:15 am
MSY
-
DSM
1 stop9h 00m
Multiple Airlines
Deal found 1/27$301
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:20 pm
DSM
-
MSY
1 stop23h 11m
Multiple Airlines
Mon 3/27:27 pm
MSY
-
DSM
2 stops39h 08m
Multiple Airlines
Deal found 1/26$308
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:57 pm
DSM
-
MSY
1 stop17h 18m
Multiple Airlines
Wed 5/278:05 am
MSY
-
DSM
1 stop24h 48m
Multiple Airlines
Deal found 1/27$316
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:51 pm
DSM
-
BTR
1 stop5h 05m
American Airlines
Sat 2/144:27 pm
BTR
-
DSM
2 stops7h 13m
American Airlines
Deal found 1/26$355

Find flight deals from Des Moines to Louisiana

Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$210
(Kiwi.com)

One-way from

$97
(Kiwi.com)

Popular in

February

Cheapest in

November

Average price

$397
Provider with most accurate pricing for Des Moines-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-New Orleans Louis Armstrong flights.
Search Deals
From Des Moines to Louisiana
Search Deals
One-way flight from Des Moines to Louisiana
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Des Moines

Fly to

Louisiana

Route

Depart

Return

Price

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Thu 2/26

7:27 pm-6:47 pm

1 stop23h 20m

New Orleans Louis Armstrong

Wed 3/4

7:27 pm-10:51 pm

1 stop27h 24m

$236

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 2/23

3:39 pm-9:38 am

2 stops17h 59m

New Orleans Louis Armstrong

Thu 2/26

2:34 pm-7:04 pm

1 stop28h 30m

$254

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 2/24

7:15 am-12:51 pm

1 stop5h 36m

Baton Rouge Ryan

Tue 3/3

1:30 pm-9:19 pm

1 stop7h 49m

$269

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 2/24

10:57 am-10:01 pm

2 stops11h 04m

Baton Rouge Ryan

Tue 3/3

6:18 am-11:19 am

1 stop5h 01m

$274

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 2/23

7:20 pm-6:31 pm

1 stop23h 11m

New Orleans Louis Armstrong

Mon 3/2

7:27 pm-10:35 am

2 stops39h 08m

$308

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Tue 2/24

8:35 am-2:20 pm

1 stop5h 45m

New Orleans Louis Armstrong

Tue 3/3

7:45 am-11:25 am

1 stop3h 40m

$317

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sat 2/28

6:10 am-12:00 pm

1 stop5h 50m

New Orleans Louis Armstrong

Tue 3/3

5:10 pm-9:10 pm

1 stop4h 00m

$317

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 3/4

12:04 pm-4:30 pm

1 stop4h 26m

New Orleans Louis Armstrong

Sat 3/7

5:25 am-12:14 pm

1 stop6h 49m

$329

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Thu 2/26

6:15 pm-12:10 am

2 stops5h 55m

New Orleans Louis Armstrong

Wed 3/4

1:00 pm-9:10 pm

2 stops8h 10m

$340

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 2/23

3:24 pm-10:37 pm

1 stop7h 13m

New Orleans Louis Armstrong

Thu 2/26

2:32 pm-8:07 pm

1 stop5h 35m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 25 results
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Best time to book a flight from Des Moines to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisiana

What is the cheapest month to book a flight from Des Moines to Louisiana?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in December is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,124 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,212 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,201 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Louisiana?

    For a flight from Des Moines to Louisiana, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Louisiana?

    Departing from Des Moines to Louisiana will take you 5h 36m. The distance between Des Moines and Louisiana is about 773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Des Moines to Louisiana?

    Most travelers choose Des Moines - New Orleans Louis Armstrong, Des Moines - Baton Rouge Ryan or Des Moines - Alexandria when deciding on the best route from Des Moines to Louisiana.

  • Can I find deals for flights from Des Moines to Louisiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisiana.

  • Can I find deals for business class flights from Des Moines to Louisiana?

    Yes. Cheapflights offers flight deals from Des Moines to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisiana?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $193). Flying from Des Moines to Louisiana in December is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
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Des Moines to Reagan-National flights
Des Moines to Charlotte flights

Top 4 airlines flying from Des Moines to Louisiana

Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$426FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$396FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$270Average$386FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$312Average$401FlexibilityNo cancel feeOn-time69%

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