$163+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:09 pm -
1 stop28h 20m
Fri 10/910:37 am -
1 stop8h 53m
Deal found 8/18![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:02 pm -
1 stop15h 58m
Wed 10/75:17 pm -
2 stops21h 25m
Deal found 8/20![Multiple Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:14 pm -
1 stop6h 44m
Sat 9/2611:16 am -
1 stop6h 36m
Deal found 8/16![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:40 pm -
2 stops7h 50m
Sat 9/266:50 am -
1 stop9h 20m
Deal found 8/19![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
2 stops9h 20m
Wed 12/23:05 pm -
2 stops6h 55m
Deal found 8/17![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:10 pm -
1 stop5h 00m
Thu 10/85:50 pm -
1 stop5h 05m
Deal found 8/17![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:02 pm -
1 stop6h 26m
Wed 9/94:10 pm -
1 stop6h 20m
Deal found 8/21![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:11 pm -
1 stop4h 35m
Wed 9/91:32 pm -
2 stops7h 14m
Deal found 8/21![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:59 am -
1 stop4h 32m
Sat 9/55:12 am -
1 stop5h 31m
Deal found 8/17![Delta logo]()
$358
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:58 pm -
1 stop7h 29m
Mon 11/164:29 pm -
1 stop4h 44m
Deal found 8/18![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am -
2 stops9h 15m
Tue 10/137:00 am -
2 stops7h 20m
Deal found 8/17![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:22 pm -
1 stop4h 33m
Mon 8/246:14 pm -
1 stop5h 11m
Deal found 8/19![American Airlines logo]()
$439
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:10 am -
2 stops6h 45m
Thu 10/12:25 pm -
2 stops8h 45m
Deal found 8/18![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:11 pm -
1 stop4h 35m
Wed 9/91:32 pm -
2 stops7h 14m
Deal found 8/21![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop5h 18m
Sat 10/105:20 am -
2 stops8h 55m
Deal found 8/18![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:28 am -
1 stop6h 22m
Sun 11/86:15 pm -
1 stop5h 42m
Deal found 8/19![American Airlines logo]()
$679
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:59 am -
1 stop4h 32m
Sat 9/55:12 am -
1 stop5h 31m
Deal found 8/16![Delta logo]()
$358
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:10 pm -
1 stop5h 00m
Mon 11/25:50 am -
1 stop7h 20m
Deal found 8/19![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/268:00 am -
1 stop5h 22m
Sat 1/304:04 pm -
1 stop6h 26m
Deal found 8/20![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:58 pm -
1 stop7h 29m
Mon 11/164:29 pm -
1 stop4h 44m
Deal found 8/17![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:25 pm -
1 stop7h 20m
Mon 12/143:05 pm -
2 stops6h 55m
Deal found 8/16![Southwest logo]()
$376
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/218:00 am -
1 stop5h 15m
Mon 1/255:25 pm -
1 stop5h 05m
Deal found 8/16![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:10 pm -
1 stop11h 25m
Mon 11/95:40 am -
1 stop10h 10m
Deal found 8/20![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1310:55 am -
1 stop4h 31m
Tue 2/165:30 am -
1 stop4h 48m
Deal found 8/21![Delta logo]()
$422
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:33 am -
2 stops10h 24m
Sat 9/59:53 am -
1 stop4h 21m
Deal found 8/16![United Airlines logo]()
$443
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:10 am -
2 stops12h 00m
Sun 10/116:40 am -
2 stops6h 55m
Deal found 8/18![Southwest logo]()
$463
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop14h 00m
Tue 10/279:30 am -
1 stop13h 00m
Deal found 8/20![United Airlines logo]()
$546
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:03 pm -
1 stop6h 53m
Mon 10/125:53 pm -
1 stop4h 40m
Deal found 8/19![Delta logo]()
$561
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:24 pm -
2 stops7h 52m
Mon 10/124:07 pm -
1 stop6h 08m
Deal found 8/19![United Airlines logo]()
$753
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
3 stops26h 43m
Tue 9/82:05 pm -
2 stops9h 28m
Deal found 8/20![United Airlines logo]()
$780
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
2 stops20h 53m
Sun 11/85:00 am -
2 stops17h 50m
Deal found 8/16![United Airlines logo]()
$859
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated August 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:22 pm -
1 stop4h 33m
Mon 8/246:14 pm -
1 stop5h 11m
Deal found 8/19![American Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am -
2 stops9h 30m
Mon 8/247:15 am -
1 stop6h 59m
Deal found 8/19![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:15 am -
1 stop4h 58m
Fri 8/286:14 pm -
1 stop20h 00m
Deal found 8/17![United Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:59 am -
1 stop4h 32m
Sat 9/55:12 am -
1 stop5h 31m
Deal found 8/17![Delta logo]()
$358
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:02 pm -
1 stop6h 26m
Wed 9/94:10 pm -
1 stop6h 20m
Deal found 8/21![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:11 pm -
1 stop4h 35m
Wed 9/91:32 pm -
2 stops7h 14m
Deal found 8/21![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:15 am -
1 stop6h 58m
Sun 9/134:00 pm -
1 stop7h 33m
Deal found 8/16![United Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Sun 9/135:26 pm -
2 stops26h 07m
Deal found 8/16![Frontier logo]()
$410
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:14 pm -
1 stop6h 44m
Sat 9/2611:16 am -
1 stop6h 36m
Deal found 8/16![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:40 pm -
2 stops7h 50m
Sat 9/266:50 am -
1 stop9h 20m
Deal found 8/19![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:50 pm -
2 stops6h 55m
Fri 9/253:00 pm -
2 stops7h 15m
Deal found 8/17![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:57 pm -
1 stop5h 41m
Sun 10/46:05 am -
1 stop7h 54m
Deal found 8/21![American Airlines logo]()
$391
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:02 pm -
1 stop6h 35m
Deal found 8/20![United Airlines logo]()
$163
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:10 pm -
1 stop5h 00m
Deal found 8/17![Southwest logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:43 am -
2 stops31h 27m
Deal found 8/18![Multiple Airlines logo]()
$216
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:35 am -
1 stop5h 41m
Deal found 8/18![Delta logo]()
$268
This deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:02 pm -
1 stop4h 58m
Deal found 8/18![United Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
2 stops9h 30m
Deal found 8/18![United Airlines logo]()
$342
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (Kiwi.com) |
One-way from | $163 (United Airlines) |
Popular in | July |
Cheapest in | September |
Average price | $387 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Tue 9/29
6:10 am-12:55 pm
2 stops6h 45m
New Orleans Louis Armstrong
Thu 10/1
2:25 pm-11:10 pm
2 stops8h 45m
$335
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Sat 9/5
4:11 pm-8:46 pm
1 stop4h 35m
Baton Rouge Ryan
Wed 9/9
1:32 pm-8:46 pm
2 stops7h 14m
$354
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Wed 9/2
10:59 am-3:31 pm
1 stop4h 32m
New Orleans Louis Armstrong
Sat 9/5
5:12 am-10:43 am
1 stop5h 31m
$358
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Sun 10/4
6:00 am-11:18 am
1 stop5h 18m
Baton Rouge Ryan
Sat 10/10
5:20 am-2:15 pm
2 stops8h 55m
$359
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 10/30
7:10 pm-12:10 am
1 stop5h 00m
New Orleans Louis Armstrong
Mon 11/2
5:50 am-1:10 pm
1 stop7h 20m
$365
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 11/13
2:58 pm-10:27 pm
1 stop7h 29m
New Orleans Louis Armstrong
Mon 11/16
4:29 pm-9:13 pm
1 stop4h 44m
$365
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sun 12/13
4:25 pm-11:45 pm
1 stop7h 20m
New Orleans Louis Armstrong
Mon 12/14
3:05 pm-10:00 pm
2 stops6h 55m
$376
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Fri 11/6
12:10 pm-11:35 pm
1 stop11h 25m
New Orleans Louis Armstrong
Mon 11/9
5:40 am-3:50 pm
1 stop10h 10m
$390
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Tue 1/26
8:00 am-1:22 pm
1 stop5h 22m
Baton Rouge Ryan
Sat 1/30
4:04 pm-10:30 pm
1 stop6h 26m
$399
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 1/21
8:00 am-1:15 pm
1 stop5h 15m
New Orleans Louis Armstrong
Mon 1/25
5:25 pm-10:30 pm
1 stop5h 05m
$405
Showing 1-10 of 25 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-AEX
DSM-BTR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-AEX
DSM-BTR
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $367). Flying from Des Moines to Louisiana in July is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is below average for this route at the moment.
Des Moines to Louisiana flights typically cost between $329 and $507 in October.The cheapest round-trip price found within the last 5 days was $281 on Multiple Airlines (Oct 2-Oct 9).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated August 21, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
Complete your trip to Louisiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Louisiana by cabin class
Find flights from Des Moines to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on August 21, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$283 | Average$433 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$290 | Average$420 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$312 | Average$396 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |