$151+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:44 pm
DSM
- MSY
1 stop27h 35m
Multiple Airlines
Mon 6/225:21 pm
MSY
- DSM
2 stops44h 10m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:30 am
DSM
- MSY
1 stop5h 05m
American Airlines
Wed 6/175:19 pm
MSY
- DSM
1 stop7h 16m
American Airlines
Deal found 4/28![American Airlines logo]()
$291
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:24 pm
DSM
- MSY
2 stops8h 06m
United Airlines
Tue 9/155:35 pm
MSY
- DSM
1 stop4h 51m
United Airlines
Deal found 4/27![United Airlines logo]()
$296
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Sun 6/79:55 pm
MSY
- DSM
1 stop15h 36m
Frontier
Deal found 4/27![Frontier logo]()
$301
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:58 pm
DSM
- MSY
1 stop4h 44m
United Airlines
Sat 5/233:48 pm
MSY
- DSM
1 stop6h 47m
United Airlines
Deal found 4/28![United Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:16 pm
DSM
- MSY
1 stop6h 54m
Multiple Airlines
Mon 6/158:28 pm
MSY
- DSM
2 stops41h 03m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:20 am
DSM
- BTR
1 stop5h 00m
United Airlines
Mon 8/34:09 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 4/28![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
DSM
- MSY
2 stops8h 49m
American Airlines
Sat 5/236:47 am
MSY
- DSM
1 stop6h 31m
American Airlines
Deal found 4/28![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/264:57 pm
DSM
- MSY
2 stops21h 51m
Multiple Airlines
Wed 7/295:25 pm
MSY
- DSM
1 stop15h 08m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:20 am
DSM
- MSY
1 stop4h 41m
United Airlines
Thu 6/48:04 am
MSY
- DSM
1 stop8h 11m
United Airlines
Deal found 4/30![United Airlines logo]()
$321
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:16 pm
DSM
- MSY
1 stop6h 47m
Frontier
Thu 6/259:48 pm
MSY
- DSM
1 stop15h 43m
Frontier
Deal found 4/28![Frontier logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:23 am
DSM
- BTR
1 stop5h 35m
American Airlines
Sat 8/16:47 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 4/26![American Airlines logo]()
$329
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:24 pm
DSM
- MSY
2 stops8h 06m
United Airlines
Tue 9/155:35 pm
MSY
- DSM
1 stop4h 51m
United Airlines
Deal found 4/27![United Airlines logo]()
$296
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:23 am
DSM
- BTR
1 stop5h 35m
American Airlines
Sat 8/16:47 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 4/26![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:15 pm
DSM
- MSY
1 stop6h 24m
Delta
Sat 9/511:18 am
MSY
- DSM
1 stop5h 31m
Delta
Deal found 4/26![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am
DSM
- MSY
2 stops10h 10m
Southwest
Wed 9/306:00 am
MSY
- DSM
1 stop7h 55m
Southwest
Deal found 4/26![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:20 am
DSM
- BTR
1 stop5h 00m
United Airlines
Mon 8/34:09 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 4/28![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:35 am
DSM
- BTR
1 stop7h 12m
Delta
Mon 6/224:00 pm
BTR
- DSM
1 stop6h 31m
Delta
Deal found 4/30![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:10 am
DSM
- MSY
2 stops7h 55m
Southwest
Sat 8/226:50 am
MSY
- DSM
1 stop9h 20m
Southwest
Deal found 4/30![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:23 am
DSM
- MSY
1 stop5h 15m
United Airlines
Thu 9/108:04 am
MSY
- DSM
1 stop8h 09m
United Airlines
Deal found 4/27![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:10 am
DSM
- MSY
2 stops7h 55m
Southwest
Fri 9/182:00 pm
MSY
- DSM
2 stops8h 10m
Southwest
Deal found 4/30![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:00 pm
DSM
- BTR
1 stop6h 24m
American Airlines
Tue 5/194:53 pm
BTR
- DSM
1 stop6h 23m
American Airlines
Deal found 4/30![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:35 am
DSM
- BTR
1 stop7h 12m
Delta
Mon 8/310:25 am
BTR
- DSM
1 stop7h 28m
Delta
Deal found 4/27![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- MSY
2 stops7h 45m
Southwest
Tue 9/152:05 pm
MSY
- DSM
2 stops7h 50m
Southwest
Deal found 4/27![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
DSM
- MSY
1 stop6h 56m
United Airlines
Wed 8/197:00 am
MSY
- DSM
2 stops9h 13m
United Airlines
Deal found 4/30![United Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:25 pm
DSM
- BTR
1 stop7h 31m
Delta
Sun 7/124:00 pm
BTR
- DSM
1 stop6h 29m
Delta
Deal found 4/26![Delta logo]()
$388
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
DSM
- AEX
2 stops8h 50m
United Airlines
Sat 5/304:00 pm
AEX
- DSM
1 stop6h 35m
United Airlines
Deal found 4/27![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:18 pm
DSM
- AEX
2 stops8h 19m
American Airlines
Sat 5/166:26 pm
AEX
- DSM
1 stop5h 33m
American Airlines
Deal found 4/27![American Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:10 am
DSM
- MSY
2 stops7h 55m
Southwest
Thu 9/102:00 pm
MSY
- DSM
2 stops8h 10m
Southwest
Deal found 4/27![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:24 pm
DSM
- MSY
2 stops8h 06m
United Airlines
Thu 9/177:00 am
MSY
- DSM
1 stop5h 19m
United Airlines
Deal found 4/27![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 am
DSM
- BTR
2 stops12h 45m
American Airlines
Sat 7/186:47 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 4/26![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:23 am
DSM
- MSY
1 stop5h 26m
United Airlines
Thu 7/163:43 pm
MSY
- DSM
1 stop6h 52m
United Airlines
Deal found 4/26![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:25 pm
DSM
- AEX
1 stop7h 15m
Delta
Fri 6/195:09 pm
AEX
- DSM
1 stop5h 22m
Delta
Deal found 4/28![Delta logo]()
$532
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:26 am
DSM
- AEX
2 stops10h 49m
Delta
Sat 5/1612:10 pm
AEX
- DSM
2 stops9h 02m
Delta
Deal found 4/27![Delta logo]()
$557
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 am
DSM
- BTR
2 stops8h 29m
United Airlines
Sat 8/12:05 pm
BTR
- DSM
2 stops9h 39m
United Airlines
Deal found 4/26![United Airlines logo]()
$622
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated May 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:00 pm
DSM
- BTR
1 stop6h 24m
American Airlines
Mon 5/114:53 pm
BTR
- DSM
1 stop7h 06m
American Airlines
Deal found 4/28![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:15 am
DSM
- BTR
2 stops9h 16m
United Airlines
Tue 5/124:06 pm
BTR
- DSM
1 stop6h 39m
United Airlines
Deal found 4/29![United Airlines logo]()
$404
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- MSY
1 stop6h 54m
Frontier
Thu 5/149:55 pm
MSY
- DSM
1 stop15h 36m
Frontier
Deal found 4/27![Frontier logo]()
$351
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:00 pm
DSM
- BTR
1 stop6h 24m
American Airlines
Tue 5/194:53 pm
BTR
- DSM
1 stop6h 23m
American Airlines
Deal found 4/30![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
DSM
- MSY
1 stop5h 09m
American Airlines
Sat 5/236:00 pm
MSY
- DSM
1 stop5h 57m
American Airlines
Deal found 4/29![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:58 pm
DSM
- MSY
1 stop4h 44m
United Airlines
Sat 5/233:48 pm
MSY
- DSM
1 stop6h 47m
United Airlines
Deal found 4/28![United Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
DSM
- MSY
2 stops8h 49m
American Airlines
Sat 5/236:47 am
MSY
- DSM
1 stop6h 31m
American Airlines
Deal found 4/28![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:59 pm
DSM
- MSY
2 stops18h 34m
Multiple Airlines
Mon 5/255:29 pm
MSY
- DSM
1 stop22h 06m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:01 pm
DSM
- AEX
1 stop4h 54m
United Airlines
Sat 5/304:00 pm
AEX
- DSM
1 stop6h 35m
United Airlines
Deal found 4/27![United Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:20 am
DSM
- MSY
1 stop4h 41m
United Airlines
Thu 6/48:04 am
MSY
- DSM
1 stop8h 11m
United Airlines
Deal found 4/30![United Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:41 pm
DSM
- MSY
2 stops22h 49m
Multiple Airlines
Thu 6/49:55 pm
MSY
- DSM
1 stop15h 36m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:33 pm
DSM
- MSY
1 stop5h 40m
Delta
Sun 5/316:17 am
MSY
- DSM
1 stop4h 51m
Delta
Deal found 4/29![Delta logo]()
$364
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:57 pm
DSM
- MSY
2 stops48h 00m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$151
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:20 am
DSM
- MSY
1 stop4h 41m
United Airlines
Deal found 4/30![United Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:40 pm
DSM
- MSY
1 stop28h 17m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:48 pm
DSM
- MSY
2 stops44h 44m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:37 pm
DSM
- MSY
2 stops30h 12m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$187
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:25 am
DSM
- MSY
1 stop5h 24m
Delta
Deal found 4/29![Delta logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:38 pm
DSM
- MSY
1 stop9h 22m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 am
DSM
- MSY
2 stops8h 14m
United Airlines
Deal found 4/27![United Airlines logo]()
$196
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1410:54 am
DSM
- MSY
1 stop4h 31m
Delta
Deal found 4/30![Delta logo]()
$204
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:40 pm
DSM
- MSY
2 stops8h 12m
United Airlines
Deal found 4/30![United Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:59 am
DSM
- MSY
2 stops24h 08m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$216
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:20 am
DSM
- BTR
1 stop7h 09m
United Airlines
Deal found 4/27![United Airlines logo]()
$251
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $280 (Kiwi.com) |
One-way from | $151 (Kiwi.com) |
Popular in | May |
Cheapest in | September |
Average price | $464 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/8
3:24 pm-11:30 pm
2 stops8h 06m
New Orleans Louis Armstrong
Tue 9/15
5:35 pm-10:26 pm
1 stop4h 51m
$296
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Tue 7/7
6:20 am-11:20 am
1 stop5h 00m
Baton Rouge Ryan
Mon 8/3
4:09 pm-10:35 pm
1 stop6h 26m
$309
Quickest round-trip
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Fri 7/3
5:23 am-10:58 am
1 stop5h 35m
Baton Rouge Ryan
Sat 8/1
6:47 pm-11:58 pm
1 stop5h 11m
$329
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 9/2
2:15 pm-8:39 pm
1 stop6h 24m
New Orleans Louis Armstrong
Sat 9/5
11:18 am-4:49 pm
1 stop5h 31m
$349
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/8
11:23 am-4:38 pm
1 stop5h 15m
New Orleans Louis Armstrong
Thu 9/10
8:04 am-4:13 pm
1 stop8h 09m
$349
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 9/26
5:30 am-3:40 pm
2 stops10h 10m
New Orleans Louis Armstrong
Wed 9/30
6:00 am-1:55 pm
1 stop7h 55m
$354
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Mon 6/15
5:35 am-12:47 pm
1 stop7h 12m
Baton Rouge Ryan
Mon 6/22
4:00 pm-10:31 pm
1 stop6h 31m
$354
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 8/19
6:10 am-2:05 pm
2 stops7h 55m
New Orleans Louis Armstrong
Sat 8/22
6:50 am-4:10 pm
1 stop9h 20m
$354
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/15
6:10 am-2:05 pm
2 stops7h 55m
New Orleans Louis Armstrong
Fri 9/18
2:00 pm-10:10 pm
2 stops8h 10m
$359
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/8
2:40 pm-10:25 pm
2 stops7h 45m
New Orleans Louis Armstrong
Tue 9/15
2:05 pm-9:55 pm
2 stops7h 50m
$369
Showing 1-10 of 34 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $151). Flying from Des Moines to Louisiana in May is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated May 1, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on May 1, 2026.
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$415 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$426 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |