$124+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Sep 2 — Sep 91
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
This Expedia deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm
DSM
- MSY
1 stop6h 48m
Frontier
Mon 9/1410:48 am
MSY
- DSM
1 stop8h 45m
Frontier
Deal found 7/30![Frontier logo]()
$226
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Thu 8/209:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 7/29![Frontier logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:09 pm
DSM
- MSY
1 stop28h 20m
Multiple Airlines
Mon 10/510:48 am
MSY
- DSM
1 stop8h 45m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:10 pm
DSM
- BTR
1 stop4h 39m
Delta
Sat 9/196:07 am
BTR
- DSM
1 stop4h 39m
Delta
Deal found 8/3![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:02 pm
DSM
- BTR
1 stop6h 26m
United Airlines
Sat 9/192:15 pm
BTR
- DSM
2 stops9h 18m
United Airlines
Deal found 7/30![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:55 am
DSM
- MSY
1 stop5h 19m
American Airlines
Sat 9/56:00 pm
MSY
- DSM
1 stop5h 16m
American Airlines
Deal found 7/30![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:25 pm
DSM
- MSY
2 stops7h 35m
Southwest
Thu 9/36:35 am
MSY
- DSM
1 stop7h 10m
Southwest
Deal found 7/30![Southwest logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:38 pm
DSM
- MSY
1 stop9h 22m
Multiple Airlines
Fri 9/47:11 pm
MSY
- DSM
2 stops48h 46m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:13 pm
DSM
- BTR
1 stop5h 17m
American Airlines
Thu 9/36:13 pm
BTR
- DSM
1 stop5h 17m
American Airlines
Deal found 7/30![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:22 pm
DSM
- BTR
1 stop4h 31m
American Airlines
Sat 9/196:42 pm
BTR
- DSM
1 stop4h 30m
American Airlines
Deal found 7/29![American Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:28 am
DSM
- MSY
2 stops32h 04m
Multiple Airlines
Sun 9/69:23 pm
MSY
- DSM
1 stop16h 11m
Multiple Airlines
Deal found 8/2![Multiple Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:28 am
DSM
- AEX
1 stop4h 57m
Delta
Sat 8/225:07 pm
AEX
- DSM
1 stop5h 30m
Delta
Deal found 8/3![Delta logo]()
$338
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:22 pm
DSM
- BTR
1 stop4h 31m
American Airlines
Sat 9/196:42 pm
BTR
- DSM
1 stop4h 30m
American Airlines
Deal found 7/29![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:10 pm
DSM
- BTR
1 stop4h 39m
Delta
Sat 9/191:32 pm
BTR
- DSM
2 stops7h 14m
Delta
Deal found 7/29![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:40 pm
DSM
- MSY
2 stops7h 50m
Southwest
Fri 9/113:00 pm
MSY
- DSM
2 stops7h 15m
Southwest
Deal found 8/2![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:00 pm
DSM
- BTR
1 stop5h 01m
United Airlines
Sat 1/94:04 pm
BTR
- DSM
1 stop6h 26m
United Airlines
Deal found 8/2![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:23 am
DSM
- AEX
2 stops11h 18m
Delta
Sat 8/2211:44 am
AEX
- DSM
2 stops8h 55m
Delta
Deal found 8/3![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:50 pm
DSM
- MSY
1 stop6h 05m
Southwest
Wed 9/306:00 am
MSY
- DSM
1 stop7h 55m
Southwest
Deal found 7/30![Southwest logo]()
$358
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:51 am
DSM
- MSY
1 stop5h 04m
American Airlines
Sun 9/138:00 am
MSY
- DSM
1 stop6h 16m
American Airlines
Deal found 8/2![American Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:05 pm
DSM
- MSY
1 stop10h 35m
Southwest
Mon 12/75:40 am
MSY
- DSM
2 stops8h 35m
Southwest
Deal found 7/31![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:00 am
DSM
- MSY
2 stops8h 13m
United Airlines
Mon 8/317:00 am
MSY
- DSM
1 stop5h 20m
United Airlines
Deal found 7/30![United Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
DSM
- BTR
2 stops9h 08m
Delta
Thu 9/33:57 pm
BTR
- DSM
1 stop6h 40m
Delta
Deal found 7/30![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:26 pm
DSM
- MSY
2 stops9h 33m
United Airlines
Wed 10/217:00 am
MSY
- DSM
1 stop7h 15m
United Airlines
Deal found 7/29![United Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:40 pm
DSM
- MSY
2 stops7h 50m
Southwest
Tue 9/221:55 pm
MSY
- DSM
2 stops8h 05m
Southwest
Deal found 8/1![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:54 pm
DSM
- MSY
1 stop5h 39m
Delta
Fri 9/44:28 pm
MSY
- DSM
1 stop4h 31m
Delta
Deal found 7/31![Delta logo]()
$404
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:10 pm
DSM
- MSY
1 stop5h 00m
Southwest
Fri 11/612:50 pm
MSY
- DSM
2 stops9h 10m
Southwest
Deal found 8/3![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/94:15 pm
DSM
- MSY
1 stop5h 30m
Southwest
Sun 1/176:00 am
MSY
- DSM
1 stop7h 55m
Southwest
Deal found 7/31![Southwest logo]()
$391
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:00 pm
DSM
- AEX
1 stop4h 38m
United Airlines
Tue 1/126:55 pm
AEX
- DSM
1 stop27h 35m
United Airlines
Deal found 8/2![United Airlines logo]()
$502
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:30 am
DSM
- MSY
2 stops8h 50m
Southwest
Sun 9/134:15 pm
MSY
- DSM
2 stops6h 40m
Southwest
Deal found 8/2![Southwest logo]()
$411
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:01 pm
DSM
- AEX
1 stop5h 06m
United Airlines
Sat 10/319:30 am
AEX
- DSM
1 stop4h 50m
United Airlines
Deal found 7/31![United Airlines logo]()
$502
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated August 3, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated August 3, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Thu 8/139:48 pm
MSY
- DSM
1 stop15h 46m
Frontier
Deal found 7/30![Frontier logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:44 pm
DSM
- MSY
1 stop31h 16m
Multiple Airlines
Thu 8/205:41 pm
MSY
- DSM
2 stops19h 53m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$384
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:19 pm
DSM
- MSY
1 stop6h 44m
Frontier
Thu 8/209:36 pm
MSY
- DSM
1 stop15h 58m
Frontier
Deal found 7/29![Frontier logo]()
$283
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:28 am
DSM
- AEX
1 stop4h 57m
Delta
Sat 8/225:07 pm
AEX
- DSM
1 stop5h 30m
Delta
Deal found 8/3![Delta logo]()
$338
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/264:13 pm
DSM
- MSY
1 stop5h 33m
American Airlines
Mon 8/317:08 am
MSY
- DSM
1 stop6h 17m
American Airlines
Deal found 8/2![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:10 am
DSM
- MSY
2 stops6h 45m
Southwest
Mon 8/312:00 pm
MSY
- DSM
2 stops8h 10m
Southwest
Deal found 8/2![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:50 pm
DSM
- MSY
1 stop6h 00m
Southwest
Thu 9/35:00 am
MSY
- DSM
1 stop6h 25m
Southwest
Deal found 7/30![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:13 pm
DSM
- BTR
1 stop5h 17m
American Airlines
Thu 9/36:13 pm
BTR
- DSM
1 stop5h 17m
American Airlines
Deal found 7/30![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:38 pm
DSM
- MSY
1 stop9h 22m
Multiple Airlines
Fri 9/47:11 pm
MSY
- DSM
2 stops48h 46m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:22 pm
DSM
- BTR
1 stop4h 33m
American Airlines
Fri 9/46:14 pm
BTR
- DSM
1 stop5h 11m
American Airlines
Deal found 7/31![American Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:28 am
DSM
- MSY
2 stops32h 04m
Multiple Airlines
Sun 9/69:23 pm
MSY
- DSM
1 stop16h 11m
Multiple Airlines
Deal found 8/2![Multiple Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:28 pm
DSM
- MSY
1 stop6h 31m
American Airlines
Sun 9/611:16 am
MSY
- DSM
1 stop7h 39m
American Airlines
Deal found 8/2![American Airlines logo]()
$381
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am
DSM
- MSY
1 stop22h 24m
Frontier
Deal found 7/30![Frontier logo]()
$124
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:29 am
DSM
- MSY
1 stop22h 24m
Frontier
Deal found 7/30![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:58 pm
DSM
- MSY
2 stops50h 24m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$149
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:59 am
DSM
- MSY
1 stop4h 32m
Delta
Deal found 7/30![Delta logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am
DSM
- MSY
2 stops36h 27m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$167
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:21 pm
DSM
- MSY
2 stops9h 24m
United Airlines
Deal found 7/30![United Airlines logo]()
$168
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/91:05 pm
DSM
- MSY
1 stop5h 00m
Southwest
Deal found 7/31![Southwest logo]()
$183
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:45 am
DSM
- BTR
1 stop7h 07m
Delta
Deal found 7/29![Delta logo]()
$193
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:34 pm
DSM
- MSY
1 stop5h 34m
Delta
Deal found 7/30![Delta logo]()
$196
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:25 pm
DSM
- MSY
2 stops7h 40m
Southwest
Deal found 7/30![Southwest logo]()
$201
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:34 pm
DSM
- BTR
1 stop7h 19m
Delta
Deal found 7/30![Delta logo]()
$213
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:20 am
DSM
- BTR
1 stop7h 09m
United Airlines
Deal found 7/30![United Airlines logo]()
$403
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated August 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $226 (Expedia) |
One-way from | $124 (CheapOair) |
Popular in | July |
Cheapest in | September |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Sat 9/12
6:22 pm-10:53 pm
1 stop4h 31m
Baton Rouge Ryan
Sat 9/19
6:42 pm-11:12 pm
1 stop4h 30m
$335
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Sat 9/12
4:10 pm-8:49 pm
1 stop4h 39m
Baton Rouge Ryan
Sat 9/19
1:32 pm-8:46 pm
2 stops7h 14m
$344
Des MoinesAlexandria
DSM - AEX
DSMAEX
Des Moines
Tue 8/18
10:23 am-9:41 pm
2 stops11h 18m
Alexandria
Sat 8/22
11:44 am-8:39 pm
2 stops8h 55m
$349
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Wed 9/9
2:40 pm-10:30 pm
2 stops7h 50m
New Orleans Louis Armstrong
Fri 9/11
3:00 pm-10:15 pm
2 stops7h 15m
$355
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Fri 9/25
3:50 pm-9:55 pm
1 stop6h 05m
New Orleans Louis Armstrong
Wed 9/30
6:00 am-1:55 pm
1 stop7h 55m
$358
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 12/1
12:05 pm-10:40 pm
1 stop10h 35m
New Orleans Louis Armstrong
Mon 12/7
5:40 am-2:15 pm
2 stops8h 35m
$370
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Tue 9/15
2:40 pm-10:30 pm
2 stops7h 50m
New Orleans Louis Armstrong
Tue 9/22
1:55 pm-10:00 pm
2 stops8h 05m
$375
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Thu 10/29
7:10 pm-12:10 am
1 stop5h 00m
New Orleans Louis Armstrong
Fri 11/6
12:50 pm-10:00 pm
2 stops9h 10m
$383
Des MoinesBaton Rouge
DSM - BTR
DSMBTR
Des Moines
Thu 8/27
6:00 am-3:08 pm
2 stops9h 08m
Baton Rouge Ryan
Thu 9/3
3:57 pm-10:37 pm
1 stop6h 40m
$389
Des MoinesNew Orleans
DSM - MSY
DSMMSY
Des Moines
Sat 9/12
9:51 am-2:55 pm
1 stop5h 04m
New Orleans Louis Armstrong
Sun 9/13
8:00 am-2:16 pm
1 stop6h 16m
$391
Showing 1-10 of 27 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-MSY
DSM-BTR
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-MSY
DSM-BTR
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $356). Flying from Des Moines to Louisiana in July is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is below average for this route at the moment.
Des Moines to Louisiana flights typically cost between $328 and $694 in September.The cheapest round-trip price found within the last 5 days was $226 on Frontier (Sep 7-Sep 14).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated August 3, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
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Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on August 3, 2026.
Popular flight searches
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Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$433 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$277 | Average$402 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$290 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |