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$211+ Cheap flights from Des Moines to Lexington (DSM - LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LEX
août 4 — août 111
lun. 8/4
lun. 8/11
1 adult, Economy
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Cheap flight deals from Des Moines to Lexington

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated juillet 30, 2025.

Round-trip from

$249
(Delta)

One-way from

$211
(Delta)

Popular in

January

Cheapest in

April

Average price

$404
From Des Moines to Lexington Blue Grass
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One-way flight from Des Moines to Lexington Blue Grass
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Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Lexington

Cheapest flights from Des Moines to Lexington
Explore the most affordable flight options available from Des Moines to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juillet 30, 2025.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/2510:47 amDSM - LEX
1 stop6h 20mDelta
lun. 9/17:10 amLEX - DSM
1 stop7h 17mDelta
Deal found 7/28$249
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/253:21 pmDSM - LEX
2 stops6h 39mAmerican Airlines
lun. 9/16:00 amLEX - DSM
1 stop3h 37mAmerican Airlines
Deal found 7/28$254
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/31:05 pmDSM - LEX
1 stop6h 49mUnited Airlines
mer. 11/57:05 amLEX - DSM
1 stop6h 09mUnited Airlines
Deal found 7/28$379
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/303:49 pmDSM - LEX
1 stop16h 21mAllegiant Air
jeu. 7/318:56 pmLEX - DSM
1 stop12h 53mAllegiant Air
Deal found 7/29$621
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/303:49 pmDSM - LEX
1 stop16h 21mMultiple Airlines
jeu. 7/318:56 pmLEX - DSM
2 stops22h 09mMultiple Airlines
Deal found 7/29$667

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juillet 30, 2025.
Use the filters below to find and compare flights from Des Moines to Lexington that are best for you.

Fly from

Des Moines

Fly to

Lexington

Route

Depart

Return

Price

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

lun. 8/25

10:47 am-6:07 pm

1 stop6h 20m

Lexington Blue Grass

lun. 9/1

7:10 am-1:27 pm

1 stop7h 17m

$249

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

lun. 8/25

3:21 pm-11:00 pm

2 stops6h 39m

Lexington Blue Grass

lun. 9/1

6:00 am-8:37 am

1 stop3h 37m

$254

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

jeu. 10/16

6:36 pm-11:59 pm

1 stop4h 23m

Lexington Blue Grass

lun. 10/20

6:01 pm-9:50 pm

1 stop4h 49m

$398

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

ven. 9/12

6:30 pm-11:47 pm

1 stop4h 17m

$211

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

ven. 9/12

5:10 am-3:06 pm

2 stops8h 56m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Des Moines to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Lexington

What is the cheapest month to book a flight from Des Moines to Lexington?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Lexington (average of $303). Flying from Des Moines to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Lexington

Get insights into the airlines that provide service to Lexington. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lexington. Reviews last updated juillet 30, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Des Moines to Lexington have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Lexington round-trip?

    Delta, at $249, was found to be the cheapest airline from Des Moines to Lexington.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Des Moines to Lexington for 30% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to Lexington that include hotel bookings?

    Yes. In addition to deals on Des Moines to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Lexington.

  • Can I find deals for business class flights from Des Moines to Lexington?

    Yes. Cheapflights offers flight deals from Des Moines to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Lexington?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Lexington (average of $303). Flying from Des Moines to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Georgetown
Danville
Berea

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Top 3 airlines flying from Des Moines to Lexington

Discover the top 3 airlines that operate flights from Des Moines to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juillet 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$358FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$225Average$388FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$418FlexibilityNo cancel feeOn-timeN/A

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