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$518+ Cheap flights from Tyler to Knoxville (TYR - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYR — TYS
May 3 — May 101
Sun 5/3
Sun 5/10
1 adult, Economy
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Cheap flight deals from Tyler to Knoxville

Cheapest flights from Tyler to Knoxville
Explore the most affordable flight options available from Tyler to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.

This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:55 pm
TYR
-
TYS
1 stop5h 01m
American Airlines
Sat 4/181:20 pm
TYS
-
TYR
1 stop5h 05m
American Airlines
Deal found 3/30$518
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:35 pm
TYR
-
TYS
1 stop4h 16m
American Airlines
Tue 4/71:20 pm
TYS
-
TYR
1 stop5h 05m
American Airlines
Deal found 4/2$555
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:26 am
TYR
-
TYS
1 stop4h 11m
American Airlines
Mon 4/65:40 am
TYS
-
TYR
1 stop5h 16m
American Airlines
Deal found 3/31$592
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
TYR
-
TYS
2 stops8h 38m
American Airlines
Mon 4/203:58 pm
TYS
-
TYR
2 stops8h 49m
American Airlines
Deal found 4/1$695

Find flight deals from Tyler to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Tyler (TYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$518
(American Airlines)
Provider with most accurate pricing for Tyler Pounds Field-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tyler Pounds Field-Knoxville McGhee Tyson flights.
Search Deals
From Tyler Pounds Field to Knoxville McGhee Tyson
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tyler to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Tyler to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Tue 4/14

6:00 am-12:30 pm

1 stop5h 30m

Knoxville McGhee Tyson

Sat 4/18

8:00 am-5:25 pm

2 stops10h 25m

$524
Quickest round-trip

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Thu 4/16

6:00 am-12:30 pm

1 stop5h 30m

Knoxville McGhee Tyson

Mon 4/20

6:00 am-10:11 am

1 stop5h 11m

$592

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Sorted by cheapest first

Compare providers for flights from Tyler to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tyler to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Tyler-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tyler-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tyler-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Tyler-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tyler-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Tyler to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Tyler with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tyler to Knoxville

What is the cheapest month to book a flight from Tyler to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Tyler to Knoxville (average of $205). Flying from Tyler to Knoxville in March is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 3, 2026.
Peruse reviews from past customers who have flown with American Airlines from Tyler to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,551 reviews

Boarding

7.5

Comfort

7.2

Crew

7.9

Entertainment

6.9

Overall

7.1

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.1
Good
11,551 reviews
American Airlines
7.1
Good
11,551 reviews

Boarding

7.5

Comfort

7.2

Crew

7.9

Entertainment

6.9

Overall

7.1

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Tyler to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tyler to Knoxville?

    For as low as $524, American Airlines can have you in Knoxville from Tyler in 5h 30m. Tyler and Knoxville are separated by a distance of 694 mi.

  • Can I find deals for flights from Tyler to Knoxville that include hotel bookings?

    Yes. In addition to deals on Tyler to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tyler to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tyler to Knoxville.

  • Can I find deals for business class flights from Tyler to Knoxville?

    Yes. Cheapflights offers flight deals from Tyler to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tyler to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Tyler to Knoxville (average of $205). Flying from Tyler to Knoxville in March is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top airline flying from Tyler to Knoxville

Discover the top airline that operate flights from Tyler to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$360Average$428FlexibilityNo cancel feeOn-time71%

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