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$95+ Cheap flights from Tampa to Knoxville (TPA - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — TYS
Aug 2 — Aug 91
Sat 8/2
Sat 8/9
1 adult, Economy
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Cheapflights Tip: The best prices from Tampa to Knoxville McGhee Tyson are usually found in December or January, booked 89 days in advance, depart on a Saturday or Wednesday and return on a Friday

Cheap flight deals from Tampa to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2025.

Round-trip from

$218
(Mytrip)

One-way from

$95
(Mytrip)

Popular in

May

Cheapest in

December

Average price

$272

Good round-trip deal

$97 or less

Good one-way deal

$62 or less
From Tampa to Knoxville McGhee Tyson
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One-way flight from Tampa to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Tampa to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Tampa to Knoxville McGhee Tyson.
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Find flight deals from Tampa to Knoxville

Cheapest flights from Tampa to Knoxville
Explore the most affordable flight options available from Tampa to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

This Mytrip deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/610:25 pmTPA - TYS
1 stop12h 53mMultiple Airlines
Fri 9/128:49 pmTYS - TPA
1 stop10h 30mMultiple Airlines
Deal found 7/27$218
This Frontier deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/177:01 amTPA - TYS
1 stop9h 28mFrontier
Sun 8/248:33 pmTYS - TPA
1 stop8h 58mFrontier
Deal found 7/27$238
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/263:05 pmTPA - TYS
1 stop3h 58mDelta
Wed 9/35:45 amTYS - TPA
1 stop5h 42mDelta
Deal found 7/27$249
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2911:59 amTPA - TYS
1 stop6h 03mAmerican Airlines
Tue 8/1212:03 pmTYS - TPA
1 stop3h 30mAmerican Airlines
Deal found 7/25$299
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:28 pmTPA - TYS
1 stop5h 29mUnited Airlines
Sat 9/277:00 amTYS - TPA
1 stop7h 59mUnited Airlines
Deal found 7/26$319

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2025.
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

Tampa

Fly to

Knoxville

Route

Depart

Return

Price

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 9/6

10:25 pm-11:18 am

1 stop12h 53m

Knoxville McGhee Tyson

Fri 9/12

8:49 pm-7:19 am

1 stop10h 30m

$218

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sun 8/17

7:01 am-4:29 pm

1 stop9h 28m

Knoxville McGhee Tyson

Sun 8/24

8:33 pm-5:31 am

1 stop8h 58m

$238

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Tue 8/26

11:14 am-3:34 pm

1 stop4h 20m

Knoxville McGhee Tyson

Tue 9/2

5:45 am-9:51 am

1 stop4h 06m

$249

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 8/2

8:10 am-2:25 pm

1 stop6h 15m

Knoxville McGhee Tyson

Tue 8/5

2:48 pm-8:20 pm

1 stop5h 32m

$309

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 9/3

6:00 am-3:41 pm

1 stop9h 41m

$95

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sun 8/3

7:01 am-4:29 pm

1 stop9h 28m

$119

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 10/1

11:15 am-5:03 pm

1 stop5h 48m

$150

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Mon 8/11

11:49 am-8:01 pm

1 stop8h 12m

$262

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Fri 8/15

9:00 am-5:49 pm

2 stops32h 49m

$424

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sun 8/3

10:12 am-9:03 pm

2 stops10h 51m

$590

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Tampa to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Knoxville

How far ahead should I book a flight from Tampa to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Tampa to Knoxville. Price data was last updated on July 25, 2025.

To ensure you get the cheapest price possible for a flight from Tampa to Knoxville, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Tampa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $295). Flying from Tampa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to TYS?

Find hourly flight availability from Tampa to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2025.

It’s typically best to fly out from Tampa to Knoxville in the afternoon. Doing so could potentially save you 49% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Tampa to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Tampa to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Tampa to Knoxville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

What’s the top layover airport for flights from Tampa to Knoxville?

Share of 1-stop round-trip flights from Tampa to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.

Houston (IAH) – chosen by Cheapflights users on 50% of 1-stop itineraries from Tampa to Knoxville on Cheapflights.

What’s the cheapest layover airport for flights from Tampa to Knoxville?

Average round-trip fare for 1-stop flights from Tampa to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Washington, D.C. (IAD) is the most affordable 1-stop option, with an average round-trip price of $328.

What’s the fastest layover option from Tampa to Knoxville?

Shortest average travel time for 1-stop one-way flights from Tampa to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Washington, D.C. (IAD) have the shortest average one-way travel time for 1-stop routes: 3h 01m.

Which airport typically offers the quickest layover for flights from Tampa to Knoxville?

Average layover duration for 1-stop one-way flights from Tampa to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Washington, D.C. (IAD) offer the fastest connection on this route, with an average layover time of 1h 11m.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 28, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Tampa to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,971 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,893 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Frontier
5.9
Fair
3,238 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Crew

8.5

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Tampa to Knoxville round-trip?

    Currently priced at $238, Frontier will fly you from Tampa to Knoxville and back. In addition to Frontier, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $249 and $259, respectively. These flights start at 23% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Tampa to Knoxville one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $119. Users have also found prices from $150 and $262 on Delta and United Airlines, respectively.

  • Can I find deals for flights from Tampa to Knoxville that include hotel bookings?

    Yes. In addition to deals on Tampa to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Knoxville.

  • Can I find deals for business class flights from Tampa to Knoxville?

    Yes. Cheapflights offers flight deals from Tampa to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $295). Flying from Tampa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Tampa to Knoxville

Discover the top 4 airlines that operate flights from Tampa to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$86Average$135FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$177Average$372FlexibilityNo cancel feeOn-time69%
DeltaCheapest$208Average$329FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$237Average$357FlexibilityNo cancel feeOn-time71%

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