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$81+ Cheap flights from Tampa to Knoxville (TPA - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Tampa to Knoxville McGhee Tyson are usually found in January or February, booked 71 days in advance, depart on a Friday or Wednesday and return on a Friday

Cheap flight deals from Tampa to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$175
(American Airlines)

One-way from

$81
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$348

Good round-trip deal

$121 or less

Good one-way deal

$57 or less
From Tampa to Knoxville McGhee Tyson
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One-way flight from Tampa to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Tampa to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Tampa to Knoxville McGhee Tyson.
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Find flight deals from Tampa to Knoxville

Cheapest flights from Tampa to Knoxville
Explore the most affordable flight options available from Tampa to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:47 pmTPA - TYS
1 stop4h 16mAmerican Airlines
Tue 10/75:00 amTYS - TPA
1 stop5h 18mAmerican Airlines
Deal found 9/10$175
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/254:44 pmTPA - TYS
1 stop6h 23mDelta
Wed 12/35:25 amTYS - TPA
1 stop3h 35mDelta
Deal found 9/9$177
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/204:44 pmTPA - TYS
1 stop6h 32mMultiple Airlines
Fri 10/245:59 pmTYS - TPA
1 stop20h 09mMultiple Airlines
Deal found 9/11$185
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:33 pmTPA - TYS
1 stop9h 04mMultiple Airlines
Sun 12/145:23 pmTYS - TPA
2 stops28h 05mMultiple Airlines
Deal found 9/9$190
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:46 amTPA - TYS
1 stop5h 17mMultiple Airlines
Sun 12/75:23 pmTYS - TPA
1 stop24h 51mMultiple Airlines
Deal found 9/11$207
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:26 pmTPA - TYS
1 stop18h 40mMultiple Airlines
Sun 10/55:44 pmTYS - TPA
1 stop4h 22mMultiple Airlines
Deal found 9/9$213
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:28 amTPA - TYS
1 stop10h 13mMultiple Airlines
Thu 10/95:44 pmTYS - TPA
1 stop4h 22mMultiple Airlines
Deal found 9/11$219
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/41:06 pmTPA - TYS
1 stop3h 43mAmerican Airlines
Mon 10/68:37 pmTYS - TPA
1 stop3h 29mAmerican Airlines
Deal found 9/10$223
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:39 pmTPA - TYS
1 stop6h 28mAmerican Airlines
Fri 10/178:37 pmTYS - TPA
1 stop3h 32mAmerican Airlines
Deal found 9/10$224
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:12 amTPA - TYS
1 stop3h 39mDelta
Tue 12/97:39 amTYS - TPA
1 stop7h 41mDelta
Deal found 9/10$225
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:26 pmTPA - TYS
1 stop11h 52mMultiple Airlines
Sun 10/55:44 pmTYS - TPA
1 stop4h 22mMultiple Airlines
Deal found 9/9$227
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:26 pmTPA - TYS
1 stop18h 40mMultiple Airlines
Mon 10/610:46 amTYS - TPA
1 stop11h 11mMultiple Airlines
Deal found 9/10$231

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

Tampa

Fly to

Knoxville

Route

Depart

Return

Price

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 10/25

7:00 am-10:28 am

1 stop3h 28m

Knoxville McGhee Tyson

Sat 12/6

8:45 am-2:57 pm

1 stop6h 12m

$177

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 2/18

4:45 pm-9:43 pm

1 stop4h 58m

Knoxville McGhee Tyson

Sat 2/21

10:05 am-1:42 pm

1 stop3h 37m

$177

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Mon 10/20

4:44 pm-11:16 pm

1 stop6h 32m

Knoxville McGhee Tyson

Fri 10/24

5:59 pm-2:08 pm

1 stop20h 09m

$185

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 12/6

1:53 pm-6:59 pm

1 stop5h 06m

Knoxville McGhee Tyson

Mon 12/8

7:59 pm-12:17 am

1 stop4h 18m

$225

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 2/21

9:45 am-3:40 pm

1 stop5h 55m

Knoxville McGhee Tyson

Sun 3/1

8:21 pm-12:08 am

1 stop3h 47m

$237

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sun 10/26

6:20 am-11:04 am

1 stop4h 44m

Knoxville McGhee Tyson

Wed 12/3

5:25 am-10:04 am

1 stop4h 39m

$238

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Mon 10/27

10:00 am-1:42 pm

1 stop3h 42m

Knoxville McGhee Tyson

Sat 12/6

12:49 pm-8:59 pm

1 stop8h 10m

$238

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Tue 10/28

6:20 am-11:04 am

1 stop4h 44m

Knoxville McGhee Tyson

Mon 12/1

8:05 pm-12:15 am

1 stop4h 10m

$238

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 10/25

4:44 pm-11:07 pm

1 stop6h 23m

Knoxville McGhee Tyson

Tue 12/2

2:38 pm-7:03 pm

1 stop4h 25m

$238

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Mon 10/6

6:42 am-4:41 pm

2 stops9h 59m

Knoxville McGhee Tyson

Thu 10/9

5:44 pm-10:06 pm

1 stop4h 22m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 23 results
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Best time to book a flight from Tampa to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Knoxville

How far ahead should I book a flight from Tampa to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Tampa to Knoxville. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Tampa to Knoxville, you should look to book at least 71 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Tampa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $294). Flying from Tampa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to TYS?

Find hourly flight availability from Tampa to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Tampa to Knoxville at noon. Doing so could potentially save you 12% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Tampa to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Tampa to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Tampa to Knoxville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Tampa to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Allegiant Air
7.2
Good
702 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tampa to Knoxville?

    Departing from Tampa to Knoxville will take you 3h 28m. The distance between Tampa and Knoxville is about 547 mi.

  • What are the cheapest airlines flying from Tampa to Knoxville round-trip?

    Currently priced at $84, Allegiant Air will fly you from Tampa to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and Delta - these airlines can fly you to your destination from $177 and $208, respectively. These flights start at 73% lower than the current average price 3 months from now.

  • Can I find deals for flights from Tampa to Knoxville that include hotel bookings?

    Yes. In addition to deals on Tampa to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Knoxville.

  • Can I find deals for business class flights from Tampa to Knoxville?

    Yes. Cheapflights offers flight deals from Tampa to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $294). Flying from Tampa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Tampa to Knoxville

Discover the top 4 airlines that operate flights from Tampa to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$84Average$134FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$177Average$398FlexibilityNo cancel feeOn-time69%
DeltaCheapest$208Average$327FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$245Average$348FlexibilityNo cancel feeOn-time71%

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