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Knoxville

$431+ Cheap flights from South America to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — TYS
jun. 23 — jun. 301
lun. 6/23
lun. 6/30
1 adult, Economy
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Cheap flight deals from South America to Knoxville

Keep the following information in mind while searching for South America to Knoxville flight deals. Data was last updated junio 18, 2025.

Round-trip from

$614
(Mytrip)

One-way from

$431
(Kiwi.com)
From South America to Knoxville McGhee Tyson
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One-way flight from South America to Knoxville McGhee Tyson
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Find flight deals from South America to Knoxville

Cheapest flights from South America to Knoxville
Explore the most affordable flight options available from South America to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 18, 2025.

This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/86:00 amUIO - TYS
3 stops36h 56mMultiple Airlines
lun. 8/2511:24 amTYS - UIO
3 stops16h 21mMultiple Airlines
Deal found 6/16$614
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/154:15 amGYE - TYS
3 stops34h 04mMultiple Airlines
mar. 7/225:45 amTYS - GYE
2 stops21h 20mMultiple Airlines
Deal found 6/16$616
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/158:31 amGYE - TYS
2 stops37h 56mUnited Airlines
mar. 7/227:00 amTYS - GYE
2 stops29h 17mUnited Airlines
Deal found 6/16$620
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/171:35 amUIO - TYS
2 stops46h 07mUnited Airlines
jue. 1/227:00 amTYS - UIO
2 stops17h 30mUnited Airlines
Deal found 6/16$623
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/89:11 amUIO - TYS
2 stops24h 57mDelta
mar. 8/2611:54 amTYS - UIO
1 stop9h 06mDelta
Deal found 6/16$710
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1712:40 amUIO - TYS
1 stop23h 09mAmerican Airlines
jue. 1/227:03 amTYS - UIO
1 stop14h 52mAmerican Airlines
Deal found 6/16$722
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/228:20 amGYE - TYS
1 stop14h 25mAmerican Airlines
lun. 9/296:10 pmTYS - GYE
2 stops26h 38mAmerican Airlines
Deal found 6/16$735
This SmartFares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/97:09 pmUIO - TYS
2 stops27h 50mLATAM Airlines
mar. 8/2611:54 amTYS - UIO
1 stop9h 06mLATAM Airlines
Deal found 6/18$768
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/72:30 amUIO - TYS
2 stops19h 07mAvianca
mar. 8/267:25 pmTYS - UIO
2 stops32h 20mAvianca
Deal found 6/16$792
This Mytrip deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/46:10 amSCL - TYS
3 stops33h 55mMultiple Airlines
lun. 8/1812:45 pmTYS - SCL
3 stops33h 45mMultiple Airlines
Deal found 6/17$814
This Avianca deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/103:35 amGYE - TYS
2 stops18h 02mAvianca
mar. 7/155:45 amTYS - GYE
2 stops21h 20mAvianca
Deal found 6/17$826
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/18:15 amSCL - TYS
2 stops16h 12mDelta
vie. 10/1010:05 amTYS - SCL
1 stop19h 55mDelta
Deal found 6/16$885

Cheapflights Fare Finder

Customize your flight search to find flights from South America to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 18, 2025.
Use the filters below to find and compare flights from South America to Knoxville that are best for you.

Fly from

South America

Fly to

Knoxville

Route

Depart

Return

Price

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

vie. 8/8

6:00 am-7:56 pm

3 stops36h 56m

Knoxville McGhee Tyson

lun. 8/25

11:24 am-2:45 am

3 stops16h 21m

$614

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mar. 7/15

4:15 am-3:19 pm

3 stops34h 04m

Knoxville McGhee Tyson

mar. 7/22

5:45 am-2:05 am

2 stops21h 20m

$616

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mar. 7/15

8:31 am-11:27 pm

2 stops37h 56m

Knoxville McGhee Tyson

mar. 7/22

7:00 am-11:17 am

2 stops29h 17m

$620

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

vie. 8/8

9:11 am-11:08 am

2 stops24h 57m

Knoxville McGhee Tyson

mar. 8/26

11:54 am-8:00 pm

1 stop9h 06m

$710

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

lun. 9/22

8:20 am-11:45 pm

1 stop14h 25m

Knoxville McGhee Tyson

lun. 9/29

6:10 pm-7:48 pm

2 stops26h 38m

$735

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

sáb. 8/9

7:09 pm-11:59 pm

2 stops27h 50m

Knoxville McGhee Tyson

mar. 8/26

11:54 am-8:00 pm

1 stop9h 06m

$768

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

jue. 8/7

2:30 am-10:37 pm

2 stops19h 07m

Knoxville McGhee Tyson

mar. 8/26

7:25 pm-2:45 am

2 stops32h 20m

$792

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

jue. 8/7

12:35 am-10:17 am

2 stops56h 42m

Knoxville McGhee Tyson

vie. 8/29

9:55 am-11:25 pm

2 stops38h 30m

$802

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

lun. 8/4

6:10 am-4:05 pm

3 stops33h 55m

Knoxville McGhee Tyson

lun. 8/18

12:45 pm-10:30 pm

3 stops33h 45m

$814

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

sáb. 8/9

6:09 am-10:15 pm

1 stop15h 06m

Knoxville McGhee Tyson

mar. 8/26

7:00 am-12:05 am

1 stop18h 05m

$826

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/16

Showing 1-10 of 17 results
1
2

Best time to book a flight from South America to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South America to Knoxville

What is the cheapest month to book a flight from South America to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South America to Knoxville (average of $296). Flying from South America to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SA to TYS?

Find hourly flight availability from South America to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 18, 2025.

When flying from South America to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated junio 18, 2025.
Delta
8.0
Very good
7,964 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,787 reviews
Delta
8.0
Very good
7,964 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,810 reviews
Delta
8.0
Very good
7,964 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,350 reviews
Delta
8.0
Very good
7,964 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South America to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from South America?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from South America to Knoxville.

  • What are the most popular routes from South America to Knoxville?

    When deciding which route to take from South America to Knoxville consider Quito Mariscal Sucr - Knoxville McGhee Tyson, Guayaquil Jose Joaquin de Olmedo - Knoxville McGhee Tyson or Santiago Arturo Merino Benitez - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from South America to Knoxville that include hotel bookings?

    Yes. In addition to deals on South America to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South America to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to Knoxville.

  • Can I find deals for business class flights from South America to Knoxville?

    Yes. Cheapflights offers flight deals from South America to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South America to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South America to Knoxville (average of $296). Flying from South America to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South America?

Book flights to South America if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Oak Ridge
Alcoa
Murphy

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Alternative routes for South America to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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