$100+ Cheap flights from San Francisco to Knoxville (SFO - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
Apr 6 — Apr 131
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from San Francisco to KnoxvilleExplore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
Explore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Thu 4/304:28 pm
TYS
- SFO
1 stop19h 45m
Frontier
Deal found 3/6![Frontier logo]()
$211
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:00 pm
SFO
- TYS
1 stop15h 28m
Frontier
Mon 4/134:20 pm
TYS
- SFO
1 stop11h 08m
Frontier
Deal found 3/5![Frontier logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
SFO
- TYS
1 stop30h 33m
Multiple Airlines
Thu 5/149:40 pm
TYS
- SFO
2 stops22h 14m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$307
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- TYS
1 stop10h 13m
Frontier
Wed 7/158:08 pm
TYS
- SFO
1 stop7h 18m
Frontier
Deal found 3/6![Frontier logo]()
$310
This Frontier deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
SFO
- TYS
1 stop6h 25m
Frontier
Fri 3/274:20 pm
TYS
- SFO
1 stop11h 08m
Frontier
Deal found 3/4![Frontier logo]()
$320
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:00 am
SFO
- TYS
1 stop7h 06m
United Airlines
Wed 4/157:20 pm
TYS
- SFO
1 stop8h 57m
United Airlines
Deal found 3/5![United Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:52 pm
SFO
- TYS
1 stop7h 16m
United Airlines
Sat 4/187:05 am
TYS
- SFO
1 stop8h 13m
United Airlines
Deal found 3/3![United Airlines logo]()
$329
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
SFO
- TYS
1 stop6h 28m
Frontier
Fri 4/104:20 pm
TYS
- SFO
1 stop11h 08m
Frontier
Deal found 3/5![Frontier logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:29 pm
SFO
- TYS
2 stops14h 55m
Multiple Airlines
Thu 4/164:28 pm
TYS
- SFO
1 stop10h 59m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:52 pm
SFO
- TYS
1 stop7h 16m
United Airlines
Thu 4/167:20 pm
TYS
- SFO
1 stop8h 57m
United Airlines
Deal found 3/5![United Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:28 pm
SFO
- TYS
1 stop9h 47m
American Airlines
Tue 4/286:00 am
TYS
- SFO
1 stop8h 05m
American Airlines
Deal found 3/4![American Airlines logo]()
$339
Best flights from San Francisco to KnoxvilleDiscover carefully curated flight deals from San Francisco to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
Discover carefully curated flight deals from San Francisco to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:10 am
SFO
- TYS
1 stop6h 25m
Southwest
Tue 4/217:05 am
TYS
- SFO
2 stops11h 15m
Southwest
Deal found 3/3![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:38 pm
SFO
- TYS
1 stop9h 12m
United Airlines
Tue 4/287:00 am
TYS
- SFO
2 stops13h 12m
United Airlines
Deal found 3/2![United Airlines logo]()
$477
This Alaska Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:45 am
SFO
- TYS
2 stops10h 11m
Alaska Airlines
Fri 4/244:09 pm
TYS
- SFO
2 stops9h 52m
Alaska Airlines
Deal found 3/4![Alaska Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:38 pm
SFO
- TYS
1 stop9h 12m
United Airlines
Sat 5/97:00 am
TYS
- SFO
2 stops14h 56m
United Airlines
Deal found 3/2![United Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:33 am
SFO
- TYS
1 stop7h 28m
United Airlines
Fri 4/247:00 am
TYS
- SFO
1 stop8h 03m
United Airlines
Deal found 3/3![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:52 pm
SFO
- TYS
1 stop7h 16m
United Airlines
Sat 5/27:00 am
TYS
- SFO
2 stops14h 56m
United Airlines
Deal found 3/4![United Airlines logo]()
$505
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:15 am
SFO
- TYS
2 stops13h 26m
United Airlines
Mon 4/135:53 pm
TYS
- SFO
1 stop10h 42m
United Airlines
Deal found 3/6![United Airlines logo]()
$560
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:45 pm
SFO
- TYS
1 stop9h 04m
United Airlines
Wed 3/257:00 am
TYS
- SFO
1 stop8h 06m
United Airlines
Deal found 3/4![United Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:45 pm
SFO
- TYS
2 stops13h 21m
United Airlines
Mon 4/277:20 pm
TYS
- SFO
1 stop8h 57m
United Airlines
Deal found 3/2![United Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:10 am
SFO
- TYS
1 stop8h 13m
United Airlines
Sat 5/167:05 am
TYS
- SFO
2 stops13h 07m
United Airlines
Deal found 3/5![United Airlines logo]()
$626
Last-minute flights from San Francisco to KnoxvilleDiscover last-minute flight deals from San Francisco to Knoxville. Data last updated March 7, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Knoxville. Data last updated March 7, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
SFO
- TYS
1 stop6h 25m
Frontier
Fri 3/274:20 pm
TYS
- SFO
1 stop11h 08m
Frontier
Deal found 3/4![Frontier logo]()
$320
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:00 pm
SFO
- TYS
1 stop15h 28m
Frontier
Mon 4/134:20 pm
TYS
- SFO
1 stop11h 08m
Frontier
Deal found 3/5![Frontier logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/510:57 pm
SFO
- TYS
2 stops38h 07m
Multiple Airlines
Mon 4/134:20 pm
TYS
- SFO
1 stop11h 08m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$341
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
SFO
- TYS
1 stop6h 28m
Frontier
Fri 4/104:20 pm
TYS
- SFO
1 stop11h 08m
Frontier
Deal found 3/5![Frontier logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:52 pm
SFO
- TYS
1 stop7h 16m
United Airlines
Sat 4/187:05 am
TYS
- SFO
1 stop8h 13m
United Airlines
Deal found 3/3![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:55 pm
SFO
- TYS
1 stop10h 05m
Southwest
Sat 4/1812:20 pm
TYS
- SFO
2 stops12h 00m
Southwest
Deal found 3/3![Southwest logo]()
$340
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:00 am
SFO
- TYS
1 stop7h 06m
United Airlines
Wed 4/157:20 pm
TYS
- SFO
1 stop8h 57m
United Airlines
Deal found 3/5![United Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:29 pm
SFO
- TYS
2 stops14h 55m
Multiple Airlines
Thu 4/164:28 pm
TYS
- SFO
1 stop10h 59m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:52 pm
SFO
- TYS
1 stop7h 16m
United Airlines
Thu 4/167:20 pm
TYS
- SFO
1 stop8h 57m
United Airlines
Deal found 3/5![United Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:28 pm
SFO
- TYS
1 stop9h 47m
American Airlines
Tue 4/286:00 am
TYS
- SFO
1 stop8h 05m
American Airlines
Deal found 3/4![American Airlines logo]()
$339
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Thu 4/304:28 pm
TYS
- SFO
1 stop19h 45m
Frontier
Deal found 3/6![Frontier logo]()
$211
One-way flights from San Francisco to KnoxvilleSearch for one-way flight options from San Francisco to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
Search for one-way flight options from San Francisco to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
This Priceline deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Deal found 3/3![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
SFO
- TYS
1 stop30h 33m
Frontier
Deal found 3/5![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:40 am
SFO
- TYS
3 stops52h 01m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$149
This Frontier deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
- TYS
1 stop10h 13m
Frontier
Deal found 3/4![Frontier logo]()
$151
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:45 am
SFO
- TYS
1 stop9h 29m
United Airlines
Deal found 3/5![United Airlines logo]()
$165
Find flight deals from San Francisco to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (CheapOair) |
One-way from | $100 (Priceline) |
Popular in | November |
Cheapest in | August |
Average price | $517 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
Use the filters below to find and compare flights from San Francisco to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sat 4/18
10:10 am-7:35 pm
1 stop6h 25m
Knoxville McGhee Tyson
Tue 4/21
7:05 am-3:20 pm
2 stops11h 15m
$417
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Fri 4/24
10:38 pm-10:50 am
1 stop9h 12m
Knoxville McGhee Tyson
Tue 4/28
7:00 am-5:12 pm
2 stops13h 12m
$477
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Fri 4/24
10:38 pm-10:50 am
1 stop9h 12m
Knoxville McGhee Tyson
Sat 5/9
7:00 am-6:56 pm
2 stops14h 56m
$477
Quickest round-trip
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Tue 4/21
6:33 am-5:01 pm
1 stop7h 28m
Knoxville McGhee Tyson
Fri 4/24
7:00 am-12:03 pm
1 stop8h 03m
$483
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sun 4/26
11:52 pm-10:08 am
1 stop7h 16m
Knoxville McGhee Tyson
Sat 5/2
7:00 am-6:56 pm
2 stops14h 56m
$505
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Tue 4/21
10:45 am-11:56 pm
2 stops10h 11m
Knoxville McGhee Tyson
Fri 4/24
4:09 pm-11:01 pm
2 stops9h 52m
$548
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Wed 4/8
7:15 am-11:41 pm
2 stops13h 26m
Knoxville McGhee Tyson
Mon 4/13
5:53 pm-1:35 am
1 stop10h 42m
$560
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Mon 3/23
10:45 pm-10:49 am
1 stop9h 04m
Knoxville McGhee Tyson
Wed 3/25
7:00 am-12:06 pm
1 stop8h 06m
$563
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Fri 4/24
10:45 pm-3:06 pm
2 stops13h 21m
Knoxville McGhee Tyson
Mon 4/27
7:20 pm-1:17 am
1 stop8h 57m
$605
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sat 5/2
11:10 am-10:23 pm
1 stop8h 13m
Knoxville McGhee Tyson
Sat 5/16
7:05 am-5:12 pm
2 stops13h 07m
$626
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco with our price prediction graph.
SFO-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Knoxville
How far ahead should I book a flight from San Francisco to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Knoxville. Price data was last updated on March 6, 2026.
Booking 72 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Francisco to Knoxville?
Currently, May is the cheapest month in which you can book a flight from San Francisco to Knoxville (average of $138). Flying from San Francisco to Knoxville in February is currently the most expensive (average of $309). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 7, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Top 4 airlines flying from San Francisco to Knoxville
Discover the top 4 airlines that operate flights from San Francisco to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$89 | Average$267 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$308 | Average$419 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$496 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$541 | FlexibilityNo cancel fee | On-time69% |