$111+ Cheap flights from San Francisco to Knoxville (SFO - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
May 17 — May 241
Round-trip
1 adult, Economy
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Cheapest flights from San Francisco to KnoxvilleExplore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Expedia deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Sun 4/264:28 pm
TYS
- SFO
1 stop19h 45m
Frontier
Deal found 4/13![Frontier logo]()
$250
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Fri 6/58:32 pm
TYS
- SFO
1 stop14h 29m
Frontier
Deal found 4/16![Frontier logo]()
$255
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/259:43 pm
SFO
- TYS
1 stop18h 54m
Frontier
Mon 6/298:32 pm
TYS
- SFO
1 stop18h 11m
Frontier
Deal found 4/14![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:15 pm
SFO
- TYS
2 stops20h 33m
Multiple Airlines
Fri 5/151:43 pm
TYS
- SFO
1 stop21h 47m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$295
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
SFO
- TYS
1 stop27h 41m
Frontier
Mon 5/118:32 pm
TYS
- SFO
1 stop18h 15m
Frontier
Deal found 4/14![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Tue 6/25:00 pm
TYS
- SFO
1 stop20h 41m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Mon 6/18:32 pm
TYS
- SFO
1 stop30h 51m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:36 am
SFO
- TYS
2 stops23h 16m
Multiple Airlines
Mon 6/87:27 pm
TYS
- SFO
1 stop18h 07m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Sun 5/317:00 am
TYS
- SFO
1 stop28h 01m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:56 pm
SFO
- TYS
2 stops18h 37m
Multiple Airlines
Tue 6/25:00 pm
TYS
- SFO
1 stop20h 41m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- TYS
1 stop10h 33m
Multiple Airlines
Mon 6/15:30 pm
TYS
- SFO
2 stops26h 00m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$342
Best flights from San Francisco to KnoxvilleDiscover carefully curated flight deals from San Francisco to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from San Francisco to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:45 pm
SFO
- TYS
1 stop7h 11m
Delta
Tue 6/211:44 am
TYS
- SFO
1 stop9h 05m
Delta
Deal found 4/12![Delta logo]()
$382
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:55 pm
SFO
- TYS
2 stops14h 30m
Southwest
Tue 9/157:00 am
TYS
- SFO
1 stop12h 25m
Southwest
Deal found 4/12![Southwest logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:05 pm
SFO
- TYS
1 stop8h 37m
United Airlines
Thu 5/285:45 am
TYS
- SFO
1 stop9h 52m
United Airlines
Deal found 4/15![United Airlines logo]()
$499
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2311:56 pm
SFO
- TYS
1 stop7h 24m
Delta
Mon 7/273:54 pm
TYS
- SFO
1 stop9h 55m
Delta
Deal found 4/13![Delta logo]()
$464
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:55 am
SFO
- TYS
2 stops10h 45m
Southwest
Thu 5/282:45 pm
TYS
- SFO
2 stops10h 40m
Southwest
Deal found 4/16![Southwest logo]()
$498
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
SFO
- TYS
2 stops11h 20m
Southwest
Mon 7/137:45 pm
TYS
- SFO
2 stops7h 45m
Southwest
Deal found 4/16![Southwest logo]()
$517
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:30 am
SFO
- TYS
1 stop8h 24m
United Airlines
Thu 5/146:01 pm
TYS
- SFO
1 stop10h 49m
United Airlines
Deal found 4/13![United Airlines logo]()
$625
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
SFO
- TYS
2 stops11h 20m
Southwest
Sun 8/27:00 pm
TYS
- SFO
2 stops8h 10m
Southwest
Deal found 4/12![Southwest logo]()
$613
Last-minute flights from San Francisco to KnoxvilleDiscover last-minute flight deals from San Francisco to Knoxville. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Knoxville. Data last updated April 17, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Sun 4/264:28 pm
TYS
- SFO
1 stop19h 45m
Frontier
Deal found 4/13![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
SFO
- TYS
1 stop27h 41m
Frontier
Mon 5/118:32 pm
TYS
- SFO
1 stop18h 15m
Frontier
Deal found 4/14![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:56 pm
SFO
- TYS
2 stops18h 37m
Multiple Airlines
Tue 6/25:00 pm
TYS
- SFO
1 stop20h 41m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:56 pm
SFO
- TYS
2 stops18h 37m
Frontier
Mon 6/18:32 pm
TYS
- SFO
1 stop30h 51m
Frontier
Deal found 4/12![Frontier logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- TYS
1 stop10h 33m
Multiple Airlines
Mon 6/15:30 pm
TYS
- SFO
2 stops26h 00m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Tue 6/25:00 pm
TYS
- SFO
1 stop20h 41m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Mon 6/18:32 pm
TYS
- SFO
1 stop30h 51m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Sun 5/317:00 am
TYS
- SFO
1 stop28h 01m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:15 pm
SFO
- TYS
2 stops20h 33m
Multiple Airlines
Fri 5/151:43 pm
TYS
- SFO
1 stop21h 47m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/103:33 pm
SFO
- TYS
2 stops27h 51m
Multiple Airlines
Thu 5/148:00 am
TYS
- SFO
1 stop11h 30m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$344
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Fri 6/58:32 pm
TYS
- SFO
1 stop14h 29m
Frontier
Deal found 4/16![Frontier logo]()
$255
One-way flights from San Francisco to KnoxvilleSearch for one-way flight options from San Francisco to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from San Francisco to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This Priceline deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
SFO
- TYS
1 stop10h 33m
Frontier
Deal found 4/14![Frontier logo]()
$111
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:52 pm
SFO
- TYS
1 stop27h 32m
Frontier
Deal found 4/14![Frontier logo]()
$117
This Expedia deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Deal found 4/13![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
SFO
- TYS
2 stops30h 41m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$126
This Priceline deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 4/16![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:26 am
SFO
- TYS
3 stops54h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$152
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
SFO
- TYS
1 stop6h 33m
Frontier
Deal found 4/16![Frontier logo]()
$155
This CheapOair deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:52 pm
SFO
- TYS
1 stop27h 41m
Frontier
Deal found 4/12![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
SFO
- TYS
2 stops37h 33m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:25 pm
SFO
- TYS
2 stops47h 08m
Frontier
Deal found 4/16![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:15 pm
SFO
- TYS
2 stops20h 42m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$175
Find flight deals from San Francisco to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $255 (Frontier) |
One-way from | $111 (Priceline) |
Popular in | November |
Cheapest in | August |
Average price | $557 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from San Francisco to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sat 5/9
1:45 pm-11:56 pm
1 stop7h 11m
Knoxville McGhee Tyson
Tue 6/2
11:44 am-5:49 pm
1 stop9h 05m
$382
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Thu 9/10
7:55 pm-1:25 pm
2 stops14h 30m
Knoxville McGhee Tyson
Tue 9/15
7:00 am-4:25 pm
1 stop12h 25m
$439
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Thu 7/23
11:56 pm-10:20 am
1 stop7h 24m
Knoxville McGhee Tyson
Mon 7/27
3:54 pm-10:49 pm
1 stop9h 55m
$464
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Tue 5/26
5:55 am-7:40 pm
2 stops10h 45m
Knoxville McGhee Tyson
Thu 5/28
2:45 pm-10:25 pm
2 stops10h 40m
$498
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sun 5/24
11:05 pm-10:42 am
1 stop8h 37m
Knoxville McGhee Tyson
Thu 5/28
5:45 am-12:37 pm
1 stop9h 52m
$499
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Tue 6/23
6:00 am-8:20 pm
2 stops11h 20m
Knoxville McGhee Tyson
Mon 7/13
7:45 pm-12:30 am
2 stops7h 45m
$517
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Wed 7/29
6:00 am-8:20 pm
2 stops11h 20m
Knoxville McGhee Tyson
Sun 8/2
7:00 pm-12:10 am
2 stops8h 10m
$613
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sun 5/10
5:30 am-4:54 pm
1 stop8h 24m
Knoxville McGhee Tyson
Thu 5/14
6:01 pm-1:50 am
1 stop10h 49m
$625
Cheapest one-way
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Wed 6/10
6:00 am-7:37 pm
1 stop10h 37m
$111
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Mon 8/24
6:00 am-7:37 pm
1 stop10h 37m
$125
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Knoxville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco with our price prediction graph.
SFO-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Knoxville
How far ahead should I book a flight from San Francisco to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Knoxville. Price data was last updated on April 10, 2026.
Booking 72 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Francisco to Knoxville?
Currently, August is the cheapest month in which you can book a flight from San Francisco to Knoxville (average of $386). Flying from San Francisco to Knoxville in November is currently the most expensive (average of $573). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 17, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from San Francisco to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
San Francisco and Knoxville flights
Browse other San Francisco and Knoxville flight options. Last updated on April 17, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Knoxville
Discover the top 4 airlines that operate flights from San Francisco to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$89 | Average$267 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$308 | Average$429 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$493 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$536 | FlexibilityNo cancel fee | On-time69% |