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$271+ Cheap flights from Rochester to Knoxville (ROC - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — TYS
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from Rochester to Knoxville

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:15 am
ROC
-
TYS
1 stop4h 06m
Delta
Sat 5/211:02 am
TYS
-
ROC
1 stop4h 20m
Delta
Deal found 2/2$271
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:05 am
ROC
-
TYS
1 stop4h 36m
United Airlines
Sat 6/66:30 am
TYS
-
ROC
2 stops7h 37m
United Airlines
Deal found 2/5$276
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:30 pm
ROC
-
TYS
1 stop5h 17m
Delta
Mon 8/247:20 pm
TYS
-
ROC
1 stop4h 42m
Delta
Deal found 2/3$280
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:25 am
ROC
-
TYS
2 stops26h 35m
Multiple Airlines
Wed 3/114:25 pm
TYS
-
ROC
1 stop17h 08m
Multiple Airlines
Deal found 2/3$286
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:07 am
ROC
-
TYS
1 stop4h 42m
United Airlines
Sat 2/286:45 am
TYS
-
ROC
1 stop6h 58m
United Airlines
Deal found 2/5$289
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:13 am
ROC
-
TYS
1 stop10h 44m
Allegiant Air
Wed 3/114:25 pm
TYS
-
ROC
1 stop17h 08m
Allegiant Air
Deal found 2/3$301
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:49 pm
ROC
-
TYS
1 stop4h 40m
United Airlines
Sat 2/286:45 am
TYS
-
ROC
1 stop6h 58m
United Airlines
Deal found 2/5$304
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:05 am
ROC
-
TYS
2 stops10h 25m
Southwest
Sat 5/27:45 am
TYS
-
ROC
1 stop3h 55m
Southwest
Deal found 2/2$313

Find flight deals from Rochester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Delta)

Popular in

April

Cheapest in

September

Average price

$313
Provider with most accurate pricing for Greater Rochester Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greater Rochester Intl-Knoxville McGhee Tyson flights.
Search Deals
From Greater Rochester Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Fly from

Rochester

Fly to

Knoxville

Route

Depart

Return

Price

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sat 4/25

6:15 am-10:21 am

1 stop4h 06m

Knoxville McGhee Tyson

Sat 5/2

11:02 am-3:22 pm

1 stop4h 20m

$271

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Thu 3/5

9:25 am-12:00 pm

2 stops26h 35m

Knoxville McGhee Tyson

Wed 3/11

4:25 pm-9:33 am

1 stop17h 08m

$286

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Thu 2/26

6:07 am-10:49 am

1 stop4h 42m

Knoxville McGhee Tyson

Sat 2/28

6:45 am-1:43 pm

1 stop6h 58m

$289

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 3/9

1:29 pm-8:47 pm

1 stop7h 18m

Knoxville McGhee Tyson

Thu 3/12

7:00 am-1:45 pm

1 stop6h 45m

$289

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 3/9

5:30 pm-11:50 pm

2 stops6h 20m

Knoxville McGhee Tyson

Thu 3/12

6:10 am-12:59 pm

1 stop6h 49m

$294

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Thu 2/26

12:50 pm-8:20 pm

1 stop7h 30m

Knoxville McGhee Tyson

Sat 2/28

7:38 am-12:19 pm

1 stop4h 41m

$304

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 2/25

2:49 pm-7:29 pm

1 stop4h 40m

Knoxville McGhee Tyson

Sat 2/28

9:40 am-2:14 pm

1 stop4h 34m

$304

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 4/13

10:32 am-10:29 pm

2 stops11h 57m

Knoxville McGhee Tyson

Thu 4/16

7:00 am-1:29 pm

1 stop6h 29m

$309

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sat 4/25

8:05 am-6:30 pm

2 stops10h 25m

Knoxville McGhee Tyson

Sat 5/2

7:45 am-11:40 am

1 stop3h 55m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Compare providers for flights from Rochester to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rochester to Knoxville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Rochester-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rochester-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rochester-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rochester-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rochester-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

How far ahead should I book a flight from Rochester to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Rochester to Knoxville. Price data was last updated on January 30, 2026.

Booking 46 days in advance of your planned departure date is, on average, the best time to get cheap flights from Rochester to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Rochester to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $137). Flying from Rochester to Knoxville in October is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 5, 2026.
Read through reviews of airlines operating flights from Rochester to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,151 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,151 reviews
Delta
7.9
Good
8,151 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,240 reviews
Delta
7.9
Good
8,151 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,237 reviews
Delta
7.9
Good
8,151 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester to Knoxville?

    For as low as $271, Delta can have you in Knoxville from Rochester in 4h 06m. Airlines will cover a distance of 606 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Rochester to Knoxville round-trip?

    Our cheapest airline available from Rochester to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $168 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $248 and $248 round-trip. Delta is currently priced 53% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Rochester to Knoxville one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $134. Users have also found prices from $134 and $184 on Delta and United Airlines, respectively.

  • Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.

  • Can I find deals for business class flights from Rochester to Knoxville?

    Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $137). Flying from Rochester to Knoxville in October is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Rochester to Knoxville

Discover the top 3 airlines that operate flights from Rochester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$353FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$343FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$375FlexibilityNo cancel feeOn-time71%

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