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$102+ Cheap flights from Rochester to Knoxville (ROC - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — TYS
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Rochester Greater Rochester Intl to Knoxville McGhee Tyson are usually found in February or September, booked 83 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Rochester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$271
(Delta)

One-way from

$102
(Kiwi.com)

Popular in

April

Cheapest in

February

Average price

$293
From Rochester Greater Rochester Intl to Knoxville McGhee Tyson
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One-way flight from Rochester Greater Rochester Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Rochester to Knoxville

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:30 amROC - TYS
1 stop6h 47mUnited Airlines
Wed 12/179:40 amTYS - ROC
1 stop4h 37mUnited Airlines
Deal found 9/14$271
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:18 pmROC - TYS
2 stops6h 39mAmerican Airlines
Wed 12/176:00 amTYS - ROC
1 stop5h 26mAmerican Airlines
Deal found 9/14$276
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:22 amROC - TYS
1 stop4h 51mAmerican Airlines
Tue 10/286:03 amTYS - ROC
1 stop5h 23mAmerican Airlines
Deal found 9/15$280
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:20 amROC - TYS
1 stop16h 27mMultiple Airlines
Thu 11/62:55 pmTYS - ROC
1 stop21h 22mMultiple Airlines
Deal found 9/15$295
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:20 amROC - TYS
1 stop27h 36mMultiple Airlines
Sat 10/258:40 amTYS - ROC
1 stop9h 18mMultiple Airlines
Deal found 9/14$303
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amROC - TYS
1 stop4h 45mDelta
Wed 10/296:12 amTYS - ROC
1 stop5h 38mDelta
Deal found 9/14$304
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:23 pmROC - TYS
1 stop5h 44mAmerican Airlines
Mon 12/295:08 pmTYS - ROC
1 stop6h 49mAmerican Airlines
Deal found 9/14$316

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Fly from

Rochester

Fly to

Knoxville

Route

Depart

Return

Price

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Sat 12/13

6:30 am-1:17 pm

1 stop6h 47m

Knoxville McGhee Tyson

Wed 12/17

9:40 am-2:17 pm

1 stop4h 37m

$271

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Sat 12/13

11:33 am-5:12 pm

1 stop5h 39m

Knoxville McGhee Tyson

Wed 12/17

6:00 am-11:26 am

1 stop5h 26m

$271

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Sat 2/21

5:30 pm-9:32 pm

1 stop4h 02m

Knoxville McGhee Tyson

Wed 2/25

7:30 am-11:44 am

1 stop4h 14m

$271

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Sun 11/2

5:20 am-9:47 pm

1 stop16h 27m

Knoxville McGhee Tyson

Thu 11/6

1:16 pm-12:17 pm

2 stops23h 01m

$280

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Mon 11/3

8:00 am-9:55 pm

1 stop13h 55m

Knoxville McGhee Tyson

Thu 11/6

1:16 pm-12:17 pm

2 stops23h 01m

$280

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Fri 12/12

2:24 pm-9:38 pm

1 stop7h 14m

Knoxville McGhee Tyson

Tue 12/16

5:45 pm-11:57 pm

1 stop6h 12m

$280

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Wed 10/22

6:00 am-10:45 am

1 stop4h 45m

Knoxville McGhee Tyson

Wed 10/29

6:12 am-11:50 am

1 stop5h 38m

$304

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Sun 10/12

6:20 am-9:56 am

1 stop27h 36m

Knoxville McGhee Tyson

Sat 10/25

8:40 am-5:58 pm

1 stop9h 18m

$306

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Fri 9/26

6:57 pm-8:41 pm

2 stops25h 44m

$102

RochesterKnoxville

ROC - TYS

ROCTYS

Rochester Greater Rochester Intl

Mon 11/17

1:13 pm-11:14 pm

1 stop10h 01m

$115

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 13 results
1
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Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

How far ahead should I book a flight from Rochester to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Rochester to Knoxville. Price data was last updated on September 12, 2025.

Booking 31 days in advance of your planned departure date is, on average, the best time to get cheap flights from Rochester to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Rochester to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $295). Flying from Rochester to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROC to TYS?

Find hourly flight availability from Rochester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

One of the essential ways to save on airfare from Rochester to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 12% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Rochester to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester to Knoxville?

    For as low as $271, United Airlines can have you in Knoxville from Rochester in 4h 02m. Airlines will cover a distance of 606 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Rochester to Knoxville round-trip?

    Our cheapest airline available from Rochester to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $239 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $248 and $251 round-trip. Delta is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.

  • Can I find deals for business class flights from Rochester to Knoxville?

    Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $295). Flying from Rochester to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Rochester to Knoxville

Discover the top 3 airlines that operate flights from Rochester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$323FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$370FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$251Average$379FlexibilityNo cancel feeOn-time71%

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