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$122+ Cheap flights from Rochester to Knoxville (ROC - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — TYS
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheapflights Tip: The best prices from Greater Rochester Intl to Knoxville McGhee Tyson are usually found in February or September, booked 83 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Find flight deals from Rochester to Knoxville

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:23 pmROC - TYS
1 stop7h 17mAmerican Airlines
Thu 12/116:00 amTYS - ROC
1 stop5h 26mAmerican Airlines
Deal found 10/22$194
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/112:33 pmROC - TYS
1 stop10h 07mMultiple Airlines
Sun 12/75:23 pmTYS - ROC
2 stops24h 23mMultiple Airlines
Deal found 10/21$272
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:23 pmROC - TYS
1 stop5h 05mDelta
Sun 12/77:39 amTYS - ROC
1 stop4h 01mDelta
Deal found 10/22$293
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:30 pmROC - TYS
1 stop7h 03mUnited Airlines
Tue 11/117:20 pmTYS - ROC
1 stop4h 24mUnited Airlines
Deal found 10/21$294
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:37 pmROC - TYS
1 stop5h 18mUnited Airlines
Sun 11/95:45 amTYS - ROC
1 stop4h 12mUnited Airlines
Deal found 10/21$299
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:15 amROC - TYS
2 stops8h 45mAmerican Airlines
Wed 12/106:00 amTYS - ROC
1 stop5h 26mAmerican Airlines
Deal found 10/20$305
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:57 pmROC - TYS
2 stops18h 05mMultiple Airlines
Sun 12/78:30 amTYS - ROC
1 stop9h 16mMultiple Airlines
Deal found 10/22$323

Cheap flight deals from Rochester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$194
(American Airlines)

One-way from

$122
(Kiwi.com)

Popular in

April

Cheapest in

February

Average price

$382
Provider with most accurate pricing for Greater Rochester Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Greater Rochester Intl-Knoxville McGhee Tyson flights.
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From Greater Rochester Intl to Knoxville McGhee Tyson
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One-way flight from Greater Rochester Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Fly from

Rochester

Fly to

Knoxville

Route

Depart

Return

Price

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 12/8

5:15 am-10:50 am

1 stop5h 35m

Knoxville McGhee Tyson

Wed 12/10

6:00 am-11:26 am

1 stop5h 26m

$194

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sat 12/6

6:00 am-10:30 am

1 stop4h 30m

Knoxville McGhee Tyson

Thu 12/11

6:00 am-11:26 am

1 stop5h 26m

$194

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Tue 3/24

5:30 pm-9:32 pm

1 stop4h 02m

Knoxville McGhee Tyson

Tue 3/31

11:55 am-4:59 pm

1 stop5h 04m

$271

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Fri 12/5

6:23 pm-11:28 pm

1 stop5h 05m

Knoxville McGhee Tyson

Sun 12/7

7:39 am-11:40 am

1 stop4h 01m

$293

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Wed 11/5

5:37 pm-10:55 pm

1 stop5h 18m

Knoxville McGhee Tyson

Sun 11/9

5:45 am-9:57 am

1 stop4h 12m

$299

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Sat 1/17

1:26 pm-9:02 pm

1 stop7h 36m

Knoxville McGhee Tyson

Mon 1/19

6:45 am-1:39 pm

1 stop6h 54m

$307

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 2/9

4:00 pm-8:56 pm

1 stop4h 56m

Knoxville McGhee Tyson

Mon 2/16

7:18 am-11:48 am

1 stop4h 30m

$311

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Fri 11/14

6:57 pm-8:16 am

2 stops13h 19m

$122

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 11/24

12:33 pm-10:52 pm

1 stop10h 19m

$123

RochesterKnoxville

ROC - TYS

ROCTYS

Greater Rochester Intl

Mon 12/1

12:33 pm-10:40 pm

1 stop10h 07m

$127

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Showing 1-10 of 16 results
1
2

Compare providers for flights from Rochester to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rochester to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Rochester-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rochester-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rochester-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rochester-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rochester-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

How far ahead should I book a flight from Rochester to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Rochester to Knoxville. Price data was last updated on October 17, 2025.

Booking 28 days in advance of your planned departure date is, on average, the best time to get cheap flights from Rochester to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Rochester to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $144). Flying from Rochester to Knoxville in November is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROC to TYS?

Find hourly flight availability from Rochester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

One of the essential ways to save on airfare from Rochester to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 11% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 23, 2025.
Read through reviews of airlines operating flights from Rochester to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,982 reviews
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,995 reviews
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester to Knoxville?

    For as low as $194, American Airlines can have you in Knoxville from Rochester in 5h 35m. Airlines will cover a distance of 606 mi.

  • What are the cheapest airlines flying from Rochester to Knoxville round-trip?

    Our cheapest airline available from Rochester to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $248 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $248 and $249 round-trip. Delta is currently priced 30% below the average price you’ll pay for this route.

  • Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.

  • Can I find deals for business class flights from Rochester to Knoxville?

    Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Rochester to Knoxville (average of $144). Flying from Rochester to Knoxville in November is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Rochester to Knoxville

Discover the top 3 airlines that operate flights from Rochester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$327FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$366FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$249Average$380FlexibilityNo cancel feeOn-time71%

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