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$110+ Cheap flights from Reagan-National (DCA) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
DCA — TYS
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Washington, D.C. Reagan-National to Knoxville McGhee Tyson are usually found in January or February, booked 90 days in advance, depart on a Saturday or Wednesday and return on a Saturday

Cheap flight deals from Reagan-National to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Reagan-National (DCA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$189
(American Airlines)

One-way from

$110
(Kiwi.com)

Popular in

September

Cheapest in

January

Average price

$409

Good round-trip deal

$279 or less

Good one-way deal

$213 or less
From Washington, D.C. Reagan-National to Knoxville McGhee Tyson
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One-way flight from Washington, D.C. Reagan-National to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 12% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Washington, D.C. Reagan-National to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Washington, D.C. Reagan-National to Knoxville McGhee Tyson.
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Find flight deals from Reagan-National to Knoxville

Cheapest flights from Reagan-National to Knoxville
Explore the most affordable flight options available from Reagan-National to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:59 pmDCA - TYS
Nonstop1h 49mAmerican Airlines
Sun 11/236:06 amTYS - DCA
Nonstop1h 43mAmerican Airlines
Deal found 9/15$189
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/41:55 pmDCA - TYS
Nonstop1h 46mAmerican Airlines
Sat 10/116:03 amTYS - DCA
Nonstop1h 42mAmerican Airlines
Deal found 9/14$194
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:19 amDCA - TYS
Nonstop1h 54mAmerican Airlines
Fri 10/314:41 pmTYS - DCA
Nonstop1h 36mAmerican Airlines
Deal found 9/15$205
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amDCA - TYS
1 stop6h 03mDelta
Tue 10/145:19 pmTYS - DCA
1 stop5h 32mDelta
Deal found 9/14$209
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:20 pmDCA - TYS
1 stop5h 24mDelta
Tue 10/72:55 pmTYS - DCA
1 stop5h 38mDelta
Deal found 9/15$214
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:09 amDCA - TYS
1 stop3h 43mAmerican Airlines
Sat 10/2510:43 amTYS - DCA
Nonstop1h 31mAmerican Airlines
Deal found 9/14$220
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/242:59 pmDCA - TYS
Nonstop1h 50mAmerican Airlines
Wed 10/16:00 amTYS - DCA
Nonstop1h 49mAmerican Airlines
Deal found 9/13$224
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:00 amDCA - TYS
1 stop4h 51mAmerican Airlines
Thu 10/94:41 pmTYS - DCA
Nonstop1h 36mAmerican Airlines
Deal found 9/13$229
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:00 amDCA - TYS
1 stop6h 46mDelta
Tue 12/23:56 pmTYS - DCA
1 stop4h 43mDelta
Deal found 9/15$230

Cheapflights Fare Finder

 
Customize your flight search to find flights from Reagan-National to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Knoxville that are best for you.

Fly from

Reagan-National

Fly to

Knoxville

Route

Depart

Return

Price

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Fri 10/3

7:58 pm-9:41 pm

Nonstop1h 43m

Knoxville McGhee Tyson

Thu 10/9

6:03 am-7:45 am

Nonstop1h 42m

$194

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 10/28

8:19 am-10:13 am

Nonstop1h 54m

Knoxville McGhee Tyson

Fri 10/31

4:41 pm-6:17 pm

Nonstop1h 36m

$205

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 10/7

6:00 am-12:03 pm

1 stop6h 03m

Knoxville McGhee Tyson

Tue 10/14

5:19 pm-10:51 pm

1 stop5h 32m

$209

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 10/4

6:20 pm-11:44 pm

1 stop5h 24m

Knoxville McGhee Tyson

Tue 10/7

5:44 am-9:10 am

1 stop3h 26m

$214

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Wed 9/24

2:59 pm-4:49 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Wed 10/1

6:00 am-7:49 am

Nonstop1h 49m

$224

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 11/27

8:00 am-2:46 pm

1 stop6h 46m

Knoxville McGhee Tyson

Tue 12/2

3:56 pm-8:39 pm

1 stop4h 43m

$230

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 10/18

8:19 am-10:13 am

Nonstop1h 54m

Knoxville McGhee Tyson

Sat 10/25

10:43 am-12:14 pm

Nonstop1h 31m

$234

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 10/28

9:00 am-1:42 pm

1 stop4h 42m

Knoxville McGhee Tyson

Fri 10/31

4:48 pm-9:43 pm

1 stop4h 55m

$234

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Fri 10/3

7:58 pm-9:41 pm

Nonstop1h 43m

Knoxville McGhee Tyson

Mon 10/6

8:37 pm-11:59 pm

1 stop3h 22m

$234

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 12/6

1:46 pm-6:59 pm

1 stop5h 13m

Knoxville McGhee Tyson

Sun 12/7

7:59 pm-11:39 pm

1 stop3h 40m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 18 results
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Best time to book a flight from Reagan-National to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Reagan-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Washington, D.C. Reagan-National Airport to Knoxville

How far ahead should I book a flight from Washington, D.C. Reagan-National Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Reagan-National to Knoxville. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Washington, D.C. Reagan-National Airport to Knoxville, you should look to book at least 44 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to Knoxville (average of $294). Flying from Washington, D.C. Reagan-National Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DCA to TYS?

Find hourly flight availability from Reagan-National to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

It’s typically best to fly out from Washington, D.C. Reagan-National Airport to Knoxville in the evening. Doing so could potentially save you 7% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Washington, D.C. Reagan-National Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Reagan-National to Knoxville. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Washington, D.C. Reagan-National Airport to Knoxville flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 16, 2025.
See what other customers who have flown with American Airlines from Washington, D.C. Reagan-National Airport to Knoxville have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Boarding

7.5

Comfort

7.2

Overall

7.2

Entertainment

6.9

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Boarding

7.5

Comfort

7.2

Overall

7.2

Entertainment

6.9

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Reagan-National to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Washington, D.C. Reagan-National?

    If you book a flight to Knoxville from Washington, D.C. Reagan-National, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 3 flights from Washington, D.C. Reagan-National to McGhee Tyson per day from 1 airline.

  • How long is the flight from Washington, D.C. Reagan-National Airport to Knoxville?

    American Airlines and Delta can get you from Washington, D.C. Reagan-National Airport to Knoxville in just under 1h 43m. Your travel time can differ by up to 4h 20m. Airlines will cover a distance of 436 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Washington, D.C. Reagan-National Airport to Knoxville round-trip?

    According to our current data, American Airlines ($199), offers the cheapest pricing from Washington, D.C. Reagan-National Airport to Knoxville. Users have found that American Airlines is 37% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Washington, D.C. Reagan-National Airport to Knoxville?

    Before booking your flight to Knoxville from Washington, D.C. Reagan-National Airport, check out the most reliable airlines to get you to your destination on time: Envoy Air (100%), Republic Airways (75%), American Airlines( 75%).

  • What are the cheapest flights from Washington, D.C. Reagan-National Airport to Knoxville?

    Looking at all options, your cheapest flight can be booked for $89. While the most popular route (Washington, D.C. Reagan-National - Knoxville McGhee Tyson) can be booked for $209 on average, our data indicates $269 when flying from Washington, D.C. Reagan-National Airport to Knoxville.

  • Can I find deals for flights from Reagan-National to Knoxville that include hotel bookings?

    Yes. In addition to deals on Reagan-National to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Reagan-National to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reagan-National to Knoxville.

  • Can I find deals for business class flights from Reagan-National to Knoxville?

    Yes. Cheapflights offers flight deals from Reagan-National to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to Knoxville (average of $294). Flying from Washington, D.C. Reagan-National Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top airline flying from Reagan-National to Knoxville

Discover the top airline that operate flights from Reagan-National to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$199Average$320FlexibilityNo cancel feeOn-time71%

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