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Knoxville

$96+ Cheap flights from North Carolina to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — TYS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from North Carolina to Knoxville

Keep the following information in mind while searching for North Carolina to Knoxville flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$194
(Kiwi.com)

One-way from

$96
(Kiwi.com)

Popular in

May

Cheapest in

August

Average price

$396

Good round-trip deal

$549 or less

Good one-way deal

$357 or less
Provider with most accurate pricing for Raleigh-Durham-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Knoxville McGhee Tyson flights.
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From North Carolina to Knoxville McGhee Tyson
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One-way flight from North Carolina to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from North Carolina to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from North Carolina to Knoxville McGhee Tyson.
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Find flight deals from North Carolina to Knoxville

Cheapest flights from North Carolina to Knoxville
Explore the most affordable flight options available from North Carolina to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:40 pmCLT - TYS
1 stop19h 17mMultiple Airlines
Fri 11/219:35 pmTYS - CLT
1 stop10h 41mMultiple Airlines
Deal found 10/30$194
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/101:19 pmORF - TYS
1 stop9h 55mMultiple Airlines
Wed 11/126:13 pmTYS - ORF
1 stop19h 02mMultiple Airlines
Deal found 10/29$201
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:11 pmORF - TYS
1 stop12h 22mMultiple Airlines
Mon 12/811:28 amTYS - ORF
2 stops28h 13mMultiple Airlines
Deal found 10/30$219
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:51 pmCLT - TYS
1 stop7h 02mMultiple Airlines
Wed 12/245:31 pmTYS - CLT
1 stop5h 58mMultiple Airlines
Deal found 10/30$228
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:28 amRDU - TYS
1 stop27h 33mMultiple Airlines
Mon 11/1710:15 amTYS - RDU
1 stop5h 07mMultiple Airlines
Deal found 10/29$228
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/13:51 pmCLT - TYS
1 stop6h 49mMultiple Airlines
Thu 12/412:43 pmTYS - CLT
1 stop11h 16mMultiple Airlines
Deal found 10/30$231
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:44 pmCLT - TYS
1 stop15h 50mMultiple Airlines
Wed 11/198:15 amTYS - CLT
1 stop11h 43mMultiple Airlines
Deal found 10/29$241
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:09 pmCLT - TYS
1 stop25h 10mMultiple Airlines
Thu 12/412:43 pmTYS - CLT
1 stop11h 16mMultiple Airlines
Deal found 10/29$248
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/209:06 amRDU - TYS
1 stop13h 20mMultiple Airlines
Fri 11/2110:32 amTYS - RDU
1 stop10h 04mMultiple Airlines
Deal found 10/29$250
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:06 amRDU - TYS
1 stop13h 36mMultiple Airlines
Sun 12/219:08 amTYS - RDU
1 stop7h 47mMultiple Airlines
Deal found 10/30$252
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:53 pmORF - TYS
1 stop14h 11mMultiple Airlines
Tue 11/1811:24 amTYS - ORF
1 stop7h 34mMultiple Airlines
Deal found 10/30$258
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:44 pmCLT - TYS
1 stop15h 20mMultiple Airlines
Tue 11/1811:24 amTYS - CLT
1 stop21h 38mMultiple Airlines
Deal found 10/30$263

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from North Carolina to Knoxville that are best for you.

Fly from

North Carolina

Fly to

Knoxville

Route

Depart

Return

Price

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Tue 11/18

5:40 pm-12:57 pm

1 stop19h 17m

Knoxville McGhee Tyson

Fri 11/21

9:35 pm-8:16 am

1 stop10h 41m

$194

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Mon 11/10

1:19 pm-11:14 pm

1 stop9h 55m

Knoxville McGhee Tyson

Wed 11/12

6:13 pm-1:15 pm

1 stop19h 02m

$201

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Thu 12/4

8:11 pm-8:33 am

1 stop12h 22m

Knoxville McGhee Tyson

Mon 12/8

11:28 am-3:41 pm

2 stops28h 13m

$219

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Fri 11/14

9:28 am-1:01 pm

1 stop27h 33m

Knoxville McGhee Tyson

Mon 11/17

10:15 am-3:22 pm

1 stop5h 07m

$228

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Thu 2/19

9:09 am-9:21 pm

1 stop12h 12m

Knoxville McGhee Tyson

Sun 2/22

11:50 am-7:24 pm

1 stop7h 34m

$241

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Thu 11/20

9:06 am-10:26 pm

1 stop13h 20m

Knoxville McGhee Tyson

Fri 11/21

10:32 am-8:36 pm

1 stop10h 04m

$250

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Mon 11/17

6:44 pm-10:34 am

1 stop15h 50m

Knoxville McGhee Tyson

Wed 11/19

8:15 am-6:54 pm

2 stops10h 39m

$252

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Sun 12/14

9:06 am-10:42 pm

1 stop13h 36m

Knoxville McGhee Tyson

Sun 12/21

9:08 am-4:55 pm

1 stop7h 47m

$252

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Thu 11/27

6:42 pm-7:19 pm

1 stop24h 37m

Knoxville McGhee Tyson

Thu 12/4

1:22 pm-7:12 pm

1 stop5h 50m

$257

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Thu 11/27

6:09 pm-7:19 pm

1 stop25h 10m

Knoxville McGhee Tyson

Thu 12/4

6:30 am-4:54 pm

1 stop10h 24m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 55 results
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Best time to book a flight from North Carolina to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Knoxville

What is the cheapest month to book a flight from North Carolina to Knoxville?

Currently, November is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $133). Flying from North Carolina to Knoxville in June is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to TYS?

Find hourly flight availability from North Carolina to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from North Carolina to Knoxville in the afternoon. Doing so could potentially save you 13% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from North Carolina to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Knoxville flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from North Carolina?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from North Carolina. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from North Carolina to Knoxville?

    For as low as $264, Delta can have you in Knoxville from North Carolina in 3h 21m. There are 360 mi between North Carolina and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from North Carolina to Knoxville?

    The most popular flight routes from North Carolina to Knoxville are Myrtle Beach Intl - Knoxville McGhee Tyson, Norfolk - Knoxville McGhee Tyson and Charlotte Douglas - Knoxville McGhee Tyson.

  • Can I find deals for flights from North Carolina to Knoxville that include hotel bookings?

    Yes. In addition to deals on North Carolina to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Knoxville.

  • Can I find deals for business class flights from North Carolina to Knoxville?

    Yes. Cheapflights offers flight deals from North Carolina to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $133). Flying from North Carolina to Knoxville in June is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Knoxville

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Top 3 airlines flying from North Carolina to Knoxville

Discover the top 3 airlines that operate flights from North Carolina to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$218Average$328FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$218Average$437FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$352FlexibilityNo cancel feeOn-timeN/A

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