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$83+ Cheap flights from North Carolina to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — TYS
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from North Carolina to Knoxville

Keep the following information in mind while searching for North Carolina to Knoxville flight deals. Data was last updated August 20, 2025.

Round-trip from

$204
(Mytrip)

One-way from

$83
(Mytrip)

Popular in

August

Cheapest in

November

Average price

$619

Good one-way deal

$320 or less
From North Carolina to Knoxville McGhee Tyson
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One-way flight from North Carolina to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a one-way flight from North Carolina to Knoxville McGhee Tyson.
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Find flight deals from North Carolina to Knoxville

Cheapest flights from North Carolina to Knoxville
Explore the most affordable flight options available from North Carolina to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Mytrip deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:15 amCLT - TYS
1 stop9h 21mMultiple Airlines
Sat 11/14:12 pmTYS - CLT
1 stop7h 25mMultiple Airlines
Deal found 8/20$204
This Mytrip deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/61:53 pmCLT - TYS
1 stop6h 48mMultiple Airlines
Thu 9/1112:08 pmTYS - CLT
1 stop10h 51mMultiple Airlines
Deal found 8/18$212
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/87:15 pmEWN - TYS
1 stop3h 48mAmerican Airlines
Mon 9/157:45 pmTYS - EWN
1 stop3h 24mAmerican Airlines
Deal found 8/18$214
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:15 amCLT - TYS
1 stop9h 21mMultiple Airlines
Fri 10/315:44 pmTYS - CLT
1 stop21h 12mMultiple Airlines
Deal found 8/20$215
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:03 pmRDU - TYS
1 stop3h 41mDelta
Fri 10/108:10 pmTYS - RDU
1 stop3h 54mDelta
Deal found 8/18$219
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:05 pmORF - TYS
1 stop5h 39mDelta
Sat 9/206:08 pmTYS - ORF
1 stop6h 17mDelta
Deal found 8/20$227
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:07 pmPGV - TYS
1 stop5h 56mAmerican Airlines
Mon 9/87:45 pmTYS - PGV
1 stop3h 41mAmerican Airlines
Deal found 8/20$229
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:32 pmILM - TYS
1 stop5h 35mAmerican Airlines
Mon 9/157:45 pmTYS - ILM
1 stop3h 23mAmerican Airlines
Deal found 8/20$229
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:45 pmORF - TYS
1 stop4h 01mDelta
Mon 10/208:10 pmTYS - ORF
1 stop4h 10mDelta
Deal found 8/18$229
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:36 pmMYR - TYS
1 stop5h 27mAmerican Airlines
Tue 9/237:45 pmTYS - MYR
1 stop3h 25mAmerican Airlines
Deal found 8/18$229
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/299:41 pmCLT - TYS
1 stop20h 27mMultiple Airlines
Sun 8/3111:00 amTYS - CLT
1 stop9h 46mMultiple Airlines
Deal found 8/19$234
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/410:59 amORF - TYS
1 stop5h 37mDelta
Mon 9/86:14 pmTYS - ORF
1 stop6h 10mDelta
Deal found 8/18$234

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from North Carolina to Knoxville that are best for you.

Fly from

North Carolina

Fly to

Knoxville

Route

Depart

Return

Price

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Wed 10/29

6:15 am-3:36 pm

1 stop9h 21m

Knoxville McGhee Tyson

Sat 11/1

4:12 pm-11:37 pm

1 stop7h 25m

$204

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Sat 9/6

1:53 pm-8:41 pm

1 stop6h 48m

Knoxville McGhee Tyson

Thu 9/11

12:08 pm-10:59 pm

1 stop10h 51m

$212

New BernKnoxville

EWN - TYS

EWNTYS

New Bern Coastal Carolina Rgnl

Mon 9/8

7:15 pm-11:03 pm

1 stop3h 48m

Knoxville McGhee Tyson

Mon 9/15

7:45 pm-11:09 pm

1 stop3h 24m

$214

New BernKnoxville

EWN - TYS

EWNTYS

New Bern Coastal Carolina Rgnl

Fri 9/26

6:00 am-9:56 am

1 stop3h 56m

Knoxville McGhee Tyson

Mon 9/29

7:45 pm-11:09 pm

1 stop3h 24m

$214

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Wed 10/29

6:15 am-3:36 pm

1 stop9h 21m

Knoxville McGhee Tyson

Fri 10/31

5:44 pm-2:56 pm

1 stop21h 12m

$215

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Fri 10/3

8:03 pm-11:44 pm

1 stop3h 41m

Knoxville McGhee Tyson

Fri 10/10

8:10 pm-12:04 am

1 stop3h 54m

$219

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Wed 9/17

6:08 am-11:11 am

1 stop5h 03m

Knoxville McGhee Tyson

Tue 9/23

4:13 pm-9:08 pm

1 stop4h 55m

$227

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Tue 9/16

3:00 pm-8:39 pm

1 stop5h 39m

Knoxville McGhee Tyson

Tue 9/23

4:13 pm-9:08 pm

1 stop4h 55m

$227

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Sat 9/13

6:05 pm-11:44 pm

1 stop5h 39m

Knoxville McGhee Tyson

Sat 9/20

6:08 pm-12:25 am

1 stop6h 17m

$227

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Fri 9/12

5:00 pm-10:36 pm

1 stop5h 36m

Knoxville McGhee Tyson

Mon 9/15

5:45 am-9:24 am

1 stop3h 39m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Knoxville

What is the cheapest month to book a flight from North Carolina to Knoxville?

Currently, January is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $295). Flying from North Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to TYS?

Find hourly flight availability from North Carolina to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

When flying from North Carolina to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from North Carolina?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from North Carolina. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from North Carolina to Knoxville?

    For as low as $219, American Airlines can have you in Knoxville from North Carolina in 3h 41m. There are 291 mi between North Carolina and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Knoxville one-way?

    The cheapest airlines for a one-way flight from North Carolina to Knoxville are Avelo Airlines ($83), Delta ($119), and United Airlines ($124).

  • What are the most popular routes from North Carolina to Knoxville?

    The most popular flight routes from North Carolina to Knoxville are Norfolk - Knoxville McGhee Tyson, Charlotte Douglas - Knoxville McGhee Tyson and Raleigh-Durham - Knoxville McGhee Tyson.

  • Can I find deals for flights from North Carolina to Knoxville that include hotel bookings?

    Yes. In addition to deals on North Carolina to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Knoxville.

  • Can I find deals for business class flights from North Carolina to Knoxville?

    Yes. Cheapflights offers flight deals from North Carolina to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $295). Flying from North Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for North Carolina to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from North Carolina to Knoxville

Discover the top 3 airlines that operate flights from North Carolina to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$218Average$328FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$218Average$430FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$318FlexibilityNo cancel feeOn-timeN/A

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