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Knoxville

$88+ Cheap flights from North Carolina to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — TYS
feb. 28 — mar. 71
sáb. 2/28
sáb. 3/7
1 adult, Economy
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Cheap flight deals from North Carolina to Knoxville

Cheapest flights from North Carolina to Knoxville
Explore the most affordable flight options available from North Carolina to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 29, 2026.

This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/225:50 am
ORF
-
TYS
1 stop4h 20m
Delta
sáb. 8/295:30 am
TYS
-
ORF
1 stop3h 34m
Delta
Deal found 1/28$225
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/21:56 pm
ORF
-
TYS
1 stop6h 44m
American Airlines
jue. 3/56:05 am
TYS
-
ORF
1 stop3h 59m
American Airlines
Deal found 1/28$235
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/246:00 am
ILM
-
TYS
1 stop5h 08m
Delta
mar. 3/35:35 am
TYS
-
ILM
1 stop3h 52m
Delta
Deal found 1/27$249
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/265:55 am
CLT
-
TYS
1 stop8h 40m
Multiple Airlines
vie. 2/279:36 pm
TYS
-
CLT
1 stop10h 50m
Multiple Airlines
Deal found 1/28$250
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/89:56 pm
RDU
-
TYS
1 stop19h 32m
Multiple Airlines
jue. 2/126:30 am
TYS
-
RDU
1 stop5h 46m
Multiple Airlines
Deal found 1/28$251
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/146:40 am
CLT
-
TYS
1 stop5h 20m
Southwest
mié. 4/155:50 pm
TYS
-
CLT
1 stop3h 50m
Southwest
Deal found 1/27$261
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/198:56 am
CLT
-
TYS
1 stop13h 30m
Multiple Airlines
dom. 3/225:24 pm
TYS
-
CLT
1 stop14h 57m
Multiple Airlines
Deal found 1/28$269
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/172:55 pm
ORF
-
TYS
1 stop5h 38m
Delta
lun. 8/247:20 pm
TYS
-
ORF
1 stop3h 37m
Delta
Deal found 1/28$269
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/37:43 pm
CLT
-
TYS
1 stop20h 14m
Multiple Airlines
mar. 2/101:00 pm
TYS
-
CLT
1 stop24h 51m
Multiple Airlines
Deal found 1/27$270
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/1010:57 am
ORF
-
TYS
1 stop5h 09m
Delta
vie. 3/136:38 pm
TYS
-
ORF
1 stop3h 42m
Delta
Deal found 1/28$271
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/56:08 pm
RDU
-
TYS
1 stop17h 52m
Multiple Airlines
dom. 3/86:30 am
TYS
-
RDU
1 stop8h 41m
Multiple Airlines
Deal found 1/27$272
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/256:54 pm
MYR
-
TYS
1 stop5h 03m
Delta
sáb. 3/285:40 am
TYS
-
MYR
1 stop3h 53m
Delta
Deal found 1/28$272

Find flight deals from North Carolina to Knoxville

Keep the following information in mind while searching for North Carolina to Knoxville flight deals. Data was last updated enero 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$235
(American Airlines)

One-way from

$88
(Trip.com)

Popular in

December

Cheapest in

August

Average price

$351

Good one-way deal

$320 or less
Provider with most accurate pricing for Raleigh-Durham-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Knoxville McGhee Tyson flights.
Search Deals
From North Carolina to Knoxville McGhee Tyson
Search Deals
One-way flight from North Carolina to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a one-way flight from North Carolina to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from North Carolina to Knoxville that are best for you.

Fly from

North Carolina

Fly to

Knoxville

Route

Depart

Return

Price

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

lun. 3/2

1:56 pm-8:40 pm

1 stop6h 44m

Knoxville McGhee Tyson

jue. 3/5

6:05 am-10:04 am

1 stop3h 59m

$235

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

mar. 2/24

6:00 am-11:08 am

1 stop5h 08m

Knoxville McGhee Tyson

mar. 3/3

5:35 am-9:27 am

1 stop3h 52m

$249

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

mié. 2/25

6:05 am-9:53 am

1 stop3h 48m

Knoxville McGhee Tyson

mié. 3/4

5:47 pm-10:56 pm

1 stop5h 09m

$249

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

jue. 2/26

5:55 am-2:35 pm

1 stop8h 40m

Knoxville McGhee Tyson

vie. 2/27

9:36 pm-8:26 am

1 stop10h 50m

$250

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

dom. 2/8

9:56 pm-5:28 pm

1 stop19h 32m

Knoxville McGhee Tyson

jue. 2/12

6:30 am-12:16 pm

1 stop5h 46m

$251

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

mar. 4/14

6:40 am-12:00 pm

1 stop5h 20m

Knoxville McGhee Tyson

mié. 4/15

5:50 pm-9:40 pm

1 stop3h 50m

$261

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

jue. 3/19

8:56 am-10:26 pm

1 stop13h 30m

Knoxville McGhee Tyson

dom. 3/22

5:24 pm-8:21 am

1 stop14h 57m

$269

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

mar. 3/10

10:57 am-4:06 pm

1 stop5h 09m

Knoxville McGhee Tyson

vie. 3/13

6:38 pm-10:20 pm

1 stop3h 42m

$271

Myrtle BeachKnoxville

MYR - TYS

MYRTYS

Myrtle Beach Intl

mié. 3/25

6:54 pm-11:57 pm

1 stop5h 03m

Knoxville McGhee Tyson

sáb. 3/28

5:40 am-9:33 am

1 stop3h 53m

$272

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

jue. 3/5

6:08 pm-12:00 pm

1 stop17h 52m

Knoxville McGhee Tyson

dom. 3/8

6:30 am-3:11 pm

1 stop8h 41m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

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Best time to book a flight from North Carolina to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Knoxville

What is the cheapest month to book a flight from North Carolina to Knoxville?

Currently, November is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $113). Flying from North Carolina to Knoxville in June is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to TYS?

Find hourly flight availability from North Carolina to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 29, 2026.

It’s typically best to fly out from North Carolina to Knoxville in the afternoon. Doing so could potentially save you 41% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from North Carolina?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from North Carolina. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from North Carolina to Knoxville?

    For as low as $249, American Airlines can have you in Knoxville from North Carolina in 5h 08m. There are 360 mi between North Carolina and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from North Carolina to Knoxville?

    The most popular flight routes from North Carolina to Knoxville are Norfolk - Knoxville McGhee Tyson, Charlotte Douglas - Knoxville McGhee Tyson and Wilmington New Hanover County - Knoxville McGhee Tyson.

  • Can I find deals for flights from North Carolina to Knoxville that include hotel bookings?

    Yes. In addition to deals on North Carolina to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Knoxville.

  • Can I find deals for business class flights from North Carolina to Knoxville?

    Yes. Cheapflights offers flight deals from North Carolina to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $113). Flying from North Carolina to Knoxville in June is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for North Carolina to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from North Carolina to Knoxville

Discover the top 2 airlines that operate flights from North Carolina to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$119Average$358FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$219Average$431FlexibilityNo cancel feeOn-time71%

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