$45+ Cheap flights from Mississippi to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — TYS
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to Knoxville
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Cheapest flights from Mississippi to KnoxvilleExplore the most affordable flight options available from Mississippi to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from Mississippi to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:20 pm -
Nonstop1h 12m
Fri 10/167:45 pm -
Nonstop1h 19m
Deal found 8/4![Allegiant Air logo]()
$79
This Booking.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:22 pm -
Nonstop1h 12m
Sun 10/46:11 pm -
Nonstop1h 19m
Deal found 8/4![Allegiant Air logo]()
$90
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:56 pm -
Nonstop1h 12m
Sun 11/85:37 pm -
Nonstop1h 19m
Deal found 8/6![Allegiant Air logo]()
$113
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:57 pm -
Nonstop1h 12m
Sun 9/275:38 pm -
Nonstop1h 19m
Deal found 8/6![Allegiant Air logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:58 pm -
1 stop20h 55m
Sun 10/46:11 pm -
Nonstop1h 19m
Deal found 8/4![Multiple Airlines logo]()
$191
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:47 am -
1 stop5h 48m
Fri 9/116:06 pm -
1 stop5h 46m
Deal found 8/7![American Airlines logo]()
$273
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:00 pm -
1 stop6h 45m
Sat 8/292:21 pm -
1 stop6h 17m
Deal found 8/4![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:02 pm -
1 stop4h 13m
Sat 9/197:50 am -
1 stop4h 56m
Deal found 8/5![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:53 pm -
1 stop3h 29m
Tue 11/311:50 am -
1 stop4h 14m
Deal found 8/4![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:30 pm -
1 stop4h 30m
Wed 9/308:05 am -
2 stops11h 00m
Deal found 8/7![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:05 am -
2 stops6h 15m
Sat 9/196:50 am -
1 stop8h 05m
Deal found 8/5![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
2 stops6h 15m
Fri 9/112:05 pm -
2 stops7h 10m
Deal found 8/7![Southwest logo]()
$316
Best flights from Mississippi to KnoxvilleDiscover carefully curated flight deals from Mississippi to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from Mississippi to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:00 pm -
1 stop5h 02m
Thu 11/54:11 pm -
1 stop3h 40m
Deal found 8/4![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:30 pm -
1 stop4h 30m
Wed 9/308:05 am -
2 stops11h 00m
Deal found 8/7![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:15 am -
1 stop5h 05m
Wed 8/267:15 am -
1 stop4h 58m
Deal found 8/5![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:45 pm -
1 stop4h 13m
Mon 9/77:25 pm -
1 stop4h 05m
Deal found 8/7![American Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:02 pm -
1 stop4h 20m
Mon 10/267:09 am -
1 stop4h 16m
Deal found 8/2![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:50 pm -
1 stop3h 55m
Sat 12/1212:35 pm -
1 stop6h 50m
Deal found 8/4![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:02 pm -
1 stop4h 13m
Sat 9/197:50 am -
1 stop4h 56m
Deal found 8/5![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:15 am -
1 stop5h 05m
Tue 8/257:15 am -
1 stop4h 58m
Deal found 8/4![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:05 am -
2 stops6h 15m
Sat 9/196:50 am -
1 stop8h 05m
Deal found 8/5![Southwest logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:00 am -
1 stop5h 20m
Thu 9/103:40 pm -
1 stop5h 40m
Deal found 8/3![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:15 am -
1 stop2h 50m
Thu 9/242:05 pm -
2 stops7h 30m
Deal found 8/5![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:50 am -
2 stops8h 31m
Tue 11/35:32 pm -
1 stop6h 31m
Deal found 8/5![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:35 am -
1 stop4h 43m
Thu 9/247:25 pm -
1 stop4h 56m
Deal found 8/3![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:45 am -
2 stops6h 40m
Thu 10/11:50 pm -
2 stops9h 35m
Deal found 8/3![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:52 pm -
1 stop5h 30m
Sun 11/157:21 pm -
1 stop3h 41m
Deal found 8/3![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:10 pm -
1 stop4h 30m
Tue 10/65:15 pm -
1 stop5h 20m
Deal found 8/2![Southwest logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:42 pm -
1 stop6h 24m
Sun 9/208:13 pm -
1 stop4h 44m
Deal found 8/7![American Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:20 am -
1 stop7h 57m
Wed 8/263:40 pm -
1 stop5h 25m
Deal found 8/6![United Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:15 am -
1 stop2h 45m
Sun 11/87:25 pm -
1 stop5h 15m
Deal found 8/7![Southwest logo]()
$338
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
2 stops6h 15m
Fri 9/112:05 pm -
2 stops7h 10m
Deal found 8/6![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:59 pm -
1 stop4h 56m
Mon 10/57:25 pm -
1 stop3h 43m
Deal found 8/4![Delta logo]()
$417
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:00 pm -
1 stop5h 15m
Sat 9/197:15 am -
1 stop4h 58m
Deal found 8/3![United Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:27 pm -
2 stops7h 31m
Thu 9/36:03 am -
1 stop5h 39m
Deal found 8/6![American Airlines logo]()
$547
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:40 pm -
2 stops9h 00m
Sun 11/17:05 am -
2 stops9h 15m
Deal found 8/2![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:59 pm -
1 stop4h 56m
Fri 9/185:40 am -
1 stop4h 36m
Deal found 8/2![Delta logo]()
$443
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:20 am -
2 stops7h 30m
Sun 11/157:05 am -
1 stop3h 10m
Deal found 8/5![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:15 am -
1 stop5h 05m
Mon 9/77:15 am -
1 stop4h 58m
Deal found 8/5![United Airlines logo]()
$526
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:59 pm -
2 stops26h 54m
Mon 8/313:40 pm -
1 stop4h 58m
Deal found 8/3![United Airlines logo]()
$553
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am -
2 stops9h 30m
Mon 10/2612:50 pm -
2 stops8h 00m
Deal found 8/2![Southwest logo]()
$433
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:10 pm -
1 stop4h 35m
Mon 9/77:15 am -
1 stop4h 58m
Deal found 8/3![United Airlines logo]()
$590
Last-minute flights from Mississippi to KnoxvilleDiscover last-minute flight deals from Mississippi to Knoxville. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Knoxville. Data last updated August 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:00 pm -
1 stop6h 45m
Sat 8/292:21 pm -
1 stop6h 17m
Deal found 8/4![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:47 am -
1 stop5h 48m
Fri 9/116:06 pm -
1 stop5h 46m
Deal found 8/7![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:37 am -
1 stop5h 58m
Sat 9/128:18 am -
1 stop3h 48m
Deal found 8/6![American Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
2 stops6h 15m
Fri 9/112:05 pm -
2 stops7h 10m
Deal found 8/7![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:15 am -
2 stops6h 05m
Fri 9/115:45 pm -
1 stop5h 15m
Deal found 8/3![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:02 pm -
1 stop4h 13m
Sat 9/197:50 am -
1 stop4h 56m
Deal found 8/5![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:05 am -
2 stops6h 15m
Sat 9/196:50 am -
1 stop8h 05m
Deal found 8/5![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:35 am -
1 stop4h 43m
Thu 9/247:25 pm -
1 stop4h 56m
Deal found 8/4![Delta logo]()
$323
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:57 pm -
Nonstop1h 12m
Sun 9/275:38 pm -
Nonstop1h 19m
Deal found 8/6![Allegiant Air logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:58 pm -
1 stop21h 07m
Sun 9/275:38 pm -
Nonstop1h 19m
Deal found 8/4![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:58 pm -
1 stop18h 21m
Thu 10/18:23 pm -
1 stop23h 55m
Deal found 8/3![Multiple Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:30 pm -
1 stop4h 30m
Wed 9/308:05 am -
2 stops11h 00m
Deal found 8/7![Southwest logo]()
$304
One-way flights from Mississippi to KnoxvilleSearch for one-way flight options from Mississippi to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from Mississippi to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This Mytrip deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:22 pm -
Nonstop1h 12m
Deal found 8/5![Allegiant Air logo]()
$45
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:47 pm -
Nonstop1h 12m
Deal found 8/2![Allegiant Air logo]()
$46
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:57 pm -
Nonstop1h 12m
Deal found 8/2![Allegiant Air logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:58 pm -
1 stop21h 07m
Deal found 8/7![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:25 pm -
1 stop22h 40m
Deal found 8/7![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:39 pm -
1 stop13h 26m
Deal found 8/5![Allegiant Air logo]()
$134
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:18 am -
1 stop6h 09m
Deal found 8/6![American Airlines logo]()
$138
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:35 am -
2 stops8h 05m
Deal found 8/7![Southwest logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:35 pm -
2 stops15h 06m
Deal found 8/7![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:58 pm -
1 stop21h 07m
Deal found 8/7![Multiple Airlines logo]()
$150
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:00 pm -
1 stop5h 39m
Deal found 8/4![Delta logo]()
$151
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:15 am -
1 stop6h 42m
Deal found 8/4![American Airlines logo]()
$155
Find flight deals from Mississippi to Knoxville
Keep the following information in mind while searching for Mississippi to Knoxville flight deals. Data was last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $79 (Kiwi.com) |
One-way from | $45 (Mytrip) |
Popular in | November |
Cheapest in | December |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Mississippi to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonKnoxville
JAN Jackson-Evers Intl - TYS Knoxville McGhee Tyson
JANTYS
Jackson-Evers Intl
Wed 11/4
4:00 pm-10:02 pm
1 stop5h 02m
Knoxville McGhee Tyson
Thu 11/5
4:11 pm-6:51 pm
1 stop3h 40m
$299
JacksonKnoxville
JAN Jackson-Evers Intl - TYS Knoxville McGhee Tyson
JANTYS
Jackson-Evers Intl
Sat 10/24
5:02 pm-10:22 pm
1 stop4h 20m
Knoxville McGhee Tyson
Mon 10/26
7:09 am-10:25 am
1 stop4h 16m
$299
JacksonKnoxville
JAN Jackson-Evers Intl - TYS Knoxville McGhee Tyson
JANTYS
Jackson-Evers Intl
Tue 9/15
3:02 pm-8:15 pm
1 stop4h 13m
Knoxville McGhee Tyson
Sat 9/19
7:50 am-11:46 am
1 stop4h 56m
$299
JacksonKnoxville
JAN Jackson-Evers Intl - TYS Knoxville McGhee Tyson
JANTYS
Jackson-Evers Intl
Tue 9/29
1:30 pm-7:00 pm
1 stop4h 30m
Knoxville McGhee Tyson
Wed 9/30
8:05 am-6:05 pm
2 stops11h 00m
$304
MemphisKnoxville
MEM Memphis - TYS Knoxville McGhee Tyson
MEMTYS
Memphis
Thu 12/10
2:50 pm-7:45 pm
1 stop3h 55m
Knoxville McGhee Tyson
Sat 12/12
12:35 pm-6:25 pm
1 stop6h 50m
$309
JacksonKnoxville
JAN Jackson-Evers Intl - TYS Knoxville McGhee Tyson
JANTYS
Jackson-Evers Intl
Tue 9/15
7:05 am-2:20 pm
2 stops6h 15m
Knoxville McGhee Tyson
Sat 9/19
6:50 am-1:55 pm
1 stop8h 05m
$310
MemphisKnoxville
MEM Memphis - TYS Knoxville McGhee Tyson
MEMTYS
Memphis
Tue 9/22
8:15 am-12:05 pm
1 stop2h 50m
Knoxville McGhee Tyson
Thu 9/24
2:05 pm-8:35 pm
2 stops7h 30m
$314
MemphisKnoxville
MEM Memphis - TYS Knoxville McGhee Tyson
MEMTYS
Memphis
Mon 9/28
5:45 am-1:25 pm
2 stops6h 40m
Knoxville McGhee Tyson
Thu 10/1
1:50 pm-10:25 pm
2 stops9h 35m
$319
JacksonKnoxville
JAN Jackson-Evers Intl - TYS Knoxville McGhee Tyson
JANTYS
Jackson-Evers Intl
Sun 9/20
5:35 am-11:18 am
1 stop4h 43m
Knoxville McGhee Tyson
Thu 9/24
7:25 pm-11:21 pm
1 stop4h 56m
$323
MemphisKnoxville
MEM Memphis - TYS Knoxville McGhee Tyson
MEMTYS
Memphis
Fri 10/2
5:10 pm-10:40 pm
1 stop4h 30m
Knoxville McGhee Tyson
Tue 10/6
5:15 pm-9:35 pm
1 stop5h 20m
$324
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Mississippi with our price prediction graph.
MEM-TYS
GPT-TYS
JAN-TYS
BTR-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Knoxville
USMS-TYS
MEM-TYS
GPT-TYS
JAN-TYS
BTR-TYS
What is the cheapest month to book a flight from Mississippi to Knoxville?
Currently, September is the cheapest month in which you can book a flight from Mississippi to Knoxville (average of $335). Flying from Mississippi to Knoxville in March is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to Knoxville
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Complete your trip
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Search flights from Mississippi to Knoxville by cabin class
Find flights from Mississippi to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
Mississippi and Knoxville flights
Browse other Mississippi and Knoxville flight options. Last updated on August 7, 2026.
Popular flight searches
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Mississippi to Knoxville flights
Consider these flights traveling from Mississippi to Knoxville.
Top 2 airlines flying from Mississippi to Knoxville
Discover the top 2 airlines that operate flights from Mississippi to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$412 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$234 | Average$441 | FlexibilityNo cancel fee | On-timeN/A |