HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mississippi

$84+ Cheap flights from Knoxville (TYS) to Mississippi

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Aug 9 — Aug 161
Sun 8/9
Sun 8/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Mississippi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Mississippi

Cheapest flights from Knoxville to Mississippi
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:45 pm
TYS
-
MEM
Nonstop1h 19m
Allegiant Air
Sun 10/183:21 pm
MEM
-
TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/7$84
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:13 pm
TYS
-
MEM
Nonstop1h 19m
Allegiant Air
Sun 10/183:21 pm
MEM
-
TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/6$85
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:48 pm
TYS
-
MEM
Nonstop1h 19m
Allegiant Air
Sun 9/276:47 pm
MEM
-
TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/7$95
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:43 am
TYS
-
MEM
1 stop5h 22m
Allegiant Air
Sun 10/183:21 pm
MEM
-
TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/7$166
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:25 pm
TYS
-
MEM
2 stops25h 53m
Multiple Airlines
Sun 10/183:21 pm
MEM
-
TYS
Nonstop1h 12m
Multiple Airlines
Deal found 7/7$202
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:26 am
TYS
-
MEM
1 stop23h 48m
Allegiant Air
Fri 8/145:04 pm
MEM
-
TYS
1 stop22h 09m
Allegiant Air
Deal found 7/9$215
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/64:22 pm
TYS
-
MEM
1 stop4h 23m
American Airlines
Thu 8/138:15 am
MEM
-
TYS
1 stop4h 16m
American Airlines
Deal found 7/9$233
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:05 am
TYS
-
JAN
2 stops11h 00m
Southwest
Tue 8/117:05 am
JAN
-
TYS
2 stops6h 15m
Southwest
Deal found 7/7$233
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:42 pm
TYS
-
MEM
1 stop26h 08m
Allegiant Air
Fri 8/75:04 pm
MEM
-
TYS
1 stop16h 22m
Allegiant Air
Deal found 7/7$234
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:00 pm
TYS
-
BTR
1 stop4h 46m
Delta
Sun 8/97:13 pm
BTR
-
TYS
1 stop3h 39m
Delta
Deal found 7/6$310
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:28 am
TYS
-
GPT
1 stop3h 35m
Delta
Tue 8/116:30 am
GPT
-
TYS
1 stop3h 41m
Delta
Deal found 7/7$311
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:12 pm
TYS
-
GPT
1 stop5h 09m
Delta
Thu 8/1310:01 am
GPT
-
TYS
1 stop6h 18m
Delta
Deal found 7/9$314

Find flight deals from Knoxville to Mississippi

Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated July 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$84
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$477
Provider with most accurate pricing for Knoxville McGhee Tyson-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Jackson-Evers Intl flights.
Search Deals
From Knoxville McGhee Tyson to Mississippi
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Fri 10/16

7:45 pm-8:04 pm

Nonstop1h 19m

Memphis

Sun 10/18

3:21 pm-5:33 pm

Nonstop1h 12m

$84

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Wed 8/5

8:05 am-6:05 pm

2 stops11h 00m

Jackson-Evers Intl

Tue 8/11

7:05 am-2:20 pm

2 stops6h 15m

$233

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Tue 9/8

5:30 pm-9:45 pm

1 stop5h 15m

Memphis

Thu 9/10

8:15 am-7:55 pm

2 stops10h 40m

$299

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Sat 10/24

8:10 am-2:25 pm

2 stops7h 15m

Memphis

Mon 10/26

12:40 pm-10:40 pm

2 stops9h 00m

$306

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sat 8/8

6:00 am-9:39 am

1 stop4h 39m

Baton Rouge Ryan

Sun 8/9

7:13 pm-11:52 pm

1 stop3h 39m

$310

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sat 8/8

6:00 am-9:39 am

1 stop4h 39m

Baton Rouge Ryan

Mon 8/10

7:13 pm-11:52 pm

1 stop3h 39m

$310

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

Tue 8/4

10:28 am-1:03 pm

1 stop3h 35m

Gulfport Biloxi Regional

Tue 8/11

6:30 am-11:11 am

1 stop3h 41m

$311

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Mon 8/10

7:10 am-9:00 am

1 stop2h 50m

Memphis

Mon 8/10

2:55 pm-6:35 pm

1 stop2h 40m

$316

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Wed 7/29

12:10 pm-5:34 pm

1 stop6h 24m

Baton Rouge Ryan

Sat 8/1

4:09 pm-11:12 pm

1 stop6h 03m

$322

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

Fri 12/18

5:30 am-9:39 am

1 stop5h 09m

Gulfport Biloxi Regional

Mon 12/28

6:00 am-11:06 am

1 stop4h 06m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/8

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Knoxville to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mississippi

What is the cheapest month to book a flight from Knoxville to Mississippi?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 10, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,456 reviews

Overall

7.8

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,456 reviews
Delta
7.8
Good
8,456 reviews

Overall

7.8

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,799 reviews
Delta
7.8
Good
8,456 reviews

Overall

7.8

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mississippi?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Mississippi. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Mississippi?

    For as low as $84, Allegiant Air can have you in Mississippi from Knoxville in 1h 19m. The distance between Knoxville and Mississippi is about 341 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Mississippi?

    While some choose either Knoxville McGhee Tyson - Baton Rouge Ryan or Knoxville McGhee Tyson - Mobile, Knoxville McGhee Tyson - Memphis is the most popular route from Knoxville to Mississippi.

  • Can I find deals for flights from Knoxville to Mississippi that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mississippi.

  • Can I find deals for business class flights from Knoxville to Mississippi?

    Yes. Cheapflights offers flight deals from Knoxville to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mississippi?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Seattle flights
Nashville to Newark flights
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to Boston flights
Nashville to Las Vegas flights
Nashville to Orlando flights
Memphis to Hobby flights
Nashville to Los Angeles flights
Memphis to Newark flights
Nashville to O'Hare Intl flights
Nashville to Denver flights
Nashville to Miami flights
Memphis to Orlando flights
Memphis to Las Vegas flights
Memphis to George Bush Intcntl flights
Memphis to LaGuardia flights
Nashville to Dallas/Fort Worth flights
Nashville to Hobby flights
Nashville to George Bush Intcntl flights
Memphis to Miami flights
Memphis to Dallas/Fort Worth flights
Memphis to Los Angeles flights
Memphis to O'Hare Intl flights
Knoxville to LaGuardia flights
Nashville to San Francisco flights
Nashville to Baltimore flights
Nashville to Reagan-National flights
Memphis to Denver flights
Nashville to Philadelphia flights
Nashville to Fort Lauderdale flights
Nashville to Sky Harbor Intl flights
Nashville to Salt Lake City flights
Chattanooga to Orlando flights
Chattanooga to John F Kennedy Intl flights
Chattanooga to LaGuardia flights
Chattanooga to Newark flights
Memphis to John F Kennedy Intl flights
Chattanooga to O'Hare Intl flights
Knoxville to John F Kennedy Intl flights
Nashville to Dulles Intl flights
Chattanooga to Las Vegas flights
Knoxville to Seattle flights
Nashville to Midway flights
Nashville to Tampa flights
Nashville to San Diego flights
Knoxville to Orlando flights
Memphis to Fort Lauderdale flights
Nashville to Detroit flights

Top 2 airlines flying from Knoxville to Mississippi

Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$450FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$278Average$416FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.