$104+ Cheap flights from Knoxville (TYS) to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Mai 23 — Mai 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Mississippi
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MississippiExplore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/287:27 pm
TYS
- MEM
1 stop23h 56m
Multiple Airlines
Mo 6/15:04 pm
MEM
- TYS
1 stop22h 11m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/81:15 pm
TYS
- MEM
1 stop28h 17m
Multiple Airlines
Mo 5/118:05 am
MEM
- TYS
1 stop24h 35m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/309:25 pm
TYS
- MEM
1 stop21h 24m
Allegiant Air
So 5/37:55 pm
MEM
- TYS
1 stop21h 20m
Allegiant Air
Deal found 4/18![Allegiant Air logo]()
$229
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/205:40 am
TYS
- JAN
1 stop4h 14m
Delta
Mi 5/279:34 am
JAN
- TYS
1 stop3h 59m
Delta
Deal found 4/21![Delta logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/141:14 pm
TYS
- MEM
1 stop5h 56m
Multiple Airlines
So 5/175:37 pm
MEM
- TYS
1 stop27h 47m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/265:40 am
TYS
- MEM
1 stop5h 55m
Delta
Mi 5/278:30 am
MEM
- TYS
1 stop3h 40m
Delta
Deal found 4/21![Delta logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/141:14 pm
TYS
- MEM
1 stop5h 56m
Multiple Airlines
Fr 5/155:37 pm
MEM
- TYS
1 stop23h 26m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:10 pm
TYS
- MEM
1 stop15h 05m
Multiple Airlines
Fr 5/87:03 pm
MEM
- TYS
1 stop17h 06m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:10 pm
TYS
- MEM
1 stop15h 05m
Allegiant Air
Mo 5/118:05 am
MEM
- TYS
1 stop24h 35m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$246
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/247:10 am
TYS
- JAN
2 stops5h 50m
Southwest
Di 8/251:30 pm
JAN
- TYS
1 stop4h 25m
Southwest
Deal found 4/20![Southwest logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:10 pm
TYS
- MEM
1 stop15h 05m
Allegiant Air
Do 5/147:00 pm
MEM
- TYS
1 stop25h 48m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/17:30 am
TYS
- MEM
1 stop11h 19m
Allegiant Air
So 5/37:55 pm
MEM
- TYS
1 stop24h 53m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$254
Best flights from Knoxville to MississippiDiscover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/81:15 pm
TYS
- MEM
1 stop28h 17m
Multiple Airlines
Mo 5/118:05 am
MEM
- TYS
1 stop24h 35m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$225
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/247:10 am
TYS
- JAN
2 stops5h 50m
Southwest
Di 8/251:30 pm
JAN
- TYS
1 stop4h 25m
Southwest
Deal found 4/20![Southwest logo]()
$249
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/145:00 am
TYS
- MEM
1 stop4h 18m
American Airlines
Di 5/195:38 pm
MEM
- TYS
1 stop4h 18m
American Airlines
Deal found 4/21![American Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/25:40 am
TYS
- JAN
1 stop4h 14m
Delta
Fr 6/129:39 am
JAN
- TYS
1 stop4h 10m
Delta
Deal found 4/22![Delta logo]()
$347
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/63:30 pm
TYS
- GPT
1 stop5h 23m
United Airlines
So 5/104:55 pm
GPT
- TYS
1 stop5h 49m
United Airlines
Deal found 4/21![United Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/79:40 pm
TYS
- MEM
2 stops19h 52m
Multiple Airlines
Mo 5/118:05 am
MEM
- TYS
1 stop24h 35m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/305:40 am
TYS
- GPT
1 stop4h 41m
Delta
Di 7/76:00 pm
GPT
- TYS
1 stop4h 52m
Delta
Deal found 4/21![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/25:50 pm
TYS
- MEM
1 stop4h 55m
Southwest
Di 6/94:15 pm
MEM
- TYS
1 stop3h 05m
Southwest
Deal found 4/18![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/35:40 am
TYS
- GPT
1 stop4h 41m
Delta
Di 7/76:00 pm
GPT
- TYS
1 stop4h 52m
Delta
Deal found 4/21![Delta logo]()
$352
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 8/183:25 pm
TYS
- AEX
1 stop5h 13m
United Airlines
Sa 8/224:05 pm
AEX
- TYS
1 stop4h 25m
United Airlines
Deal found 4/17![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/2012:50 pm
TYS
- MEM
2 stops9h 55m
Southwest
Mi 5/279:45 am
MEM
- TYS
2 stops8h 55m
Southwest
Deal found 4/22![Southwest logo]()
$387
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/35:40 am
TYS
- MOB
1 stop3h 55m
Delta
Di 7/74:26 pm
MOB
- TYS
1 stop4h 32m
Delta
Deal found 4/21![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/286:30 am
TYS
- MEM
1 stop5h 37m
United Airlines
Mo 6/16:30 pm
MEM
- TYS
1 stop5h 00m
United Airlines
Deal found 4/21![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/215:40 am
TYS
- MOB
1 stop3h 45m
Delta
So 5/245:10 pm
MOB
- TYS
1 stop5h 46m
Delta
Deal found 4/20![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/236:07 pm
TYS
- MOB
1 stop4h 29m
American Airlines
Di 5/2612:42 pm
MOB
- TYS
2 stops10h 17m
American Airlines
Deal found 4/21![American Airlines logo]()
$508
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 5/46:35 am
TYS
- MEM
1 stop3h 05m
Southwest
Di 5/59:45 am
MEM
- TYS
2 stops8h 55m
Southwest
Deal found 4/20![Southwest logo]()
$442
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 7/97:43 pm
TYS
- MOB
1 stop4h 42m
Delta
So 7/126:55 pm
MOB
- TYS
1 stop3h 57m
Delta
Deal found 4/22![Delta logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/306:00 am
TYS
- GPT
2 stops13h 40m
Multiple Airlines
So 5/37:20 pm
GPT
- TYS
1 stop21h 10m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$493
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 8/77:15 am
TYS
- JAN
1 stop5h 09m
United Airlines
Di 8/1112:00 pm
JAN
- TYS
1 stop5h 05m
United Airlines
Deal found 4/20![United Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/3011:40 am
TYS
- GPT
1 stop6h 53m
American Airlines
So 5/36:00 am
GPT
- TYS
1 stop4h 15m
American Airlines
Deal found 4/20![American Airlines logo]()
$515
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 6/56:40 am
TYS
- MEM
2 stops8h 10m
Southwest
So 6/76:15 am
MEM
- TYS
2 stops9h 55m
Southwest
Deal found 4/19![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 8/47:15 am
TYS
- BTR
1 stop5h 05m
United Airlines
Sa 8/84:09 pm
BTR
- TYS
1 stop6h 03m
United Airlines
Deal found 4/18![United Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 6/15:59 pm
TYS
- BTR
1 stop5h 01m
Delta
Mo 6/87:06 pm
BTR
- TYS
1 stop3h 48m
Delta
Deal found 4/22![Delta logo]()
$388
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 6/55:40 am
TYS
- MOB
1 stop3h 45m
Delta
So 6/76:59 pm
MOB
- TYS
1 stop3h 55m
Delta
Deal found 4/19![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/146:35 am
TYS
- MEM
2 stops9h 55m
Southwest
So 5/175:40 am
MEM
- TYS
2 stops7h 25m
Southwest
Deal found 4/21![Southwest logo]()
$493
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 5/187:33 pm
TYS
- MOB
1 stop4h 55m
Delta
Mo 5/257:01 pm
MOB
- TYS
1 stop3h 55m
Delta
Deal found 4/20![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/68:45 am
TYS
- JAN
1 stop4h 23m
Delta
So 5/107:30 am
JAN
- TYS
1 stop4h 40m
Delta
Deal found 4/21![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:40 am
TYS
- GPT
1 stop4h 41m
Delta
So 5/106:32 am
GPT
- TYS
1 stop3h 37m
Delta
Deal found 4/21![Delta logo]()
$447
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/203:30 pm
TYS
- GPT
1 stop7h 17m
United Airlines
Mi 5/272:00 pm
GPT
- TYS
2 stops32h 54m
United Airlines
Deal found 4/22![United Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 8/133:25 pm
TYS
- MOB
1 stop27h 52m
United Airlines
Di 8/189:30 am
MOB
- TYS
1 stop11h 00m
United Airlines
Deal found 4/20![United Airlines logo]()
$722
Last-minute flights from Knoxville to MississippiDiscover last-minute flight deals from Knoxville to Mississippi. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mississippi. Data last updated April 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/309:25 pm
TYS
- MEM
1 stop21h 24m
Allegiant Air
So 5/37:55 pm
MEM
- TYS
1 stop21h 20m
Allegiant Air
Deal found 4/18![Allegiant Air logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/17:30 am
TYS
- MEM
1 stop11h 19m
Allegiant Air
So 5/37:55 pm
MEM
- TYS
1 stop24h 53m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/64:25 pm
TYS
- GPT
2 stops27h 45m
Multiple Airlines
So 5/107:50 pm
GPT
- TYS
1 stop20h 40m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:10 pm
TYS
- MEM
1 stop15h 05m
Allegiant Air
Mo 5/118:05 am
MEM
- TYS
1 stop24h 35m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:10 pm
TYS
- MEM
1 stop15h 05m
Multiple Airlines
Fr 5/87:03 pm
MEM
- TYS
1 stop17h 06m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/75:10 pm
TYS
- MEM
1 stop15h 05m
Allegiant Air
Do 5/147:00 pm
MEM
- TYS
1 stop25h 48m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/81:15 pm
TYS
- MEM
1 stop28h 17m
Multiple Airlines
Mo 5/118:05 am
MEM
- TYS
1 stop24h 35m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/141:14 pm
TYS
- MEM
1 stop5h 56m
Multiple Airlines
So 5/175:37 pm
MEM
- TYS
1 stop27h 47m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/141:14 pm
TYS
- MEM
1 stop5h 56m
Multiple Airlines
Fr 5/155:37 pm
MEM
- TYS
1 stop23h 26m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$244
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/205:40 am
TYS
- JAN
1 stop4h 14m
Delta
Mi 5/279:34 am
JAN
- TYS
1 stop3h 59m
Delta
Deal found 4/21![Delta logo]()
$233
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/265:40 am
TYS
- MEM
1 stop5h 55m
Delta
Mi 5/278:30 am
MEM
- TYS
1 stop3h 40m
Delta
Deal found 4/21![Delta logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/287:27 pm
TYS
- MEM
1 stop23h 56m
Multiple Airlines
Mo 6/15:04 pm
MEM
- TYS
1 stop22h 11m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$208
One-way flights from Knoxville to MississippiSearch for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/242:19 pm
TYS
- MEM
1 stop18h 10m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 6/259:38 pm
TYS
- MEM
1 stop10h 45m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 6/72:05 pm
TYS
- MEM
1 stop18h 41m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/151:15 pm
TYS
- MEM
1 stop28h 17m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$135
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/27:05 am
TYS
- MEM
1 stop3h 00m
Southwest
Deal found 4/17![Southwest logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/79:40 pm
TYS
- MEM
1 stop21h 09m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/2210:03 pm
TYS
- MEM
1 stop19h 29m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 5/249:19 pm
TYS
- MEM
1 stop11h 15m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$172
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/247:59 pm
TYS
- MEM
1 stop4h 26m
American Airlines
Deal found 4/22![American Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/64:25 pm
TYS
- MEM
2 stops39h 50m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/2412:45 pm
TYS
- MEM
2 stops11h 00m
Southwest
Deal found 4/21![Southwest logo]()
$183
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/225:40 am
TYS
- MOB
1 stop3h 45m
Delta
Deal found 4/21![Delta logo]()
$190
Find flight deals from Knoxville to Mississippi
Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $208 (Kiwi.com) |
One-way from | $104 (Kiwi.com) |
Popular in | September |
Cheapest in | June |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Fr 5/8
1:15 pm-4:32 pm
1 stop28h 17m
Memphis
Mo 5/11
8:05 am-9:40 am
1 stop24h 35m
$225
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Mo 8/24
7:10 am-12:00 pm
2 stops5h 50m
Jackson-Evers Intl
Di 8/25
1:30 pm-6:55 pm
1 stop4h 25m
$249
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Do 5/14
5:00 am-8:18 am
1 stop4h 18m
Memphis
Di 5/19
5:38 pm-10:56 pm
1 stop4h 18m
$283
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Do 5/7
9:40 pm-4:32 pm
2 stops19h 52m
Memphis
Mo 5/11
8:05 am-9:40 am
1 stop24h 35m
$319
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Di 6/2
5:40 am-8:54 am
1 stop4h 14m
Jackson-Evers Intl
Fr 6/12
9:39 am-2:49 pm
1 stop4h 10m
$347
KnoxvilleGulfport
TYS - GPT
TYSGPT
Knoxville McGhee Tyson
Di 6/30
5:40 am-9:21 am
1 stop4h 41m
Gulfport Biloxi Regional
Di 7/7
6:00 pm-11:52 pm
1 stop4h 52m
$347
KnoxvilleGulfport
TYS - GPT
TYSGPT
Knoxville McGhee Tyson
Fr 7/3
5:40 am-9:21 am
1 stop4h 41m
Gulfport Biloxi Regional
Di 7/7
6:00 pm-11:52 pm
1 stop4h 52m
$352
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Di 6/2
5:50 pm-9:45 pm
1 stop4h 55m
Memphis
Di 6/9
4:15 pm-8:20 pm
1 stop3h 05m
$355
KnoxvilleMobile
TYS - MOB
TYSMOB
Knoxville McGhee Tyson
Fr 7/3
5:40 am-8:35 am
1 stop3h 55m
Mobile
Di 7/7
4:26 pm-9:58 pm
1 stop4h 32m
$357
KnoxvilleMobile
TYS - MOB
TYSMOB
Knoxville McGhee Tyson
Do 5/21
5:40 am-8:25 am
1 stop3h 45m
Mobile
So 5/24
5:10 pm-11:56 pm
1 stop5h 46m
$367
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
TYS-MEM
TYS-JAN
TYS-GPT
TYS-AEX
TYS-MOB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mississippi
TYS-USMS
TYS-MEM
TYS-JAN
TYS-GPT
TYS-AEX
What is the cheapest month to book a flight from Knoxville to Mississippi?
Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated April 23, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Knoxville to Mississippi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Mississippi by cabin class
Find flights from Knoxville to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Mississippi flights
Browse other Knoxville and Mississippi flight options. Last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Mississippi flights
Consider these flights traveling from Knoxville to Mississippi.
Top 2 airlines flying from Knoxville to Mississippi
Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$209 | Average$442 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$233 | Average$366 | FlexibilityNo cancel fee | On-time71% |