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$323+ Cheap flights from Mexico to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — TYS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Mexico to Knoxville

Keep the following information in mind while searching for Mexico to Knoxville flight deals. Data was last updated July 31, 2025.

Round-trip from

$535
(Delta)

One-way from

$323
(Kiwi.com)

Popular in

May

Cheapest in

March

Average price

$651
From Mexico to Knoxville McGhee Tyson
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One-way flight from Mexico to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 3% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Mexico to Knoxville

Cheapest flights from Mexico to Knoxville
Explore the most affordable flight options available from Mexico to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/129:04 amSLP - TYS
1 stop6h 15mDelta
Thu 12/115:30 amTYS - SLP
1 stop13h 49mDelta
Deal found 7/29$535
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/162:45 pmSLP - TYS
2 stops27h 17mMultiple Airlines
Thu 12/116:00 amTYS - SLP
3 stops32h 29mMultiple Airlines
Deal found 7/29$591
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/125:14 amSLP - TYS
2 stops15h 45mAmerican Airlines
Thu 12/118:26 pmTYS - SLP
2 stops16h 58mAmerican Airlines
Deal found 7/29$721
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/117:12 amSLP - TYS
1 stop28h 29mUnited Airlines
Thu 12/112:30 pmTYS - SLP
2 stops22h 19mUnited Airlines
Deal found 7/29$780

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Mexico to Knoxville that are best for you.

Fly from

Mexico

Fly to

Knoxville

Route

Depart

Return

Price

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Tue 8/12

9:04 am-5:19 pm

1 stop6h 15m

Knoxville McGhee Tyson

Thu 12/11

5:30 am-6:19 pm

1 stop13h 49m

$535

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Sat 8/16

2:45 pm-8:02 pm

2 stops27h 17m

Knoxville McGhee Tyson

Thu 12/11

6:00 am-1:29 pm

3 stops32h 29m

$591

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Tue 8/12

5:14 am-10:59 pm

2 stops15h 45m

Knoxville McGhee Tyson

Thu 12/11

8:26 pm-12:24 pm

2 stops16h 58m

$721

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 8/11

7:12 am-1:41 pm

1 stop28h 29m

Knoxville McGhee Tyson

Thu 12/11

2:30 pm-11:49 am

2 stops22h 19m

$780

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Sat 8/16

4:27 pm-9:47 am

2 stops39h 20m

$323

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Fri 8/15

12:00 pm-1:38 pm

1 stop23h 38m

$364

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Sat 8/16

9:04 am-6:35 pm

1 stop7h 31m

$380

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Mexico to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Knoxville

What is the cheapest month to book a flight from Mexico to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Mexico to Knoxville (average of $294). Flying from Mexico to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MX to TYS?

Find hourly flight availability from Mexico to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Mexico to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Mexico to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Mexico?

    If you book a flight to Knoxville from Mexico, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • Can I find deals for flights from Mexico to Knoxville that include hotel bookings?

    Yes. In addition to deals on Mexico to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Knoxville.

  • Can I find deals for business class flights from Mexico to Knoxville?

    Yes. Cheapflights offers flight deals from Mexico to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Mexico to Knoxville (average of $294). Flying from Mexico to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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