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$235+ Cheap flights from Mexico to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — TYS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Mexico to Knoxville

Keep the following information in mind while searching for Mexico to Knoxville flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$456
(United Airlines)

One-way from

$235
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$669
Provider with most accurate pricing for Mexico City Benito Juarez-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Knoxville McGhee Tyson flights.
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From Mexico to Knoxville McGhee Tyson
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One-way flight from Mexico to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 16% potential increase in price ($127 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Mexico to Knoxville

Best flights from Mexico to Knoxville
Discover carefully curated flight deals from Mexico to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

This Aeromexico deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:52 amSLP - TYS
2 stops15h 52mAeromexico
Tue 4/75:30 amTYS - SLP
2 stops16h 15mAeromexico
Deal found 10/30$455
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:51 amSLP - TYS
1 stop27h 46mUnited Airlines
Tue 4/79:15 amTYS - SLP
1 stop11h 57mUnited Airlines
Deal found 10/30$455
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:24 amSLP - TYS
1 stop9h 14mDelta
Tue 4/77:20 pmTYS - SLP
2 stops22h 32mDelta
Deal found 10/28$457
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/281:35 pmMLM - TYS
1 stop23h 44mAmerican Airlines
Wed 4/17:04 amTYS - MLM
2 stops30h 35mAmerican Airlines
Deal found 10/29$634
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:00 amMLM - TYS
2 stops25h 00mUnited Airlines
Wed 4/17:00 amTYS - MLM
2 stops37h 13mUnited Airlines
Deal found 10/30$686

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mexico to Knoxville that are best for you.

Fly from

Mexico

Fly to

Knoxville

Route

Depart

Return

Price

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Fri 4/3

5:52 am-11:44 pm

2 stops15h 52m

Knoxville McGhee Tyson

Tue 4/7

5:30 am-7:45 pm

2 stops16h 15m

$455

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Fri 4/3

11:51 am-5:37 pm

1 stop27h 46m

Knoxville McGhee Tyson

Tue 4/7

9:15 am-7:12 pm

1 stop11h 57m

$455

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Fri 4/3

9:24 am-8:38 pm

1 stop9h 14m

Knoxville McGhee Tyson

Tue 4/7

7:20 pm-3:52 pm

2 stops22h 32m

$457

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Sat 3/28

1:35 pm-3:19 pm

1 stop23h 44m

Knoxville McGhee Tyson

Wed 4/1

7:04 am-11:39 am

2 stops30h 35m

$634

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Sat 3/28

7:00 am-10:00 am

2 stops25h 00m

Knoxville McGhee Tyson

Wed 4/1

7:00 am-6:13 pm

2 stops37h 13m

$686

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Mon 11/17

9:15 am-6:37 pm

1 stop8h 22m

$235

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Mon 1/5

7:06 pm-6:32 pm

3 stops22h 26m

$424

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Tue 1/6

8:00 am-10:57 am

2 stops25h 57m

$430

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Tue 1/6

7:57 am-5:53 pm

3 stops56h 56m

$447

MoreliaKnoxville

MLM - TYS

MLMTYS

Morelia

Mon 1/5

2:00 pm-12:46 pm

2 stops21h 46m

$532

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 12 results
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Best time to book a flight from Mexico to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Knoxville

What is the cheapest month to book a flight from Mexico to Knoxville?

Currently, November is the cheapest month in which you can book a flight from Mexico to Knoxville (average of $429). Flying from Mexico to Knoxville in February is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MX to TYS?

Find hourly flight availability from Mexico to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from Mexico to Knoxville at noon. Doing so could potentially save you 20% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Mexico?

    If you book a flight to Knoxville from Mexico, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Mexico to Knoxville?

    A quick flight from Mexico to Knoxville can take about 15h 52m. Aeromexico provides one of the quickest options available for as low as $455. Mexico and Knoxville are separated by a distance of 1382 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mexico to Knoxville that include hotel bookings?

    Yes. In addition to deals on Mexico to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Knoxville.

  • Can I find deals for business class flights from Mexico to Knoxville?

    Yes. Cheapflights offers flight deals from Mexico to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from Mexico to Knoxville (average of $429). Flying from Mexico to Knoxville in February is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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