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$126+ Cheap flights from Madison to Knoxville (MSN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Madison to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Madison (MSN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$249
(Delta)

One-way from

$126
(American Airlines)

Popular in

March

Cheapest in

October

Average price

$371
From Madison Truax Field to Knoxville McGhee Tyson
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One-way flight from Madison Truax Field to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 14% potential increase in price ($65 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Madison to Knoxville

Cheapest flights from Madison to Knoxville
Explore the most affordable flight options available from Madison to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:48 pmMSN - TYS
1 stop6h 02mUnited Airlines
Mon 10/137:00 amTYS - MSN
1 stop3h 55mUnited Airlines
Deal found 9/10$249
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:43 pmMSN - TYS
1 stop4h 02mUnited Airlines
Sun 9/287:00 amTYS - MSN
1 stop3h 55mUnited Airlines
Deal found 9/8$259
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:56 pmMSN - TYS
2 stops6h 21mAmerican Airlines
Sat 11/84:56 pmTYS - MSN
1 stop8h 03mAmerican Airlines
Deal found 9/10$313
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:38 pmMSN - TYS
1 stop5h 43mAmerican Airlines
Tue 10/76:00 amTYS - MSN
1 stop5h 35mAmerican Airlines
Deal found 9/10$314
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:30 amMSN - TYS
2 stops10h 40mUnited Airlines
Tue 10/77:00 amTYS - MSN
1 stop5h 45mUnited Airlines
Deal found 9/11$324
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:51 pmMSN - TYS
1 stop6h 37mUnited Airlines
Mon 9/295:53 pmTYS - MSN
1 stop5h 35mUnited Airlines
Deal found 9/10$329
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:26 pmMSN - TYS
1 stop4h 09mDelta
Thu 10/95:44 amTYS - MSN
1 stop5h 48mDelta
Deal found 9/10$339
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2410:16 amMSN - TYS
2 stops7h 34mAmerican Airlines
Sun 9/288:36 pmTYS - MSN
1 stop4h 43mAmerican Airlines
Deal found 9/8$348
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:38 pmMSN - TYS
1 stop5h 43mAmerican Airlines
Sun 9/218:36 pmTYS - MSN
1 stop4h 43mAmerican Airlines
Deal found 9/9$384

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madison to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Madison to Knoxville that are best for you.

Fly from

Madison

Fly to

Knoxville

Route

Depart

Return

Price

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Tue 10/28

7:05 am-3:41 pm

1 stop7h 36m

Knoxville McGhee Tyson

Sat 11/1

6:40 am-10:18 am

1 stop4h 38m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Thu 1/8

10:48 am-6:40 pm

1 stop6h 52m

Knoxville McGhee Tyson

Sun 1/11

5:59 am-10:18 am

1 stop5h 19m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 10/18

5:45 pm-10:50 pm

1 stop4h 05m

Knoxville McGhee Tyson

Wed 11/5

1:52 pm-7:21 pm

1 stop6h 29m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Fri 10/10

3:48 pm-10:50 pm

1 stop6h 02m

Knoxville McGhee Tyson

Mon 10/13

7:00 am-9:55 am

1 stop3h 55m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Tue 11/4

3:37 pm-10:51 pm

1 stop6h 14m

Knoxville McGhee Tyson

Sat 11/8

4:56 pm-11:59 pm

1 stop8h 03m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Wed 2/18

2:00 pm-9:32 pm

1 stop6h 32m

Knoxville McGhee Tyson

Sat 2/21

7:30 am-1:01 pm

1 stop6h 31m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Thu 10/23

5:45 pm-10:50 pm

1 stop4h 05m

Knoxville McGhee Tyson

Mon 10/27

8:26 am-11:44 am

1 stop4h 18m

$249

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Wed 9/24

5:43 pm-10:45 pm

1 stop4h 02m

Knoxville McGhee Tyson

Sun 9/28

7:00 am-9:55 am

1 stop3h 55m

$259

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Wed 2/18

3:52 pm-9:27 pm

1 stop4h 35m

Knoxville McGhee Tyson

Sat 2/21

12:37 pm-5:30 pm

2 stops5h 53m

$274

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 10/4

5:38 pm-12:21 am

1 stop5h 43m

$126

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 12 results
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Best time to book a flight from Madison to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Madison with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madison to Knoxville

What is the cheapest month to book a flight from Madison to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Madison to Knoxville (average of $294). Flying from Madison to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Madison to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Madison to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madison to Knoxville?

    Airlines like Delta, American Airlines, and United Airlines fly from Madison to Knoxville in about 4h 05m. The time it takes to get you to your destination can typically vary by up to 3h 31m. Airlines will cover a distance of 580 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Madison to Knoxville round-trip?

    Currently priced at $172, Delta will fly you from Madison to Knoxville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $248 and $248, respectively. These flights start at 55% lower than the current average price 3 months from now.

  • Can I find deals for flights from Madison to Knoxville that include hotel bookings?

    Yes. In addition to deals on Madison to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madison to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madison to Knoxville.

  • Can I find deals for business class flights from Madison to Knoxville?

    Yes. Cheapflights offers flight deals from Madison to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madison to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Madison to Knoxville (average of $294). Flying from Madison to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Madison to Knoxville

Discover the top 3 airlines that operate flights from Madison to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$172Average$273FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$340FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$438FlexibilityNo cancel feeOn-time69%

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