HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$388+ Cheap flights from Ithaca to Knoxville (ITH - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
ITH — TYS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Ithaca to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ithaca to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Ithaca (ITH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$388
(Delta)
Provider with most accurate pricing for Ithaca Tompkins County-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Ithaca Tompkins County-Knoxville McGhee Tyson flights.
Search Deals
From Ithaca Tompkins County to Knoxville McGhee Tyson
Search Deals

Find flight deals from Ithaca to Knoxville

Cheapest flights from Ithaca to Knoxville
Explore the most affordable flight options available from Ithaca to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:40 pmITH - TYS
1 stop24h 40mUnited Airlines
Tue 11/187:20 pmTYS - ITH
1 stop4h 23mUnited Airlines
Deal found 10/30$538
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:40 pmITH - TYS
1 stop4h 19mUnited Airlines
Sat 1/35:45 amTYS - ITH
1 stop17h 59mUnited Airlines
Deal found 10/28$572
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:40 pmITH - TYS
1 stop4h 19mUnited Airlines
Fri 1/27:23 pmTYS - ITH
1 stop4h 21mUnited Airlines
Deal found 10/29$577
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:40 pmITH - TYS
1 stop19h 08mUnited Airlines
Fri 1/25:45 amTYS - ITH
1 stop17h 59mUnited Airlines
Deal found 10/28$621
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:40 pmITH - TYS
1 stop15h 16mUnited Airlines
Fri 1/27:23 pmTYS - ITH
1 stop4h 21mUnited Airlines
Deal found 10/29$626
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:40 pmITH - TYS
1 stop15h 16mUnited Airlines
Sat 1/35:45 amTYS - ITH
1 stop17h 59mUnited Airlines
Deal found 10/29$651
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:40 pmITH - TYS
1 stop4h 19mUnited Airlines
Sun 1/45:45 amTYS - ITH
1 stop12h 56mUnited Airlines
Deal found 10/28$662

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ithaca to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Ithaca to Knoxville that are best for you.

Fly from

Ithaca

Fly to

Knoxville

Route

Depart

Return

Price

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Tue 2/24

2:00 pm-9:32 pm

2 stops7h 32m

Knoxville McGhee Tyson

Sat 2/28

12:00 pm-1:19 pm

2 stops25h 19m

$388

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Tue 2/24

6:00 am-10:49 am

1 stop4h 49m

Knoxville McGhee Tyson

Sat 2/28

7:25 pm-11:42 pm

1 stop4h 17m

$448

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Fri 11/14

7:40 pm-8:20 pm

1 stop24h 40m

Knoxville McGhee Tyson

Tue 11/18

7:20 pm-11:43 pm

1 stop4h 23m

$538

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Mon 12/29

7:40 pm-11:59 pm

1 stop4h 19m

Knoxville McGhee Tyson

Fri 1/2

5:45 am-11:44 pm

1 stop17h 59m

$572

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Mon 12/29

7:40 pm-11:59 pm

1 stop4h 19m

Knoxville McGhee Tyson

Sat 1/3

5:45 am-11:44 pm

1 stop17h 59m

$572

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Sun 12/28

7:40 pm-10:56 am

1 stop15h 16m

Knoxville McGhee Tyson

Sat 1/3

5:45 am-11:44 pm

1 stop17h 59m

$621

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Tue 12/30

7:40 pm-2:48 pm

1 stop19h 08m

Knoxville McGhee Tyson

Fri 1/2

5:45 am-11:44 pm

1 stop17h 59m

$621

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Tue 12/30

7:40 pm-2:48 pm

1 stop19h 08m

Knoxville McGhee Tyson

Sat 1/3

5:45 am-11:44 pm

1 stop17h 59m

$621

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Compare providers for flights from Ithaca to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Ithaca to Knoxville in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Ithaca-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Ithaca-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Ithaca-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Ithaca-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Ithaca-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Ithaca to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ithaca with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ithaca to Knoxville

What is the cheapest month to book a flight from Ithaca to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Ithaca to Knoxville (average of $144). Flying from Ithaca to Knoxville in January is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Ithaca to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Ithaca to Knoxville?

    Airlines like United Airlines fly from Ithaca to Knoxville in about 4h 49m. The time it takes to get you to your destination can typically vary by up to . Ithaca and Knoxville are separated by a distance of 612 mi.

  • Can I find deals for flights from Ithaca to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ithaca to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ithaca to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ithaca to Knoxville.

  • Can I find deals for business class flights from Ithaca to Knoxville?

    Yes. Cheapflights offers flight deals from Ithaca to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ithaca to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Ithaca to Knoxville (average of $144). Flying from Ithaca to Knoxville in January is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ithaca to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
LaGuardia to Nashville flights
Newark to Nashville flights
John F Kennedy Intl to Memphis flights
Newark to Memphis flights
LaGuardia to Memphis flights
LaGuardia to Knoxville flights
John F Kennedy Intl to Knoxville flights
Stewart to Nashville flights
Newark to Knoxville flights
Buffalo to Nashville flights
Albany to Nashville flights
White Plains to Nashville flights
Rochester to Nashville flights
LaGuardia to Chattanooga flights
Syracuse to Memphis flights
Syracuse to Nashville flights
Newark to Chattanooga flights
John F Kennedy Intl to Chattanooga flights
Stewart to Knoxville flights
Syracuse to Knoxville flights
Islip to Nashville flights
John F Kennedy Intl to Blountville flights
White Plains to Memphis flights
Newark to Blountville flights
Stewart to Memphis flights
LaGuardia to Blountville flights
Albany to Knoxville flights
Rochester to Knoxville flights
White Plains to Chattanooga flights
Buffalo to Knoxville flights
Rochester to Memphis flights
Albany to Chattanooga flights
White Plains to Knoxville flights
Albany to Memphis flights
Buffalo to Memphis flights
Buffalo to Chattanooga flights
Syracuse to Chattanooga flights
Islip to Knoxville flights
Ithaca to Nashville flights
Binghamton to Nashville flights
Syracuse to Blountville flights
Rochester to Chattanooga flights
Rochester to Blountville flights
Watertown to Nashville flights
Ithaca to Chattanooga flights
Albany to Blountville flights
Plattsburgh to Nashville flights
Buffalo to Blountville flights
Elmira to Nashville flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.