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$274+ Cheap flights from Ithaca to Knoxville (ITH - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
ITH — TYS
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Ithaca to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Ithaca (ITH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$324
(Delta)

One-way from

$274
(United Airlines)
From Ithaca Tompkins County to Knoxville McGhee Tyson
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One-way flight from Ithaca Tompkins County to Knoxville McGhee Tyson
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Find flight deals from Ithaca to Knoxville

Cheapest flights from Ithaca to Knoxville
Explore the most affordable flight options available from Ithaca to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:10 amITH - TYS
1 stop4h 19mUnited Airlines
Sat 10/47:00 amTYS - ITH
2 stops11h 38mUnited Airlines
Deal found 9/15$359
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:10 amITH - TYS
1 stop4h 19mUnited Airlines
Sat 10/188:50 amTYS - ITH
2 stops9h 48mUnited Airlines
Deal found 9/17$479
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/135:40 amITH - TYS
2 stops9h 03mDelta
Sat 10/186:15 amTYS - ITH
2 stops6h 58mDelta
Deal found 9/17$539
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amITH - TYS
1 stop17h 59mUnited Airlines
Fri 1/25:45 amTYS - ITH
1 stop17h 59mUnited Airlines
Deal found 9/15$577
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:53 pmITH - TYS
1 stop14h 36mUnited Airlines
Mon 10/68:50 amTYS - ITH
2 stops14h 53mUnited Airlines
Deal found 9/17$677
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:40 pmITH - TYS
1 stop4h 19mUnited Airlines
Fri 12/269:50 amTYS - ITH
1 stop13h 54mUnited Airlines
Deal found 9/17$783

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ithaca to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Ithaca to Knoxville that are best for you.

Fly from

Ithaca

Fly to

Knoxville

Route

Depart

Return

Price

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Tue 9/30

6:10 am-10:29 am

1 stop4h 19m

Knoxville McGhee Tyson

Sat 10/4

7:00 am-6:38 pm

2 stops11h 38m

$359

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Mon 10/13

6:10 am-10:29 am

1 stop4h 19m

Knoxville McGhee Tyson

Sat 10/18

8:50 am-6:38 pm

2 stops9h 48m

$479

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Mon 10/13

5:40 am-2:43 pm

2 stops9h 03m

Knoxville McGhee Tyson

Sat 10/18

6:15 am-1:13 pm

2 stops6h 58m

$539

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Thu 10/2

7:53 pm-10:29 am

1 stop14h 36m

Knoxville McGhee Tyson

Mon 10/6

8:50 am-11:43 pm

2 stops14h 53m

$677

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Mon 10/13

6:10 am-10:29 am

1 stop4h 19m

$274

IthacaKnoxville

ITH - TYS

ITHTYS

Ithaca Tompkins County

Sun 10/12

7:53 pm-9:11 pm

1 stop25h 18m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Ithaca to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ithaca with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ithaca to Knoxville

What is the cheapest month to book a flight from Ithaca to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Ithaca to Knoxville (average of $295). Flying from Ithaca to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Ithaca to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Ithaca to Knoxville?

    Airlines like United Airlines and Delta fly from Ithaca to Knoxville in about 4h 19m. The time it takes to get you to your destination can typically vary by up to 4h 44m. Ithaca and Knoxville are separated by a distance of 612 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Ithaca to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ithaca to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ithaca to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ithaca to Knoxville.

  • Can I find deals for business class flights from Ithaca to Knoxville?

    Yes. Cheapflights offers flight deals from Ithaca to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ithaca to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Ithaca to Knoxville (average of $295). Flying from Ithaca to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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