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$117+ Cheap flights from Indianapolis to Knoxville (IND - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
nov. 27 — dic. 41
jue. 11/27
jue. 12/4
1 adult, Economy
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Cheap flight deals from Indianapolis to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$208
(Kiwi.com)

One-way from

$117
(Kiwi.com)

Popular in

March

Cheapest in

December

Average price

$428
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
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From Indianapolis to Knoxville McGhee Tyson
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One-way flight from Indianapolis to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 13% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Indianapolis to Knoxville

Cheapest flights from Indianapolis to Knoxville
Explore the most affordable flight options available from Indianapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/195:05 amIND - TYS
1 stop7h 52mMultiple Airlines
lun. 11/2412:12 pmTYS - IND
1 stop27h 07mMultiple Airlines
Deal found 10/26$208
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/73:15 pmIND - TYS
1 stop21h 36mAllegiant Air
vie. 12/127:49 pmTYS - IND
1 stop20h 50mAllegiant Air
Deal found 10/26$224
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:30 amIND - TYS
1 stop11h 29mMultiple Airlines
dom. 12/146:30 amTYS - IND
1 stop13h 23mMultiple Airlines
Deal found 10/26$236
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/256:00 amIND - TYS
1 stop3h 37mDelta
mar. 12/27:39 amTYS - IND
1 stop5h 49mDelta
Deal found 10/26$239
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/152:20 pmIND - TYS
1 stop4h 42mDelta
lun. 11/178:07 pmTYS - IND
1 stop4h 19mDelta
Deal found 10/26$244
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/173:22 pmIND - TYS
1 stop7h 52mMultiple Airlines
jue. 11/204:53 pmTYS - IND
1 stop15h 15mMultiple Airlines
Deal found 10/26$251
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/103:22 pmIND - TYS
1 stop7h 52mMultiple Airlines
vie. 11/142:02 pmTYS - IND
2 stops30h 39mMultiple Airlines
Deal found 10/26$258
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:30 amIND - TYS
1 stop4h 34mDelta
lun. 11/108:07 pmTYS - IND
1 stop4h 19mDelta
Deal found 10/26$264
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/910:21 pmIND - TYS
1 stop15h 36mMultiple Airlines
mié. 11/124:32 pmTYS - IND
1 stop24h 46mMultiple Airlines
Deal found 10/26$272
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/118:59 pmIND - TYS
1 stop25h 15mMultiple Airlines
vie. 11/149:38 pmTYS - IND
1 stop12h 05mMultiple Airlines
Deal found 10/26$273

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Indianapolis

Fly to

Knoxville

Route

Depart

Return

Price

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

mié. 11/19

5:05 am-12:57 pm

1 stop7h 52m

Knoxville McGhee Tyson

lun. 11/24

12:12 pm-3:19 pm

1 stop27h 07m

$208

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

dom. 12/7

3:15 pm-12:51 pm

1 stop21h 36m

Knoxville McGhee Tyson

vie. 12/12

7:49 pm-4:39 pm

1 stop20h 50m

$224

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

sáb. 2/21

7:50 am-11:47 am

1 stop3h 57m

Knoxville McGhee Tyson

mié. 2/25

7:30 am-1:32 pm

1 stop6h 02m

$239

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

mar. 11/25

6:00 am-9:37 am

1 stop3h 37m

Knoxville McGhee Tyson

mar. 12/2

7:39 am-1:28 pm

1 stop5h 49m

$239

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

sáb. 11/15

2:20 pm-7:02 pm

1 stop4h 42m

Knoxville McGhee Tyson

lun. 11/17

8:07 pm-12:26 am

1 stop4h 19m

$244

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

vie. 12/12

7:30 am-6:59 pm

1 stop11h 29m

Knoxville McGhee Tyson

lun. 12/15

1:05 pm-7:43 am

2 stops18h 38m

$279

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

dom. 12/7

8:00 am-10:42 pm

1 stop14h 42m

Knoxville McGhee Tyson

vie. 12/12

1:05 pm-7:43 am

2 stops18h 38m

$290

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

vie. 2/13

6:00 am-11:03 am

1 stop5h 03m

Knoxville McGhee Tyson

dom. 2/15

11:16 am-4:45 pm

1 stop5h 29m

$293

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

lun. 11/17

3:22 pm-11:14 pm

1 stop7h 52m

$117

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

lun. 11/24

11:18 am-3:07 pm

1 stop3h 49m

$125

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 17 results
1
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Compare providers for flights from Indianapolis to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Knoxville

What is the cheapest month to book a flight from Indianapolis to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $190). Flying from Indianapolis to Knoxville in February is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to TYS?

Find hourly flight availability from Indianapolis to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 28, 2025.

It’s optimal to fly from Indianapolis to Knoxville at noon. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated octubre 28, 2025.
See what other customers who have flown with Delta and American Airlines from Indianapolis to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Knoxville?

    For as low as $239, Allegiant Air can have you in Knoxville from Indianapolis in 3h 57m. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Knoxville round-trip?

    According to our current data, American Airlines ($208), and Delta ($217) offers the cheapest pricing from Indianapolis to Knoxville. American Airlines is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Indianapolis to Knoxville one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $117. American Airlines flights start at $125 while deals on Delta start at $125 one-way.

  • Can I find deals for flights from Indianapolis to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Knoxville.

  • Can I find deals for business class flights from Indianapolis to Knoxville?

    Yes. Cheapflights offers flight deals from Indianapolis to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $190). Flying from Indianapolis to Knoxville in February is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Indianapolis to Knoxville

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Top 2 airlines flying from Indianapolis to Knoxville

Discover the top 2 airlines that operate flights from Indianapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$365FlexibilityNo cancel feeOn-time71%
DeltaCheapest$217Average$291FlexibilityNo cancel feeOn-timeN/A

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