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$100+ Cheap flights from Indianapolis to Knoxville (IND - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Indianapolis to Knoxville

Cheapest flights from Indianapolis to Knoxville
Explore the most affordable flight options available from Indianapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:00 am
IND
-
TYS
1 stop28h 16m
Multiple Airlines
Mon 4/136:20 pm
TYS
-
IND
1 stop16h 51m
Multiple Airlines
Deal found 3/6$240
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
IND
-
TYS
1 stop4h 08m
United Airlines
Thu 4/97:00 am
TYS
-
IND
1 stop5h 52m
United Airlines
Deal found 3/5$287
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:40 am
IND
-
TYS
2 stops10h 25m
Southwest
Tue 4/77:05 am
TYS
-
IND
1 stop5h 35m
Southwest
Deal found 3/7$292
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:45 am
IND
-
TYS
1 stop5h 05m
United Airlines
Tue 4/217:20 pm
TYS
-
IND
1 stop4h 37m
United Airlines
Deal found 3/8$294
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:15 am
IND
-
TYS
2 stops12h 05m
Southwest
Mon 4/276:45 pm
TYS
-
IND
1 stop3h 15m
Southwest
Deal found 3/5$298
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:09 pm
IND
-
TYS
1 stop23h 12m
Multiple Airlines
Thu 4/95:10 pm
TYS
-
IND
2 stops18h 13m
Multiple Airlines
Deal found 3/6$299
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:47 pm
IND
-
TYS
1 stop4h 27m
Delta
Fri 5/87:33 pm
TYS
-
IND
1 stop5h 10m
Delta
Deal found 3/6$302
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:50 pm
IND
-
TYS
1 stop6h 53m
Multiple Airlines
Thu 4/911:27 am
TYS
-
IND
2 stops23h 56m
Multiple Airlines
Deal found 3/5$304
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
IND
-
TYS
1 stop5h 55m
Multiple Airlines
Sun 5/1012:55 pm
TYS
-
IND
1 stop23h 56m
Multiple Airlines
Deal found 3/9$306
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:10 am
IND
-
TYS
1 stop5h 42m
Delta
Sun 4/265:40 am
TYS
-
IND
1 stop3h 20m
Delta
Deal found 3/8$307

Find flight deals from Indianapolis to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$240
(Kiwi.com)

One-way from

$100
(Kiwi.com)

Popular in

May

Cheapest in

April

Average price

$351
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
Search Deals
From Indianapolis to Knoxville McGhee Tyson
Search Deals
One-way flight from Indianapolis to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 4/20

8:15 am-8:20 pm

2 stops12h 05m

Knoxville McGhee Tyson

Mon 4/27

6:45 pm-10:00 pm

1 stop3h 15m

$298
Quickest round-trip

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 4/21

10:10 am-3:52 pm

1 stop5h 42m

Knoxville McGhee Tyson

Sun 4/26

5:40 am-9:00 am

1 stop3h 20m

$307

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 6/4

8:51 pm-11:39 pm

2 stops26h 48m

Knoxville McGhee Tyson

Thu 7/2

6:08 pm-12:24 pm

1 stop18h 16m

$314

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 4/2

9:45 am-6:45 pm

1 stop9h 00m

Knoxville McGhee Tyson

Thu 4/9

8:05 am-4:00 pm

2 stops7h 55m

$352

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 8/22

5:54 am-10:36 am

1 stop4h 42m

Knoxville McGhee Tyson

Wed 8/26

3:25 pm-11:26 pm

1 stop8h 01m

$377

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 4/7

8:07 pm-10:08 am

1 stop14h 01m

Knoxville McGhee Tyson

Tue 4/14

10:49 am-4:52 pm

1 stop6h 03m

$409

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 6/4

6:45 am-9:10 pm

2 stops14h 25m

Knoxville McGhee Tyson

Thu 7/2

7:30 am-6:05 pm

2 stops10h 35m

$409
Cheapest one-way

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 5/8

6:11 pm-11:06 am

1 stop16h 55m

$100

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 5/15

6:11 pm-11:06 am

1 stop16h 55m

$116

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 3/31

7:45 am-1:40 pm

1 stop5h 55m

$132

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Indianapolis to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Knoxville

What is the cheapest month to book a flight from Indianapolis to Knoxville?

Currently, February is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $180). Flying from Indianapolis to Knoxville in March is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 10, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Indianapolis to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,409 reviews
Delta
7.9
Good
8,276 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,413 reviews
Delta
7.9
Good
8,276 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Knoxville?

    For as low as $307, Southwest can have you in Knoxville from Indianapolis in 5h 42m. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Knoxville round-trip?

    According to our current data, American Airlines ($208), Delta ($217), and United Airlines ($328) offers the cheapest pricing from Indianapolis to Knoxville. American Airlines is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Indianapolis to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Knoxville.

  • Can I find deals for business class flights from Indianapolis to Knoxville?

    Yes. Cheapflights offers flight deals from Indianapolis to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Knoxville?

    Currently, February is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $180). Flying from Indianapolis to Knoxville in March is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top 3 airlines flying from Indianapolis to Knoxville

Discover the top 3 airlines that operate flights from Indianapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$383FlexibilityNo cancel feeOn-time71%
DeltaCheapest$217Average$283FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$328Average$456FlexibilityNo cancel feeOn-time69%

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