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Knoxville

$112+ Cheap flights from Indianapolis to Knoxville (IND - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Indianapolis to Knoxville

Cheapest flights from Indianapolis to Knoxville
Explore the most affordable flight options available from Indianapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:06 pmIND - TYS
1 stop5h 01mAmerican Airlines
Mon 12/297:48 amTYS - IND
1 stop5h 30mAmerican Airlines
Deal found 12/10$315
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amIND - TYS
1 stop15h 34mAllegiant Air
Tue 12/238:30 amTYS - IND
1 stop27h 38mAllegiant Air
Deal found 12/9$318
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amIND - TYS
1 stop15h 34mMultiple Airlines
Tue 12/238:30 amTYS - IND
2 stops27h 03mMultiple Airlines
Deal found 12/9$337
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:48 amIND - TYS
1 stop27h 12mMultiple Airlines
Sat 1/37:15 amTYS - IND
1 stop23h 58mMultiple Airlines
Deal found 12/9$423
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:00 amIND - TYS
1 stop14h 42mMultiple Airlines
Tue 12/164:52 pmTYS - IND
2 stops38h 21mMultiple Airlines
Deal found 12/10$439
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:11 pmIND - TYS
1 stop3h 36mAmerican Airlines
Wed 12/317:35 amTYS - IND
1 stop7h 52mAmerican Airlines
Deal found 12/10$440
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:30 amIND - TYS
1 stop4h 54mAmerican Airlines
Tue 12/307:48 amTYS - IND
1 stop5h 30mAmerican Airlines
Deal found 12/11$467
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amIND - TYS
1 stop15h 11mMultiple Airlines
Fri 12/269:25 pmTYS - IND
1 stop14h 08mMultiple Airlines
Deal found 12/11$476
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:30 pmIND - TYS
1 stop5h 28mAmerican Airlines
Tue 12/235:00 amTYS - IND
1 stop4h 22mAmerican Airlines
Deal found 12/9$482

Find flight deals from Indianapolis to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$195
(Mytrip)

One-way from

$112
(American Airlines)

Popular in

March

Cheapest in

November

Average price

$298
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
Search Deals
From Indianapolis to Knoxville McGhee Tyson
Search Deals
One-way flight from Indianapolis to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Indianapolis

Fly to

Knoxville

Route

Depart

Return

Price

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 1/26

10:38 am-5:28 pm

1 stop6h 50m

Knoxville McGhee Tyson

Wed 1/28

4:47 pm-7:31 pm

1 stop26h 44m

$212

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 1/26

10:38 am-5:28 pm

1 stop6h 50m

Knoxville McGhee Tyson

Thu 1/29

9:29 am-9:43 am

2 stops24h 14m

$220

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 1/7

12:38 pm-8:39 am

1 stop20h 01m

Knoxville McGhee Tyson

Wed 1/14

4:47 pm-10:48 pm

1 stop30h 01m

$250

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 1/7

7:01 am-12:46 pm

1 stop5h 45m

Knoxville McGhee Tyson

Thu 1/8

4:00 pm-9:35 pm

1 stop5h 35m

$304

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 1/7

11:11 am-3:19 pm

1 stop4h 08m

Knoxville McGhee Tyson

Thu 1/8

5:40 am-10:04 am

1 stop4h 24m

$304

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 3/18

10:05 am-4:06 pm

1 stop6h 01m

Knoxville McGhee Tyson

Sun 3/22

5:30 am-8:56 am

1 stop3h 26m

$312

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 12/25

1:06 pm-6:07 pm

1 stop5h 01m

$112

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 12/18

5:53 pm-2:55 pm

1 stop21h 02m

$131

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 12/20

6:00 am-9:34 pm

1 stop15h 34m

$151

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 3/13

12:15 pm-9:15 pm

2 stops9h 00m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 12 results
1
2

Compare providers for flights from Indianapolis to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Knoxville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Knoxville

What is the cheapest month to book a flight from Indianapolis to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $190). Flying from Indianapolis to Knoxville in February is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to TYS?

Find hourly flight availability from Indianapolis to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s optimal to fly from Indianapolis to Knoxville at noon. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta and American Airlines from Indianapolis to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Indianapolis to Knoxville round-trip?

    According to our current data, Delta ($217), and American Airlines ($218) offers the cheapest pricing from Indianapolis to Knoxville. Delta is priced at 36% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Indianapolis to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Knoxville.

  • Can I find deals for business class flights from Indianapolis to Knoxville?

    Yes. Cheapflights offers flight deals from Indianapolis to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $190). Flying from Indianapolis to Knoxville in February is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from Indianapolis to Knoxville

Discover the top 2 airlines that operate flights from Indianapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$217Average$291FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$356FlexibilityNo cancel feeOn-time71%

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