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$92+ Cheap flights from Indianapolis to Knoxville (IND - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Indianapolis to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$183
(American Airlines)

One-way from

$92
(American Airlines)

Popular in

March

Cheapest in

June

Average price

$268
From Indianapolis to Knoxville McGhee Tyson
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One-way flight from Indianapolis to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 14% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Indianapolis to Knoxville

Cheapest flights from Indianapolis to Knoxville
Explore the most affordable flight options available from Indianapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:30 amIND - TYS
1 stop4h 34mDelta
Sun 10/268:10 pmTYS - IND
1 stop4h 12mDelta
Deal found 9/9$218
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:45 amIND - TYS
1 stop11h 49mMultiple Airlines
Fri 10/38:38 amTYS - IND
1 stop15h 00mMultiple Airlines
Deal found 9/10$228
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:58 pmIND - TYS
1 stop22h 36mMultiple Airlines
Mon 9/2910:45 amTYS - IND
1 stop8h 16mMultiple Airlines
Deal found 9/10$230
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:30 amIND - TYS
1 stop5h 00mAllegiant Air
Thu 10/23:13 pmTYS - IND
1 stop5h 35mAllegiant Air
Deal found 9/10$237
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:42 amIND - TYS
1 stop4h 01mAmerican Airlines
Mon 11/2412:01 pmTYS - IND
1 stop3h 49mAmerican Airlines
Deal found 9/9$239
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:30 amIND - TYS
1 stop12h 01mAllegiant Air
Fri 10/38:38 amTYS - IND
1 stop15h 00mAllegiant Air
Deal found 9/10$240
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:05 amIND - TYS
1 stop3h 51mDelta
Sun 9/285:45 amTYS - IND
1 stop3h 12mDelta
Deal found 9/9$249
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:30 amIND - TYS
1 stop12h 01mAllegiant Air
Thu 10/23:13 pmTYS - IND
1 stop5h 35mAllegiant Air
Deal found 9/10$253
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:00 amIND - TYS
1 stop6h 36mAmerican Airlines
Sat 9/276:25 amTYS - IND
1 stop7h 27mAmerican Airlines
Deal found 9/11$254
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:00 amIND - TYS
1 stop3h 45mDelta
Sun 10/198:35 pmTYS - IND
1 stop3h 47mDelta
Deal found 9/8$259
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:56 pmIND - TYS
1 stop4h 54mAmerican Airlines
Mon 10/278:37 pmTYS - IND
1 stop3h 42mAmerican Airlines
Deal found 9/10$264
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:30 amIND - TYS
1 stop5h 00mMultiple Airlines
Thu 10/25:44 pmTYS - IND
2 stops15h 34mMultiple Airlines
Deal found 9/10$268

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Indianapolis

Fly to

Knoxville

Route

Depart

Return

Price

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 9/29

5:45 am-5:34 pm

1 stop11h 49m

Knoxville McGhee Tyson

Fri 10/3

8:38 am-11:38 pm

1 stop15h 00m

$228

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 9/25

6:58 pm-5:34 pm

1 stop22h 36m

Knoxville McGhee Tyson

Mon 9/29

10:45 am-7:01 pm

1 stop8h 16m

$230

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 9/26

7:30 am-12:30 pm

1 stop5h 00m

Knoxville McGhee Tyson

Thu 10/2

3:13 pm-8:48 pm

1 stop5h 35m

$237

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 11/20

8:42 am-12:43 pm

1 stop4h 01m

Knoxville McGhee Tyson

Mon 11/24

12:01 pm-3:50 pm

1 stop3h 49m

$239

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 9/28

8:30 am-8:31 pm

1 stop12h 01m

Knoxville McGhee Tyson

Fri 10/3

8:38 am-11:38 pm

1 stop15h 00m

$240

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 9/24

7:05 am-10:56 am

1 stop3h 51m

Knoxville McGhee Tyson

Sun 9/28

5:45 am-8:57 am

1 stop3h 12m

$249

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 9/24

7:08 am-12:21 pm

1 stop5h 13m

Knoxville McGhee Tyson

Sat 9/27

7:45 pm-11:10 pm

1 stop3h 25m

$249

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 9/26

3:58 pm-9:19 pm

1 stop5h 21m

Knoxville McGhee Tyson

Mon 9/29

7:18 am-3:18 pm

1 stop8h 00m

$249

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 9/24

1:13 pm-6:50 pm

1 stop5h 37m

Knoxville McGhee Tyson

Sun 9/28

7:18 am-3:18 pm

1 stop8h 00m

$249

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 9/28

8:30 am-8:31 pm

1 stop12h 01m

Knoxville McGhee Tyson

Thu 10/2

3:13 pm-8:48 pm

1 stop5h 35m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 17 results
1
2

Best time to book a flight from Indianapolis to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Knoxville

What is the cheapest month to book a flight from Indianapolis to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $294). Flying from Indianapolis to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to TYS?

Find hourly flight availability from Indianapolis to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Indianapolis to Knoxville at noon. By choosing this option you can save up to 35% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta and American Airlines from Indianapolis to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Knoxville?

    For as low as $239, Allegiant Air can have you in Knoxville from Indianapolis in 4h 01m. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Knoxville round-trip?

    According to our current data, American Airlines ($208), and Delta ($217) offers the cheapest pricing from Indianapolis to Knoxville. American Airlines is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Indianapolis to Knoxville one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $92. Allegiant Air flights start at $116 while deals on United Airlines start at $126 one-way.

  • Can I find deals for flights from Indianapolis to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Knoxville.

  • Can I find deals for business class flights from Indianapolis to Knoxville?

    Yes. Cheapflights offers flight deals from Indianapolis to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $294). Flying from Indianapolis to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Indianapolis to Knoxville

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Top 2 airlines flying from Indianapolis to Knoxville

Discover the top 2 airlines that operate flights from Indianapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$309FlexibilityNo cancel feeOn-time71%
DeltaCheapest$217Average$338FlexibilityNo cancel feeOn-timeN/A

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