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Knoxville

$101+ Cheap flights from Indianapolis to Knoxville (IND - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Indianapolis to Knoxville

Cheapest flights from Indianapolis to Knoxville
Explore the most affordable flight options available from Indianapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/89:00 am
IND
-
TYS
1 stop14h 10m
Allegiant Air
Thu 2/1211:50 am
TYS
-
IND
1 stop24h 03m
Allegiant Air
Deal found 1/24$248
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 am
IND
-
TYS
1 stop6h 00m
Multiple Airlines
Fri 3/138:40 am
TYS
-
IND
1 stop26h 19m
Multiple Airlines
Deal found 1/25$250
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
IND
-
TYS
1 stop4h 12m
United Airlines
Wed 3/46:45 am
TYS
-
IND
1 stop4h 41m
United Airlines
Deal found 1/26$251
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:12 pm
IND
-
TYS
2 stops30h 55m
Multiple Airlines
Wed 3/43:54 pm
TYS
-
IND
1 stop6h 54m
Multiple Airlines
Deal found 1/26$278
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/89:00 am
IND
-
TYS
1 stop14h 10m
Multiple Airlines
Thu 2/127:00 am
TYS
-
IND
2 stops11h 31m
Multiple Airlines
Deal found 1/24$287
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:08 pm
IND
-
TYS
1 stop3h 47m
American Airlines
Fri 5/85:00 am
TYS
-
IND
1 stop4h 41m
American Airlines
Deal found 1/23$294
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:00 am
IND
-
TYS
1 stop5h 05m
Southwest
Tue 7/2812:45 pm
TYS
-
IND
1 stop6h 45m
Southwest
Deal found 1/26$307
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:08 pm
IND
-
TYS
1 stop6h 36m
United Airlines
Wed 2/259:40 am
TYS
-
IND
1 stop4h 59m
United Airlines
Deal found 1/25$311
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:35 am
IND
-
TYS
1 stop5h 10m
American Airlines
Fri 2/205:47 pm
TYS
-
IND
1 stop6h 55m
American Airlines
Deal found 1/24$314

Find flight deals from Indianapolis to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$250
(Kiwi.com)

One-way from

$101
(Trip.com)

Popular in

March

Cheapest in

November

Average price

$547
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
Search Deals
From Indianapolis to Knoxville McGhee Tyson
Search Deals
One-way flight from Indianapolis to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Indianapolis to Knoxville that are best for you.

Fly from

Indianapolis

Fly to

Knoxville

Route

Depart

Return

Price

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 2/8

9:00 am-11:10 pm

1 stop14h 10m

Knoxville McGhee Tyson

Thu 2/12

11:50 am-11:53 am

1 stop24h 03m

$248

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 2/25

6:00 am-10:12 am

1 stop4h 12m

Knoxville McGhee Tyson

Wed 3/4

6:45 am-11:26 am

1 stop4h 41m

$251

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 2/25

3:12 pm-10:07 pm

2 stops30h 55m

Knoxville McGhee Tyson

Wed 3/4

3:54 pm-10:48 pm

1 stop6h 54m

$278

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sun 2/8

9:00 am-11:10 pm

1 stop14h 10m

Knoxville McGhee Tyson

Thu 2/12

7:00 am-6:31 pm

2 stops11h 31m

$287

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Mon 3/9

6:00 am-12:00 pm

1 stop6h 00m

Knoxville McGhee Tyson

Fri 3/13

6:21 pm-4:13 pm

2 stops21h 52m

$303

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 2/21

2:00 pm-8:37 pm

1 stop6h 37m

Knoxville McGhee Tyson

Wed 2/25

9:10 am-3:48 pm

1 stop6h 38m

$311

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 2/19

5:35 am-10:45 am

1 stop5h 10m

Knoxville McGhee Tyson

Fri 2/20

5:47 pm-12:42 am

1 stop6h 55m

$314

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 3/3

8:18 pm-10:10 am

1 stop13h 52m

$101

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Tue 3/24

6:15 am-10:40 am

1 stop28h 25m

$117

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Thu 2/5

8:31 pm-3:30 pm

2 stops18h 59m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 11 results
1
2

Compare providers for flights from Indianapolis to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Knoxville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Knoxville flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Knoxville

What is the cheapest month to book a flight from Indianapolis to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $190). Flying from Indianapolis to Knoxville in December is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Indianapolis to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 26, 2026.
See what other customers who have flown with Delta and American Airlines from Indianapolis to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Knoxville?

    For as low as $251, Allegiant Air can have you in Knoxville from Indianapolis in 4h 12m. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Knoxville round-trip?

    According to our current data, Delta ($217), and American Airlines ($218) offers the cheapest pricing from Indianapolis to Knoxville. Delta is priced at 39% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Indianapolis to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Knoxville.

  • Can I find deals for business class flights from Indianapolis to Knoxville?

    Yes. Cheapflights offers flight deals from Indianapolis to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Indianapolis to Knoxville (average of $190). Flying from Indianapolis to Knoxville in December is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Indianapolis to Knoxville

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Top 2 airlines flying from Indianapolis to Knoxville

Discover the top 2 airlines that operate flights from Indianapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$217Average$283FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$377FlexibilityNo cancel feeOn-time71%

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