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$146+ Cheap flights from Knoxville to Indianapolis (TYS - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Jun 25 — Jul 21
Thu 6/25
Thu 7/2
1 adult, Economy
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Cheap flight deals from Knoxville to Indianapolis

Cheapest flights from Knoxville to Indianapolis
Explore the most affordable flight options available from Knoxville to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:05 pm
TYS
-
IND
1 stop25h 00m
Allegiant Air
Fri 7/176:00 am
IND
-
TYS
1 stop15h 15m
Allegiant Air
Deal found 5/23$267
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:00 am
TYS
-
IND
1 stop5h 38m
American Airlines
Tue 6/306:55 am
IND
-
TYS
1 stop4h 03m
American Airlines
Deal found 5/25$279
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:20 pm
TYS
-
IND
1 stop14h 38m
Multiple Airlines
Sun 7/1210:18 am
IND
-
TYS
1 stop12h 45m
Multiple Airlines
Deal found 5/25$281
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 am
TYS
-
IND
1 stop6h 29m
Allegiant Air
Sun 7/263:50 pm
IND
-
TYS
1 stop26h 24m
Allegiant Air
Deal found 5/25$283
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 am
TYS
-
IND
1 stop3h 22m
Delta
Tue 6/236:00 am
IND
-
TYS
1 stop3h 38m
Delta
Deal found 5/24$291
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:00 am
TYS
-
IND
1 stop17h 05m
Allegiant Air
Tue 7/215:12 pm
IND
-
TYS
1 stop19h 03m
Allegiant Air
Deal found 5/25$292
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:05 pm
TYS
-
IND
1 stop25h 00m
Multiple Airlines
Fri 7/1712:20 pm
IND
-
TYS
2 stops11h 13m
Multiple Airlines
Deal found 5/23$313
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:56 pm
TYS
-
IND
1 stop5h 03m
Multiple Airlines
Wed 6/1012:14 pm
IND
-
TYS
2 stops32h 16m
Multiple Airlines
Deal found 5/21$317
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:00 am
TYS
-
IND
1 stop5h 47m
United Airlines
Mon 8/314:25 pm
IND
-
TYS
1 stop4h 28m
United Airlines
Deal found 5/21$322
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:19 pm
TYS
-
IND
1 stop4h 40m
United Airlines
Wed 6/245:35 am
IND
-
TYS
1 stop5h 07m
United Airlines
Deal found 5/26$328
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
-
IND
2 stops15h 15m
Southwest
Tue 6/305:05 am
IND
-
TYS
1 stop11h 55m
Southwest
Deal found 5/25$330
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 am
TYS
-
IND
1 stop4h 04m
American Airlines
Thu 6/187:45 am
IND
-
TYS
1 stop5h 28m
American Airlines
Deal found 5/21$334

Find flight deals from Knoxville to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$267
(Kiwi.com)

One-way from

$146
(Delta)

Popular in

March

Cheapest in

August

Average price

$439
Provider with most accurate pricing for Knoxville McGhee Tyson-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Indianapolis flights.
Search Deals
From Knoxville McGhee Tyson to Indianapolis
Search Deals
One-way flight from Knoxville McGhee Tyson to Indianapolis
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($87 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 7/10

10:05 pm-11:05 pm

1 stop25h 00m

Indianapolis

Fri 7/17

6:00 am-9:15 pm

1 stop15h 15m

$267
Quickest round-trip

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Wed 6/17

5:40 am-9:02 am

1 stop3h 22m

Indianapolis

Tue 6/23

6:00 am-9:38 am

1 stop3h 38m

$291

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Mon 6/22

7:19 pm-11:59 pm

1 stop4h 40m

Indianapolis

Wed 6/24

5:35 am-10:42 am

1 stop5h 07m

$328

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Tue 6/23

8:10 am-11:25 pm

2 stops15h 15m

Indianapolis

Tue 6/30

5:05 am-5:00 pm

1 stop11h 55m

$330

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Mon 8/3

7:41 pm-12:27 am

1 stop4h 46m

Indianapolis

Fri 8/7

6:00 am-11:11 am

1 stop5h 11m

$337

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 6/6

8:45 am-11:28 pm

1 stop14h 43m

Indianapolis

Wed 6/10

3:57 pm-12:46 pm

2 stops44h 49m

$385

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Thu 6/18

6:40 am-6:05 pm

2 stops11h 25m

Indianapolis

Thu 6/25

4:40 pm-10:30 pm

1 stop5h 50m

$398

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Thu 7/23

6:40 am-6:05 pm

2 stops11h 25m

Indianapolis

Sun 7/26

6:05 pm-9:20 pm

1 stop3h 15m

$398
Cheapest one-way
Quickest one-way

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Wed 7/1

5:40 am-10:18 am

1 stop4h 38m

$146

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sun 7/26

7:02 am-11:40 am

1 stop4h 38m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/23

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Indianapolis in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Indianapolis

What is the cheapest month to book a flight from Knoxville to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Indianapolis (average of $248). Flying from Knoxville to Indianapolis in March is currently the most expensive (average of $735). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated May 26, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,425 reviews

Crew

8.5

Overall

7.9

Comfort

7.8

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,425 reviews
Delta
7.9
Good
8,425 reviews

Crew

8.5

Overall

7.9

Comfort

7.8

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,629 reviews
Delta
7.9
Good
8,425 reviews

Crew

8.5

Overall

7.9

Comfort

7.8

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Indianapolis?

    Departing from Knoxville to Indianapolis will take you 3h 22m. The distance between Knoxville and Indianapolis is about 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Indianapolis round-trip?

    According to our current data, Delta ($218), and American Airlines ($228) offers the cheapest pricing from Knoxville to Indianapolis. You may be able to fly from Knoxville to Indianapolis for 48% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Knoxville to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Indianapolis.

  • Can I find deals for business class flights from Knoxville to Indianapolis?

    Yes. Cheapflights offers flight deals from Knoxville to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Indianapolis (average of $248). Flying from Knoxville to Indianapolis in March is currently the most expensive (average of $735). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Indianapolis

Discover the top 2 airlines that operate flights from Knoxville to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$278FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$288FlexibilityNo cancel feeOn-time71%

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