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$165+ Cheap flights from Knoxville to Indianapolis (TYS - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Jul 1 — Jul 81
Tue 7/1
Tue 7/8
1 adult, Economy
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Cheap flight deals from Knoxville to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 26, 2025.

Round-trip from

$196
(Mytrip)

One-way from

$165
(Mytrip)

Popular in

March

Cheapest in

July

Average price

$250
From Knoxville McGhee Tyson to Indianapolis
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One-way flight from Knoxville McGhee Tyson to Indianapolis
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Highest demand for flights based on searches. 9% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Indianapolis

Cheapest flights from Knoxville to Indianapolis
Explore the most affordable flight options available from Knoxville to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2025.

This Mytrip deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/247:44 pmTYS - IND
1 stop13h 06mAllegiant Air
Thu 7/319:28 pmIND - TYS
1 stop14h 30mAllegiant Air
Deal found 6/26$196
This Mytrip deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/237:10 amTYS - IND
1 stop8h 14mMultiple Airlines
Thu 7/319:28 pmIND - TYS
1 stop14h 30mMultiple Airlines
Deal found 6/25$200
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/31:06 pmTYS - IND
1 stop7h 34mAmerican Airlines
Tue 10/76:41 amIND - TYS
1 stop3h 43mAmerican Airlines
Deal found 6/25$219
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/275:45 amTYS - IND
1 stop3h 12mDelta
Mon 6/306:48 pmIND - TYS
1 stop5h 11mDelta
Deal found 6/26$259
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:00 amTYS - IND
2 stops8h 38mUnited Airlines
Wed 9/175:45 amIND - TYS
1 stop4h 43mUnited Airlines
Deal found 6/25$284

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2025.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.

Fly from

Knoxville

Fly to

Indianapolis

Route

Depart

Return

Price

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Thu 7/24

7:44 pm-8:50 am

1 stop13h 06m

Indianapolis

Thu 7/31

9:28 pm-11:58 am

1 stop14h 30m

$196

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Wed 7/23

7:10 am-3:24 pm

1 stop8h 14m

Indianapolis

Thu 7/31

9:28 pm-11:58 am

1 stop14h 30m

$200

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sun 8/24

9:15 am-2:46 pm

1 stop5h 31m

Indianapolis

Sun 8/31

8:48 am-3:35 pm

1 stop6h 47m

$219

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Wed 9/10

7:00 am-3:38 pm

2 stops8h 38m

Indianapolis

Wed 9/17

5:45 am-10:28 am

1 stop4h 43m

$284

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sun 7/6

5:45 am-8:57 am

1 stop3h 12m

Indianapolis

Sun 7/13

6:00 am-11:08 am

1 stop5h 08m

$399

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 7/12

6:00 am-11:36 pm

2 stops17h 36m

$165

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 7/12

7:30 am-7:41 pm

1 stop12h 11m

$185

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Mon 9/1

6:00 am-12:15 pm

1 stop6h 15m

$212

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/23

Best time to book a flight from Knoxville to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Indianapolis

What is the cheapest month to book a flight from Knoxville to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Indianapolis (average of $297). Flying from Knoxville to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IND?

Find hourly flight availability from Knoxville to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 26, 2025.

When flying from Knoxville to Indianapolis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 39% versus a flight at noon.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated June 26, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,838 reviews
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
712 reviews
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Indianapolis round-trip?

    According to our current data, Allegiant Air ($196), American Airlines ($219), and United Airlines ($284) offers the cheapest pricing from Knoxville to Indianapolis. You may be able to fly from Knoxville to Indianapolis for 29% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Knoxville to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Indianapolis.

  • Can I find deals for business class flights from Knoxville to Indianapolis?

    Yes. Cheapflights offers flight deals from Knoxville to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Indianapolis (average of $297). Flying from Knoxville to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Greenwood
Bloomington
Terre Haute
Noblesville
Muncie
Fishers
Anderson
Kokomo
Franklin
Plainfield
Carmel
Crawfordsville
Shelbyville
Speedway

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Top 3 airlines flying from Knoxville to Indianapolis

Discover the top 3 airlines that operate flights from Knoxville to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$258FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$269FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$278FlexibilityNo cancel feeOn-time69%

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