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Cheap flights from Columbus to Knoxville (TYS)

CMH — TYS
Oct 31 — Nov 71
Sat 10/31
Sat 11/7
1 adult, Economy
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Find flight deals from Columbus to Knoxville

Popular in

May

Cheapest in

February

Average price

$293
Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in October 2026
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Best time to book a flight from Columbus to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
Estimated round-trip price

Reviews of airlines servicing Knoxville

See what other customers who have flown with American Airlines from Columbus to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.0
Good
12,096 reviews

Entertainment

6.8

Boarding

7.4

Crew

7.9

Comfort

7.2

Food

6.4

Overall

7.0

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.0
Good
12,096 reviews
American Airlines
7.0
Good
12,096 reviews

Entertainment

6.8

Boarding

7.4

Crew

7.9

Comfort

7.2

Food

6.4

Overall

7.0

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

  • What airport do you fly into for flights to Knoxville from Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Columbus to Knoxville. You should not have trouble finding flights to McGhee Tyson from Columbus; the airport handles an average of 0 inbound flights from Columbus per day. You should also have plenty of airline options to choose from since 1 airline has flights to the Knoxville airport from Columbus. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • What is the cheapest airline to fly from Columbus to Knoxville round-trip?

    Currently priced at $238, American Airlines will fly you from Columbus to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is currently priced 42% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Knoxville that include hotel bookings?

    Yes. In addition to deals on Columbus to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Knoxville.

  • Can I find deals for business class flights from Columbus to Knoxville?

    Yes. Cheapflights offers flight deals from Columbus to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy

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Top airline flying from Columbus to Knoxville

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$238Average$400FlexibilityNo cancel feeOn-time71%

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