$98+ Cheap flights from Columbus to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:16 pm
CMH
- TYS
1 stop9h 45m
Multiple Airlines
Mon 6/112:55 pm
TYS
- CMH
2 stops28h 15m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 pm
CMH
- TYS
2 stops22h 40m
Multiple Airlines
Tue 6/304:45 pm
TYS
- CMH
1 stop27h 28m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:16 pm
CMH
- TYS
1 stop9h 34m
Multiple Airlines
Mon 6/157:22 pm
TYS
- CMH
2 stops21h 43m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$282
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:25 am
CMH
- TYS
1 stop6h 40m
Southwest
Wed 9/168:00 am
TYS
- CMH
1 stop4h 25m
Southwest
Deal found 5/6![Southwest logo]()
$299
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Wed 6/106:55 pm
TYS
- CMH
1 stop3h 05m
Southwest
Deal found 5/10![Southwest logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:58 pm
CMH
- TYS
1 stop25h 26m
Multiple Airlines
Mon 7/612:40 pm
TYS
- CMH
2 stops28h 24m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:05 pm
CMH
- TYS
1 stop4h 10m
Southwest
Thu 6/47:30 am
TYS
- CMH
1 stop4h 40m
Southwest
Deal found 5/6![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:20 pm
CMH
- TYS
1 stop4h 55m
Southwest
Sat 6/278:00 am
TYS
- CMH
1 stop3h 55m
Southwest
Deal found 5/8![Southwest logo]()
$318
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:16 pm
CMH
- TYS
1 stop9h 34m
Multiple Airlines
Mon 6/157:22 pm
TYS
- CMH
2 stops21h 43m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$282
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:50 am
CMH
- TYS
2 stops8h 05m
Southwest
Wed 9/168:00 am
TYS
- CMH
1 stop4h 25m
Southwest
Deal found 5/6![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:00 pm
CMH
- TYS
1 stop4h 09m
United Airlines
Thu 5/286:30 am
TYS
- CMH
1 stop6h 47m
United Airlines
Deal found 5/9![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Wed 6/106:55 pm
TYS
- CMH
1 stop3h 05m
Southwest
Deal found 5/10![Southwest logo]()
$305
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Tue 6/306:55 pm
TYS
- CMH
1 stop3h 05m
Southwest
Deal found 5/8![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
CMH
- TYS
1 stop8h 05m
Southwest
Mon 7/276:40 am
TYS
- CMH
1 stop5h 45m
Southwest
Deal found 5/8![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:55 am
CMH
- TYS
1 stop5h 05m
Southwest
Wed 8/58:00 am
TYS
- CMH
2 stops6h 55m
Southwest
Deal found 5/9![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:40 am
CMH
- TYS
2 stops11h 20m
Southwest
Sat 6/278:00 am
TYS
- CMH
1 stop3h 55m
Southwest
Deal found 5/7![Southwest logo]()
$329
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:50 pm
CMH
- TYS
1 stop5h 10m
Southwest
Mon 10/127:20 pm
TYS
- CMH
1 stop3h 20m
Southwest
Deal found 5/7![Southwest logo]()
$334
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated May 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:16 pm
CMH
- TYS
1 stop9h 45m
Multiple Airlines
Mon 6/112:55 pm
TYS
- CMH
2 stops28h 15m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:05 pm
CMH
- TYS
1 stop4h 10m
Southwest
Thu 6/47:30 am
TYS
- CMH
1 stop4h 40m
Southwest
Deal found 5/6![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:05 am
CMH
- TYS
1 stop3h 29m
Delta
Mon 6/87:15 am
TYS
- CMH
1 stop4h 12m
Delta
Deal found 5/6![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:01 pm
CMH
- TYS
1 stop7h 09m
American Airlines
Sat 6/137:59 pm
TYS
- CMH
1 stop3h 53m
American Airlines
Deal found 5/8![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Wed 6/106:55 pm
TYS
- CMH
1 stop3h 05m
Southwest
Deal found 5/10![Southwest logo]()
$305
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:20 pm
CMH
- TYS
1 stop4h 55m
Southwest
Sat 6/278:00 am
TYS
- CMH
1 stop3h 55m
Southwest
Deal found 5/8![Southwest logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 pm
CMH
- TYS
2 stops22h 40m
Multiple Airlines
Tue 6/304:45 pm
TYS
- CMH
1 stop27h 28m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:55 am
CMH
- TYS
2 stops10h 35m
Southwest
Tue 6/308:10 am
TYS
- CMH
2 stops9h 20m
Southwest
Deal found 5/8![Southwest logo]()
$334
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 pm
CMH
- TYS
2 stops27h 50m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:05 pm
CMH
- TYS
2 stops27h 56m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:00 pm
CMH
- TYS
2 stops27h 50m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:16 pm
CMH
- TYS
1 stop9h 45m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$135
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:01 pm
CMH
- TYS
1 stop5h 37m
American Airlines
Deal found 5/8![American Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:16 pm
CMH
- TYS
1 stop9h 34m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$151
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:01 pm
CMH
- TYS
1 stop5h 37m
American Airlines
Deal found 5/7![American Airlines logo]()
$156
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:00 pm
CMH
- TYS
1 stop5h 01m
Delta
Deal found 5/7![Delta logo]()
$161
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/8![Southwest logo]()
$169
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:25 am
CMH
- TYS
2 stops8h 20m
Southwest
Deal found 5/7![Southwest logo]()
$174
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.
Round-trip from | $235 (Kiwi.com) |
|---|---|
One-way from | $98 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $313 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Columbus to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 6/12
12:16 pm-9:50 pm
1 stop9h 34m
Knoxville McGhee Tyson
Mon 6/15
7:22 pm-5:05 pm
2 stops21h 43m
$282
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Wed 9/9
10:50 am-6:55 pm
2 stops8h 05m
Knoxville McGhee Tyson
Wed 9/16
8:00 am-12:25 pm
1 stop4h 25m
$304
Quickest round-trip
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Mon 6/8
5:35 pm-10:30 pm
1 stop4h 55m
Knoxville McGhee Tyson
Wed 6/10
6:55 pm-10:00 pm
1 stop3h 05m
$305
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 6/25
5:35 pm-10:30 pm
1 stop4h 55m
Knoxville McGhee Tyson
Tue 6/30
6:55 pm-10:00 pm
1 stop3h 05m
$318
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Wed 7/22
6:00 am-2:05 pm
1 stop8h 05m
Knoxville McGhee Tyson
Mon 7/27
6:40 am-12:25 pm
1 stop5h 45m
$318
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 7/30
6:55 am-12:00 pm
1 stop5h 05m
Knoxville McGhee Tyson
Wed 8/5
8:00 am-2:55 pm
2 stops6h 55m
$323
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Tue 6/23
5:40 am-5:00 pm
2 stops11h 20m
Knoxville McGhee Tyson
Sat 6/27
8:00 am-11:55 am
1 stop3h 55m
$329
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 10/9
3:50 pm-9:00 pm
1 stop5h 10m
Knoxville McGhee Tyson
Mon 10/12
7:20 pm-10:40 pm
1 stop3h 20m
$334
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Sun 5/24
8:00 pm-12:09 am
1 stop4h 09m
Knoxville McGhee Tyson
Thu 5/28
6:30 am-1:17 pm
1 stop6h 47m
$337
Cheapest one-way
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 6/11
6:00 pm-9:50 pm
2 stops27h 50m
$98
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
C01-TYS
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Knoxville
C01-TYS
CMH-TYS
What is the cheapest month to book a flight from Columbus to Knoxville?
Currently, June is the cheapest month in which you can book a flight from Columbus to Knoxville (average of $184). Flying from Columbus to Knoxville in January is currently the most expensive (average of $547). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Columbus to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 11, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Columbus to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
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Browse other Columbus and Knoxville flight options. Last updated on May 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Columbus to Knoxville
Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$390 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$218 | Average$506 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$235 | Average$422 | FlexibilityNo cancel fee | On-time69% |