$111+ Cheap flights from Knoxville (TYS) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Aug 11 — Aug 181
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Columbus with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Columbus
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to ColumbusExplore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:25 pm
TYS
- CMH
1 stop3h 30m
American Airlines
Thu 8/134:28 pm
CMH
- TYS
1 stop5h 06m
American Airlines
Deal found 7/9![American Airlines logo]()
$221
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:05 pm
TYS
- CMH
1 stop8h 55m
Southwest
Mon 8/107:10 am
CMH
- TYS
1 stop5h 10m
Southwest
Deal found 7/6![Southwest logo]()
$228
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:00 pm
TYS
- CMH
1 stop8h 10m
Southwest
Mon 9/77:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Deal found 7/7![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Sun 8/165:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Thu 8/135:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 am
TYS
- CMH
1 stop4h 05m
United Airlines
Sat 8/1512:30 pm
CMH
- TYS
1 stop4h 28m
United Airlines
Deal found 7/11![United Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Sun 8/95:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Wed 9/99:10 am
CMH
- TYS
2 stops10h 40m
Southwest
Deal found 7/11![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:50 am
TYS
- CMH
1 stop5h 35m
Southwest
Tue 8/257:00 am
CMH
- TYS
2 stops11h 55m
Southwest
Deal found 7/11![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:05 pm
TYS
- CMH
1 stop4h 50m
American Airlines
Sun 8/93:28 pm
CMH
- TYS
1 stop6h 22m
American Airlines
Deal found 7/8![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
TYS
- CMH
1 stop6h 06m
United Airlines
Tue 8/256:30 am
CMH
- TYS
1 stop6h 50m
United Airlines
Deal found 7/7![United Airlines logo]()
$291
Best flights from Knoxville to ColumbusDiscover carefully curated flight deals from Knoxville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 12, 2026.
Discover carefully curated flight deals from Knoxville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 12, 2026.
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:00 pm
TYS
- CMH
1 stop8h 10m
Southwest
Mon 9/77:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Deal found 7/7![Southwest logo]()
$251
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 am
TYS
- CMH
1 stop4h 05m
United Airlines
Sat 8/1512:30 pm
CMH
- TYS
1 stop4h 28m
United Airlines
Deal found 7/11![United Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Thu 8/135:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$270
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:40 am
TYS
- CMH
1 stop3h 17m
Delta
Sun 8/166:35 am
CMH
- TYS
1 stop3h 45m
Delta
Deal found 7/9![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Wed 9/99:10 am
CMH
- TYS
2 stops10h 40m
Southwest
Deal found 7/11![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
TYS
- CMH
1 stop6h 06m
United Airlines
Tue 8/257:59 pm
CMH
- TYS
1 stop4h 00m
United Airlines
Deal found 7/9![United Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:05 pm
TYS
- CMH
1 stop8h 55m
Southwest
Mon 8/107:20 am
CMH
- TYS
2 stops11h 15m
Southwest
Deal found 7/6![Southwest logo]()
$296
Last-minute flights from Knoxville to ColumbusDiscover last-minute flight deals from Knoxville to Columbus. Data last updated July 12, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Columbus. Data last updated July 12, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:05 pm
TYS
- CMH
1 stop8h 55m
Southwest
Mon 8/107:10 am
CMH
- TYS
1 stop5h 10m
Southwest
Deal found 7/6![Southwest logo]()
$228
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:25 pm
TYS
- CMH
1 stop3h 30m
American Airlines
Thu 8/134:28 pm
CMH
- TYS
1 stop5h 06m
American Airlines
Deal found 7/9![American Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Thu 8/135:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Sun 8/95:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:05 pm
TYS
- CMH
1 stop4h 50m
American Airlines
Sun 8/93:28 pm
CMH
- TYS
1 stop6h 22m
American Airlines
Deal found 7/8![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 am
TYS
- CMH
1 stop4h 05m
United Airlines
Sat 8/1512:30 pm
CMH
- TYS
1 stop4h 28m
United Airlines
Deal found 7/11![United Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Sun 8/165:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:50 am
TYS
- CMH
1 stop5h 35m
Southwest
Tue 8/257:00 am
CMH
- TYS
2 stops11h 55m
Southwest
Deal found 7/11![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
TYS
- CMH
1 stop6h 06m
United Airlines
Tue 8/256:30 am
CMH
- TYS
1 stop6h 50m
United Airlines
Deal found 7/7![United Airlines logo]()
$291
One-way flights from Knoxville to ColumbusSearch for one-way flight options from Knoxville to Columbus. Find affordable one-way fares based on user searches. Data last updated July 12, 2026.
Search for one-way flight options from Knoxville to Columbus. Find affordable one-way fares based on user searches. Data last updated July 12, 2026.
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:00 am
TYS
- CMH
1 stop4h 40m
United Airlines
Deal found 7/7![United Airlines logo]()
$111
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:10 am
TYS
- CMH
2 stops10h 05m
Southwest
Deal found 7/9![Southwest logo]()
$122
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:45 am
TYS
- CMH
1 stop4h 01m
United Airlines
Deal found 7/11![United Airlines logo]()
$133
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:50 am
TYS
- CMH
2 stops7h 50m
Southwest
Deal found 7/11![Southwest logo]()
$138
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:00 pm
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/7![Southwest logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:40 pm
TYS
- CMH
2 stops28h 19m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:40 pm
TYS
- CMH
1 stop6h 25m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:55 pm
TYS
- CMH
3 stops17h 47m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$195
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:45 pm
TYS
- CMH
1 stop6h 14m
United Airlines
Deal found 7/8![United Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:40 pm
TYS
- CMH
1 stop6h 25m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$226
Find flight deals from Knoxville to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 12, 2026.
Round-trip from | $221 (American Airlines) |
|---|---|
One-way from | $111 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 9/4
1:00 pm-9:10 pm
1 stop8h 10m
Columbus
Mon 9/7
7:30 am-1:25 pm
1 stop5h 55m
$251
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Sat 8/8
5:45 am-9:50 am
1 stop4h 05m
Columbus
Sat 8/15
12:30 pm-4:58 pm
1 stop4h 28m
$265
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 8/7
12:50 pm-7:05 pm
1 stop6h 15m
Columbus
Thu 8/13
5:44 pm-8:36 am
2 stops14h 52m
$270
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Thu 9/3
7:10 am-5:00 pm
2 stops9h 50m
Columbus
Wed 9/9
9:10 am-7:50 pm
2 stops10h 40m
$275
Quickest round-trip
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 8/14
5:40 am-8:57 am
1 stop3h 17m
Columbus
Sun 8/16
6:35 am-10:20 am
1 stop3h 45m
$279
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Sat 8/22
7:00 am-1:06 pm
1 stop6h 06m
Columbus
Tue 8/25
7:59 pm-11:59 pm
1 stop4h 00m
$291
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Thu 8/6
2:05 pm-11:00 pm
1 stop8h 55m
Columbus
Mon 8/10
7:20 am-6:35 pm
2 stops11h 15m
$296
Cheapest one-way
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 8/21
7:00 am-11:40 am
1 stop4h 40m
$111
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Sat 11/7
7:10 am-12:25 pm
1 stop5h 15m
$111
Quickest one-way
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Sat 9/12
5:45 am-9:46 am
1 stop4h 01m
$133
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
TYS-C01
TYS-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Columbus
TYS-C01
TYS-CMH
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated July 12, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Columbus
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Complete your trip
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Search flights from Knoxville to Columbus by cabin class
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Knoxville and Columbus flights
Browse other Knoxville and Columbus flight options. Last updated on July 12, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on July 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Columbus
Discover the top 2 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$336 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$367 | FlexibilityNo cancel fee | On-time71% |