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$111+ Cheap flights from Knoxville (TYS) to Columbus (CMH)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
may. 23 — may. 301
sáb. 5/23
sáb. 5/30
1 adult, Economy
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Cheap flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 23, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/235:02 pm
TYS
-
CMH
1 stop6h 21m
Multiple Airlines
dom. 6/286:00 pm
CMH
-
TYS
2 stops27h 50m
Multiple Airlines
Deal found 4/20$250
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/81:15 pm
TYS
-
CMH
1 stop6h 38m
Multiple Airlines
mar. 5/126:05 pm
CMH
-
TYS
2 stops16h 31m
Multiple Airlines
Deal found 4/23$264
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/117:33 pm
TYS
-
CMH
1 stop4h 57m
Delta
mié. 5/136:05 am
CMH
-
TYS
1 stop3h 29m
Delta
Deal found 4/20$270
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/64:25 pm
TYS
-
CMH
2 stops24h 45m
Multiple Airlines
dom. 5/106:00 am
CMH
-
TYS
1 stop14h 50m
Multiple Airlines
Deal found 4/21$297
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/181:15 pm
TYS
-
CMH
2 stops27h 55m
Multiple Airlines
lun. 5/251:37 pm
CMH
-
TYS
1 stop10h 00m
Multiple Airlines
Deal found 4/18$302
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/127:00 am
TYS
-
CMH
1 stop5h 30m
American Airlines
mié. 5/1311:59 am
CMH
-
TYS
1 stop3h 46m
American Airlines
Deal found 4/23$310
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/41:15 pm
TYS
-
CMH
1 stop23h 27m
Multiple Airlines
vie. 5/88:48 pm
CMH
-
TYS
2 stops14h 18m
Multiple Airlines
Deal found 4/19$334
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/64:25 pm
TYS
-
CMH
2 stops20h 17m
Multiple Airlines
jue. 5/77:20 pm
CMH
-
TYS
1 stop22h 10m
Multiple Airlines
Deal found 4/21$336
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/57:45 pm
TYS
-
CMH
1 stop3h 45m
Southwest
mar. 6/96:00 am
CMH
-
TYS
1 stop8h 05m
Southwest
Deal found 4/18$337

Find flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (CMH). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated abril 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$250
(Kiwi.com)

One-way from

$111
(Delta)

Popular in

April

Cheapest in

October

Average price

$494
Provider with most accurate pricing for Knoxville McGhee Tyson-Columbus flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Columbus flights.
Search Deals
From Knoxville McGhee Tyson to Columbus
Search Deals
One-way flight from Knoxville McGhee Tyson to Columbus
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 23, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

lun. 5/11

7:33 pm-12:30 am

1 stop4h 57m

Columbus

mié. 5/13

6:05 am-9:34 am

1 stop3h 29m

$270

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

lun. 5/18

1:15 pm-5:10 pm

2 stops27h 55m

Columbus

lun. 5/25

1:37 pm-11:37 pm

1 stop10h 00m

$302

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

mié. 5/6

4:25 pm-5:10 pm

2 stops24h 45m

Columbus

dom. 5/10

6:00 am-8:50 pm

1 stop14h 50m

$313

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

mié. 7/22

2:45 pm-9:15 pm

1 stop6h 30m

Columbus

sáb. 7/25

7:45 am-2:05 pm

1 stop6h 20m

$337

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

vie. 6/5

7:45 pm-11:30 pm

1 stop3h 45m

Columbus

mar. 6/9

6:00 am-2:05 pm

1 stop8h 05m

$337

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

vie. 7/10

6:00 am-12:19 pm

1 stop6h 19m

Columbus

lun. 7/13

4:38 pm-9:32 pm

1 stop4h 54m

$347

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

lun. 5/4

1:15 pm-12:42 pm

1 stop23h 27m

Columbus

vie. 5/8

6:00 am-12:25 pm

1 stop6h 25m

$352

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

mar. 5/12

5:50 pm-9:30 pm

1 stop3h 40m

Columbus

mié. 5/13

1:15 pm-7:40 pm

2 stops6h 25m

$404
Cheapest one-way
Quickest one-way

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

mié. 6/10

7:11 am-1:27 pm

1 stop6h 16m

$111

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

lun. 6/22

12:40 pm-5:05 pm

2 stops28h 25m

$112

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Columbus

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Columbus in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Columbus Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Columbus Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Columbus Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Columbus Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Columbus Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus Airport

How much does it cost to fly round-trip from Knoxville to Columbus Airport?

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated abril 23, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Knoxville to Columbus Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,438 reviews

Overall

7.9

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,438 reviews
Delta
7.9
Good
8,438 reviews

Overall

7.9

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,637 reviews
Delta
7.9
Good
8,438 reviews

Overall

7.9

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,659 reviews
Delta
7.9
Good
8,438 reviews

Overall

7.9

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Columbus. 3 airlines have flights from McGhee Tyson to Columbus on a regular basis. Booking flights from Knoxville McGhee Tyson to Columbus should not be difficult; the airport handles an average of 0 outbound flights to Columbus per day.

  • How long is the flight from Knoxville to Columbus Airport?

    For as low as $270, Delta can have you in Columbus Airport from Knoxville in 4h 57m. The distance from Knoxville to Columbus Airport is about 296 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Columbus Airport round-trip?

    Flying on Delta is currently your cheapest option to Columbus Airport, with prices starting at $218. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $228 and $294, respectively. You may be able to fly from Knoxville to Columbus Airport for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbus Airport?

Book flights to Columbus Airport if you plan to visit one of these locations
Westerville
Hilliard
Marysville
Reynoldsburg
Grove City
Logan
Lancaster
Gahanna

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Alternative routes for Knoxville to Columbus

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Columbus

Discover the top 3 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$258FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$294Average$361FlexibilityNo cancel feeOn-time69%

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