$108+ Cheap flights from Knoxville to Pittsburgh (TYS - PIT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PIT
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Pittsburgh with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Pittsburgh
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Cheapest flights from Knoxville to PittsburghExplore the most affordable flight options available from Knoxville to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Knoxville to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:45 am -
2 stops8h 52m
Sun 11/156:30 am -
1 stop15h 35m
Deal found 11/3![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:00 am -
1 stop10h 25m
Mon 12/77:59 pm -
1 stop17h 08m
Deal found 11/1![Multiple Airlines logo]()
$250
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:40 am -
1 stop4h 17m
Sat 12/56:10 am -
1 stop4h 17m
Deal found 11/2![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:45 pm -
1 stop6h 26m
Sat 12/57:00 am -
2 stops7h 53m
Deal found 11/2![United Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:37 pm -
1 stop25h 30m
Sun 11/156:30 am -
1 stop15h 35m
Deal found 11/3![Allegiant Air logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:45 am -
2 stops8h 52m
Mon 11/97:12 pm -
1 stop22h 06m
Deal found 10/30![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:00 am -
1 stop15h 31m
Mon 11/97:12 pm -
1 stop22h 06m
Deal found 10/30![Allegiant Air logo]()
$340
Best flights from Knoxville to PittsburghDiscover carefully curated flight deals from Knoxville to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Knoxville to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:45 pm -
1 stop6h 26m
Sat 12/57:00 am -
2 stops7h 53m
Deal found 11/2![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:40 pm -
1 stop4h 10m
Sun 11/2211:07 am -
1 stop4h 08m
Deal found 10/31![Delta logo]()
$414
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:05 am -
2 stops11h 45m
Mon 12/75:35 am -
2 stops11h 05m
Deal found 10/31![Southwest logo]()
$432
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:35 pm -
1 stop3h 55m
Mon 12/78:04 pm -
1 stop3h 55m
Deal found 11/1![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:05 am -
2 stops11h 45m
Sat 12/58:45 am -
2 stops11h 00m
Deal found 11/2![Southwest logo]()
$488
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:45 am -
1 stop6h 16m
Wed 11/186:12 am -
1 stop5h 18m
Deal found 10/30![United Airlines logo]()
$487
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:50 pm -
2 stops6h 50m
Wed 11/1812:20 pm -
2 stops7h 30m
Deal found 10/30![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:05 am -
2 stops9h 00m
Sat 11/215:45 pm -
1 stop3h 55m
Deal found 11/2![Southwest logo]()
$498
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:45 am -
1 stop6h 21m
Mon 11/236:30 am -
1 stop6h 43m
Deal found 11/3![United Airlines logo]()
$577
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:00 am -
2 stops14h 00m
Mon 12/75:35 am -
2 stops11h 05m
Deal found 11/1![Southwest logo]()
$568
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:25 pm -
1 stop4h 00m
Tue 11/174:00 pm -
1 stop4h 50m
Deal found 11/3![Southwest logo]()
$617
Last-minute flights from Knoxville to PittsburghDiscover last-minute flight deals from Knoxville to Pittsburgh. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Pittsburgh. Data last updated November 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:45 am -
2 stops8h 52m
Mon 11/97:12 pm -
1 stop22h 06m
Deal found 10/30![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:00 am -
1 stop15h 31m
Mon 11/97:12 pm -
1 stop22h 06m
Deal found 10/30![Allegiant Air logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:45 am -
2 stops8h 52m
Sun 11/156:30 am -
1 stop15h 35m
Deal found 11/3![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:37 pm -
1 stop25h 30m
Sun 11/156:30 am -
1 stop15h 35m
Deal found 11/3![Allegiant Air logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:00 am -
1 stop10h 25m
Mon 12/77:59 pm -
1 stop17h 08m
Deal found 11/1![Multiple Airlines logo]()
$250
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:40 am -
1 stop4h 17m
Sat 12/56:10 am -
1 stop4h 17m
Deal found 11/2![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:45 pm -
1 stop6h 26m
Sat 12/57:00 am -
2 stops7h 53m
Deal found 11/2![United Airlines logo]()
$278
One-way flights from Knoxville to PittsburghSearch for one-way flight options from Knoxville to Pittsburgh. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Knoxville to Pittsburgh. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:20 am -
1 stop14h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Allegiant Air logo]()
$108
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop4h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Delta logo]()
$137
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:05 am -
2 stops11h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 pm -
2 stops22h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:51 pm -
1 stop22h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:53 pm -
3 stops27h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:30 am -
1 stop10h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:50 pm -
2 stops44h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
2 stops11h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$234
Find flight deals from Knoxville to Pittsburgh
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Pittsburgh (PIT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Kiwi.com) |
One-way from | $108 (Kiwi.com) |
Popular in | February |
Cheapest in | December |
Average price | $441 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Knoxville to Pittsburgh that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Thu 12/17
8:20 am-10:58 pm
1 stop14h 38m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$108
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Tue 11/24
6:50 am-12:43 pm
1 stop5h 53m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Mon 11/23
5:40 am-10:02 am
1 stop4h 22m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Thu 12/17
7:05 am-6:10 pm
2 stops11h 05m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$148
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Tue 11/24
6:15 pm-5:07 pm
2 stops22h 52m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Thu 12/17
12:53 pm-4:37 pm
3 stops27h 44m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Sun 11/29
11:38 am-1:01 pm
2 stops49h 23m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$234
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Mon 11/23
7:42 pm-4:37 pm
3 stops20h 55m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Fri 11/20
8:10 am-9:20 pm
2 stops13h 10m
Pittsburgh
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
KnoxvillePittsburgh
TYS Knoxville McGhee Tyson - PIT Pittsburgh
TYSPIT
Knoxville McGhee Tyson
Tue 12/1
12:45 pm-7:11 pm
1 stop6h 26m
Pittsburgh
Sat 12/5
7:00 am-2:53 pm
2 stops7h 53m
$278
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Pittsburgh
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Pittsburgh in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Pittsburgh flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Pittsburgh flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Pittsburgh flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Pittsburgh flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Pittsburgh flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Pittsburgh
Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Knoxville with our price prediction graph.
TYS-PIT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Pittsburgh
Get insights into the airlines that provide service to Pittsburgh. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Pittsburgh. Reviews last updated November 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Pittsburgh to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Pittsburgh?
Book flights to Pittsburgh if you plan to visit one of these locationsMonroeville
Washington
Chester
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Knoxville and Pittsburgh flights
Browse other Knoxville and Pittsburgh flight options. Last updated on November 4, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Knoxville to Pittsburgh
Discover the top 4 airlines that operate flights from Knoxville to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$249 | Average$416 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$274 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$277 | Average$446 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$305 | Average$354 | FlexibilityNo cancel fee | On-time69% |