$134+ Cheap flights from Columbus to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Apr 23 — Apr 301
Round-trip
1 adult, Economy
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:27 am
CMH
- TYS
1 stop23h 09m
Multiple Airlines
Fri 4/106:20 pm
TYS
- CMH
1 stop14h 52m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:05 pm
CMH
- TYS
2 stops16h 31m
Multiple Airlines
Thu 5/73:55 pm
TYS
- CMH
1 stop6h 46m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:45 am
CMH
- TYS
1 stop26h 25m
Multiple Airlines
Thu 4/95:10 pm
TYS
- CMH
1 stop16h 31m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:08 am
CMH
- TYS
1 stop4h 28m
American Airlines
Fri 5/296:30 pm
TYS
- CMH
1 stop5h 12m
American Airlines
Deal found 3/23![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:50 am
CMH
- TYS
2 stops10h 50m
Southwest
Tue 4/285:50 pm
TYS
- CMH
1 stop3h 40m
Southwest
Deal found 3/22![Southwest logo]()
$296
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
CMH
- TYS
1 stop4h 42m
United Airlines
Fri 6/125:45 am
TYS
- CMH
1 stop4h 04m
United Airlines
Deal found 3/20![United Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:39 am
CMH
- TYS
1 stop8h 17m
United Airlines
Sat 5/25:55 pm
TYS
- CMH
1 stop5h 54m
United Airlines
Deal found 3/23![United Airlines logo]()
$313
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:27 am
CMH
- TYS
1 stop23h 09m
Multiple Airlines
Fri 4/106:20 pm
TYS
- CMH
1 stop14h 52m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$291
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:39 am
CMH
- TYS
1 stop8h 17m
United Airlines
Sat 5/25:55 pm
TYS
- CMH
1 stop5h 54m
United Airlines
Deal found 3/23![United Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:25 pm
CMH
- TYS
1 stop4h 55m
Southwest
Sat 4/187:45 am
TYS
- CMH
2 stops10h 00m
Southwest
Deal found 3/19![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:10 pm
CMH
- TYS
1 stop6h 24m
United Airlines
Sat 4/181:52 pm
TYS
- CMH
1 stop6h 38m
United Airlines
Deal found 3/19![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/191:05 pm
CMH
- TYS
2 stops9h 25m
Southwest
Mon 6/227:45 pm
TYS
- CMH
1 stop3h 45m
Southwest
Deal found 3/21![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:15 pm
CMH
- TYS
2 stops8h 00m
Southwest
Thu 5/76:35 am
TYS
- CMH
1 stop5h 25m
Southwest
Deal found 3/22![Southwest logo]()
$342
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:30 am
CMH
- TYS
1 stop4h 38m
United Airlines
Tue 4/2110:49 am
TYS
- CMH
2 stops11h 10m
United Airlines
Deal found 3/21![United Airlines logo]()
$366
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:55 pm
CMH
- TYS
1 stop5h 40m
Southwest
Sun 9/201:15 pm
TYS
- CMH
1 stop11h 00m
Southwest
Deal found 3/21![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:25 pm
CMH
- TYS
1 stop4h 55m
Southwest
Sun 4/197:35 pm
TYS
- CMH
1 stop3h 10m
Southwest
Deal found 3/19![Southwest logo]()
$357
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:25 am
CMH
- TYS
1 stop5h 15m
Southwest
Sat 4/187:45 am
TYS
- CMH
2 stops9h 15m
Southwest
Deal found 3/24![Southwest logo]()
$369
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated March 24, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated March 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:45 am
CMH
- TYS
1 stop26h 25m
Multiple Airlines
Thu 4/95:10 pm
TYS
- CMH
1 stop16h 31m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:27 am
CMH
- TYS
1 stop23h 09m
Multiple Airlines
Fri 4/106:20 pm
TYS
- CMH
1 stop14h 52m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$243
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:50 am
CMH
- TYS
2 stops10h 50m
Southwest
Tue 4/285:50 pm
TYS
- CMH
1 stop3h 40m
Southwest
Deal found 3/22![Southwest logo]()
$296
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:39 am
CMH
- TYS
1 stop8h 17m
United Airlines
Sat 5/25:55 pm
TYS
- CMH
1 stop5h 54m
United Airlines
Deal found 3/23![United Airlines logo]()
$313
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:40 pm
CMH
- TYS
1 stop27h 44m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 pm
CMH
- TYS
2 stops26h 48m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:15 am
CMH
- TYS
1 stop25h 21m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$148
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:25 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 3/24![Southwest logo]()
$169
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:40 am
CMH
- TYS
2 stops10h 40m
Southwest
Deal found 3/24![Southwest logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:08 pm
CMH
- TYS
2 stops21h 22m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:15 pm
CMH
- TYS
2 stops7h 05m
Southwest
Deal found 3/24![Southwest logo]()
$234
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:35 am
CMH
- TYS
2 stops7h 52m
United Airlines
Deal found 3/24![United Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:05 am
CMH
- TYS
1 stop5h 01m
Delta
Deal found 3/19![Delta logo]()
$243
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 24, 2026.
Round-trip from | $243 (Kiwi.com) |
|---|---|
One-way from | $134 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $333 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Columbus to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Tue 4/7
11:27 am-10:36 am
1 stop23h 09m
Knoxville McGhee Tyson
Fri 4/10
6:20 pm-9:12 am
1 stop14h 52m
$291
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Tue 4/28
11:39 am-7:56 pm
1 stop8h 17m
Knoxville McGhee Tyson
Sat 5/2
5:55 pm-11:49 pm
1 stop5h 54m
$313
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 4/17
4:10 pm-10:34 pm
1 stop6h 24m
Knoxville McGhee Tyson
Sat 4/18
1:52 pm-8:30 pm
1 stop6h 38m
$334
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 4/17
3:25 pm-8:20 pm
1 stop4h 55m
Knoxville McGhee Tyson
Sat 4/18
7:45 am-5:45 pm
2 stops10h 00m
$339
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 6/19
1:05 pm-10:30 pm
2 stops9h 25m
Knoxville McGhee Tyson
Mon 6/22
7:45 pm-11:30 pm
1 stop3h 45m
$342
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Mon 5/4
1:15 pm-9:15 pm
2 stops8h 00m
Knoxville McGhee Tyson
Thu 5/7
6:35 am-12:00 pm
1 stop5h 25m
$342
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 9/17
12:55 pm-6:35 pm
1 stop5h 40m
Knoxville McGhee Tyson
Sun 9/20
1:15 pm-12:15 am
1 stop11h 00m
$352
Quickest round-trip
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 4/17
3:25 pm-8:20 pm
1 stop4h 55m
Knoxville McGhee Tyson
Sun 4/19
7:35 pm-10:45 pm
1 stop3h 10m
$357
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Tue 4/14
5:30 am-10:08 am
1 stop4h 38m
Knoxville McGhee Tyson
Tue 4/21
10:49 am-9:59 pm
2 stops11h 10m
$366
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Sat 4/11
6:25 am-11:40 am
1 stop5h 15m
Knoxville McGhee Tyson
Sat 4/18
7:45 am-5:00 pm
2 stops9h 15m
$369
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
C01-TYS
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Knoxville
C01-TYS
CMH-TYS
What is the cheapest month to book a flight from Columbus to Knoxville?
Currently, June is the cheapest month in which you can book a flight from Columbus to Knoxville (average of $200). Flying from Columbus to Knoxville in November is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 24, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Columbus to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
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Columbus and Knoxville flights
Browse other Columbus and Knoxville flight options. Last updated on March 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Columbus to Knoxville
Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$390 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$218 | Average$467 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$235 | Average$462 | FlexibilityNo cancel fee | On-time69% |