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$97+ Cheap flights from Columbus to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Columbus to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$187
(Mytrip)

One-way from

$97
(Mytrip)

Popular in

September

Cheapest in

December

Average price

$268
From Columbus to Knoxville McGhee Tyson
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One-way flight from Columbus to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 4% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Columbus to Knoxville

Cheapest flights from Columbus to Knoxville
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:00 amCMH - TYS
1 stop11h 38mMultiple Airlines
Mon 8/251:22 pmTYS - CMH
1 stop8h 24mMultiple Airlines
Deal found 7/30$187
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:15 pmCMH - TYS
1 stop3h 48mAmerican Airlines
Mon 10/68:37 pmTYS - CMH
1 stop3h 20mAmerican Airlines
Deal found 7/31$219
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/187:45 pmCMH - TYS
1 stop4h 03mDelta
Mon 8/257:50 amTYS - CMH
1 stop5h 39mDelta
Deal found 7/31$224
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/314:19 pmCMH - TYS
1 stop6h 16mUnited Airlines
Mon 8/45:45 amTYS - CMH
1 stop4h 08mUnited Airlines
Deal found 7/31$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Columbus to Knoxville that are best for you.

Fly from

Columbus

Fly to

Knoxville

Route

Depart

Return

Price

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 8/22

6:00 am-5:38 pm

1 stop11h 38m

Knoxville McGhee Tyson

Mon 8/25

1:22 pm-9:46 pm

1 stop8h 24m

$187

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 9/12

7:45 pm-11:44 pm

1 stop3h 59m

Knoxville McGhee Tyson

Sat 9/20

5:45 am-9:54 am

1 stop4h 09m

$219

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 8/14

6:14 am-10:30 am

1 stop4h 16m

Knoxville McGhee Tyson

Sat 8/16

7:55 am-1:53 pm

1 stop5h 58m

$229

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 8/15

5:00 pm-11:27 pm

1 stop6h 27m

Knoxville McGhee Tyson

Tue 8/19

7:00 am-1:15 pm

1 stop6h 15m

$289

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 8/25

6:00 am-5:38 pm

1 stop11h 38m

$97

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 9/16

12:13 pm-4:49 pm

1 stop4h 36m

$126

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 8/25

7:56 pm-8:56 pm

1 stop25h 00m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Columbus to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Knoxville

What is the cheapest month to book a flight from Columbus to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Columbus to Knoxville (average of $294). Flying from Columbus to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to TYS?

Find hourly flight availability from Columbus to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

One of the essential ways to save on airfare from Columbus to Knoxville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 34% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 31, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Columbus to Knoxville. You should not have trouble finding flights to McGhee Tyson from Columbus; the airport handles an average of 0 inbound flights from Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Knoxville airport from Columbus. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • What are the cheapest airlines flying from Columbus to Knoxville round-trip?

    Currently priced at $219, American Airlines will fly you from Columbus to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $224 and $284, respectively. American Airlines is currently priced 27% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Knoxville that include hotel bookings?

    Yes. In addition to deals on Columbus to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Knoxville.

  • Can I find deals for business class flights from Columbus to Knoxville?

    Yes. Cheapflights offers flight deals from Columbus to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Columbus to Knoxville (average of $294). Flying from Columbus to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Columbus to Knoxville

Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$283FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$273FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$243Average$337FlexibilityNo cancel feeOn-time69%

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