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Knoxville

$194+ Cheap flights from Central America to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
SJO — TYS
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Find flight deals from Central America to Knoxville

Cheapest flights from Central America to Knoxville
Explore the most affordable flight options available from Central America to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/21:30 pmSJO - TYS
2 stops31h 25mMultiple Airlines
Fri 11/79:09 pmTYS - SJO
1 stop16h 16mMultiple Airlines
Deal found 10/20$326
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:25 pmSAL - TYS
1 stop25h 01mMultiple Airlines
Fri 12/59:23 amTYS - SAL
1 stop16h 50mMultiple Airlines
Deal found 10/20$340
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/310:10 amSAL - TYS
2 stops23h 23mMultiple Airlines
Fri 12/59:23 amTYS - SAL
1 stop16h 50mMultiple Airlines
Deal found 10/20$435
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:31 pmSJO - TYS
1 stop21h 32mMultiple Airlines
Mon 3/97:15 amTYS - SJO
2 stops18h 25mMultiple Airlines
Deal found 10/21$480
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:41 pmSAL - TYS
1 stop8h 58mAmerican Airlines
Mon 11/35:07 pmTYS - SAL
1 stop22h 21mAmerican Airlines
Deal found 10/20$484
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:55 amSAL - TYS
1 stop15h 49mUnited Airlines
Tue 12/25:45 amTYS - SAL
1 stop17h 06mUnited Airlines
Deal found 10/21$508
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:20 pmSAL - TYS
2 stops19h 30mAmerican Airlines
Fri 12/57:23 pmTYS - SAL
2 stops18h 03mAmerican Airlines
Deal found 10/20$523
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:20 pmSJO - TYS
1 stop8h 24mUnited Airlines
Mon 3/911:42 amTYS - SJO
1 stop11h 50mUnited Airlines
Deal found 10/20$523
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/23:31 pmSAL - TYS
1 stop24h 06mAmerican Airlines
Tue 11/45:07 pmTYS - SAL
1 stop22h 21mAmerican Airlines
Deal found 10/20$529
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:38 pmSJO - TYS
1 stop7h 19mAmerican Airlines
Mon 3/912:40 pmTYS - SJO
2 stops9h 50mAmerican Airlines
Deal found 10/20$546
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:45 amSAL - TYS
2 stops24h 48mMultiple Airlines
Mon 11/38:30 amTYS - SAL
2 stops27h 23mMultiple Airlines
Deal found 10/20$564

Cheap flight deals from Central America to Knoxville

Keep the following information in mind while searching for Central America to Knoxville flight deals. Data was last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$326
(Kiwi.com)

One-way from

$194
(Kiwi.com)
Provider with most accurate pricing for San Salvador El Salvador Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Salvador El Salvador Intl-Knoxville McGhee Tyson flights.
Search Deals
From Central America to Knoxville McGhee Tyson
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One-way flight from Central America to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Central America to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Central America to Knoxville that are best for you.

Fly from

Central America

Fly to

Knoxville

Route

Depart

Return

Price

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Sun 11/2

1:30 pm-6:27 pm

1 stop27h 57m

Knoxville McGhee Tyson

Fri 11/7

9:09 pm-12:25 pm

1 stop16h 16m

$333

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Thu 11/6

8:25 pm-10:26 pm

1 stop25h 01m

Knoxville McGhee Tyson

Fri 12/5

9:23 am-1:13 am

1 stop16h 50m

$340

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Tue 12/9

1:31 pm-12:03 pm

1 stop21h 32m

Knoxville McGhee Tyson

Mon 3/9

7:15 am-11:40 pm

2 stops18h 25m

$480

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Mon 11/3

7:45 am-1:01 pm

1 stop28h 16m

Knoxville McGhee Tyson

Fri 12/5

9:23 am-1:13 am

1 stop16h 50m

$515

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Thu 11/6

1:20 pm-9:50 am

2 stops19h 30m

Knoxville McGhee Tyson

Fri 12/5

7:23 pm-12:26 pm

2 stops18h 03m

$523

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Tue 12/9

2:20 pm-11:44 pm

1 stop8h 24m

Knoxville McGhee Tyson

Mon 3/9

11:42 am-9:32 pm

1 stop11h 50m

$523

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Sun 11/2

3:31 pm-4:37 pm

1 stop24h 06m

Knoxville McGhee Tyson

Tue 11/4

5:07 pm-2:28 pm

1 stop22h 21m

$529

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Sat 11/1

1:10 am-11:59 pm

1 stop21h 49m

Knoxville McGhee Tyson

Tue 11/4

4:25 pm-1:19 pm

1 stop21h 54m

$652

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Wed 11/26

7:35 am-10:09 pm

2 stops13h 34m

Knoxville McGhee Tyson

Fri 12/26

9:25 pm-1:32 am

1 stop29h 07m

$658

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Sat 12/6

1:26 pm-4:33 pm

1 stop26h 07m

Knoxville McGhee Tyson

Sat 12/13

6:28 pm-12:26 pm

2 stops18h 58m

$784

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 16 results
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Best time to book a flight from Central America to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Central America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Central America to Knoxville

What is the cheapest month to book a flight from Central America to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Central America to Knoxville (average of $108). Flying from Central America to Knoxville in August is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CA to TYS?

Find hourly flight availability from Central America to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

When flying from Central America to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 18% versus a flight in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 22, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Central America to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,981 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
Delta
7.9
Good
7,981 reviews
Delta
7.9
Good
7,981 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
American Airlines
7.2
Good
11,028 reviews
Delta
7.9
Good
7,981 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Related info for your journey

Find useful and relevant information for your journey from Central America to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Central America?

    For a flight from Central America to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Central America to Knoxville?

    There are many flights that can get you from Central America to Knoxville in 19h 30m. Fly via American Airlines to get the fastest option. The distance from Central America to Knoxville is about 1576 mi.

  • What are the most popular routes from Central America to Knoxville?

    The most popular flight routes from Central America to Knoxville are San José Juan Santamaria Intl - Knoxville McGhee Tyson, San Salvador El Salvador Intl - Knoxville McGhee Tyson and Tegucigalpa Toncontin - Knoxville McGhee Tyson.

  • Can I find deals for flights from Central America to Knoxville that include hotel bookings?

    Yes. In addition to deals on Central America to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Central America to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Central America to Knoxville.

  • Can I find deals for business class flights from Central America to Knoxville?

    Yes. Cheapflights offers flight deals from Central America to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Central America to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Central America to Knoxville (average of $108). Flying from Central America to Knoxville in August is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Central America to Knoxville

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Top 2 airlines flying from Central America to Knoxville

Discover the top 2 airlines that operate flights from Central America to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$447Average$677FlexibilityNo cancel feeOn-time71%
DeltaCheapest$530Average$774FlexibilityNo cancel feeOn-timeN/A

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