Knoxville

$379+ Cheap flights from Central America to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
SJO — TYS
Jan 11 — Jan 181
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Central America to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Central America to Knoxville

Cheapest flights from Central America to Knoxville
Explore the most affordable flight options available from Central America to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:39 pmSJO - TYS
1 stop20h 36mMultiple Airlines
Fri 1/26:00 amTYS - SJO
2 stops31h 25mMultiple Airlines
Deal found 12/10$623
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:34 amSJO - TYS
1 stop9h 54mAmerican Airlines
Fri 1/25:23 amTYS - SJO
1 stop18h 22mAmerican Airlines
Deal found 12/10$719
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:30 amSJO - TYS
1 stop16h 12mUnited Airlines
Sat 1/37:00 amTYS - SJO
1 stop14h 39mUnited Airlines
Deal found 12/10$780
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:00 amSJO - TYS
1 stop10h 14mDelta
Sat 1/34:31 pmTYS - SJO
1 stop6h 24mDelta
Deal found 12/10$836
This Air Canada deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:35 amSJO - TYS
2 stops14h 24mMultiple Airlines
Sat 1/311:00 amTYS - SJO
2 stops14h 05mMultiple Airlines
Deal found 12/10$2,615

Find flight deals from Central America to Knoxville

Keep the following information in mind while searching for Central America to Knoxville flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$379
(Kiwi.com)

One-way from

$162
(Kiwi.com)
Provider with most accurate pricing for San Salvador El Salvador Intl-Knoxville McGhee Tyson flight deals.
Provider most trusted by Cheapflights users for San Salvador El Salvador Intl-Knoxville McGhee Tyson flights.
From Central America to Knoxville McGhee Tyson
One-way flight from Central America to Knoxville McGhee Tyson

Cheapflights Fare Finder

 
Customize your flight search to find flights from Central America to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Central America to Knoxville that are best for you.

Fly from

Central America

Fly to

Knoxville

Route

Depart

Return

Price

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Mon 2/9

12:33 pm-12:10 pm

1 stop22h 37m

Knoxville McGhee Tyson

Sat 2/14

2:54 pm-11:40 am

1 stop21h 46m

$379

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Sun 1/25

1:30 pm-5:28 pm

2 stops26h 58m

Knoxville McGhee Tyson

Sun 2/1

9:29 am-12:22 pm

1 stop27h 53m

$386

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Mon 2/9

12:33 pm-12:10 pm

1 stop22h 37m

Knoxville McGhee Tyson

Sun 2/15

6:11 pm-11:40 am

2 stops42h 29m

$417

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Tue 4/7

11:13 am-11:19 pm

1 stop10h 06m

Knoxville McGhee Tyson

Tue 4/21

11:40 am-12:21 pm

1 stop26h 41m

$523

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Wed 1/21

4:40 pm-7:50 pm

1 stop26h 10m

Knoxville McGhee Tyson

Sun 1/25

6:59 am-9:19 pm

1 stop15h 20m

$528

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Tue 4/7

7:10 am-11:43 pm

2 stops14h 33m

Knoxville McGhee Tyson

Tue 4/21

11:08 am-6:25 pm

2 stops9h 17m

$536

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Wed 1/21

5:15 pm-10:57 am

2 stops16h 42m

Knoxville McGhee Tyson

Sun 1/25

7:20 pm-7:55 am

2 stops13h 35m

$1,183

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Sun 1/4

6:20 am-12:38 am

1 stop17h 18m

$553

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from Central America to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Central America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Central America to Knoxville

What is the cheapest month to book a flight from Central America to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Central America to Knoxville (average of $108). Flying from Central America to Knoxville in August is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CA to TYS?

Find hourly flight availability from Central America to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

When flying from Central America to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 22% versus a flight in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Central America to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Central America to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from Central America?

    For a flight from Central America to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Central America to Knoxville?

    There are many flights that can get you from Central America to Knoxville in 15h 49m. Fly via United Airlines or Avianca to get the fastest option. The distance from Central America to Knoxville is about 1576 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Central America to Knoxville?

  • Can I find deals for flights from Central America to Knoxville that include hotel bookings?

    Yes. In addition to deals on Central America to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Central America to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Central America to Knoxville.

  • Can I find deals for business class flights from Central America to Knoxville?

    Yes. Cheapflights offers flight deals from Central America to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Central America to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Central America to Knoxville (average of $108). Flying from Central America to Knoxville in August is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Central America to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Central America to Knoxville

Discover the top 3 airlines that operate flights from Central America to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$447Average$705FlexibilityNo cancel feeOn-time71%
DeltaCheapest$530Average$774FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$631Average$738FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.