$112+ Cheap flights from Buffalo to Knoxville (BUF - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — TYS
Apr 28 — May 51
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Buffalo to KnoxvilleExplore the most affordable flight options available from Buffalo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.
Explore the most affordable flight options available from Buffalo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:52 pm
BUF
- TYS
2 stops46h 06m
Multiple Airlines
Mon 6/87:27 pm
TYS
- BUF
1 stop23h 40m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
BUF
- TYS
1 stop5h 31m
American Airlines
Wed 4/295:11 pm
TYS
- BUF
1 stop6h 48m
American Airlines
Deal found 3/25![American Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:52 pm
BUF
- TYS
1 stop22h 29m
Multiple Airlines
Sat 6/66:00 am
TYS
- BUF
1 stop12h 59m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:00 pm
BUF
- TYS
1 stop4h 50m
Southwest
Sat 5/166:40 am
TYS
- BUF
1 stop7h 35m
Southwest
Deal found 3/26![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:25 am
BUF
- TYS
1 stop3h 56m
Delta
Mon 5/117:33 pm
TYS
- BUF
1 stop4h 26m
Delta
Deal found 3/25![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:05 am
BUF
- TYS
2 stops11h 05m
Southwest
Sat 6/61:35 pm
TYS
- BUF
2 stops9h 35m
Southwest
Deal found 3/26![Southwest logo]()
$305
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:02 pm
BUF
- TYS
1 stop4h 32m
United Airlines
Sat 4/187:20 pm
TYS
- BUF
1 stop4h 30m
United Airlines
Deal found 3/25![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
BUF
- TYS
1 stop5h 31m
American Airlines
Tue 4/286:38 pm
TYS
- BUF
1 stop5h 11m
American Airlines
Deal found 3/27![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:53 pm
BUF
- TYS
1 stop5h 27m
Delta
Thu 4/307:00 pm
TYS
- BUF
1 stop4h 37m
Delta
Deal found 3/27![Delta logo]()
$311
Best flights from Buffalo to KnoxvilleDiscover carefully curated flight deals from Buffalo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 29, 2026.
Discover carefully curated flight deals from Buffalo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 29, 2026.
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:25 am
BUF
- TYS
1 stop3h 56m
Delta
Mon 5/117:33 pm
TYS
- BUF
1 stop4h 26m
Delta
Deal found 3/25![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 am
BUF
- TYS
2 stops11h 05m
Southwest
Sat 5/166:40 am
TYS
- BUF
1 stop7h 35m
Southwest
Deal found 3/26![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:02 pm
BUF
- TYS
1 stop4h 32m
United Airlines
Sat 4/187:20 pm
TYS
- BUF
1 stop4h 30m
United Airlines
Deal found 3/25![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:53 pm
BUF
- TYS
1 stop5h 27m
Delta
Thu 4/307:00 pm
TYS
- BUF
1 stop4h 37m
Delta
Deal found 3/27![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:05 am
BUF
- TYS
2 stops11h 05m
Southwest
Wed 4/297:05 am
TYS
- BUF
2 stops7h 30m
Southwest
Deal found 3/25![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:55 pm
BUF
- TYS
1 stop4h 53m
Delta
Mon 6/87:43 pm
TYS
- BUF
1 stop4h 16m
Delta
Deal found 3/28![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:52 pm
BUF
- TYS
1 stop6h 43m
United Airlines
Mon 7/65:45 am
TYS
- BUF
1 stop4h 06m
United Airlines
Deal found 3/28![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:05 am
BUF
- TYS
2 stops9h 40m
Southwest
Sun 8/27:05 am
TYS
- BUF
2 stops10h 15m
Southwest
Deal found 3/24![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
BUF
- TYS
1 stop5h 17m
Delta
Sun 4/195:40 am
TYS
- BUF
1 stop5h 21m
Delta
Deal found 3/26![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:25 am
BUF
- TYS
1 stop8h 30m
Southwest
Sun 8/168:30 am
TYS
- BUF
1 stop8h 35m
Southwest
Deal found 3/26![Southwest logo]()
$368
Last-minute flights from Buffalo to KnoxvilleDiscover last-minute flight deals from Buffalo to Knoxville. Data last updated March 29, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Knoxville. Data last updated March 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:02 pm
BUF
- TYS
1 stop4h 32m
United Airlines
Sat 4/187:20 pm
TYS
- BUF
1 stop4h 30m
United Airlines
Deal found 3/25![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
BUF
- TYS
1 stop5h 17m
Delta
Sun 4/195:40 am
TYS
- BUF
1 stop5h 21m
Delta
Deal found 3/26![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
BUF
- TYS
1 stop5h 31m
American Airlines
Wed 4/295:11 pm
TYS
- BUF
1 stop6h 48m
American Airlines
Deal found 3/25![American Airlines logo]()
$233
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
BUF
- TYS
1 stop5h 31m
American Airlines
Tue 4/286:38 pm
TYS
- BUF
1 stop5h 11m
American Airlines
Deal found 3/27![American Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:05 am
BUF
- TYS
2 stops11h 05m
Southwest
Wed 4/297:05 am
TYS
- BUF
2 stops7h 30m
Southwest
Deal found 3/25![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:56 pm
BUF
- TYS
2 stops25h 45m
Multiple Airlines
Mon 4/271:15 pm
TYS
- BUF
1 stop6h 11m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:05 am
BUF
- TYS
2 stops11h 05m
Southwest
Tue 4/287:05 am
TYS
- BUF
2 stops11h 10m
Southwest
Deal found 3/27![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:53 pm
BUF
- TYS
1 stop5h 27m
Delta
Thu 4/307:00 pm
TYS
- BUF
1 stop4h 37m
Delta
Deal found 3/27![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:28 pm
BUF
- TYS
1 stop4h 27m
American Airlines
Thu 4/305:00 am
TYS
- BUF
2 stops6h 58m
American Airlines
Deal found 3/27![American Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:56 pm
BUF
- TYS
2 stops20h 40m
Multiple Airlines
Mon 5/41:15 pm
TYS
- BUF
1 stop6h 11m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$347
One-way flights from Buffalo to KnoxvilleSearch for one-way flight options from Buffalo to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 29, 2026.
Search for one-way flight options from Buffalo to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:41 pm
BUF
- TYS
2 stops27h 00m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$112
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:42 pm
BUF
- TYS
1 stop4h 08m
American Airlines
Deal found 3/25![American Airlines logo]()
$140
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
BUF
- TYS
1 stop4h 54m
Delta
Deal found 3/28![Delta logo]()
$156
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:35 pm
BUF
- TYS
1 stop4h 16m
American Airlines
Deal found 3/27![American Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:05 am
BUF
- TYS
1 stop4h 16m
Delta
Deal found 3/24![Delta logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2512:29 pm
BUF
- TYS
2 stops31h 52m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:52 pm
BUF
- TYS
3 stops45h 29m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
BUF
- TYS
2 stops10h 59m
United Airlines
Deal found 3/24![United Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:08 pm
BUF
- TYS
1 stop5h 49m
Delta
Deal found 3/24![Delta logo]()
$304
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:29 am
BUF
- TYS
2 stops9h 00m
American Airlines
Deal found 3/24![American Airlines logo]()
$309
Find flight deals from Buffalo to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $223 (Kiwi.com) |
One-way from | $112 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $283 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Buffalo to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Fri 5/8
6:25 am-10:21 am
1 stop3h 56m
Knoxville McGhee Tyson
Mon 5/11
7:33 pm-11:59 pm
1 stop4h 26m
$302
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Tue 5/12
6:05 am-5:10 pm
2 stops11h 05m
Knoxville McGhee Tyson
Sat 5/16
6:40 am-2:15 pm
1 stop7h 35m
$306
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Mon 4/13
6:02 pm-10:34 pm
1 stop4h 32m
Knoxville McGhee Tyson
Sat 4/18
7:20 pm-11:50 pm
1 stop4h 30m
$309
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Mon 4/27
3:53 pm-9:20 pm
1 stop5h 27m
Knoxville McGhee Tyson
Thu 4/30
7:00 pm-11:37 pm
1 stop4h 37m
$311
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Mon 6/1
4:55 pm-9:48 pm
1 stop4h 53m
Knoxville McGhee Tyson
Mon 6/8
7:43 pm-11:59 pm
1 stop4h 16m
$311
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Wed 4/22
6:05 am-5:10 pm
2 stops11h 05m
Knoxville McGhee Tyson
Wed 4/29
7:05 am-2:35 pm
2 stops7h 30m
$327
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Wed 4/15
6:00 am-11:17 am
1 stop5h 17m
Knoxville McGhee Tyson
Sun 4/19
5:40 am-11:01 am
1 stop5h 21m
$339
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Thu 7/2
5:52 pm-12:35 am
1 stop6h 43m
Knoxville McGhee Tyson
Mon 7/6
5:45 am-9:51 am
1 stop4h 06m
$364
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Fri 7/31
6:05 am-3:45 pm
2 stops9h 40m
Knoxville McGhee Tyson
Sun 8/2
7:05 am-5:20 pm
2 stops10h 15m
$367
BuffaloKnoxville
BUF - TYS
BUFTYS
Buffalo
Thu 8/13
11:25 am-7:55 pm
1 stop8h 30m
Knoxville McGhee Tyson
Sun 8/16
8:30 am-5:05 pm
1 stop8h 35m
$368
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Buffalo with our price prediction graph.
BUF-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Knoxville
What is the cheapest month to book a flight from Buffalo to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Buffalo to Knoxville (average of $137). Flying from Buffalo to Knoxville in February is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 29, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Buffalo to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
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Crossville
Corbin
Morristown
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Alcoa
Murphy
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Top 3 airlines flying from Buffalo to Knoxville
Discover the top 3 airlines that operate flights from Buffalo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$328 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$338 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$453 | FlexibilityNo cancel fee | On-time69% |