Key West

$165+ Cheap flights from Panama City, FL to Key West (ECP - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Jun 17 — Jun 241
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Cheap flight deals from Panama City to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$329
(Delta)

One-way from

$165
(Delta)

Popular in

March

Cheapest in

July

Average price

$458
From Panama City NW Florida Beaches to Key West
One-way flight from Panama City NW Florida Beaches to Key West
Highest demand for flights based on searches. 14% potential increase in price ($93 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in June 2025

Find flight deals from Panama City to Key West

Cheapest flights from Panama City to Key West
Explore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/71:04 pmECP - EYW
1 stop5h 45mDelta
Sat 8/166:22 pmEYW - ECP
1 stop5h 44mDelta
Deal found 6/11$329
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/165:30 amECP - EYW
1 stop5h 30mAmerican Airlines
Tue 7/2211:18 amEYW - ECP
2 stops8h 07mAmerican Airlines
Deal found 6/9$334
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:30 amECP - EYW
2 stops34h 35mUnited Airlines
Tue 10/78:45 amEYW - ECP
2 stops38h 03mUnited Airlines
Deal found 6/9$568

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama City to Key West that are best for you.

Fly from

Panama City

Fly to

Key West

Route

Depart

Return

Price

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 8/7

11:39 am-5:32 pm

1 stop4h 53m

Key West

Mon 8/18

6:22 pm-11:06 pm

1 stop5h 44m

$329

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Wed 7/16

5:30 am-12:00 pm

1 stop5h 30m

Key West

Tue 7/22

11:18 am-6:25 pm

2 stops8h 07m

$334

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 9/29

6:30 am-6:05 pm

2 stops34h 35m

Key West

Tue 10/7

8:45 am-9:48 pm

2 stops38h 03m

$568

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sun 8/3

7:25 am-1:08 pm

1 stop4h 43m

$165

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 10/23

6:30 am-6:05 pm

2 stops34h 35m

$295

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sun 8/3

8:24 am-7:21 pm

2 stops9h 57m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Panama City to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Key West

What is the cheapest month to book a flight from Panama City, Florida to Key West?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Key West (average of $328). Flying from Panama City, Florida to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Panama City to Key West. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
8.0
Very good
8.0
Very good

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
8.0
Very good

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
8.0
Very good

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Panama City, Florida to Key West round-trip?

    Delta, at $329, was found to be the cheapest airline from Panama City, Florida to Key West.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Panama City, Florida to Key West for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Key West that include hotel bookings?

    Yes. In addition to deals on Panama City to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Key West.

  • Can I find deals for business class flights from Panama City to Key West?

    Yes. Cheapflights offers flight deals from Panama City to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Key West?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Key West (average of $328). Flying from Panama City, Florida to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Key West

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Panama City to Key West

Discover the top 2 airlines that operate flights from Panama City to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$338Average$553FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$358Average$468FlexibilityNo cancel feeOn-time71%

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