$248+ Cheap flights from Panama City, FL to Key West (ECP - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Mar 2 — Mar 91
1 adult, Economy
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Find cheap flights from Panama City to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Key West
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to Key WestExplore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 31, 2026.
Explore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 31, 2026.
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Thu 6/182:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Thu 6/182:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:05 am
ECP
- EYW
1 stop5h 39m
Delta
Wed 5/137:00 am
EYW
- ECP
1 stop4h 14m
Delta
Deal found 1/29![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:05 pm
ECP
- EYW
1 stop4h 37m
Delta
Mon 3/96:25 pm
EYW
- ECP
1 stop5h 39m
Delta
Deal found 1/30![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Tue 6/167:00 am
EYW
- ECP
1 stop6h 38m
Delta
Deal found 1/29![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:00 am
ECP
- EYW
2 stops11h 21m
American Airlines
Wed 6/171:02 pm
EYW
- ECP
1 stop6h 21m
American Airlines
Deal found 1/29![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:00 am
ECP
- EYW
2 stops11h 21m
American Airlines
Thu 6/184:45 pm
EYW
- ECP
1 stop7h 56m
American Airlines
Deal found 1/29![American Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Wed 6/172:35 pm
EYW
- ECP
1 stop5h 01m
Delta
Deal found 1/29![Delta logo]()
$393
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Wed 6/177:00 am
EYW
- ECP
1 stop6h 38m
Delta
Deal found 1/29![Delta logo]()
$403
Best flights from Panama City to Key WestDiscover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 31, 2026.
Discover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 31, 2026.
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Thu 6/182:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:00 am
ECP
- EYW
2 stops11h 21m
American Airlines
Tue 6/167:33 pm
EYW
- ECP
1 stop5h 08m
American Airlines
Deal found 1/29![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Thu 6/182:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Thu 6/182:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:05 am
ECP
- EYW
1 stop5h 39m
Delta
Wed 5/137:00 am
EYW
- ECP
1 stop4h 14m
Delta
Deal found 1/29![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:05 pm
ECP
- EYW
1 stop4h 37m
Delta
Mon 3/96:25 pm
EYW
- ECP
1 stop5h 39m
Delta
Deal found 1/30![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Tue 6/167:00 am
EYW
- ECP
1 stop6h 38m
Delta
Deal found 1/29![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:30 pm
ECP
- EYW
1 stop5h 14m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Fri 6/192:35 pm
EYW
- ECP
1 stop6h 01m
Delta
Deal found 1/29![Delta logo]()
$383
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:47 pm
ECP
- EYW
1 stop3h 57m
Delta
Wed 6/172:35 pm
EYW
- ECP
1 stop5h 01m
Delta
Deal found 1/29![Delta logo]()
$403
Last-minute flights from Panama City to Key WestDiscover last-minute flight deals from Panama City to Key West. Data last updated January 31, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Key West. Data last updated January 31, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:00 am
ECP
- EYW
1 stop4h 25m
Delta
Tue 2/106:06 pm
EYW
- ECP
1 stop5h 34m
Delta
Deal found 1/29![Delta logo]()
$434
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:00 am
ECP
- EYW
1 stop6h 48m
Delta
Thu 2/127:10 am
EYW
- ECP
1 stop7h 10m
Delta
Deal found 1/29![Delta logo]()
$478
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/312:03 pm
ECP
- EYW
1 stop4h 58m
American Airlines
Wed 2/117:08 am
EYW
- ECP
1 stop5h 25m
American Airlines
Deal found 1/29![American Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:00 am
ECP
- EYW
1 stop4h 25m
Delta
Tue 2/106:06 pm
EYW
- ECP
1 stop5h 34m
Delta
Deal found 1/29![Delta logo]()
$450
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:00 am
ECP
- EYW
1 stop4h 25m
Delta
Thu 2/127:10 am
EYW
- ECP
1 stop7h 10m
Delta
Deal found 1/29![Delta logo]()
$494
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 am
ECP
- EYW
1 stop6h 48m
Delta
Mon 2/97:10 am
EYW
- ECP
1 stop4h 58m
Delta
Deal found 1/29![Delta logo]()
$507
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/67:20 am
ECP
- EYW
1 stop5h 28m
Delta
Tue 2/106:06 pm
EYW
- ECP
1 stop5h 34m
Delta
Deal found 1/29![Delta logo]()
$483
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:00 am
ECP
- EYW
1 stop6h 48m
Delta
Mon 2/97:10 am
EYW
- ECP
1 stop4h 58m
Delta
Deal found 1/29![Delta logo]()
$527
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/612:03 pm
ECP
- EYW
1 stop4h 58m
American Airlines
Wed 2/117:08 am
EYW
- ECP
1 stop5h 25m
American Airlines
Deal found 1/29![American Airlines logo]()
$536
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/612:03 pm
ECP
- EYW
1 stop4h 58m
American Airlines
Tue 2/171:55 pm
EYW
- ECP
2 stops9h 22m
American Airlines
Deal found 1/30![American Airlines logo]()
$541
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/77:20 am
ECP
- EYW
1 stop5h 28m
Delta
Mon 2/97:10 am
EYW
- ECP
1 stop4h 58m
Delta
Deal found 1/29![Delta logo]()
$463
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:05 pm
ECP
- EYW
1 stop4h 37m
Delta
Fri 3/65:56 pm
EYW
- ECP
1 stop5h 43m
Delta
Deal found 1/31![Delta logo]()
$513
One-way flights from Panama City to Key WestSearch for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated January 31, 2026.
Search for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated January 31, 2026.
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:49 am
ECP
- EYW
1 stop6h 55m
Delta
Deal found 1/30![Delta logo]()
$248
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:48 am
ECP
- EYW
2 stops11h 09m
American Airlines
Deal found 1/30![American Airlines logo]()
$253
Find flight deals from Panama City to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (Delta) |
One-way from | $248 (Delta) |
Popular in | March |
Cheapest in | October |
Average price | $515 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 31, 2026.
Use the filters below to find and compare flights from Panama City to Key West that are best for you.
Fly from
Panama City
Fly to
Key West
Route
Depart
Return
Price
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Tue 6/9
1:30 pm-7:44 pm
1 stop5h 14m
Key West
Thu 6/18
2:35 pm-7:36 pm
1 stop6h 01m
$317
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Thu 6/11
1:30 pm-7:44 pm
1 stop5h 14m
Key West
Thu 6/18
2:35 pm-7:36 pm
1 stop6h 01m
$327
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Mon 6/8
2:47 pm-7:44 pm
1 stop3h 57m
Key West
Thu 6/18
2:35 pm-7:36 pm
1 stop6h 01m
$327
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 5/6
7:05 am-1:44 pm
1 stop5h 39m
Key West
Wed 5/13
7:00 am-10:14 am
1 stop4h 14m
$333
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 3/6
2:05 pm-7:42 pm
1 stop4h 37m
Key West
Mon 3/9
6:25 pm-11:04 pm
1 stop5h 39m
$343
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Thu 6/11
2:47 pm-7:44 pm
1 stop3h 57m
Key West
Tue 6/16
7:00 am-12:38 pm
1 stop6h 38m
$343
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Tue 6/9
1:30 pm-7:44 pm
1 stop5h 14m
Key West
Fri 6/19
2:35 pm-7:36 pm
1 stop6h 01m
$357
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Mon 6/8
2:47 pm-7:44 pm
1 stop3h 57m
Key West
Fri 6/19
2:35 pm-7:36 pm
1 stop6h 01m
$367
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 6/12
1:30 pm-7:44 pm
1 stop5h 14m
Key West
Fri 6/19
2:35 pm-7:36 pm
1 stop6h 01m
$367
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 6/10
7:00 am-7:21 pm
2 stops11h 21m
Key West
Tue 6/16
7:33 pm-11:41 pm
1 stop5h 08m
$372
Showing 1-10 of 14 results
Compare providers for flights from Panama City to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Key West in January.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Panama City with our price prediction graph.
ECP-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Key West
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated January 31, 2026.
Read through reviews of airlines operating flights from Panama City to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Panama City to Key West
Discover the top 2 airlines that operate flights from Panama City to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$332 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$488 | FlexibilityNo cancel fee | On-timeN/A |