$125+ Cheap flights from Myrtle Beach to Key West (MYR - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
Jun 4 — Jun 111
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Key West
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Cheapest flights from Myrtle Beach to Key WestExplore the most affordable flight options available from Myrtle Beach to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
Explore the most affordable flight options available from Myrtle Beach to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:53 pm
MYR
- EYW
1 stop19h 34m
Multiple Airlines
Thu 5/219:24 pm
EYW
- MYR
1 stop11h 41m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:45 pm
MYR
- EYW
2 stops44h 56m
Multiple Airlines
Tue 7/211:14 pm
EYW
- MYR
1 stop22h 25m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MYR
- EYW
1 stop4h 53m
Delta
Tue 6/96:24 pm
EYW
- MYR
1 stop5h 35m
Delta
Deal found 5/3![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:45 pm
MYR
- EYW
1 stop7h 02m
American Airlines
Sat 11/74:53 pm
EYW
- MYR
1 stop7h 02m
American Airlines
Deal found 5/4![American Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 am
MYR
- EYW
2 stops6h 50m
American Airlines
Sat 8/297:15 pm
EYW
- MYR
1 stop4h 35m
American Airlines
Deal found 4/30![American Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
MYR
- EYW
1 stop15h 29m
Multiple Airlines
Fri 6/1912:07 pm
EYW
- MYR
2 stops32h 04m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm
MYR
- EYW
2 stops17h 12m
Multiple Airlines
Sun 8/306:21 pm
EYW
- MYR
1 stop14h 44m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
MYR
- EYW
1 stop15h 29m
Breeze Airways
Fri 6/191:11 pm
EYW
- MYR
1 stop22h 28m
Breeze Airways
Deal found 4/30![Breeze Airways logo]()
$336
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:43 am
MYR
- EYW
1 stop5h 40m
Delta
Wed 5/206:19 pm
EYW
- MYR
1 stop5h 39m
Delta
Deal found 4/30![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:12 pm
MYR
- EYW
1 stop18h 24m
Breeze Airways
Sat 11/710:04 am
EYW
- MYR
2 stops10h 00m
Breeze Airways
Deal found 5/1![Breeze Airways logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:47 pm
MYR
- EYW
2 stops17h 11m
Multiple Airlines
Wed 6/311:46 am
EYW
- MYR
1 stop27h 28m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$346
Best flights from Myrtle Beach to Key WestDiscover carefully curated flight deals from Myrtle Beach to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
Discover carefully curated flight deals from Myrtle Beach to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:53 pm
MYR
- EYW
1 stop19h 34m
Multiple Airlines
Thu 5/219:24 pm
EYW
- MYR
1 stop11h 41m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:43 am
MYR
- EYW
1 stop5h 40m
Delta
Mon 5/186:19 pm
EYW
- MYR
1 stop5h 39m
Delta
Deal found 5/3![Delta logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:53 pm
MYR
- EYW
3 stops18h 34m
Breeze Airways
Sun 5/3111:04 am
EYW
- MYR
1 stop24h 35m
Breeze Airways
Deal found 5/2![Breeze Airways logo]()
$692
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:53 pm
MYR
- EYW
1 stop19h 34m
Multiple Airlines
Sun 6/79:16 pm
EYW
- MYR
2 stops22h 41m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$441
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:43 am
MYR
- EYW
1 stop5h 40m
Delta
Tue 6/26:19 pm
EYW
- MYR
1 stop5h 39m
Delta
Deal found 5/3![Delta logo]()
$479
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
MYR
- EYW
1 stop4h 53m
Delta
Sat 5/167:30 am
EYW
- MYR
1 stop5h 10m
Delta
Deal found 5/4![Delta logo]()
$504
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:30 pm
MYR
- EYW
1 stop6h 19m
Delta
Wed 6/36:19 pm
EYW
- MYR
1 stop5h 39m
Delta
Deal found 4/30![Delta logo]()
$547
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
MYR
- EYW
1 stop6h 27m
Delta
Sat 5/236:19 pm
EYW
- MYR
1 stop5h 40m
Delta
Deal found 5/4![Delta logo]()
$609
Last-minute flights from Myrtle Beach to Key WestDiscover last-minute flight deals from Myrtle Beach to Key West. Data last updated May 5, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Key West. Data last updated May 5, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:43 am
MYR
- EYW
1 stop5h 40m
Delta
Wed 5/206:19 pm
EYW
- MYR
1 stop5h 39m
Delta
Deal found 4/30![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:53 pm
MYR
- EYW
1 stop19h 34m
Multiple Airlines
Thu 5/219:24 pm
EYW
- MYR
1 stop11h 41m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:58 pm
MYR
- EYW
1 stop19h 04m
Allegiant Air
Sun 5/242:14 pm
EYW
- MYR
1 stop22h 18m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:58 pm
MYR
- EYW
1 stop19h 04m
Multiple Airlines
Sun 5/3112:05 pm
EYW
- MYR
1 stop21h 00m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:47 pm
MYR
- EYW
2 stops17h 11m
Multiple Airlines
Wed 6/311:46 am
EYW
- MYR
1 stop27h 28m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MYR
- EYW
1 stop4h 53m
Delta
Tue 6/96:24 pm
EYW
- MYR
1 stop5h 35m
Delta
Deal found 5/3![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:50 am
MYR
- EYW
1 stop5h 26m
American Airlines
Tue 6/911:28 am
EYW
- MYR
2 stops10h 18m
American Airlines
Deal found 5/3![American Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:27 pm
MYR
- EYW
2 stops19h 45m
Multiple Airlines
Thu 6/1811:04 am
EYW
- MYR
1 stop27h 26m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
MYR
- EYW
1 stop15h 29m
Multiple Airlines
Fri 6/1912:07 pm
EYW
- MYR
2 stops32h 04m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
MYR
- EYW
1 stop15h 29m
Breeze Airways
Fri 6/191:11 pm
EYW
- MYR
1 stop22h 28m
Breeze Airways
Deal found 4/30![Breeze Airways logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
MYR
- EYW
1 stop15h 29m
Breeze Airways
Thu 6/1811:04 am
EYW
- MYR
1 stop4h 10m
Breeze Airways
Deal found 5/2![Breeze Airways logo]()
$363
One-way flights from Myrtle Beach to Key WestSearch for one-way flight options from Myrtle Beach to Key West. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
Search for one-way flight options from Myrtle Beach to Key West. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:01 pm
MYR
- EYW
2 stops17h 26m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:12 pm
MYR
- EYW
1 stop18h 19m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:44 pm
MYR
- EYW
2 stops14h 41m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:14 pm
MYR
- EYW
3 stops42h 53m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$231
Find flight deals from Myrtle Beach to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $283 (Kiwi.com) |
One-way from | $125 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sun 5/17
3:53 pm-11:27 am
1 stop19h 34m
Key West
Thu 5/21
9:24 pm-9:05 am
1 stop11h 41m
$283
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sat 5/16
11:43 am-5:23 pm
1 stop5h 40m
Key West
Mon 5/18
6:19 pm-11:58 pm
1 stop5h 39m
$404
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 6/4
3:53 pm-11:27 am
1 stop19h 34m
Key West
Sun 6/7
9:16 pm-7:57 pm
2 stops22h 41m
$441
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 5/29
11:43 am-5:23 pm
1 stop5h 40m
Key West
Tue 6/2
6:19 pm-11:58 pm
1 stop5h 39m
$479
Quickest round-trip
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 5/8
6:00 am-10:53 am
1 stop4h 53m
Key West
Sat 5/16
7:30 am-12:40 pm
1 stop5h 10m
$504
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 5/29
1:30 pm-7:49 pm
1 stop6h 19m
Key West
Wed 6/3
6:19 pm-11:58 pm
1 stop5h 39m
$547
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Tue 5/19
6:00 am-12:27 pm
1 stop6h 27m
Key West
Sat 5/23
6:19 pm-11:59 pm
1 stop5h 40m
$609
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 5/28
3:53 pm-10:27 am
3 stops18h 34m
Key West
Sun 5/31
11:04 am-11:39 am
1 stop24h 35m
$692
Cheapest one-way
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 5/14
5:01 pm-10:27 am
2 stops17h 26m
$134
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 5/14
6:12 pm-12:31 pm
1 stop18h 19m
$168
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Key West in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Myrtle Beach with our price prediction graph.
MYR-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Key West
What is the cheapest month to book a flight from Myrtle Beach to Key West?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Key West (average of $335). Flying from Myrtle Beach to Key West in March is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to Key West?
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated May 5, 2026.
See what other customers who have flown with Delta and American Airlines from Myrtle Beach to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Entertainment
7.8
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Comfort
7.9
Entertainment
7.8
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Comfort
7.9
Entertainment
7.8
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 5, 2026.
Myrtle Beach and Key West flights
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Other flights from Myrtle Beach
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Top 2 airlines flying from Myrtle Beach to Key West
Discover the top 2 airlines that operate flights from Myrtle Beach to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$258 | Average$435 | FlexibilityNo cancel fee | On-time71% |