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Key West

$119+ Cheap flights from Myrtle Beach to Key West (MYR - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Key West

Cheapest flights from Myrtle Beach to Key West
Explore the most affordable flight options available from Myrtle Beach to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:28 pm
MYR
-
EYW
1 stop17h 02m
Spirit Airlines
Wed 4/112:25 pm
EYW
-
MYR
1 stop5h 08m
Spirit Airlines
Deal found 2/15$231
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:28 pm
MYR
-
EYW
1 stop17h 02m
Spirit Airlines
Thu 3/1912:25 pm
EYW
-
MYR
1 stop5h 08m
Spirit Airlines
Deal found 2/14$232
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:28 pm
MYR
-
EYW
1 stop19h 09m
Spirit Airlines
Mon 3/162:35 pm
EYW
-
MYR
1 stop26h 58m
Spirit Airlines
Deal found 2/15$235
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:28 pm
MYR
-
EYW
1 stop19h 09m
Spirit Airlines
Mon 3/302:35 pm
EYW
-
MYR
1 stop26h 58m
Spirit Airlines
Deal found 2/14$240
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:05 pm
MYR
-
EYW
1 stop23h 06m
Multiple Airlines
Tue 3/3112:25 pm
EYW
-
MYR
1 stop5h 08m
Multiple Airlines
Deal found 2/17$244
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:28 pm
MYR
-
EYW
1 stop17h 02m
Multiple Airlines
Sun 4/59:46 am
EYW
-
MYR
1 stop4h 36m
Multiple Airlines
Deal found 2/16$248
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:28 pm
MYR
-
EYW
1 stop17h 02m
Spirit Airlines
Tue 3/2412:25 pm
EYW
-
MYR
1 stop5h 08m
Spirit Airlines
Deal found 2/17$254
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:28 pm
MYR
-
EYW
1 stop17h 02m
Spirit Airlines
Wed 3/2512:25 pm
EYW
-
MYR
1 stop5h 08m
Spirit Airlines
Deal found 2/18$255
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:26 am
MYR
-
EYW
2 stops8h 46m
American Airlines
Tue 3/316:34 pm
EYW
-
MYR
1 stop4h 22m
American Airlines
Deal found 2/17$256
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:28 pm
MYR
-
EYW
2 stops14h 38m
Multiple Airlines
Wed 4/111:51 am
EYW
-
MYR
1 stop23h 14m
Multiple Airlines
Deal found 2/16$257
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:14 pm
MYR
-
EYW
1 stop18h 20m
Multiple Airlines
Fri 5/1512:06 pm
EYW
-
MYR
1 stop21h 35m
Multiple Airlines
Deal found 2/15$261

Find flight deals from Myrtle Beach to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$231
(Kiwi.com)

One-way from

$119
(Kiwi.com)

Popular in

February

Cheapest in

January

Average price

$639
Provider with most accurate pricing for Myrtle Beach Intl-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Key West flights.
Search Deals
From Myrtle Beach Intl to Key West
Search Deals
One-way flight from Myrtle Beach Intl to Key West
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Myrtle Beach

Fly to

Key West

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 3/25

6:28 pm-11:30 am

1 stop17h 02m

Key West

Wed 4/1

12:25 pm-5:33 pm

1 stop5h 08m

$231

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/16

6:28 pm-11:30 am

1 stop17h 02m

Key West

Thu 3/19

12:25 pm-5:33 pm

1 stop5h 08m

$232

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 3/12

6:28 pm-1:37 pm

1 stop19h 09m

Key West

Mon 3/16

2:35 pm-5:33 pm

1 stop26h 58m

$235

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 3/26

6:28 pm-1:37 pm

1 stop19h 09m

Key West

Mon 3/30

2:35 pm-5:33 pm

1 stop26h 58m

$240

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/24

12:05 pm-11:11 am

1 stop23h 06m

Key West

Tue 3/31

12:25 pm-5:33 pm

1 stop5h 08m

$244

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

12:50 pm-11:25 am

1 stop22h 35m

Key West

Thu 5/14

12:06 pm-9:41 am

1 stop21h 35m

$244

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 4/1

6:28 pm-11:30 am

1 stop17h 02m

Key West

Sun 4/5

9:46 am-2:22 pm

1 stop4h 36m

$248

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:28 pm-11:30 am

1 stop17h 02m

Key West

Tue 3/24

12:25 pm-5:33 pm

1 stop5h 08m

$254

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 3/25

6:28 pm-9:06 am

2 stops14h 38m

Key West

Wed 4/1

11:51 am-11:05 am

1 stop23h 14m

$257

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/16

6:28 pm-11:30 am

1 stop17h 02m

Key West

Mon 3/23

2:35 pm-5:33 pm

1 stop26h 58m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Showing 1-10 of 17 results
1
2

Compare providers for flights from Myrtle Beach to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Key West in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key West

What is the cheapest month to book a flight from Myrtle Beach to Key West?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key West (average of $96). Flying from Myrtle Beach to Key West in February is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated February 18, 2026.
See what other customers who have flown with Delta and American Airlines from Myrtle Beach to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,207 reviews
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,304 reviews
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Key West?

    There are many flights that can get you from Myrtle Beach to Key West in 17h 02m. Fly via Spirit Airlines to get the fastest option. There are 653 mi between Myrtle Beach and Key West.

  • What are the cheapest airlines flying from Myrtle Beach to Key West round-trip?

    According to our current data, Delta ($223), and American Airlines ($263) offers the cheapest pricing from Myrtle Beach to Key West. Users have found that Delta is 49% cheaper than the other options available to this destination.

  • Can I find deals for flights from Myrtle Beach to Key West that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key West.

  • Can I find deals for business class flights from Myrtle Beach to Key West?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key West?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key West (average of $96). Flying from Myrtle Beach to Key West in February is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Myrtle Beach to Key West

Discover the top 2 airlines that operate flights from Myrtle Beach to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$223Average$438FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$429FlexibilityNo cancel feeOn-time71%

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