
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (Kiwi.com) |
One-way from | $218 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $514 |
Fly from
Fly to
Route
Depart
Return
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Mon 11/16
1:53 pm-12:36 pm
2 stops22h 43m
Key West
Fri 11/20
12:59 pm-11:44 am
1 stop22h 45m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Tue 11/10
4:03 pm-10:19 am
3 stops42h 16m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Sat 11/14
5:58 pm-11:21 am
1 stop17h 23m
Key West
Wed 11/18
10:04 am-3:08 pm
2 stops29h 04m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Thu 12/10
6:25 pm-3:08 pm
1 stop20h 43m
Key West
Mon 12/14
10:59 am-10:05 am
1 stop23h 06m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Fri 11/13
6:12 pm-9:24 am
1 stop15h 12m
Key West
Tue 11/17
1:16 pm-9:13 am
2 stops19h 57m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Thu 2/18
6:25 pm-12:19 pm
1 stop17h 54m
Key West
Mon 2/22
10:59 am-10:05 am
1 stop23h 06m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Thu 12/10
6:25 pm-3:08 pm
1 stop20h 43m
Key West
Sun 12/13
7:22 pm-8:45 am
1 stop13h 23m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Tue 11/17
4:03 pm-9:24 am
2 stops17h 21m
Key West
Sat 11/21
10:04 am-12:14 pm
1 stop26h 10m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Tue 11/10
1:52 pm-6:01 pm
1 stop4h 09m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Mon 11/23
6:12 pm-9:24 am
1 stop15h 12m
Key West
Sat 11/28
10:11 pm-8:50 am
1 stop10h 39m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
Everything you need to know about your flight from Myrtle Beach to Key West
Boarding
Entertainment
Crew
Food
Comfort
Overall
Reviews
Joel,May 2026
ATL - JAX
Boarding
Entertainment
Crew
Food
Comfort
Overall
Reviews
Joel,May 2026
ATL - JAX
Boarding
Entertainment
Crew
Food
Comfort
Overall
Reviews
Joel,May 2026
ATL - JAX
Find useful and relevant information for your journey from Myrtle Beach to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$302 | Average$502 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$305 | Average$487 | FlexibilityNo cancel fee | On-timeN/A |