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Key West

$217+ Cheap flights from Mississippi to Key West (EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — EYW
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Mississippi to Key West

Cheapest flights from Mississippi to Key West
Explore the most affordable flight options available from Mississippi to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:17 pmMEM - EYW
1 stop10h 58mMultiple Airlines
Thu 12/2510:59 amEYW - MEM
1 stop8h 32mMultiple Airlines
Deal found 12/16$331
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:11 pmMEM - EYW
1 stop13h 06mMultiple Airlines
Mon 12/2910:01 pmEYW - MEM
1 stop23h 01mMultiple Airlines
Deal found 12/17$351
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:11 pmMEM - EYW
1 stop10h 56mMultiple Airlines
Wed 12/312:30 pmEYW - MEM
2 stops25h 38mMultiple Airlines
Deal found 12/17$381
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:11 pmMEM - EYW
1 stop13h 06mMultiple Airlines
Wed 12/312:30 pmEYW - MEM
2 stops25h 38mMultiple Airlines
Deal found 12/17$397
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:30 amMOB - EYW
1 stop7h 13mDelta
Thu 1/87:10 amEYW - MOB
1 stop5h 35mDelta
Deal found 12/16$404
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:11 pmMEM - EYW
1 stop13h 06mBreeze Airways
Tue 12/3010:59 amEYW - MEM
1 stop8h 32mBreeze Airways
Deal found 12/17$408
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:47 pmMEM - EYW
1 stop16h 52mMultiple Airlines
Thu 1/110:59 amEYW - MEM
1 stop8h 32mMultiple Airlines
Deal found 12/17$416
This Kiwi.com deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:47 pmMEM - EYW
1 stop9h 20mMultiple Airlines
Sat 1/310:35 pmEYW - MEM
2 stops17h 33mMultiple Airlines
Deal found 12/18$424
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:17 pmMEM - EYW
1 stop10h 58mMultiple Airlines
Mon 12/222:30 pmEYW - MEM
2 stops53h 52mMultiple Airlines
Deal found 12/16$432
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:48 pmMEM - EYW
2 stops15h 31mBreeze Airways
Thu 1/110:59 amEYW - MEM
1 stop8h 32mBreeze Airways
Deal found 12/17$435
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:05 amMEM - EYW
1 stop5h 02mDelta
Wed 12/2411:47 amEYW - MEM
1 stop7h 27mDelta
Deal found 12/15$456
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 amMOB - EYW
1 stop7h 29mUnited Airlines
Tue 12/231:25 pmEYW - MOB
1 stop8h 05mUnited Airlines
Deal found 12/17$474

Find flight deals from Mississippi to Key West

Keep the following information in mind while searching for Mississippi to Key West flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$217
(Kiwi.com)
Provider with most accurate pricing for Jackson-Evers Intl-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Key West flights.
Search Deals
From Mississippi to Key West
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mississippi to Key West that are best for you.

Fly from

Mississippi

Fly to

Key West

Route

Depart

Return

Price

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Sun 2/8

4:52 pm-9:09 am

1 stop15h 17m

Key West

Thu 2/12

11:01 am-4:12 pm

1 stop6h 11m

$217

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Thu 1/1

8:17 pm-12:30 pm

1 stop15h 13m

Key West

Thu 1/8

3:46 pm-2:50 pm

1 stop24h 04m

$236

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Sun 3/22

8:55 pm-9:09 am

1 stop11h 14m

Key West

Thu 3/26

11:01 am-4:12 pm

1 stop6h 11m

$271

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Wed 2/4

11:44 am-9:06 am

1 stop20h 22m

Key West

Sun 2/8

12:51 pm-7:28 pm

1 stop7h 37m

$276

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Sun 2/8

4:52 pm-9:09 am

1 stop15h 17m

Key West

Thu 2/12

9:46 am-6:09 pm

2 stops9h 23m

$281

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Tue 4/14

7:43 am-1:03 pm

1 stop4h 20m

Key West

Sat 4/18

7:34 pm-11:59 pm

1 stop5h 25m

$283

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Thu 3/5

11:14 am-12:26 pm

1 stop24h 12m

Key West

Mon 3/9

9:49 am-4:45 pm

2 stops7h 56m

$337

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Wed 2/25

8:23 am-3:56 pm

1 stop6h 33m

Key West

Sun 3/1

7:54 pm-11:58 pm

1 stop5h 04m

$338

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Sat 1/24

3:48 pm-9:47 pm

1 stop4h 59m

Key West

Thu 1/29

1:22 pm-5:12 pm

1 stop4h 50m

$338

JacksonKey West

JAN - EYW

JANEYW

Jackson-Evers Intl

Sat 4/18

6:25 am-12:51 pm

1 stop5h 26m

Key West

Sat 4/25

7:34 pm-11:59 pm

1 stop5h 25m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 32 results
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Best time to book a flight from Mississippi to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Key West

What is the cheapest month to book a flight from Mississippi to Key West?

Currently, June is the cheapest month in which you can book a flight from Mississippi to Key West (average of $212). Flying from Mississippi to Key West in January is currently the most expensive (average of $696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from Mississippi?

    Key West (EYW), located 2.6 mi from the city center, is the airport you fly into when you book flights from Mississippi to Key West.

  • How long is the flight from Mississippi to Key West?

    There are many flights that can get you from Mississippi to Key West in 5h 26m. Fly via Breeze Airways, American Airlines, or Delta to get the fastest option. The distance from Mississippi to Key West is about 735 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Mississippi to Key West?

    The most popular flight routes from Mississippi to Key West are Memphis - Key West, Mobile - Key West and Jackson-Evers Intl - Key West.

  • Can I find deals for flights from Mississippi to Key West that include hotel bookings?

    Yes. In addition to deals on Mississippi to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Key West.

  • Can I find deals for business class flights from Mississippi to Key West?

    Yes. Cheapflights offers flight deals from Mississippi to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Key West?

    Currently, June is the cheapest month in which you can book a flight from Mississippi to Key West (average of $212). Flying from Mississippi to Key West in January is currently the most expensive (average of $696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Key West

Discover the top 2 airlines that operate flights from Mississippi to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$556FlexibilityNo cancel feeOn-timeN/A

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