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Key West

$226+ Cheap flights from Mississippi to Key West (EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — EYW
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheap flight deals from Mississippi to Key West

Keep the following information in mind while searching for Mississippi to Key West flight deals. Data was last updated September 19, 2025.

Round-trip from

$254
(Kiwi.com)

One-way from

$239
(Delta)
From Mississippi to Key West
Search Deals
One-way flight from Mississippi to Key West
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Find flight deals from Mississippi to Key West

Cheapest flights from Mississippi to Key West
Explore the most affordable flight options available from Mississippi to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/231:41 pmMEM - EYW
1 stop23h 42mMultiple Airlines
Thu 11/2710:59 amEYW - MEM
1 stop8h 32mMultiple Airlines
Deal found 9/16$226
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:48 pmMEM - EYW
2 stops16h 17mMultiple Airlines
Fri 10/318:55 amEYW - MEM
1 stop15h 13mMultiple Airlines
Deal found 9/17$254
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:30 pmMEM - EYW
1 stop9h 52mAllegiant Air
Sun 10/53:30 pmEYW - MEM
1 stop24h 19mAllegiant Air
Deal found 9/16$265
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:15 amBTR - EYW
1 stop4h 12mDelta
Sat 11/17:40 amEYW - BTR
1 stop5h 46mDelta
Deal found 9/15$266
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:11 pmMEM - EYW
1 stop13h 06mMultiple Airlines
Sun 11/168:55 amEYW - MEM
1 stop7h 19mMultiple Airlines
Deal found 9/16$269
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:11 pmMEM - EYW
1 stop13h 06mBreeze Airways
Thu 11/2710:59 amEYW - MEM
1 stop8h 32mBreeze Airways
Deal found 9/17$270
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:29 amMEM - EYW
1 stop5h 54mDelta
Sat 11/226:18 pmEYW - MEM
1 stop6h 02mDelta
Deal found 9/17$283
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/271:32 pmBTR - EYW
1 stop5h 35mDelta
Wed 10/17:00 amEYW - BTR
1 stop6h 52mDelta
Deal found 9/15$284
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:10 pmJAN - EYW
1 stop3h 57mDelta
Wed 10/17:00 amEYW - JAN
1 stop6h 26mDelta
Deal found 9/16$284
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:48 pmMEM - EYW
2 stops15h 19mMultiple Airlines
Sun 10/58:55 amEYW - MEM
1 stop7h 17mMultiple Airlines
Deal found 9/16$287
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:37 amMEM - EYW
2 stops7h 24mAmerican Airlines
Sat 11/2211:52 amEYW - MEM
1 stop7h 09mAmerican Airlines
Deal found 9/17$288
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:00 amMEM - EYW
1 stop24h 15mMultiple Airlines
Sun 10/53:30 pmEYW - MEM
1 stop24h 19mMultiple Airlines
Deal found 9/16$295

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Mississippi to Key West that are best for you.

Fly from

Mississippi

Fly to

Key West

Route

Depart

Return

Price

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Sun 11/23

1:41 pm-2:23 pm

1 stop23h 42m

Key West

Thu 11/27

10:59 am-6:31 pm

1 stop8h 32m

$226

Baton RougeKey West

BTR - EYW

BTREYW

Baton Rouge Ryan

Sat 10/25

6:15 am-11:27 am

1 stop4h 12m

Key West

Sat 11/1

7:40 am-12:26 pm

1 stop5h 46m

$266

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Sun 11/23

7:11 pm-9:17 am

1 stop13h 06m

Key West

Thu 11/27

10:59 am-6:31 pm

1 stop8h 32m

$270

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Wed 11/19

10:29 am-5:23 pm

1 stop5h 54m

Key West

Sat 11/22

6:18 pm-11:20 pm

1 stop6h 02m

$283

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Fri 10/3

5:48 pm-10:07 am

2 stops15h 19m

Key West

Sun 10/5

8:55 am-3:12 pm

1 stop7h 17m

$287

Baton RougeKey West

BTR - EYW

BTREYW

Baton Rouge Ryan

Wed 10/1

1:32 pm-8:07 pm

1 stop5h 35m

Key West

Mon 10/20

1:57 pm-6:19 pm

1 stop5h 22m

$299

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Wed 11/12

4:19 pm-8:15 am

1 stop14h 56m

Key West

Sun 11/16

8:55 am-3:14 pm

1 stop7h 19m

$302

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Fri 10/17

5:48 pm-10:07 am

2 stops15h 19m

Key West

Mon 10/20

8:55 am-11:08 pm

1 stop15h 13m

$305

GulfportKey West

GPT - EYW

GPTEYW

Gulfport Biloxi Regional

Thu 10/2

7:55 pm-8:15 am

1 stop11h 20m

Key West

Thu 10/16

8:55 am-7:15 pm

1 stop11h 20m

$311

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Wed 10/1

7:00 am-8:15 am

1 stop24h 15m

Key West

Sat 10/4

10:47 am-7:27 am

2 stops21h 40m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 36 results
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Best time to book a flight from Mississippi to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Key West

What is the cheapest month to book a flight from Mississippi to Key West?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Key West (average of $328). Flying from Mississippi to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from Mississippi?

    Key West (EYW), located 2.6 mi from the city center, is the airport you fly into when you book flights from Mississippi to Key West.

  • How long is the flight from Mississippi to Key West?

    There are many flights that can get you from Mississippi to Key West in 4h 12m. Fly via Delta, Breeze Airways, or American Airlines to get the fastest option. The distance from Mississippi to Key West is about 707 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mississippi to Key West one-way?

    One-way options have recently been found by users for as low as $239 on Delta. Other airlines that offer cheap prices include American Airlines from $244 and United Airlines from $426 one-way.

  • What are the most popular routes from Mississippi to Key West?

    The most popular flight routes from Mississippi to Key West are Memphis - Key West, Gulfport Biloxi Regional - Key West and Mobile - Key West.

  • Can I find deals for flights from Mississippi to Key West that include hotel bookings?

    Yes. In addition to deals on Mississippi to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Key West.

  • Can I find deals for business class flights from Mississippi to Key West?

    Yes. Cheapflights offers flight deals from Mississippi to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Key West?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Key West (average of $328). Flying from Mississippi to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Key West

Discover the top 2 airlines that operate flights from Mississippi to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$560FlexibilityNo cancel feeOn-timeN/A

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