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Key Largo

$163+ Cheap flights from Medford (MFR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — MIA
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Medford to Key Largo

Keep the following information in mind while searching for Medford to Key Largo flight deals. Data was last updated September 14, 2025.

Round-trip from

$409
(Alaska Airlines)

One-way from

$163
(Alaska Airlines)

Popular in

December

Cheapest in

January

Average price

$404
From Medford to Key Largo
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One-way flight from Medford to Key Largo
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Highest demand for flights based on searches. 10% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Medford to Key Largo

Cheapest flights from Medford to Key Largo
Explore the most affordable flight options available from Medford to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:15 amMFR - MIA
1 stop8h 08mDelta
Tue 10/76:45 pmMIA - MFR
1 stop8h 04mDelta
Deal found 9/14$366
This Alaska Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:35 pmMFR - MIA
1 stop24h 11mAlaska Airlines
Fri 11/214:57 pmMIA - MFR
1 stop25h 15mAlaska Airlines
Deal found 9/14$409
This Alaska Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:43 amMFR - MIA
1 stop9h 02mAlaska Airlines
Mon 10/66:43 pmMIA - MFR
1 stop19h 33mAlaska Airlines
Deal found 9/14$411
This Alaska Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:47 pmMFR - MIA
1 stop20h 58mAlaska Airlines
Wed 10/16:49 pmMIA - MFR
1 stop8h 44mAlaska Airlines
Deal found 9/11$425
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:20 amMFR - MIA
2 stops10h 10mAmerican Airlines
Fri 11/215:32 pmMIA - MFR
1 stop8h 32mAmerican Airlines
Deal found 9/14$430
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:15 amMFR - MIA
1 stop8h 08mDelta
Wed 10/112:25 pmMIA - MFR
2 stops14h 28mDelta
Deal found 9/11$431
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:00 amMFR - MIA
2 stops12h 01mUnited Airlines
Wed 10/18:05 amMIA - MFR
2 stops12h 47mUnited Airlines
Deal found 9/11$436
This Alaska Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:02 pmMFR - MIA
1 stop26h 44mAlaska Airlines
Sun 11/96:46 pmMIA - MFR
1 stop19h 44mAlaska Airlines
Deal found 9/13$441

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Medford to Key Largo that are best for you.

Fly from

Medford

Fly to

Key Largo

Route

Depart

Return

Price

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sun 3/1

5:05 am-3:42 pm

1 stop7h 37m

Miami

Tue 3/3

5:55 pm-12:09 am

1 stop9h 14m

$344

MedfordMiami

MFR - MIA

MFRMIA

Medford

Fri 3/6

11:45 am-4:55 pm

1 stop26h 10m

Miami

Tue 3/10

5:55 pm-12:09 am

1 stop9h 14m

$371

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 11/15

1:26 pm-5:46 pm

1 stop25h 20m

Miami

Fri 11/21

4:57 pm-3:12 pm

1 stop25h 15m

$409

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 9/27

5:47 pm-5:45 pm

1 stop20h 58m

Miami

Wed 10/1

6:49 pm-12:33 am

1 stop8h 44m

$425

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 11/15

5:20 am-6:30 pm

2 stops10h 10m

Miami

Fri 11/21

5:32 pm-11:04 pm

1 stop8h 32m

$430

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 9/27

6:15 am-5:23 pm

1 stop8h 08m

Miami

Wed 10/1

12:25 pm-11:53 pm

2 stops14h 28m

$431

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 9/27

6:00 am-9:01 pm

2 stops12h 01m

Miami

Wed 10/1

8:05 am-5:52 pm

2 stops12h 47m

$436

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 1/3

3:30 pm-6:05 am

1 stop11h 35m

Miami

Fri 1/9

4:45 pm-11:10 am

2 stops21h 25m

$436

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 10/25

12:02 pm-5:46 pm

1 stop26h 44m

Miami

Sun 11/9

6:46 pm-11:30 am

1 stop19h 44m

$441

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 10/25

2:22 pm-5:00 am

2 stops11h 38m

$163

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 18 results
1
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Best time to book a flight from Medford to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Key Largo

What is the cheapest month to book a flight from Medford to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Medford to Key Largo (average of $232). Flying from Medford to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to KE9?

Find hourly flight availability from Medford to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

When flying from Medford to Key Largo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated September 14, 2025.
See what other customers who have flown with Alaska Airlines, United Airlines, and American Airlines from Medford to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,931 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Key Largo?

    Medford (MFR) is the airport you will fly out of if you book a flight from Medford to Key Largo. You should not have trouble finding flights to Key Largo from Medford; the airport handles an average of 0 outbound flights to Key Largo per day. You should also have plenty of airline options to choose from since 5 airlines have flights from the Medford airport to Key Largo. It is only a 3.0 mi journey to Medford (MFR) from Medford’s city center.

  • How long is the flight from Medford to Key Largo?

    Departing from Medford to Key Largo will take you 7h 37m. The distance between Medford and Key Largo is about 2656 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Medford to Key Largo one-way?

    The cheapest airlines for a one-way flight from Medford to Key Largo are American Airlines ($163), Delta ($163), and Alaska Airlines ($163).

  • Can I find deals for flights from Medford to Key Largo that include hotel bookings?

    Yes. In addition to deals on Medford to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Key Largo.

  • Can I find deals for business class flights from Medford to Key Largo?

    Yes. Cheapflights offers flight deals from Medford to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Medford to Key Largo (average of $232). Flying from Medford to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Medford to Key Largo

Discover the top 5 airlines that operate flights from Medford to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$528FlexibilityNo cancel feeOn-timeN/A
Hawaiian AirlinesCheapest$269Average$469FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$307Average$488FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$345Average$654FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$374Average$541FlexibilityNo cancel feeOn-time71%

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