Key Largo

$170+ Cheap flights from Medford (MFR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — MIA
Mar 7 — Mar 141
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Cheap flight deals from Medford to Key Largo

Cheapest flights from Medford to Key Largo
Explore the most affordable flight options available from Medford to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:13 am
MFR
-
MIA
1 stop10h 10m
American Airlines
Wed 3/117:07 am
MIA
-
MFR
1 stop9h 25m
American Airlines
Deal found 2/2$329
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:35 pm
MFR
-
MIA
1 stop7h 58m
United Airlines
Wed 3/1110:22 am
MIA
-
MFR
2 stops15h 36m
United Airlines
Deal found 2/2$334
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:55 am
MFR
-
MIA
2 stops12h 56m
Delta
Wed 3/116:55 am
MIA
-
MFR
2 stops12h 40m
Delta
Deal found 2/2$339
This Alaska Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:40 am
MFR
-
MIA
1 stop29h 04m
Alaska Airlines
Tue 3/105:59 pm
MIA
-
MFR
1 stop22h 03m
Alaska Airlines
Deal found 2/4$350
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:02 am
MFR
-
MIA
1 stop7h 55m
United Airlines
Thu 3/57:45 am
MIA
-
MFR
1 stop8h 34m
United Airlines
Deal found 2/3$359
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:25 pm
MFR
-
MIA
1 stop10h 04m
United Airlines
Sat 8/157:00 am
MIA
-
MFR
2 stops13h 50m
United Airlines
Deal found 2/3$360
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/283:20 pm
MFR
-
MIA
2 stops11h 08m
Delta
Tue 3/102:39 pm
MIA
-
MFR
2 stops11h 10m
Delta
Deal found 2/3$364
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:05 am
MFR
-
MIA
1 stop8h 22m
Delta
Sat 11/148:05 am
MIA
-
MFR
2 stops11h 38m
Delta
Deal found 2/3$384
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:21 pm
MFR
-
MIA
2 stops9h 46m
Delta
Mon 9/146:50 am
MIA
-
MFR
1 stop8h 43m
Delta
Deal found 2/2$389
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:30 am
MFR
-
MIA
2 stops14h 58m
Delta
Tue 3/102:39 pm
MIA
-
MFR
2 stops12h 08m
Delta
Deal found 2/4$394
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/212:00 pm
MFR
-
MIA
2 stops12h 51m
United Airlines
Wed 2/2510:58 am
MIA
-
MFR
2 stops13h 20m
United Airlines
Deal found 2/5$399

Find flight deals from Medford to Key Largo

Keep the following information in mind while searching for Medford to Key Largo flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(American Airlines)

One-way from

$170
(Alaska Airlines)

Popular in

December

Cheapest in

September

Average price

$460
Provider with most accurate pricing for Medford-Miami flight deals.
Provider most trusted by Cheapflights users for Medford-Miami flights.
From Medford to Key Largo
One-way flight from Medford to Key Largo
Highest demand for flights based on searches. 8% potential increase in price ($52 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Medford to Key Largo that are best for you.

Fly from

Medford

Fly to

Key Largo

Route

Depart

Return

Price

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 3/3

12:35 pm-11:33 pm

1 stop7h 58m

Miami

Wed 3/11

10:22 am-10:58 pm

2 stops15h 36m

$334

MedfordMiami

MFR - MIA

MFRMIA

Medford

Wed 3/4

6:55 am-12:53 am

2 stops14h 58m

Miami

Thu 3/5

6:43 am-12:11 pm

1 stop8h 28m

$334

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 3/3

5:55 am-9:51 pm

2 stops12h 56m

Miami

Wed 3/11

6:55 am-4:35 pm

2 stops12h 40m

$339

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 2/28

7:40 am-3:44 pm

1 stop29h 04m

Miami

Tue 3/10

5:59 pm-1:02 pm

1 stop22h 03m

$350

MedfordMiami

MFR - MIA

MFRMIA

Medford

Wed 3/4

5:02 am-3:57 pm

1 stop7h 55m

Miami

Thu 3/5

7:45 am-1:19 pm

1 stop8h 34m

$359

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 2/28

3:20 pm-5:28 am

2 stops11h 08m

Miami

Tue 3/10

2:39 pm-10:49 pm

2 stops11h 10m

$364

MedfordMiami

MFR - MIA

MFRMIA

Medford

Fri 3/6

11:30 am-5:28 am

2 stops14h 58m

Miami

Tue 3/10

2:39 pm-10:49 pm

2 stops11h 10m

$394

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 2/21

2:00 pm-5:51 am

2 stops12h 51m

Miami

Wed 2/25

10:58 am-9:18 pm

2 stops13h 20m

$399

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sun 3/15

9:20 pm-3:37 pm

2 stops39h 17m

$180

MedfordMiami

MFR - MIA

MFRMIA

Medford

Thu 4/16

6:31 pm-11:09 am

2 stops13h 38m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 14 results
1
2

Best time to book a flight from Medford to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Key Largo

What is the cheapest month to book a flight from Medford to Key Largo?

Currently, October is the cheapest month in which you can book a flight from Medford to Key Largo (average of $166). Flying from Medford to Key Largo in December is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 5, 2026.
See what other customers who have flown with Alaska Airlines, Hawaiian Airlines, and United Airlines from Medford to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.0

Comfort

7.8

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Entertainment

7.0

Comfort

7.8

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Entertainment

7.0

Comfort

7.8

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Entertainment

7.0

Comfort

7.8

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Entertainment

7.0

Comfort

7.8

Crew

8.5

Food

7.1

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Related info for your journey

Find useful and relevant information for your journey from Medford to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Medford to Key Largo?

    Medford (MFR) is the airport you will fly out of if you book a flight from Medford to Key Largo. You should not have trouble finding flights to Key Largo from Medford; the airport handles an average of 0 outbound flights to Key Largo per day. You should also have plenty of airline options to choose from since 5 airlines have flights from the Medford airport to Key Largo. It is only a 3.0 mi journey to Medford (MFR) from Medford’s city center.

  • How long is the flight from Medford to Key Largo?

    Departing from Medford to Key Largo will take you 7h 58m. The distance between Medford and Key Largo is about 2656 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Medford to Key Largo that include hotel bookings?

    Yes. In addition to deals on Medford to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Key Largo.

  • Can I find deals for business class flights from Medford to Key Largo?

    Yes. Cheapflights offers flight deals from Medford to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Key Largo?

    Currently, October is the cheapest month in which you can book a flight from Medford to Key Largo (average of $166). Flying from Medford to Key Largo in December is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Medford to Key Largo

Discover the top 5 airlines that operate flights from Medford to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$166Average$393FlexibilityNo cancel feeOn-timeN/A
Hawaiian AirlinesCheapest$186Average$469FlexibilityNo cancel feeOn-time85%
United AirlinesCheapest$294Average$630FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$316Average$486FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$374Average$483FlexibilityNo cancel feeOn-time71%

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