HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key Largo

$185+ Cheap flights from Medford (MFR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — MIA
May 10 — May 171
Sun 5/10
Sun 5/17
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Key Largo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to Key Largo

Cheapest flights from Medford to Key Largo
Explore the most affordable flight options available from Medford to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:36 pm
MFR
-
MIA
1 stop10h 53m
United Airlines
Sun 5/247:37 am
MIA
-
MFR
1 stop8h 28m
United Airlines
Deal found 4/6$369
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:05 am
MFR
-
MIA
1 stop8h 22m
Delta
Sat 11/148:05 am
MIA
-
MFR
2 stops11h 38m
Delta
Deal found 4/9$374
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:21 pm
MFR
-
MIA
2 stops14h 24m
Delta
Tue 5/197:00 am
MIA
-
MFR
2 stops12h 33m
Delta
Deal found 4/10$389
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:28 pm
MFR
-
MIA
2 stops14h 18m
Delta
Tue 5/123:09 pm
MIA
-
MFR
2 stops11h 33m
Delta
Deal found 4/7$399
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:05 am
MFR
-
MIA
1 stop8h 22m
Delta
Sat 10/246:50 am
MIA
-
MFR
1 stop8h 46m
Delta
Deal found 4/5$404
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:00 am
MFR
-
MIA
1 stop7h 44m
United Airlines
Tue 5/197:30 am
MIA
-
MFR
1 stop8h 31m
United Airlines
Deal found 4/10$412
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:00 am
MFR
-
MIA
1 stop7h 44m
United Airlines
Sun 5/107:30 am
MIA
-
MFR
1 stop8h 31m
United Airlines
Deal found 4/6$422

Find flight deals from Medford to Key Largo

Keep the following information in mind while searching for Medford to Key Largo flight deals. Data was last updated April 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(United Airlines)

One-way from

$185
(Alaska Airlines)

Popular in

December

Cheapest in

June

Average price

$478
Provider with most accurate pricing for Medford-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Miami flights.
Search Deals
From Medford to Key Largo
Search Deals
One-way flight from Medford to Key Largo
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Medford to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sun 5/17

6:36 pm-8:29 am

1 stop10h 53m

Miami

Sun 5/24

7:37 am-1:05 pm

1 stop8h 28m

$369

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 5/5

5:28 pm-9:18 am

2 stops12h 50m

Miami

Tue 5/12

6:05 pm-11:55 pm

1 stop8h 50m

$394
Quickest round-trip

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 5/2

6:00 am-5:06 pm

1 stop8h 06m

Miami

Wed 5/6

3:25 pm-9:31 pm

1 stop9h 06m

$479

MedfordMiami

MFR - MIA

MFRMIA

Medford

Fri 7/3

4:34 pm-5:01 am

1 stop9h 27m

Miami

Tue 7/7

5:30 pm-11:59 pm

1 stop9h 29m

$489

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 4/21

11:14 am-12:54 am

2 stops10h 40m

Miami

Mon 4/27

6:42 am-11:47 am

1 stop8h 05m

$499

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 5/2

5:45 am-5:04 pm

1 stop8h 19m

Miami

Wed 5/6

6:04 pm-12:01 pm

2 stops20h 57m

$511

MedfordMiami

MFR - MIA

MFRMIA

Medford

Sat 4/25

6:34 pm-7:54 am

1 stop10h 20m

Miami

Wed 4/29

7:40 am-1:16 pm

1 stop8h 36m

$539
Cheapest one-way
Quickest one-way

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 9/1

6:00 am-5:14 pm

1 stop8h 14m

$185

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 9/1

6:05 am-11:15 pm

2 stops14h 10m

$249

MedfordMiami

MFR - MIA

MFRMIA

Medford

Tue 9/1

2:06 pm-11:54 am

3 stops18h 48m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/8

Sorted by cheapest first

Best time to book a flight from Medford to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Key Largo

What is the cheapest month to book a flight from Medford to Key Largo?

Currently, October is the cheapest month in which you can book a flight from Medford to Key Largo (average of $166). Flying from Medford to Key Largo in December is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated April 10, 2026.
See what other customers who have flown with Alaska Airlines,Hawaiian Airlines, andUnited Airlines from Medford to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
7.9
Good
12,207 reviews

Entertainment

7.0

Boarding

8.1

Food

7.0

Crew

8.5

Overall

7.9

Comfort

7.8

Reviews

1 / 20
8.0
Excellent

Eugene,Mar 2026

MFR - SEA

Alaska Airlines is is always good. There where few choices of what to drink, and no food. No blankets, no pillows, and you h ats ok. I just had open heart surgery And i could have used something. But the flight and the crew where exelent. So all is well
Alaska Airlines
7.9
Good
12,207 reviews
Alaska Airlines
7.9
Good
12,207 reviews

Entertainment

7.0

Boarding

8.1

Food

7.0

Crew

8.5

Overall

7.9

Comfort

7.8

Reviews

1 / 20
8.0
Excellent

Eugene,Mar 2026

MFR - SEA

Alaska Airlines is is always good. There where few choices of what to drink, and no food. No blankets, no pillows, and you h ats ok. I just had open heart surgery And i could have used something. But the flight and the crew where exelent. So all is well
Hawaiian Airlines
7.8
Good
2,839 reviews
Alaska Airlines
7.9
Good
12,207 reviews

Entertainment

7.0

Boarding

8.1

Food

7.0

Crew

8.5

Overall

7.9

Comfort

7.8

Reviews

1 / 20
8.0
Excellent

Eugene,Mar 2026

MFR - SEA

Alaska Airlines is is always good. There where few choices of what to drink, and no food. No blankets, no pillows, and you h ats ok. I just had open heart surgery And i could have used something. But the flight and the crew where exelent. So all is well
United Airlines
7.4
Good
9,562 reviews
Alaska Airlines
7.9
Good
12,207 reviews

Entertainment

7.0

Boarding

8.1

Food

7.0

Crew

8.5

Overall

7.9

Comfort

7.8

Reviews

1 / 20
8.0
Excellent

Eugene,Mar 2026

MFR - SEA

Alaska Airlines is is always good. There where few choices of what to drink, and no food. No blankets, no pillows, and you h ats ok. I just had open heart surgery And i could have used something. But the flight and the crew where exelent. So all is well
American Airlines
7.1
Good
11,564 reviews
Alaska Airlines
7.9
Good
12,207 reviews

Entertainment

7.0

Boarding

8.1

Food

7.0

Crew

8.5

Overall

7.9

Comfort

7.8

Reviews

1 / 20
8.0
Excellent

Eugene,Mar 2026

MFR - SEA

Alaska Airlines is is always good. There where few choices of what to drink, and no food. No blankets, no pillows, and you h ats ok. I just had open heart surgery And i could have used something. But the flight and the crew where exelent. So all is well

Related info for your journey

Find useful and relevant information for your journey from Medford to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Key Largo?

    Medford (MFR) is the airport you will fly out of if you book a flight from Medford to Key Largo. You should not have trouble finding flights to Key Largo from Medford; the airport handles an average of 0 outbound flights to Key Largo per day. You should also have plenty of airline options to choose from since 5 airlines have flights from the Medford airport to Key Largo. It is only a 3.0 mi journey to Medford (MFR) from Medford’s city center.

  • How long is the flight from Medford to Key Largo?

    Departing from Medford to Key Largo will take you 10h 53m. The distance between Medford and Key Largo is about 2656 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Medford to Key Largo that include hotel bookings?

    Yes. In addition to deals on Medford to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Key Largo.

  • Can I find deals for business class flights from Medford to Key Largo?

    Yes. Cheapflights offers flight deals from Medford to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Key Largo?

    Currently, October is the cheapest month in which you can book a flight from Medford to Key Largo (average of $166). Flying from Medford to Key Largo in December is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Medford to Key Largo

Discover the top 5 airlines that operate flights from Medford to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$166Average$379FlexibilityNo cancel feeOn-timeN/A
Hawaiian AirlinesCheapest$186Average$469FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$316Average$486FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$344Average$588FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$402Average$568FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.