$246+ Cheap flights from Des Moines (DSM) to Johnson City, TN, TN
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Johnson City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Johnson CityExplore the most affordable flight options available from Des Moines to Johnson City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Des Moines to Johnson City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:34 pm -
1 stop6h 46m
Mon 9/286:00 am -
1 stop5h 46m
Deal found 9/9![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:56 pm -
1 stop5h 00m
Wed 9/235:31 pm -
1 stop6h 41m
Deal found 9/6![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:56 pm -
1 stop5h 00m
Sun 10/48:29 pm -
1 stop4h 23m
Deal found 9/9![American Airlines logo]()
$497
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
2 stops24h 58m
Sun 10/46:03 pm -
1 stop17h 07m
Deal found 9/9![Multiple Airlines logo]()
$557
Best flights from Des Moines to Johnson CityDiscover carefully curated flight deals from Des Moines to Johnson City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Des Moines to Johnson City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:34 pm -
1 stop6h 46m
Mon 9/286:00 am -
1 stop5h 46m
Deal found 9/9![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:56 pm -
1 stop5h 00m
Sun 10/48:29 pm -
1 stop4h 23m
Deal found 9/9![American Airlines logo]()
$497
Last-minute flights from Des Moines to Johnson CityDiscover last-minute flight deals from Des Moines to Johnson City. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Johnson City. Data last updated September 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:34 pm -
1 stop6h 46m
Mon 9/286:00 am -
1 stop5h 46m
Deal found 9/9![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:56 pm -
1 stop5h 00m
Sun 10/48:29 pm -
1 stop4h 23m
Deal found 9/9![American Airlines logo]()
$497
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
2 stops24h 58m
Sun 10/46:03 pm -
1 stop17h 07m
Deal found 9/9![Multiple Airlines logo]()
$557
One-way flights from Des Moines to Johnson CitySearch for one-way flight options from Des Moines to Johnson City. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Des Moines to Johnson City. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:52 pm -
2 stops25h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$246
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:08 am -
1 stop6h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$310
Find flight deals from Des Moines to Johnson City
Keep the following information in mind while searching for Des Moines to Johnson City flight deals. Data was last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (Delta) |
One-way from | $246 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Johnson City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Des Moines to Johnson City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBlountville
DSM Des Moines - TRI Blountville Tri Cities TN/VA
DSMTRI
Des Moines
Thu 10/22
8:43 am-8:01 pm
3 stops34h 18m
Blountville Tri Cities TN/VA
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$267
Quickest round-trip
Des MoinesBlountville
DSM Des Moines - TRI Blountville Tri Cities TN/VA
DSMTRI
Des Moines
Thu 10/22
7:08 am-2:18 pm
1 stop6h 10m
Blountville Tri Cities TN/VA
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$310
Des MoinesBlountville
DSM Des Moines - TRI Blountville Tri Cities TN/VA
DSMTRI
Des Moines
Thu 9/24
2:34 pm-10:20 pm
1 stop6h 46m
Blountville Tri Cities TN/VA
Mon 9/28
6:00 am-10:46 am
1 stop5h 46m
$349
Des MoinesBlountville
DSM Des Moines - TRI Blountville Tri Cities TN/VA
DSMTRI
Des Moines
Sun 9/27
5:56 pm-11:56 pm
1 stop5h 00m
Blountville Tri Cities TN/VA
Sun 10/4
8:29 pm-11:52 pm
1 stop4h 23m
$497
Sorted by cheapest first
Best time to book a flight from Des Moines to Johnson City
Have a flexible travel schedule? Discover the best time to fly to Johnson City from Des Moines with our price prediction graph.
DSM-TRI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Johnson City
DSM-J0H
DSM-TRI
No data available for this route at this time. Please check back soon.
Related info for your journey
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Alternative routes for Des Moines to Johnson City
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Complete your trip
Complete your trip to Johnson City by adding a car rental and/or hotel reservation to your travel itinerary.
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Des Moines and Johnson City flights
Browse other Des Moines and Johnson City flight options. Last updated on September 11, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 11, 2026.
Popular flight searches
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Des Moines to Johnson City flights
Consider these flights traveling from Des Moines to Johnson City.
Top 3 airlines flying from Des Moines to Johnson City
Discover the top 3 airlines that operate flights from Des Moines to Johnson City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$361 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$203 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$495 | FlexibilityNo cancel fee | On-time69% |