$184+ Cheap flights from Des Moines (DSM) to Johnson City, TN, TN
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Aug 27 — Sep 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Johnson City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Johnson City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Johnson CityExplore the most affordable flight options available from Des Moines to Johnson City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Des Moines to Johnson City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:13 pm
DSM
- TRI
1 stop5h 37m
American Airlines
Fri 9/117:31 am
TRI
- DSM
1 stop7h 28m
American Airlines
Deal found 7/25![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:13 pm
DSM
- TRI
1 stop5h 37m
American Airlines
Sat 8/157:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/25![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:30 pm
DSM
- TRI
2 stops8h 53m
Delta
Fri 9/1110:13 am
TRI
- DSM
1 stop6h 02m
Delta
Deal found 7/25![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:33 pm
DSM
- TRI
1 stop4h 42m
American Airlines
Sat 8/87:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/25![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:38 pm
DSM
- TRI
1 stop6h 17m
American Airlines
Fri 12/118:54 am
TRI
- DSM
1 stop5h 25m
American Airlines
Deal found 7/26![American Airlines logo]()
$547
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am
DSM
- TRI
2 stops7h 55m
Delta
Fri 12/117:16 pm
TRI
- DSM
1 stop4h 18m
Delta
Deal found 7/26![Delta logo]()
$552
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/271:41 pm
DSM
- TRI
1 stop5h 19m
American Airlines
Tue 8/1112:30 pm
TRI
- DSM
2 stops7h 49m
American Airlines
Deal found 7/25![American Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:40 am
DSM
- TRI
2 stops10h 23m
American Airlines
Wed 8/127:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/24![American Airlines logo]()
$619
Best flights from Des Moines to Johnson CityDiscover carefully curated flight deals from Des Moines to Johnson City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Des Moines to Johnson City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:30 pm
DSM
- TRI
2 stops8h 53m
Delta
Fri 9/1110:13 am
TRI
- DSM
1 stop6h 02m
Delta
Deal found 7/25![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:40 am
DSM
- TRI
2 stops10h 23m
American Airlines
Wed 8/127:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/24![American Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am
DSM
- TRI
2 stops7h 55m
Delta
Fri 12/117:16 pm
TRI
- DSM
1 stop4h 18m
Delta
Deal found 7/26![Delta logo]()
$552
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:55 pm
DSM
- TRI
2 stops8h 04m
American Airlines
Sat 8/156:00 am
TRI
- DSM
2 stops8h 25m
American Airlines
Deal found 7/25![American Airlines logo]()
$671
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:40 am
DSM
- TRI
1 stop6h 21m
Delta
Wed 8/127:08 pm
TRI
- DSM
1 stop4h 29m
Delta
Deal found 7/24![Delta logo]()
$674
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:10 pm
DSM
- TRI
1 stop4h 49m
American Airlines
Fri 8/1412:30 pm
TRI
- DSM
1 stop7h 11m
American Airlines
Deal found 7/25![American Airlines logo]()
$735
Last-minute flights from Des Moines to Johnson CityDiscover last-minute flight deals from Des Moines to Johnson City. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Johnson City. Data last updated July 28, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:48 pm
DSM
- TRI
1 stop6h 40m
American Airlines
Tue 8/117:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/25![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:41 pm
DSM
- TRI
1 stop5h 19m
American Airlines
Sat 8/15:24 pm
TRI
- DSM
1 stop7h 34m
American Airlines
Deal found 7/26![American Airlines logo]()
$726
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:40 am
DSM
- TRI
2 stops10h 23m
American Airlines
Wed 8/127:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/24![American Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:40 am
DSM
- TRI
1 stop6h 21m
Delta
Wed 8/127:08 pm
TRI
- DSM
1 stop4h 29m
Delta
Deal found 7/24![Delta logo]()
$674
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:10 pm
DSM
- TRI
1 stop4h 49m
American Airlines
Fri 8/1412:30 pm
TRI
- DSM
1 stop7h 11m
American Airlines
Deal found 7/25![American Airlines logo]()
$735
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:13 pm
DSM
- TRI
1 stop5h 37m
American Airlines
Sat 8/157:40 am
TRI
- DSM
1 stop6h 45m
American Airlines
Deal found 7/25![American Airlines logo]()
$334
One-way flights from Des Moines to Johnson CitySearch for one-way flight options from Des Moines to Johnson City. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Des Moines to Johnson City. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
DSM
- TRI
2 stops21h 09m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$184
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:53 am
DSM
- TRI
1 stop5h 38m
American Airlines
Deal found 7/25![American Airlines logo]()
$195
Find flight deals from Des Moines to Johnson City
Keep the following information in mind while searching for Des Moines to Johnson City flight deals. Data was last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
One-way from | $184 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Johnson City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Des Moines to Johnson City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Sat 9/5
12:30 pm-10:23 pm
2 stops8h 53m
Blountville Tri Cities TN/VA
Fri 9/11
10:13 am-3:15 pm
1 stop6h 02m
$383
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Thu 12/10
6:00 am-2:55 pm
2 stops7h 55m
Blountville Tri Cities TN/VA
Fri 12/11
7:16 pm-10:34 pm
1 stop4h 18m
$552
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Sat 8/8
5:40 am-5:03 pm
2 stops10h 23m
Blountville Tri Cities TN/VA
Wed 8/12
7:40 am-1:25 pm
1 stop6h 45m
$619
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Thu 8/13
1:55 pm-10:59 pm
2 stops8h 04m
Blountville Tri Cities TN/VA
Sat 8/15
6:00 am-1:25 pm
2 stops8h 25m
$671
Quickest round-trip
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Sat 8/8
5:40 am-1:01 pm
1 stop6h 21m
Blountville Tri Cities TN/VA
Wed 8/12
7:08 pm-10:37 pm
1 stop4h 29m
$674
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Mon 8/10
5:10 pm-10:59 pm
1 stop4h 49m
Blountville Tri Cities TN/VA
Fri 8/14
12:30 pm-6:41 pm
1 stop7h 11m
$735
Cheapest one-way
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Sun 9/6
1:58 pm-12:07 pm
2 stops21h 09m
$184
Quickest one-way
Des MoinesBlountville
DSM - TRI
DSMTRI
Des Moines
Sun 9/6
7:53 am-2:31 pm
1 stop5h 38m
$195
Sorted by cheapest first
Best time to book a flight from Des Moines to Johnson City
Have a flexible travel schedule? Discover the best time to fly to Johnson City from Des Moines with our price prediction graph.
DSM-TRI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Johnson City
DSM-J0H
DSM-TRI
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Johnson City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
Top destinations
Alternative routes for Des Moines to Johnson City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Johnson City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Johnson City by cabin class
Find flights from Des Moines to Johnson City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Johnson City flights
Browse other Des Moines and Johnson City flight options. Last updated on July 28, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Johnson City flights
Consider these flights traveling from Des Moines to Johnson City.
Top 3 airlines flying from Des Moines to Johnson City
Discover the top 3 airlines that operate flights from Des Moines to Johnson City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$370 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$203 | Average$359 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$463 | FlexibilityNo cancel fee | On-time69% |