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$271+ Cheap flights from Syracuse (SYR) to Iowa

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — DSM
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Syracuse to Iowa

Cheapest flights from Syracuse to Iowa
Explore the most affordable flight options available from Syracuse to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:50 am
SYR
-
DSM
1 stop5h 19m
Delta
Tue 3/175:47 pm
DSM
-
SYR
1 stop4h 22m
Delta
Deal found 1/29$271
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/73:25 pm
SYR
-
DSM
2 stops9h 15m
American Airlines
Tue 3/172:00 pm
DSM
-
SYR
1 stop7h 43m
American Airlines
Deal found 1/27$276
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:00 pm
SYR
-
MLI
1 stop6h 26m
American Airlines
Sat 2/143:33 pm
MLI
-
SYR
1 stop6h 24m
American Airlines
Deal found 1/27$279
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:24 pm
SYR
-
DSM
1 stop5h 15m
American Airlines
Thu 2/265:00 am
DSM
-
SYR
1 stop5h 11m
American Airlines
Deal found 1/27$279
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1011:43 am
SYR
-
MLI
2 stops11h 50m
Delta
Sat 2/145:01 pm
MLI
-
SYR
1 stop6h 06m
Delta
Deal found 1/27$284
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/125:50 am
SYR
-
OMA
1 stop5h 08m
Delta
Mon 2/165:55 pm
OMA
-
SYR
1 stop4h 18m
Delta
Deal found 1/27$309
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:29 pm
SYR
-
DSM
1 stop5h 39m
American Airlines
Sun 2/155:00 am
DSM
-
SYR
1 stop5h 13m
American Airlines
Deal found 1/26$309
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:03 am
SYR
-
MLI
2 stops10h 51m
United Airlines
Sat 2/1412:21 pm
MLI
-
SYR
2 stops10h 00m
United Airlines
Deal found 1/27$320
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:12 pm
SYR
-
DSM
1 stop5h 41m
American Airlines
Sun 4/266:00 am
DSM
-
SYR
1 stop4h 06m
American Airlines
Deal found 1/26$357
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:20 pm
SYR
-
DSM
1 stop17h 08m
American Airlines
Tue 5/191:38 pm
DSM
-
SYR
1 stop8h 01m
American Airlines
Deal found 1/27$359
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:00 am
SYR
-
OMA
1 stop9h 09m
United Airlines
Sat 10/3111:21 am
OMA
-
SYR
1 stop4h 36m
United Airlines
Deal found 1/28$370
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/74:57 pm
SYR
-
MLI
1 stop5h 39m
United Airlines
Tue 2/1010:47 am
MLI
-
SYR
1 stop4h 28m
United Airlines
Deal found 1/26$379

Find flight deals from Syracuse to Iowa

Keep the following information in mind while searching for Syracuse to Iowa flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Delta)

Popular in

July

Cheapest in

April

Average price

$394
Provider with most accurate pricing for Syracuse Hancock Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Des Moines flights.
Search Deals
From Syracuse Hancock Intl to Iowa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Syracuse to Iowa that are best for you.

Fly from

Syracuse

Fly to

Iowa

Route

Depart

Return

Price

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Sat 3/7

5:50 am-10:09 am

1 stop5h 19m

Des Moines

Tue 3/17

5:47 pm-11:09 pm

1 stop4h 22m

$271

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Sat 3/7

3:25 pm-11:40 pm

2 stops9h 15m

Des Moines

Tue 3/17

2:00 pm-10:43 pm

1 stop7h 43m

$276

SyracuseMoline

SYR - MLI

SYRMLI

Syracuse Hancock Intl

Tue 2/10

5:00 pm-10:26 pm

1 stop6h 26m

Moline Quad-City

Sat 2/14

3:33 pm-10:57 pm

1 stop6h 24m

$279

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Sat 2/21

5:24 pm-9:39 pm

1 stop5h 15m

Des Moines

Thu 2/26

5:00 am-11:11 am

1 stop5h 11m

$279

SyracuseMoline

SYR - MLI

SYRMLI

Syracuse Hancock Intl

Tue 2/10

11:43 am-10:33 pm

2 stops11h 50m

Moline Quad-City

Sat 2/14

5:01 pm-12:07 am

1 stop6h 06m

$284

SyracuseOmaha

SYR - OMA

SYROMA

Syracuse Hancock Intl

Thu 2/12

5:50 am-9:58 am

1 stop5h 08m

Omaha Eppley Airfield

Mon 2/16

5:55 pm-11:13 pm

1 stop4h 18m

$309

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Wed 2/11

6:29 pm-11:08 pm

1 stop5h 39m

Des Moines

Sun 2/15

5:00 am-11:13 am

1 stop5h 13m

$309

SyracuseMoline

SYR - MLI

SYRMLI

Syracuse Hancock Intl

Tue 2/10

7:03 am-4:54 pm

2 stops10h 51m

Moline Quad-City

Sat 2/14

12:21 pm-11:21 pm

2 stops10h 00m

$320

SyracuseDes Moines

SYR - DSM

SYRDSM

Syracuse Hancock Intl

Fri 4/24

5:12 pm-9:53 pm

1 stop5h 41m

Des Moines

Sun 4/26

6:00 am-11:06 am

1 stop4h 06m

$357

SyracuseOmaha

SYR - OMA

SYROMA

Syracuse Hancock Intl

Thu 2/12

12:55 pm-9:59 pm

2 stops10h 04m

Omaha Eppley Airfield

Mon 2/16

1:50 pm-11:07 pm

1 stop8h 17m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 28 results
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Best time to book a flight from Syracuse to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Iowa

What is the cheapest month to book a flight from Syracuse to Iowa?

Currently, April is the cheapest month in which you can book a flight from Syracuse to Iowa (average of $190). Flying from Syracuse to Iowa in March is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to Iowa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,215 reviews
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Iowa?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Iowa from Syracuse.

  • How long is the flight from Syracuse to Iowa?

    For as low as $271, Delta can have you in Iowa from Syracuse in 5h 19m. Airlines will cover a distance of 901 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Syracuse to Iowa?

    Most travelers choose Syracuse Hancock Intl - Omaha Eppley Airfield, Syracuse Hancock Intl - Des Moines or Syracuse Hancock Intl - Moline Quad-City when deciding on the best route from Syracuse to Iowa.

  • Can I find deals for flights from Syracuse to Iowa that include hotel bookings?

    Yes. In addition to deals on Syracuse to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Iowa.

  • Can I find deals for business class flights from Syracuse to Iowa?

    Yes. Cheapflights offers flight deals from Syracuse to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Iowa?

    Currently, April is the cheapest month in which you can book a flight from Syracuse to Iowa (average of $190). Flying from Syracuse to Iowa in March is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to Iowa

Discover the top 3 airlines that operate flights from Syracuse to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$206Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$368FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$273Average$342FlexibilityNo cancel feeOn-time69%

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