Iowa

$174+ Cheap flights from Myrtle Beach (MYR) to Iowa

MYR — DSM
Dec 11 — Dec 181
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Cheap flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa

Tue 12/811:26 am -
1 stop6h 23m
Tue 12/152:58 pm -
1 stop6h 49m
Deal found 11/10$357
Mon 12/711:26 am -
1 stop6h 23m
Wed 12/95:20 am -
1 stop7h 13m
Deal found 11/9$362
Tue 12/83:25 pm -
2 stops7h 40m
Tue 12/157:00 am -
2 stops11h 25m
Deal found 11/10$373
Tue 12/86:12 am -
1 stop5h 08m
Tue 12/156:05 am -
2 stops9h 32m
Deal found 11/10$382
Mon 12/73:25 pm -
2 stops7h 40m
Wed 12/97:00 am -
2 stops11h 25m
Deal found 11/9$418
Thu 11/127:00 am -
1 stop7h 09m
Sat 11/143:17 pm -
1 stop4h 48m
Deal found 11/9$430
Mon 12/71:54 pm -
2 stops10h 06m
Wed 12/93:31 pm -
1 stop6h 12m
Deal found 11/9$431
Mon 12/143:25 pm -
2 stops7h 40m
Sat 12/195:20 am -
2 stops12h 10m
Deal found 11/9$466
Fri 12/188:09 pm -
1 stop4h 40m
Wed 12/306:07 am -
1 stop5h 08m
Deal found 11/9$547
Mon 12/145:17 pm -
1 stop7h 13m
Sat 12/199:40 am -
2 stops13h 15m
Deal found 11/9$597
Wed 11/258:44 pm -
1 stop4h 14m
Sun 11/296:00 am -
1 stop5h 12m
Deal found 11/9$674
Tue 12/811:30 am -
3 stops10h 55m
Tue 12/158:00 am -
2 stops8h 34m
Deal found 11/10$725

Find flight deals from Myrtle Beach to Iowa

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$357
(Delta)

One-way from

$174
(American Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
From Myrtle Beach Intl to Iowa
One-way flight from Myrtle Beach Intl to Iowa

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sat 1/9

8:15 am-7:25 pm

2 stops12h 10m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$179
Quickest round-trip

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sun 1/10

6:12 am-10:58 am

1 stop5h 46m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$224

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sat 1/9

9:18 pm-1:07 pm

3 stops40h 49m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$267

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sun 1/10

10:48 am-1:07 pm

3 stops27h 19m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$289

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Tue 12/8

3:25 pm-10:05 pm

2 stops7h 40m

Des Moines

Tue 12/15

7:00 am-7:25 pm

2 stops11h 25m

$373

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Tue 12/8

6:12 am-10:20 am

1 stop5h 08m

Des Moines

Tue 12/15

6:05 am-4:37 pm

2 stops9h 32m

$382

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Mon 12/7

3:25 pm-10:05 pm

2 stops7h 40m

Des Moines

Wed 12/9

7:00 am-7:25 pm

2 stops11h 25m

$418

Myrtle BeachCedar Rapids

MYR Myrtle Beach Intl - CID Cedar Rapids

MYRCID

Myrtle Beach Intl

Thu 1/21

11:27 am-6:06 pm

2 stops7h 39m

Cedar Rapids

Sun 1/24

5:00 am-5:48 pm

2 stops11h 48m

$479

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Thu 1/21

11:27 am-9:23 pm

2 stops10h 56m

Des Moines

Mon 1/25

8:00 am-5:48 pm

2 stops8h 48m

$487

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Thu 1/7

11:27 am-11:14 pm

2 stops12h 47m

Des Moines

Mon 1/11

8:00 am-5:48 pm

2 stops8h 48m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Iowa

See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

7.9

Food

6.4

Overall

7.0

Comfort

7.1

Entertainment

6.8

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Crew

7.9

Food

6.4

Overall

7.0

Comfort

7.1

Entertainment

6.8

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like Southwest, American Airlines, and United Airlines fly from Myrtle Beach to Iowa in about 5h 08m. The time it takes to get you to your destination can typically vary by up to 2h 32m. The distance from Myrtle Beach to Iowa is about 969 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Myrtle Beach to Iowa

Top airline flying from Myrtle Beach to Iowa

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$312Average$376FlexibilityNo cancel feeOn-time71%

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