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$194+ Cheap flights from Myrtle Beach (MYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:55 pm
MYR
-
MLI
1 stop4h 29m
Delta
Mon 3/25:01 pm
MLI
-
MYR
1 stop5h 56m
Delta
Deal found 2/1$269
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:10 am
MYR
-
MLI
2 stops8h 50m
American Airlines
Sun 3/17:00 am
MLI
-
MYR
1 stop6h 27m
American Airlines
Deal found 2/1$309
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:54 pm
MYR
-
MLI
1 stop4h 36m
Delta
Sat 3/145:15 pm
MLI
-
MYR
1 stop5h 49m
Delta
Deal found 2/2$331
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2710:31 am
MYR
-
MLI
1 stop6h 45m
Delta
Mon 3/25:01 pm
MLI
-
MYR
1 stop5h 56m
Delta
Deal found 2/1$334
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:38 pm
MYR
-
CID
1 stop7h 06m
American Airlines
Sat 2/214:48 pm
CID
-
MYR
1 stop5h 02m
American Airlines
Deal found 2/2$339
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:23 pm
MYR
-
MLI
1 stop4h 35m
American Airlines
Mon 3/21:30 pm
MLI
-
MYR
2 stops9h 25m
American Airlines
Deal found 2/1$344
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:52 pm
MYR
-
OMA
1 stop7h 40m
American Airlines
Sat 5/165:07 pm
OMA
-
MYR
1 stop4h 15m
American Airlines
Deal found 2/1$359
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
MYR
-
MLI
1 stop7h 11m
American Airlines
Sun 3/11:36 pm
MLI
-
MYR
2 stops9h 19m
American Airlines
Deal found 2/1$379
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:18 pm
MYR
-
CID
1 stop6h 41m
American Airlines
Mon 3/26:36 am
CID
-
MYR
1 stop6h 51m
American Airlines
Deal found 2/1$379
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:14 am
MYR
-
OMA
1 stop5h 46m
American Airlines
Sat 5/165:07 pm
OMA
-
MYR
1 stop4h 15m
American Airlines
Deal found 2/1$383
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:45 pm
MYR
-
DSM
1 stop8h 10m
Delta
Mon 10/56:30 pm
DSM
-
MYR
1 stop4h 09m
Delta
Deal found 2/2$387
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:10 am
MYR
-
DSM
2 stops7h 32m
Delta
Mon 10/56:30 pm
DSM
-
MYR
1 stop4h 09m
Delta
Deal found 2/2$392

Find flight deals from Myrtle Beach to Iowa

Keep the following information in mind while searching for Myrtle Beach to Iowa flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$194
(United Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
Search Deals
From Myrtle Beach Intl to Iowa
Search Deals
One-way flight from Myrtle Beach Intl to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Myrtle Beach

Fly to

Iowa

Route

Depart

Return

Price

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 2/26

6:55 pm-10:24 pm

1 stop4h 29m

Moline Quad-City

Sun 3/1

5:01 pm-11:57 pm

1 stop5h 56m

$269

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 2/26

6:55 pm-10:24 pm

1 stop4h 29m

Moline Quad-City

Mon 3/2

5:01 pm-11:57 pm

1 stop5h 56m

$269

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Tue 3/10

6:54 pm-10:30 pm

1 stop4h 36m

Moline Quad-City

Sat 3/14

5:15 pm-12:04 am

1 stop5h 49m

$331

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Fri 2/27

10:31 am-4:16 pm

1 stop6h 45m

Moline Quad-City

Sun 3/1

5:01 pm-11:57 pm

1 stop5h 56m

$334

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Fri 2/27

10:31 am-4:16 pm

1 stop6h 45m

Moline Quad-City

Mon 3/2

5:01 pm-11:57 pm

1 stop5h 56m

$334

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Tue 2/17

5:38 pm-11:44 pm

1 stop7h 06m

Cedar Rapids

Sat 2/21

4:48 pm-10:50 pm

1 stop5h 02m

$339

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 2/26

6:23 pm-9:58 pm

1 stop4h 35m

Moline Quad-City

Mon 3/2

1:30 pm-11:55 pm

2 stops9h 25m

$344

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Fri 2/27

5:18 pm-10:53 pm

1 stop6h 35m

Moline Quad-City

Mon 3/2

1:30 pm-10:28 pm

2 stops7h 58m

$344

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/12

10:33 am-3:34 pm

1 stop6h 01m

Omaha Eppley Airfield

Wed 5/20

5:07 pm-10:24 pm

1 stop4h 17m

$359

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Sat 5/9

4:52 pm-11:32 pm

1 stop7h 40m

Omaha Eppley Airfield

Sat 5/16

5:07 pm-10:22 pm

1 stop4h 15m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 32 results
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Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

What is the cheapest month to book a flight from Myrtle Beach to Iowa?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated February 3, 2026.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,216 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Food

6.4

Boarding

7.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,216 reviews
American Airlines
7.2
Good
11,216 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Food

6.4

Boarding

7.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like Delta and American Airlines fly from Myrtle Beach to Iowa in about 4h 29m. The time it takes to get you to your destination can typically vary by up to 2h 37m. The distance from Myrtle Beach to Iowa is about 829 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

    The most popular flight routes from Myrtle Beach to Iowa are Myrtle Beach Intl - Omaha Eppley Airfield, Myrtle Beach Intl - Des Moines and Myrtle Beach Intl - Cedar Rapids.

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Iowa

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Top airline flying from Myrtle Beach to Iowa

Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$389FlexibilityNo cancel feeOn-time71%

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