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$194+ Cheap flights from Myrtle Beach (MYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:28 pm
MYR
-
DSM
1 stop28h 38m
Multiple Airlines
Mon 4/139:07 pm
DSM
-
MYR
2 stops19h 26m
Multiple Airlines
Deal found 2/17$290
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:36 pm
MYR
-
OMA
1 stop12h 23m
American Airlines
Sat 5/162:42 pm
OMA
-
MYR
1 stop6h 40m
American Airlines
Deal found 2/15$302
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:14 pm
MYR
-
OMA
1 stop7h 19m
United Airlines
Wed 5/136:00 am
OMA
-
MYR
1 stop7h 18m
United Airlines
Deal found 2/17$305
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:30 pm
MYR
-
OMA
1 stop5h 45m
American Airlines
Wed 5/135:07 pm
OMA
-
MYR
1 stop5h 50m
American Airlines
Deal found 2/16$311
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:15 pm
MYR
-
DSM
1 stop7h 12m
United Airlines
Mon 4/136:20 am
DSM
-
MYR
1 stop6h 57m
United Airlines
Deal found 2/17$329
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:55 pm
MYR
-
MLI
1 stop4h 29m
Delta
Mon 3/25:01 pm
MLI
-
MYR
1 stop5h 56m
Delta
Deal found 2/18$339
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:05 pm
MYR
-
DSM
2 stops7h 05m
Southwest
Mon 4/135:25 am
DSM
-
MYR
2 stops8h 45m
Southwest
Deal found 2/17$339
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:18 pm
MYR
-
MLI
1 stop6h 35m
American Airlines
Mon 3/21:30 pm
MLI
-
MYR
2 stops9h 25m
American Airlines
Deal found 2/18$344
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:19 pm
MYR
-
OMA
1 stop6h 40m
American Airlines
Fri 4/35:17 pm
OMA
-
MYR
1 stop4h 11m
American Airlines
Deal found 2/18$356
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/164:52 pm
MYR
-
CID
1 stop8h 06m
American Airlines
Sat 5/231:21 pm
CID
-
MYR
2 stops9h 29m
American Airlines
Deal found 2/17$359
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:14 am
MYR
-
OMA
2 stops8h 18m
American Airlines
Wed 5/205:07 pm
OMA
-
MYR
1 stop5h 50m
American Airlines
Deal found 2/17$363
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:53 am
MYR
-
DSM
1 stop29h 07m
Multiple Airlines
Sun 5/317:30 am
DSM
-
MYR
1 stop10h 25m
Multiple Airlines
Deal found 2/17$364

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Myrtle Beach

Fly to

Iowa

Route

Depart

Return

Price

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Wed 4/8

6:28 pm-10:06 pm

1 stop28h 38m

Des Moines

Mon 4/13

9:07 pm-5:33 pm

2 stops19h 26m

$290

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Sat 5/9

12:36 pm-11:59 pm

1 stop12h 23m

Omaha Eppley Airfield

Sat 5/16

2:42 pm-10:22 pm

1 stop6h 40m

$302

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/5

3:14 pm-9:33 pm

1 stop7h 19m

Omaha Eppley Airfield

Wed 5/13

6:00 am-2:18 pm

1 stop7h 18m

$305

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/5

6:00 am-10:43 am

1 stop5h 43m

Omaha Eppley Airfield

Wed 5/13

11:11 am-4:43 pm

1 stop4h 32m

$305

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/12

6:30 pm-11:15 pm

1 stop5h 45m

Omaha Eppley Airfield

Wed 5/20

5:07 pm-11:57 pm

1 stop5h 50m

$305

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Wed 4/8

3:15 pm-10:06 pm

1 stop7h 51m

Omaha Eppley Airfield

Tue 4/14

6:00 am-2:17 pm

1 stop7h 17m

$305

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 2/26

6:55 pm-10:24 pm

1 stop4h 29m

Moline Quad-City

Mon 3/2

5:01 pm-11:57 pm

1 stop5h 56m

$309

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/5

6:30 pm-11:15 pm

1 stop5h 45m

Omaha Eppley Airfield

Wed 5/13

5:07 pm-11:57 pm

1 stop5h 50m

$311

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 2/26

3:17 pm-9:58 pm

1 stop7h 41m

Moline Quad-City

Mon 3/2

1:30 pm-10:28 pm

2 stops7h 58m

$314

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Wed 4/8

3:15 pm-9:27 pm

1 stop7h 12m

Des Moines

Mon 4/13

6:20 am-2:17 pm

1 stop6h 57m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Showing 1-10 of 26 results
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Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

What is the cheapest month to book a flight from Myrtle Beach to Iowa?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in February is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated February 18, 2026.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,304 reviews

Food

6.4

Comfort

7.2

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,304 reviews
American Airlines
7.2
Good
11,304 reviews

Food

6.4

Comfort

7.2

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like American Airlines, United Airlines, and Delta fly from Myrtle Beach to Iowa in about 5h 43m. The time it takes to get you to your destination can typically vary by up to 6h 40m. The distance from Myrtle Beach to Iowa is about 1066 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

    The most popular flight routes from Myrtle Beach to Iowa are Myrtle Beach Intl - Omaha Eppley Airfield, Myrtle Beach Intl - Des Moines and Myrtle Beach Intl - Moline Quad-City.

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in February is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Myrtle Beach to Iowa

Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$389FlexibilityNo cancel feeOn-time71%

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