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$192+ Cheap flights from Myrtle Beach (MYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
MYR
-
MLI
1 stop5h 26m
Delta
Tue 6/235:00 pm
MLI
-
MYR
1 stop5h 38m
Delta
Deal found 3/9$289
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:17 pm
MYR
-
CID
1 stop6h 46m
American Airlines
Tue 6/236:00 am
CID
-
MYR
1 stop4h 51m
American Airlines
Deal found 3/9$289
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:54 pm
MYR
-
MLI
1 stop4h 36m
Delta
Tue 3/315:15 pm
MLI
-
MYR
1 stop5h 49m
Delta
Deal found 3/8$294
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:54 pm
MYR
-
MLI
1 stop4h 36m
Delta
Sat 3/285:15 pm
MLI
-
MYR
1 stop5h 49m
Delta
Deal found 3/8$299
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:10 am
MYR
-
CID
2 stops8h 27m
American Airlines
Mon 3/306:36 am
CID
-
MYR
1 stop6h 51m
American Airlines
Deal found 3/9$299
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:14 pm
MYR
-
OMA
1 stop7h 24m
United Airlines
Wed 5/138:01 am
OMA
-
MYR
1 stop5h 17m
United Airlines
Deal found 3/10$305
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:28 pm
MYR
-
CID
1 stop24h 39m
Multiple Airlines
Mon 3/306:57 pm
CID
-
MYR
1 stop21h 36m
Multiple Airlines
Deal found 3/9$308
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:14 am
MYR
-
OMA
2 stops7h 18m
American Airlines
Tue 5/193:24 pm
OMA
-
MYR
1 stop6h 38m
American Airlines
Deal found 3/10$310
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:19 pm
MYR
-
OMA
2 stops7h 46m
American Airlines
Wed 5/135:07 pm
OMA
-
MYR
1 stop4h 17m
American Airlines
Deal found 3/11$316
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:08 pm
MYR
-
DSM
1 stop7h 32m
United Airlines
Tue 6/96:00 am
DSM
-
MYR
1 stop7h 12m
United Airlines
Deal found 3/10$319
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:19 pm
MYR
-
CID
1 stop6h 40m
American Airlines
Mon 3/304:48 pm
CID
-
MYR
1 stop6h 07m
American Airlines
Deal found 3/11$319
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:34 am
MYR
-
MLI
2 stops11h 40m
United Airlines
Tue 6/238:10 am
MLI
-
MYR
1 stop5h 02m
United Airlines
Deal found 3/9$321

Find flight deals from Myrtle Beach to Iowa

Keep the following information in mind while searching for Myrtle Beach to Iowa flight deals. Data was last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(Delta)

One-way from

$192
(Southwest)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
Search Deals
From Myrtle Beach Intl to Iowa
Search Deals
One-way flight from Myrtle Beach Intl to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Tue 6/16

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Tue 6/23

5:00 pm-11:38 pm

1 stop5h 38m

$289

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Wed 4/22

7:02 pm-11:12 pm

1 stop5h 10m

Cedar Rapids

Sun 4/26

6:45 am-3:06 pm

1 stop7h 21m

$289

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Tue 6/16

4:17 pm-11:21 pm

2 stops8h 04m

Cedar Rapids

Tue 6/23

6:00 am-11:51 am

1 stop4h 51m

$294

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 3/26

6:54 pm-10:30 pm

1 stop4h 36m

Moline Quad-City

Mon 3/30

5:15 pm-12:04 am

1 stop5h 49m

$294

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Wed 5/27

3:08 pm-9:40 pm

1 stop7h 32m

Des Moines

Tue 6/9

6:00 am-2:12 pm

1 stop7h 12m

$319

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Tue 6/16

10:34 am-9:14 pm

2 stops11h 40m

Moline Quad-City

Tue 6/23

8:10 am-2:12 pm

1 stop5h 02m

$321

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Wed 4/15

11:00 am-3:39 pm

1 stop5h 39m

Omaha Eppley Airfield

Sat 4/18

8:00 am-2:17 pm

1 stop5h 17m

$321

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/5

12:19 pm-7:05 pm

2 stops7h 46m

Omaha Eppley Airfield

Wed 5/13

5:07 pm-10:24 pm

1 stop4h 17m

$323

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Sat 5/9

9:19 am-7:05 pm

2 stops10h 46m

Omaha Eppley Airfield

Tue 5/19

4:19 pm-11:02 pm

1 stop5h 43m

$334

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Tue 5/5

3:14 pm-9:38 pm

1 stop7h 24m

Omaha Eppley Airfield

Wed 5/13

6:00 am-2:18 pm

1 stop7h 18m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 27 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

What is the cheapest month to book a flight from Myrtle Beach to Iowa?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in February is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 13, 2026.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,446 reviews

Comfort

7.2

Food

6.4

Overall

7.1

Boarding

7.5

Crew

7.9

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,446 reviews
American Airlines
7.1
Good
11,446 reviews

Comfort

7.2

Food

6.4

Overall

7.1

Boarding

7.5

Crew

7.9

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like Delta, American Airlines, and United Airlines fly from Myrtle Beach to Iowa in about 5h 26m. The time it takes to get you to your destination can typically vary by up to 2h 38m. The distance from Myrtle Beach to Iowa is about 829 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

    The most popular flight routes from Myrtle Beach to Iowa are Myrtle Beach Intl - Des Moines, Myrtle Beach Intl - Omaha Eppley Airfield and Myrtle Beach Intl - Cedar Rapids.

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in February is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Myrtle Beach to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Myrtle Beach to Iowa

Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$392FlexibilityNo cancel feeOn-time71%

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