$147+ Cheap flights from Myrtle Beach (MYR) to Iowa
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
Oct 25 — Nov 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to Iowa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Iowa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to IowaExplore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:36 am -
2 stops37h 39m
Thu 11/124:15 pm -
1 stop14h 48m
Deal found 9/24![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:58 pm -
2 stops30h 12m
Thu 10/225:52 pm -
1 stop13h 11m
Deal found 9/24![Multiple Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:10 am -
1 stop6h 38m
Thu 11/127:06 am -
1 stop4h 10m
Deal found 9/24![American Airlines logo]()
$421
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:00 pm -
2 stops8h 24m
Sun 9/277:55 am -
1 stop6h 21m
Deal found 9/22![United Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:10 pm -
2 stops8h 51m
Mon 9/281:35 pm -
2 stops6h 33m
Deal found 9/22![American Airlines logo]()
$438
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:40 pm -
2 stops10h 25m
Thu 11/125:25 am -
2 stops13h 55m
Deal found 9/24![Southwest logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:00 pm -
1 stop6h 47m
Mon 9/286:30 am -
1 stop7h 46m
Deal found 9/20![United Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:34 am -
2 stops11h 19m
Mon 9/2812:10 pm -
2 stops10h 18m
Deal found 9/21![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:13 am -
2 stops10h 11m
Sat 10/101:53 pm -
2 stops7h 49m
Deal found 9/21![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:27 am -
2 stops13h 15m
Mon 11/95:09 pm -
2 stops16h 12m
Deal found 9/22![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:27 am -
2 stops13h 15m
Thu 11/128:00 am -
3 stops25h 21m
Deal found 9/24![United Airlines logo]()
$784
Best flights from Myrtle Beach to IowaDiscover carefully curated flight deals from Myrtle Beach to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
Discover carefully curated flight deals from Myrtle Beach to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:06 pm -
1 stop7h 34m
Sun 1/2410:26 am -
2 stops9h 29m
Deal found 9/23![American Airlines logo]()
$376
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/311:28 am -
2 stops8h 45m
Sat 2/66:00 am -
2 stops9h 49m
Deal found 9/22![United Airlines logo]()
$401
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:40 pm -
2 stops10h 25m
Thu 11/125:25 am -
2 stops13h 55m
Deal found 9/24![Southwest logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 pm -
1 stop6h 47m
Mon 10/127:55 am -
1 stop6h 21m
Deal found 9/23![United Airlines logo]()
$572
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:10 pm -
1 stop5h 58m
Sat 10/107:00 am -
1 stop5h 31m
Deal found 9/21![American Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:27 am -
2 stops13h 15m
Mon 11/95:09 pm -
2 stops16h 12m
Deal found 9/22![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2111:28 am -
3 stops12h 48m
Sun 1/248:00 am -
2 stops7h 49m
Deal found 9/23![United Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:27 am -
2 stops13h 15m
Thu 11/128:00 am -
3 stops25h 21m
Deal found 9/24![United Airlines logo]()
$784
Last-minute flights from Myrtle Beach to IowaDiscover last-minute flight deals from Myrtle Beach to Iowa. Data last updated September 25, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Iowa. Data last updated September 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:10 pm -
2 stops8h 51m
Mon 9/281:35 pm -
2 stops6h 33m
Deal found 9/22![American Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:00 pm -
1 stop6h 47m
Mon 9/286:30 am -
1 stop7h 46m
Deal found 9/20![United Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:34 am -
2 stops11h 19m
Mon 9/2812:10 pm -
2 stops10h 18m
Deal found 9/21![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:13 am -
2 stops10h 11m
Sat 10/101:53 pm -
2 stops7h 49m
Deal found 9/21![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 pm -
1 stop6h 47m
Mon 10/127:55 am -
1 stop6h 21m
Deal found 9/23![United Airlines logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:58 pm -
2 stops30h 12m
Thu 10/225:52 pm -
1 stop13h 11m
Deal found 9/24![Multiple Airlines logo]()
$400
One-way flights from Myrtle Beach to IowaSearch for one-way flight options from Myrtle Beach to Iowa. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
Search for one-way flight options from Myrtle Beach to Iowa. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:32 am -
1 stop6h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$147
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:12 pm -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$163
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:38 am -
2 stops11h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$168
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:23 am -
2 stops12h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:45 am -
3 stops50h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:10 pm -
1 stop5h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:42 pm -
3 stops44h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$421
Find flight deals from Myrtle Beach to Iowa
Keep the following information in mind while searching for Myrtle Beach to Iowa flight deals. Data was last updated September 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $336 (Kiwi.com) |
One-way from | $147 (Kiwi.com) |
Popular in | July |
Cheapest in | February |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachDes Moines
MYR Myrtle Beach Intl - DSM Des Moines
MYRDSM
Myrtle Beach Intl
Thu 10/22
9:32 am-2:42 pm
1 stop6h 10m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Quickest round-trip
Myrtle BeachDes Moines
MYR Myrtle Beach Intl - DSM Des Moines
MYRDSM
Myrtle Beach Intl
Sat 10/17
8:12 pm-11:58 pm
1 stop4h 46m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$163
Myrtle BeachDes Moines
MYR Myrtle Beach Intl - DSM Des Moines
MYRDSM
Myrtle Beach Intl
Sat 10/17
10:38 am-9:23 pm
2 stops11h 45m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$168
Myrtle BeachCedar Rapids
MYR Myrtle Beach Intl - CID Cedar Rapids
MYRCID
Myrtle Beach Intl
Tue 10/6
10:23 am-9:29 pm
2 stops12h 06m
Cedar Rapids
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$324
Myrtle BeachDes Moines
MYR Myrtle Beach Intl - DSM Des Moines
MYRDSM
Myrtle Beach Intl
Thu 1/21
5:06 pm-11:40 pm
1 stop7h 34m
Des Moines
Sun 1/24
10:26 am-8:55 pm
2 stops9h 29m
$376
Myrtle BeachCedar Rapids
MYR Myrtle Beach Intl - CID Cedar Rapids
MYRCID
Myrtle Beach Intl
Wed 2/3
11:28 am-7:13 pm
2 stops8h 45m
Cedar Rapids
Sat 2/6
6:00 am-4:49 pm
2 stops9h 49m
$401
Myrtle BeachCedar Rapids
MYR Myrtle Beach Intl - CID Cedar Rapids
MYRCID
Myrtle Beach Intl
Tue 10/6
2:10 pm-7:08 pm
1 stop5h 58m
Cedar Rapids
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$403
Myrtle BeachDes Moines
MYR Myrtle Beach Intl - DSM Des Moines
MYRDSM
Myrtle Beach Intl
Sat 10/17
2:42 pm-10:27 am
3 stops44h 45m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$421
Myrtle BeachDes Moines
MYR Myrtle Beach Intl - DSM Des Moines
MYRDSM
Myrtle Beach Intl
Thu 11/5
1:40 pm-11:05 pm
2 stops10h 25m
Des Moines
Thu 11/12
5:25 am-8:20 pm
2 stops13h 55m
$453
Myrtle BeachCedar Rapids
MYR Myrtle Beach Intl - CID Cedar Rapids
MYRCID
Myrtle Beach Intl
Thu 10/8
5:00 pm-10:47 pm
1 stop6h 47m
Cedar Rapids
Mon 10/12
7:55 am-3:16 pm
1 stop6h 21m
$572
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Myrtle Beach to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
MYR-DSM
MYR-CID
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Iowa
MYR-USIA
MYR-DSM
MYR-CID
How much does it cost to fly round-trip from Myrtle Beach to Iowa?
Airfare is below average for this route at the moment.
Myrtle Beach to Iowa flights typically cost between $340 and $504 in November.The cheapest round-trip price found within the last 5 days was $336 on Multiple Airlines (Nov 5-Nov 12).
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated September 25, 2026.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Entertainment
6.8
Food
6.4
Boarding
7.4
Crew
7.9
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Comfort
7.2
Entertainment
6.8
Food
6.4
Boarding
7.4
Crew
7.9
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Myrtle Beach to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Myrtle Beach to Iowa by cabin class
Find flights from Myrtle Beach to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and Iowa flights
Browse other Myrtle Beach and Iowa flight options. Last updated on September 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Myrtle Beach to Iowa flights
Consider these flights traveling from Myrtle Beach to Iowa.
Top airline flying from Myrtle Beach to Iowa
Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$294 | Average$419 | FlexibilityNo cancel fee | On-time71% |