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$206+ Cheap flights from Myrtle Beach (MYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Iowa

Keep the following information in mind while searching for Myrtle Beach to Iowa flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$206
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$298
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
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From Myrtle Beach Intl to Iowa
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One-way flight from Myrtle Beach Intl to Iowa
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Highest demand for flights based on searches. 15% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 pmMYR - MLI
1 stop6h 18mDelta
Tue 1/65:06 pmMLI - MYR
1 stop5h 37mDelta
Deal found 11/5$249
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amMYR - MLI
2 stops9h 05mAmerican Airlines
Tue 1/611:28 amMLI - MYR
2 stops10h 47mAmerican Airlines
Deal found 11/5$259
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/252:46 pmMYR - DSM
1 stop9h 38mMultiple Airlines
Mon 12/16:53 pmDSM - MYR
1 stop28h 01mMultiple Airlines
Deal found 11/5$269
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:40 amMYR - DSM
2 stops27h 51mMultiple Airlines
Mon 12/16:53 pmDSM - MYR
1 stop28h 01mMultiple Airlines
Deal found 11/5$276
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:15 amMYR - DSM
1 stop11h 25mMultiple Airlines
Mon 12/16:53 pmDSM - MYR
1 stop28h 01mMultiple Airlines
Deal found 11/5$282
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/252:46 pmMYR - DSM
1 stop9h 38mMultiple Airlines
Fri 11/2810:00 amDSM - MYR
1 stop9h 03mMultiple Airlines
Deal found 11/5$289
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:59 pmMYR - DSM
1 stop16h 56mMultiple Airlines
Mon 12/16:53 pmDSM - MYR
1 stop28h 01mMultiple Airlines
Deal found 11/5$291
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:56 pmMYR - MLI
1 stop4h 37mDelta
Sat 12/65:08 pmMLI - MYR
1 stop5h 35mDelta
Deal found 11/4$294
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:40 amMYR - DSM
2 stops27h 51mMultiple Airlines
Fri 11/2810:00 amDSM - MYR
1 stop9h 03mMultiple Airlines
Deal found 11/5$296
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/239:35 pmMYR - DSM
2 stops24h 34mMultiple Airlines
Mon 12/16:53 pmDSM - MYR
1 stop28h 01mMultiple Airlines
Deal found 11/5$297
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:41 pmMYR - MLI
1 stop6h 33mAmerican Airlines
Sat 12/610:52 amMLI - MYR
2 stops12h 02mAmerican Airlines
Deal found 11/4$299
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:15 amMYR - DSM
1 stop11h 25mMultiple Airlines
Fri 11/2810:00 amDSM - MYR
1 stop9h 03mMultiple Airlines
Deal found 11/5$302

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Myrtle Beach

Fly to

Iowa

Route

Depart

Return

Price

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Wed 12/31

5:12 pm-10:30 pm

1 stop6h 18m

Moline Quad-City

Tue 1/6

5:06 pm-11:43 pm

1 stop5h 37m

$249

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Wed 12/31

2:53 pm-8:52 pm

1 stop6h 59m

Moline Quad-City

Tue 1/6

7:31 am-6:49 pm

2 stops10h 18m

$249

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Sat 4/4

6:45 pm-10:34 pm

1 stop4h 49m

Moline Quad-City

Tue 4/7

5:00 pm-11:35 pm

1 stop5h 35m

$279

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Tue 11/25

2:46 pm-11:24 pm

1 stop9h 38m

Des Moines

Fri 11/28

10:00 am-8:03 pm

1 stop9h 03m

$289

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Tue 12/2

6:56 pm-10:33 pm

1 stop4h 37m

Moline Quad-City

Sat 12/6

5:08 pm-11:43 pm

1 stop5h 35m

$294

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Mon 11/24

10:40 am-1:31 pm

2 stops27h 51m

Des Moines

Fri 11/28

10:00 am-8:03 pm

1 stop9h 03m

$296

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Tue 12/2

5:41 pm-11:14 pm

1 stop6h 33m

Moline Quad-City

Sat 12/6

10:52 am-11:54 pm

2 stops12h 02m

$299

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Tue 11/25

2:46 pm-11:24 pm

1 stop9h 38m

Des Moines

Thu 11/27

7:30 am-8:03 pm

1 stop11h 33m

$302

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Sat 11/22

9:15 am-8:29 am

1 stop24h 14m

Des Moines

Thu 11/27

7:30 am-8:03 pm

1 stop11h 33m

$336

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Wed 11/26

5:21 pm-11:35 pm

1 stop7h 14m

Cedar Rapids

Mon 12/1

6:35 am-1:59 pm

1 stop6h 24m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 36 results
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Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

What is the cheapest month to book a flight from Myrtle Beach to Iowa?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IA?

Find hourly flight availability from Myrtle Beach to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Iowa is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 22% on airfare.

How much does it cost to fly round-trip from Myrtle Beach to Iowa?

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 5, 2025.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,042 reviews

Entertainment

6.9

Crew

8.0

Comfort

7.2

Boarding

7.5

Food

6.4

Overall

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,042 reviews
American Airlines
7.2
Good
11,042 reviews

Entertainment

6.9

Crew

8.0

Comfort

7.2

Boarding

7.5

Food

6.4

Overall

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like Delta and American Airlines fly from Myrtle Beach to Iowa in about 6h 18m. The time it takes to get you to your destination can typically vary by up to 41m. The distance from Myrtle Beach to Iowa is about 829 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Iowa one-way?

    The cheapest airlines for a one-way flight from Myrtle Beach to Iowa are Allegiant Air ($206), Delta ($209), and American Airlines ($214).

  • What are the most popular routes from Myrtle Beach to Iowa?

    The most popular flight routes from Myrtle Beach to Iowa are Myrtle Beach Intl - Des Moines, Myrtle Beach Intl - Omaha Eppley Airfield and Myrtle Beach Intl - Moline Quad-City.

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Myrtle Beach to Iowa

Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$389FlexibilityNo cancel feeOn-time71%

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