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$148+ Cheap flights from Myrtle Beach (MYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
feb. 5 — feb. 121
jue. 2/5
jue. 2/12
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Iowa

Keep the following information in mind while searching for Myrtle Beach to Iowa flight deals. Data was last updated enero 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(Delta)

One-way from

$148
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
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From Myrtle Beach Intl to Iowa
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One-way flight from Myrtle Beach Intl to Iowa
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Find flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 6, 2026.

This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/1612:21 pmMYR - CID
1 stop6h 53mAmerican Airlines
lun. 7/206:00 amCID - MYR
1 stop4h 48mAmerican Airlines
Deal found 1/4$289
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/106:00 amMYR - OMA
1 stop5h 35mDelta
mié. 3/186:05 amOMA - MYR
1 stop5h 00mDelta
Deal found 1/6$299
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/1010:26 amMYR - OMA
2 stops9h 42mAmerican Airlines
mié. 3/185:17 pmOMA - MYR
1 stop5h 38mAmerican Airlines
Deal found 1/6$304
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/65:29 pmMYR - DSM
1 stop6h 39mAmerican Airlines
mar. 2/106:00 amDSM - MYR
1 stop7h 55mAmerican Airlines
Deal found 1/6$312
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/612:22 pmMYR - DSM
1 stop8h 12mDelta
mar. 2/106:24 amDSM - MYR
2 stops7h 40mDelta
Deal found 1/6$317
This Delta deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/173:40 pmMYR - CID
1 stop7h 10mDelta
lun. 7/207:00 amCID - MYR
1 stop5h 39mDelta
Deal found 1/4$341
This Delta deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/153:40 pmMYR - CID
1 stop7h 10mDelta
lun. 7/207:00 amCID - MYR
1 stop5h 39mDelta
Deal found 1/4$356
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/172:40 pmMYR - DSM
1 stop7h 37mDelta
mar. 6/237:00 amDSM - MYR
1 stop5h 39mDelta
Deal found 1/5$387
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/176:50 amMYR - DSM
1 stop7h 06mAmerican Airlines
mar. 6/238:53 amDSM - MYR
2 stops7h 24mAmerican Airlines
Deal found 1/5$405
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/154:24 pmMYR - CID
2 stops8h 13mAmerican Airlines
lun. 7/206:00 amCID - MYR
1 stop4h 48mAmerican Airlines
Deal found 1/4$447
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/1412:26 pmMYR - MLI
2 stops10h 01mUnited Airlines
mié. 2/186:30 amMLI - MYR
2 stops9h 19mUnited Airlines
Deal found 1/5$514
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/166:07 pmMYR - DSM
1 stop6h 44mAmerican Airlines
lun. 7/201:45 pmDSM - MYR
2 stops6h 58mAmerican Airlines
Deal found 1/5$523

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 6, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Myrtle Beach

Fly to

Iowa

Route

Depart

Return

Price

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

mar. 3/10

10:26 am-7:08 pm

2 stops9h 42m

Omaha Eppley Airfield

mié. 3/18

5:17 pm-11:55 pm

1 stop5h 38m

$304

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

vie. 2/6

5:29 pm-11:08 pm

1 stop6h 39m

Des Moines

mar. 2/10

6:00 am-2:55 pm

1 stop7h 55m

$312

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

vie. 2/6

2:19 pm-8:54 pm

2 stops7h 35m

Des Moines

mar. 2/10

6:24 am-3:04 pm

2 stops7h 40m

$323

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

dom. 1/18

5:29 pm-11:05 pm

1 stop6h 36m

Cedar Rapids

dom. 1/25

6:25 am-11:35 am

1 stop4h 10m

$349

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mié. 6/17

2:40 pm-9:17 pm

1 stop7h 37m

Des Moines

mar. 6/23

7:00 am-1:39 pm

1 stop5h 39m

$387

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mié. 6/17

6:50 am-12:56 pm

1 stop7h 06m

Des Moines

mar. 6/23

6:00 am-12:58 pm

1 stop5h 58m

$387

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

mar. 3/10

6:00 am-10:35 am

1 stop5h 35m

Omaha Eppley Airfield

mié. 3/18

7:02 am-1:31 pm

1 stop5h 29m

$407

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

sáb. 2/14

12:26 pm-9:27 pm

2 stops10h 01m

Moline Quad-City

mié. 2/18

6:30 am-4:49 pm

2 stops9h 19m

$514

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

sáb. 2/14

5:13 pm-9:26 pm

2 stops29h 13m

Cedar Rapids

mié. 2/18

6:35 am-4:49 pm

2 stops9h 14m

$528

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

dom. 3/22

5:18 pm-10:59 pm

1 stop6h 41m

Omaha Eppley Airfield

jue. 3/26

5:17 pm-11:55 pm

1 stop5h 38m

$545

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/4

Showing 1-10 of 21 results
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Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

What is the cheapest month to book a flight from Myrtle Beach to Iowa?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated enero 6, 2026.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,083 reviews

Overall

7.2

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,083 reviews
American Airlines
7.2
Good
11,083 reviews

Overall

7.2

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like American Airlines, Delta, and United Airlines fly from Myrtle Beach to Iowa in about 7h 35m. The time it takes to get you to your destination can typically vary by up to 2h 26m. The distance from Myrtle Beach to Iowa is about 969 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

    The most popular flight routes from Myrtle Beach to Iowa are Myrtle Beach Intl - Des Moines, Myrtle Beach Intl - Cedar Rapids and Myrtle Beach Intl - Moline Quad-City.

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Iowa (average of $162). Flying from Myrtle Beach to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Myrtle Beach to Iowa

Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$389FlexibilityNo cancel feeOn-time71%

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