Iowa

$334+ Cheap flights from Myrtle Beach (MYR) to Iowa

MYR — DSM
Dec 7 — Dec 141
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Cheap flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa

Tue 11/106:58 pm -
1 stop5h 11m
Sat 11/145:15 am -
1 stop3h 52m
Deal found 11/3$397
Fri 11/64:30 pm -
1 stop6h 26m
Mon 11/95:15 am -
1 stop3h 52m
Deal found 11/3$461
Tue 11/106:12 am -
2 stops8h 05m
Sat 11/141:58 pm -
2 stops7h 46m
Deal found 11/2$494
Tue 11/1011:27 am -
2 stops12h 29m
Sat 11/146:00 am -
2 stops10h 11m
Deal found 11/3$507
Thu 11/1910:52 am -
1 stop4h 21m
Mon 11/235:30 am -
1 stop7h 03m
Deal found 11/3$537
Thu 11/195:10 am -
1 stop6h 38m
Mon 11/231:58 pm -
2 stops8h 56m
Deal found 11/3$542
Tue 12/811:30 am -
2 stops12h 15m
Sat 12/126:05 am -
2 stops10h 46m
Deal found 11/3$554
Fri 11/611:03 am -
2 stops7h 36m
Mon 11/93:01 pm -
1 stop4h 56m
Deal found 11/3$566
Fri 11/68:35 pm -
1 stop4h 23m
Sun 11/81:40 pm -
1 stop5h 15m
Deal found 11/3$572
Fri 11/69:51 pm -
2 stops18h 42m
Sun 11/812:25 pm -
1 stop18h 38m
Deal found 11/3$768
Thu 11/1911:27 am -
2 stops12h 32m
Mon 11/233:24 pm -
3 stops17h 57m
Deal found 11/3$921
Fri 11/64:30 pm -
1 stop7h 03m
Sun 11/83:03 pm -
1 stop6h 54m
Deal found 11/3$1,037

Find flight deals from Myrtle Beach to Iowa

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$434
(Delta)

One-way from

$334
(Kiwi.com)

Popular in

July

Cheapest in

February

Average price

$536
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
From Myrtle Beach Intl to Iowa
One-way flight from Myrtle Beach Intl to Iowa
Highest demand for flights based on searches. 13% potential increase in price ($70 potential increase over avg. RT price).
Cheapest flight prices on average. 8% potential price decrease ($36 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Mon 3/22

1:53 pm-11:37 am

1 stop22h 44m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$334

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sun 3/21

1:55 pm-11:15 pm

1 stop10h 20m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$399

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Thu 1/21

11:27 am-9:23 pm

2 stops10h 56m

Des Moines

Mon 1/25

8:00 am-5:48 pm

2 stops8h 48m

$435

Myrtle BeachCedar Rapids

MYR Myrtle Beach Intl - CID Cedar Rapids

MYRCID

Myrtle Beach Intl

Thu 1/21

11:27 am-6:06 pm

2 stops7h 39m

Cedar Rapids

Sun 1/24

5:00 am-5:48 pm

2 stops11h 48m

$479

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sat 3/20

10:34 am-11:03 pm

3 stops13h 29m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$537

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Thu 11/19

10:52 am-2:13 pm

1 stop4h 21m

Des Moines

Mon 11/23

5:30 am-1:33 pm

1 stop7h 03m

$537

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Thu 11/19

5:10 am-1:28 pm

2 stops9h 18m

Des Moines

Mon 11/23

1:58 pm-11:54 pm

2 stops8h 56m

$548

Myrtle BeachCedar Rapids

MYR Myrtle Beach Intl - CID Cedar Rapids

MYRCID

Myrtle Beach Intl

Tue 12/8

11:30 am-10:45 pm

2 stops12h 15m

Cedar Rapids

Sat 12/12

6:05 am-5:51 pm

2 stops10h 46m

$554
Quickest round-trip

Myrtle BeachDes Moines

MYR Myrtle Beach Intl - DSM Des Moines

MYRDSM

Myrtle Beach Intl

Sat 3/20

8:05 pm-11:58 pm

1 stop4h 53m

Des Moines

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$623

Myrtle BeachCedar Rapids

MYR Myrtle Beach Intl - CID Cedar Rapids

MYRCID

Myrtle Beach Intl

Sat 11/21

6:51 pm-11:09 pm

1 stop5h 18m

Cedar Rapids

Wed 11/25

5:15 am-10:07 am

1 stop3h 52m

$686

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Iowa

See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.0

Entertainment

6.8

Crew

7.9

Boarding

7.4

Comfort

7.2

Food

6.4

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Overall

7.0

Entertainment

6.8

Crew

7.9

Boarding

7.4

Comfort

7.2

Food

6.4

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like United Airlines, Delta, and American Airlines fly from Myrtle Beach to Iowa in about 4h 21m. The time it takes to get you to your destination can typically vary by up to 6h 35m. The distance from Myrtle Beach to Iowa is about 969 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Myrtle Beach to Iowa

Top airline flying from Myrtle Beach to Iowa

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$312Average$376FlexibilityNo cancel feeOn-time71%

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