Iowa

$204+ Cheap flights from Myrtle Beach (MYR) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
Jul 27 — Aug 31
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Cheap flight deals from Myrtle Beach to Iowa

Cheapest flights from Myrtle Beach to Iowa
Explore the most affordable flight options available from Myrtle Beach to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.

This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:10 pm
MYR
-
DSM
1 stop5h 31m
American Airlines
Mon 10/56:04 am
DSM
-
MYR
1 stop4h 52m
American Airlines
Deal found 6/26$307
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:16 pm
MYR
-
MLI
1 stop6h 44m
American Airlines
Tue 7/214:20 pm
MLI
-
MYR
1 stop4h 23m
American Airlines
Deal found 6/24$309
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:51 am
MYR
-
DSM
1 stop7h 05m
American Airlines
Tue 7/287:04 am
DSM
-
MYR
1 stop7h 27m
American Airlines
Deal found 6/25$317
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:10 pm
MYR
-
MLI
1 stop4h 50m
American Airlines
Tue 7/214:20 pm
MLI
-
MYR
1 stop4h 23m
American Airlines
Deal found 6/26$324
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/91:06 pm
MYR
-
DSM
2 stops11h 01m
Multiple Airlines
Mon 7/134:40 pm
DSM
-
MYR
1 stop16h 10m
Multiple Airlines
Deal found 6/23$325
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:30 pm
MYR
-
DSM
1 stop4h 22m
American Airlines
Mon 10/56:04 am
DSM
-
MYR
1 stop4h 52m
American Airlines
Deal found 6/24$337
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:16 pm
MYR
-
MLI
1 stop6h 44m
American Airlines
Tue 7/144:20 pm
MLI
-
MYR
1 stop4h 23m
American Airlines
Deal found 6/25$339
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:43 pm
MYR
-
CID
1 stop7h 37m
American Airlines
Sun 7/126:04 am
CID
-
MYR
1 stop5h 18m
American Airlines
Deal found 6/24$339
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:34 am
MYR
-
DSM
2 stops11h 48m
United Airlines
Tue 7/288:00 am
DSM
-
MYR
1 stop5h 19m
United Airlines
Deal found 6/25$344
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:50 pm
MYR
-
DSM
2 stops8h 05m
Southwest
Sat 8/13:35 pm
DSM
-
MYR
1 stop4h 35m
Southwest
Deal found 6/24$353
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:33 pm
MYR
-
OMA
1 stop5h 05m
American Airlines
Thu 8/136:14 am
OMA
-
MYR
1 stop4h 10m
American Airlines
Deal found 6/22$356
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:30 pm
MYR
-
DSM
1 stop4h 22m
American Airlines
Sun 10/411:00 am
DSM
-
MYR
1 stop5h 25m
American Airlines
Deal found 6/26$357

Find flight deals from Myrtle Beach to Iowa

Keep the following information in mind while searching for Myrtle Beach to Iowa flight deals. Data was last updated June 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$307
(American Airlines)

One-way from

$204
(Delta)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
From Myrtle Beach Intl to Iowa
One-way flight from Myrtle Beach Intl to Iowa

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Tue 7/14

6:10 pm-10:00 pm

1 stop4h 50m

Moline Quad-City

Tue 7/21

4:20 pm-9:43 pm

1 stop4h 23m

$309

Myrtle BeachMoline

MYR - MLI

MYRMLI

Myrtle Beach Intl

Thu 7/16

4:16 pm-10:00 pm

1 stop6h 44m

Moline Quad-City

Tue 7/21

4:20 pm-9:43 pm

1 stop4h 23m

$309

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Fri 7/10

4:43 pm-10:03 pm

1 stop6h 20m

Cedar Rapids

Tue 7/14

7:28 am-3:37 pm

1 stop7h 09m

$339

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Fri 7/10

4:43 pm-11:20 pm

1 stop7h 37m

Cedar Rapids

Sun 7/12

6:04 am-12:22 pm

1 stop5h 18m

$339

Myrtle BeachCedar Rapids

MYR - CID

MYRCID

Myrtle Beach Intl

Thu 7/9

6:10 pm-10:03 pm

1 stop4h 53m

Cedar Rapids

Mon 7/13

6:04 am-12:22 pm

1 stop5h 18m

$339

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Wed 7/22

10:34 am-9:22 pm

2 stops11h 48m

Des Moines

Tue 7/28

8:00 am-2:19 pm

1 stop5h 19m

$344

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Mon 8/3

7:15 pm-11:35 pm

1 stop5h 20m

Des Moines

Mon 8/24

5:40 am-2:45 pm

2 stops8h 05m

$363
Quickest round-trip

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Sun 8/16

8:26 pm-11:48 pm

1 stop4h 22m

Des Moines

Thu 8/20

5:10 pm-10:38 pm

1 stop4h 28m

$372

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Thu 10/1

6:15 pm-11:52 pm

1 stop6h 37m

Des Moines

Sun 10/4

6:00 am-3:32 pm

2 stops8h 32m

$377

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

Wed 8/12

10:23 am-5:25 pm

2 stops8h 02m

Omaha Eppley Airfield

Thu 8/13

7:00 pm-9:44 am

2 stops13h 44m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/23

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Myrtle Beach to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Iowa
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated June 27, 2026.
See what other customers who have flown with American Airlines from Myrtle Beach to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.2

Overall

7.1

Boarding

7.5

Crew

7.9

Entertainment

6.8

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Comfort

7.2

Overall

7.1

Boarding

7.5

Crew

7.9

Entertainment

6.8

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Myrtle Beach to Iowa?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Iowa. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Iowa?

    Airlines like American Airlines, United Airlines, and Southwest fly from Myrtle Beach to Iowa in about 4h 50m. The time it takes to get you to your destination can typically vary by up to 6h 58m. The distance from Myrtle Beach to Iowa is about 829 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Iowa?

  • Can I find deals for flights from Myrtle Beach to Iowa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Iowa.

  • Can I find deals for business class flights from Myrtle Beach to Iowa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Myrtle Beach to Iowa

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Myrtle Beach to Iowa

Discover the top airline that operate flights from Myrtle Beach to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$415FlexibilityNo cancel feeOn-time71%

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