Iowa

$310+ Cheap flights from Greenville (GSP) to Iowa

GSP — DSM
Dec 5 — Dec 121
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Cheap flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa

Wed 12/26:30 am -
1 stop4h 49m
Wed 12/95:00 am -
1 stop7h 26m
Deal found 11/3$310
Fri 11/275:40 am -
1 stop6h 04m
Tue 12/15:20 am -
1 stop6h 58m
Deal found 10/31$325
Fri 11/204:07 pm -
1 stop18h 54m
Sun 11/228:30 am -
1 stop5h 50m
Deal found 11/4$331
Wed 11/185:40 am -
2 stops11h 28m
Tue 12/15:05 am -
1 stop5h 08m
Deal found 11/3$359
Wed 11/1810:52 am -
1 stop4h 25m
Tue 12/15:00 am -
1 stop5h 07m
Deal found 11/3$363
Tue 11/1710:56 am -
2 stops13h 13m
Sat 11/215:15 am -
1 stop4h 52m
Deal found 11/2$374
Wed 11/1810:52 am -
1 stop4h 25m
Sun 11/2212:59 pm -
1 stop6h 53m
Deal found 11/3$378
Wed 11/1811:58 am -
2 stops11h 58m
Sun 11/226:00 am -
2 stops7h 16m
Deal found 11/3$379
Wed 11/1810:26 am -
2 stops12h 09m
Tue 12/18:00 am -
2 stops10h 13m
Deal found 11/3$388
Thu 11/198:44 am -
1 stop8h 27m
Mon 11/239:56 am -
2 stops21h 18m
Deal found 11/3$389
Mon 12/72:50 pm -
2 stops8h 15m
Fri 12/116:40 am -
2 stops15h 20m
Deal found 11/2$397
Fri 11/204:07 pm -
1 stop18h 54m
Mon 11/239:56 am -
2 stops21h 18m
Deal found 11/3$400

Find flight deals from Greenville to Iowa

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$310
(United Airlines)

Popular in

March

Cheapest in

September

Average price

$386
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
From Greenville to Iowa
Highest demand for flights based on searches. 18% potential increase in price ($102 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($32 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleCedar Rapids

GSP Greenville - CID Cedar Rapids

GSPCID

Greenville

Wed 12/2

6:30 am-10:19 am

1 stop4h 49m

Cedar Rapids

Wed 12/9

5:00 am-1:26 pm

1 stop7h 26m

$310

GreenvilleDes Moines

GSP Greenville - DSM Des Moines

GSPDSM

Greenville

Wed 2/3

12:11 pm-4:35 pm

1 stop5h 24m

Des Moines

Tue 2/9

5:30 am-11:06 am

1 stop4h 36m

$325
Quickest round-trip

GreenvilleDes Moines

GSP Greenville - DSM Des Moines

GSPDSM

Greenville

Fri 2/12

6:30 am-10:55 am

1 stop5h 25m

Des Moines

Mon 2/15

7:30 am-12:15 pm

1 stop3h 45m

$325

GreenvilleDes Moines

GSP Greenville - DSM Des Moines

GSPDSM

Greenville

Mon 12/7

5:34 pm-9:25 pm

1 stop4h 51m

Des Moines

Fri 12/11

2:56 pm-9:59 pm

1 stop6h 03m

$325

GreenvilleDes Moines

GSP Greenville - DSM Des Moines

GSPDSM

Greenville

Thu 2/4

5:38 am-11:01 am

1 stop6h 23m

Des Moines

Sun 2/7

10:40 am-5:58 pm

1 stop6h 18m

$359

GreenvilleCedar Rapids

GSP Greenville - CID Cedar Rapids

GSPCID

Greenville

Wed 11/18

10:52 am-2:17 pm

1 stop4h 25m

Cedar Rapids

Tue 12/1

5:00 am-11:07 am

1 stop5h 07m

$363

GreenvilleCedar Rapids

GSP Greenville - CID Cedar Rapids

GSPCID

Greenville

Tue 11/17

10:56 am-11:09 pm

2 stops13h 13m

Cedar Rapids

Sat 11/21

5:15 am-11:07 am

1 stop4h 52m

$374

GreenvilleCedar Rapids

GSP Greenville - CID Cedar Rapids

GSPCID

Greenville

Sat 2/6

6:30 am-10:23 am

1 stop4h 53m

Cedar Rapids

Tue 2/9

3:00 pm-9:03 pm

1 stop5h 03m

$391

GreenvilleDes Moines

GSP Greenville - DSM Des Moines

GSPDSM

Greenville

Mon 12/7

2:50 pm-10:05 pm

2 stops8h 15m

Des Moines

Fri 12/11

6:40 am-11:00 pm

2 stops15h 20m

$397

GreenvilleDes Moines

GSP Greenville - DSM Des Moines

GSPDSM

Greenville

Wed 12/2

6:30 am-10:37 am

1 stop5h 07m

Des Moines

Sat 12/5

1:15 pm-11:40 pm

2 stops9h 25m

$430

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 19 resultsSorted by cheapest first
1
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Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, September is the cheapest month in which you can book a flight from Greenville to Iowa (average of $357). Flying from Greenville to Iowa in March is currently the most expensive (average of $817). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 4h 49m. United Airlines provides one of the quickest options available for as low as $310. Airlines will cover a distance of 704 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Iowa?

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Greenville to Iowa (average of $357). Flying from Greenville to Iowa in March is currently the most expensive (average of $817). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Greenville to Iowa

Top 3 airlines flying from Greenville to Iowa

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$280Average$390FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$316Average$456FlexibilityNo cancel feeOn-time71%
DeltaCheapest$328Average$401FlexibilityNo cancel feeOn-timeN/A

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