Iowa

$156+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
May 7 — May 141
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Cheap flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.

This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:16 pm
GSP
-
MLI
1 stop4h 38m
American Airlines
Sun 4/265:15 am
MLI
-
GSP
1 stop4h 46m
American Airlines
Deal found 4/2$329
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:46 pm
GSP
-
OMA
1 stop18h 49m
Allegiant Air
Sun 7/199:48 am
OMA
-
GSP
1 stop20h 42m
Allegiant Air
Deal found 4/3$331
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:45 am
GSP
-
DSM
1 stop5h 23m
Delta
Tue 5/125:27 am
DSM
-
GSP
1 stop5h 38m
Delta
Deal found 4/3$336
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:33 am
GSP
-
MLI
2 stops8h 27m
United Airlines
Sat 5/96:35 am
MLI
-
GSP
2 stops6h 40m
United Airlines
Deal found 4/2$339
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:02 am
GSP
-
DSM
2 stops7h 52m
American Airlines
Tue 5/122:18 pm
DSM
-
GSP
1 stop4h 26m
American Airlines
Deal found 4/6$341
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:16 pm
GSP
-
CID
1 stop4h 34m
American Airlines
Sat 4/111:14 pm
CID
-
GSP
1 stop8h 26m
American Airlines
Deal found 4/3$347
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:32 pm
GSP
-
OMA
1 stop5h 50m
American Airlines
Wed 6/35:04 pm
OMA
-
GSP
1 stop5h 48m
American Airlines
Deal found 4/6$355
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:46 am
GSP
-
MLI
1 stop4h 08m
United Airlines
Sun 8/162:29 pm
MLI
-
GSP
1 stop5h 48m
United Airlines
Deal found 4/2$356
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:44 am
GSP
-
MLI
1 stop5h 38m
Delta
Sun 8/95:56 am
MLI
-
GSP
1 stop5h 17m
Delta
Deal found 4/2$364
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:12 pm
GSP
-
OMA
1 stop7h 20m
American Airlines
Tue 5/265:04 pm
OMA
-
GSP
1 stop5h 48m
American Airlines
Deal found 4/6$372
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:05 pm
GSP
-
DSM
1 stop7h 19m
Multiple Airlines
Sun 5/312:10 pm
DSM
-
GSP
2 stops25h 05m
Multiple Airlines
Deal found 4/6$374
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:32 pm
GSP
-
DSM
1 stop5h 45m
American Airlines
Mon 5/255:25 am
DSM
-
GSP
1 stop6h 42m
American Airlines
Deal found 4/6$375

Find flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated April 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(American Airlines)

One-way from

$156
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$415
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
From Greenville to Iowa
One-way flight from Greenville to Iowa
Highest demand for flights based on searches. 18% potential increase in price ($97 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Sat 5/2

10:40 am-3:12 pm

1 stop5h 32m

Moline Quad-City

Sat 5/9

6:35 am-2:10 pm

1 stop6h 35m

$329

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Thu 7/2

5:44 am-10:24 am

1 stop5h 40m

Moline Quad-City

Sat 7/4

5:17 pm-11:59 pm

1 stop5h 42m

$329

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Thu 7/16

3:46 pm-9:35 am

1 stop18h 49m

Omaha Eppley Airfield

Sun 7/19

9:48 am-7:30 am

1 stop20h 42m

$331

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 5/9

8:14 pm-11:49 pm

1 stop4h 35m

Des Moines

Tue 5/12

7:25 am-1:14 pm

1 stop4h 49m

$336

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Thu 8/13

10:46 am-1:54 pm

1 stop4h 08m

Moline Quad-City

Sun 8/16

2:29 pm-9:17 pm

1 stop5h 48m

$356

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Thu 8/6

5:44 am-10:22 am

1 stop5h 38m

Moline Quad-City

Sun 8/9

5:56 am-12:13 pm

1 stop5h 17m

$364

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Thu 6/4

6:30 am-1:56 pm

2 stops8h 26m

Moline Quad-City

Fri 6/12

2:31 pm-9:17 pm

1 stop5h 46m

$379

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Sat 5/2

5:45 pm-9:38 pm

1 stop4h 53m

Cedar Rapids

Tue 5/5

6:30 am-2:17 pm

2 stops6h 47m

$380

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Wed 4/29

11:35 am-7:28 pm

1 stop8h 53m

Des Moines

Fri 5/1

6:31 pm-11:56 pm

1 stop4h 25m

$381

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Wed 4/29

6:30 am-10:44 am

1 stop5h 14m

Des Moines

Fri 5/1

3:20 pm-10:58 pm

1 stop6h 38m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/6

Showing 1-10 of 42 resultsSorted by cheapest first
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Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $204). Flying from Greenville to Iowa in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Iowa?

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated April 7, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 5h 32m. United Airlines provides one of the quickest options available for as low as $329. Airlines will cover a distance of 637 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Iowa?

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $204). Flying from Greenville to Iowa in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$367FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$379FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$326Average$571FlexibilityNo cancel feeOn-time69%

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