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$159+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:49 am
GSP
-
CID
1 stop5h 25m
American Airlines
Wed 3/45:00 am
CID
-
GSP
1 stop4h 56m
American Airlines
Deal found 2/1$269
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:40 am
GSP
-
CID
2 stops6h 58m
Delta
Wed 3/45:33 am
CID
-
GSP
1 stop4h 40m
Delta
Deal found 2/1$274
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:49 am
GSP
-
CID
1 stop5h 25m
American Airlines
Sun 2/225:00 am
CID
-
GSP
1 stop4h 56m
American Airlines
Deal found 2/3$279
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:01 am
GSP
-
CID
1 stop7h 38m
American Airlines
Mon 2/163:45 pm
CID
-
GSP
1 stop5h 20m
American Airlines
Deal found 2/1$309
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:30 am
GSP
-
DSM
1 stop5h 23m
United Airlines
Sat 2/283:24 pm
DSM
-
GSP
1 stop4h 17m
United Airlines
Deal found 2/2$317
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:20 am
GSP
-
DSM
2 stops8h 45m
American Airlines
Sat 2/285:00 am
DSM
-
GSP
2 stops6h 00m
American Airlines
Deal found 2/2$327
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:35 pm
GSP
-
OMA
1 stop4h 35m
Southwest
Tue 5/194:20 pm
OMA
-
GSP
1 stop4h 20m
Southwest
Deal found 2/4$330
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:45 am
GSP
-
DSM
1 stop5h 18m
Delta
Tue 5/125:29 am
DSM
-
GSP
1 stop4h 16m
Delta
Deal found 2/3$330
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:36 am
GSP
-
DSM
1 stop5h 01m
United Airlines
Tue 5/121:05 pm
DSM
-
GSP
2 stops9h 00m
United Airlines
Deal found 2/3$335
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:29 am
GSP
-
OMA
1 stop5h 23m
American Airlines
Sun 3/11:58 pm
OMA
-
GSP
1 stop7h 16m
American Airlines
Deal found 2/1$338
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:50 am
GSP
-
DSM
1 stop6h 05m
Delta
Mon 4/272:44 pm
DSM
-
GSP
1 stop4h 17m
Delta
Deal found 2/2$341
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:20 am
GSP
-
DSM
2 stops9h 26m
American Airlines
Mon 4/2711:09 am
DSM
-
GSP
1 stop7h 35m
American Airlines
Deal found 2/2$346

Find flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$159
(Delta)

Popular in

April

Cheapest in

October

Average price

$366
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
Search Deals
From Greenville to Iowa
Search Deals
One-way flight from Greenville to Iowa
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Greenville

Fly to

Iowa

Route

Depart

Return

Price

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 2/25

6:01 am-12:39 pm

1 stop7h 38m

Cedar Rapids

Sat 2/28

4:48 pm-11:54 pm

1 stop6h 06m

$269

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 2/24

10:49 am-3:14 pm

1 stop5h 25m

Cedar Rapids

Wed 3/4

5:00 am-10:56 am

1 stop4h 56m

$269

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 2/25

6:30 am-10:44 am

1 stop5h 14m

Cedar Rapids

Sat 2/28

11:30 am-11:59 pm

2 stops11h 29m

$274

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 2/24

5:40 am-11:38 am

2 stops6h 58m

Cedar Rapids

Wed 3/4

5:33 am-11:13 am

1 stop4h 40m

$274

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 2/18

5:20 am-12:53 pm

2 stops8h 33m

Cedar Rapids

Sun 2/22

5:00 am-10:56 am

1 stop4h 56m

$284

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Wed 2/25

6:30 am-10:53 am

1 stop5h 23m

Des Moines

Sat 2/28

3:24 pm-8:41 pm

1 stop4h 17m

$317

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Wed 2/25

5:20 am-1:05 pm

2 stops8h 45m

Des Moines

Sat 2/28

5:00 am-12:00 pm

2 stops6h 00m

$327

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Thu 5/14

1:00 pm-5:53 pm

1 stop5h 53m

Des Moines

Tue 5/19

5:29 am-12:03 pm

1 stop5h 34m

$330

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 5/9

6:45 am-11:03 am

1 stop5h 18m

Des Moines

Tue 5/12

5:29 am-10:45 am

1 stop4h 16m

$330

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 5/9

6:36 am-12:30 pm

1 stop6h 54m

Des Moines

Tue 5/12

3:20 pm-8:49 pm

1 stop4h 29m

$330

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 47 results
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Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in January is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated February 4, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,144 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,144 reviews
Delta
7.9
Good
8,144 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,236 reviews
Delta
7.9
Good
8,144 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,222 reviews
Delta
7.9
Good
8,144 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 5h 14m. American Airlines provides one of the quickest options available for as low as $274. Airlines will cover a distance of 704 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Iowa?

    The most popular route from Greenville to Iowa is Greenville - Des Moines. You may also consider Greenville - Moline Quad-City or Greenville - Omaha Eppley Airfield.

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in January is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$359FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$326Average$571FlexibilityNo cancel feeOn-time69%

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