HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$241+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:38 amGSP - CID
1 stop4h 55mAmerican Airlines
Tue 12/165:00 amCID - GSP
1 stop5h 31mAmerican Airlines
Deal found 10/28$249
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:35 amGSP - CID
2 stops11h 10mDelta
Tue 12/165:50 amCID - GSP
2 stops10h 59mDelta
Deal found 10/28$259
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:03 pmGSP - DSM
1 stop14h 45mMultiple Airlines
Thu 12/112:56 pmDSM - GSP
1 stop22h 14mMultiple Airlines
Deal found 10/29$277
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:00 pmGSP - DSM
1 stop24h 42mAllegiant Air
Thu 12/112:56 pmDSM - GSP
1 stop22h 14mAllegiant Air
Deal found 10/29$291
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/203:56 pmGSP - DSM
1 stop25h 44mMultiple Airlines
Mon 11/241:56 pmDSM - GSP
1 stop17h 57mMultiple Airlines
Deal found 10/30$295
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:00 pmGSP - DSM
2 stops23h 58mMultiple Airlines
Thu 12/112:56 pmDSM - GSP
1 stop22h 14mMultiple Airlines
Deal found 10/29$297
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:03 amGSP - DSM
1 stop5h 39mAmerican Airlines
Thu 12/44:07 pmDSM - GSP
1 stop6h 50mAmerican Airlines
Deal found 10/28$322
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:14 pmGSP - OMA
1 stop4h 45mAmerican Airlines
Thu 11/276:11 amOMA - GSP
1 stop5h 09mAmerican Airlines
Deal found 10/29$330
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:35 amGSP - DSM
2 stops12h 00mSouthwest
Thu 12/116:15 amDSM - GSP
2 stops12h 25mSouthwest
Deal found 10/29$340
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:27 amGSP - CID
1 stop5h 41mAmerican Airlines
Sun 11/25:35 amCID - GSP
1 stop6h 31mAmerican Airlines
Deal found 10/28$349
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:55 amGSP - DSM
2 stops7h 27mAmerican Airlines
Mon 11/243:18 pmDSM - GSP
1 stop6h 53mAmerican Airlines
Deal found 10/29$349
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:35 amGSP - DSM
2 stops12h 00mSouthwest
Thu 12/116:15 amDSM - GSP
2 stops12h 25mSouthwest
Deal found 10/29$377

Cheap flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(Delta)

One-way from

$241
(Southwest)

Popular in

April

Cheapest in

March

Average price

$337
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
Search Deals
From Greenville to Iowa
Search Deals
One-way flight from Greenville to Iowa
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Greenville

Fly to

Iowa

Route

Depart

Return

Price

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Tue 4/14

5:05 pm-10:31 pm

1 stop6h 26m

Moline Quad-City

Sat 4/18

5:00 pm-11:40 pm

1 stop5h 40m

$274

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Sat 1/17

8:40 am-3:34 pm

1 stop7h 54m

Omaha Eppley Airfield

Mon 1/19

6:06 pm-11:55 pm

1 stop4h 49m

$287

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Sat 1/17

6:20 am-5:36 pm

2 stops12h 16m

Omaha Eppley Airfield

Mon 1/19

3:21 pm-8:47 pm

1 stop4h 26m

$292

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 12/5

8:03 pm-9:48 am

1 stop14h 45m

Des Moines

Thu 12/11

2:56 pm-8:49 pm

2 stops28h 53m

$303

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 4/15

5:05 pm-9:50 pm

1 stop5h 45m

Cedar Rapids

Sat 4/18

12:05 pm-10:00 pm

2 stops8h 55m

$309

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Sat 1/17

10:32 am-5:48 pm

2 stops8h 16m

Omaha Eppley Airfield

Mon 1/19

12:03 pm-11:26 pm

2 stops10h 23m

$318

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 4/15

7:25 am-12:00 pm

1 stop5h 35m

Cedar Rapids

Sat 4/18

2:55 pm-9:28 pm

1 stop5h 33m

$319

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Tue 4/14

10:21 am-8:58 pm

2 stops11h 37m

Moline Quad-City

Sat 4/18

3:52 pm-9:11 pm

1 stop4h 19m

$324

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Wed 11/26

8:14 pm-11:59 pm

1 stop4h 45m

Omaha Eppley Airfield

Thu 11/27

6:11 am-12:20 pm

1 stop5h 09m

$330

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Thu 12/4

10:35 am-9:35 pm

2 stops12h 00m

Des Moines

Thu 12/11

6:15 am-7:40 pm

2 stops12h 25m

$340

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, November is the cheapest month in which you can book a flight from Greenville to Iowa (average of $157). Flying from Greenville to Iowa in December is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to IA?

Find hourly flight availability from Greenville to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from Greenville to Iowa in the evening. Doing so could potentially save you 22% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 6h 26m. Delta provides one of the quickest options available for as low as $274. Airlines will cover a distance of 637 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Iowa one-way?

    For one-way options, check prices for Southwest. According to our data, you can fly for as low as $241. Users have also found prices from $260 and $300 on Delta and United Airlines, respectively.

  • What are the most popular routes from Greenville to Iowa?

    The most popular route from Greenville to Iowa is Greenville - Cedar Rapids. You may also consider Greenville - Des Moines or Greenville - Omaha Eppley Airfield.

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, November is the cheapest month in which you can book a flight from Greenville to Iowa (average of $157). Flying from Greenville to Iowa in December is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to LaGuardia flights
Charlotte to Newark flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Denver flights
Charlotte to Las Vegas flights
Charlotte to O'Hare Intl flights
Charlotte to Hobby flights
Charlotte to Orlando flights
Charlotte to Boston flights
Charleston to John F Kennedy Intl flights
Charlotte to George Bush Intcntl flights
Charlotte to Miami flights
Charlotte to Fort Lauderdale flights
Charleston to Newark flights
Charlotte to Sky Harbor Intl flights
Charlotte to Los Angeles flights
Savannah to John F Kennedy Intl flights
Charlotte to Love Field flights
Greenville to LaGuardia flights
Greenville to Newark flights
Charlotte to Baltimore flights
Charlotte to Seattle flights
Charlotte to Salt Lake City flights
Charlotte to Philadelphia flights
Greenville to John F Kennedy Intl flights
Charleston to Fort Lauderdale flights
Charleston to LaGuardia flights
Charlotte to Nashville flights
Savannah to Newark flights
Charlotte to New Orleans flights
Charlotte to Minneapolis flights
Charlotte to Dulles Intl flights
Charlotte to Midway flights
Charlotte to Atlanta flights
Charleston to O'Hare Intl flights
Charlotte to San Francisco flights
Savannah to LaGuardia flights
Charlotte to Reagan-National flights
Columbia to LaGuardia flights
Charleston to Miami flights
Charlotte to Ontario flights
Greenville to St Petersburg flights
Charlotte to Honolulu flights
Columbia to John F Kennedy Intl flights
Myrtle Beach to Newark flights
Greenville to Sarasota flights
Charlotte to San Diego flights
Charlotte to Austin flights
Savannah to Dulles Intl flights

Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$266Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$480FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.