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$159+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amGSP - OMA
1 stop7h 08mAmerican Airlines
Fri 1/166:19 pmOMA - GSP
1 stop4h 40mAmerican Airlines
Deal found 12/30$492
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:40 amGSP - OMA
2 stops10h 10mSouthwest
Fri 1/1610:40 amOMA - GSP
2 stops8h 40mSouthwest
Deal found 12/29$553
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:50 pmGSP - OMA
2 stops9h 40mUnited Airlines
Fri 1/163:21 pmOMA - GSP
1 stop4h 26mUnited Airlines
Deal found 12/30$567
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:23 amGSP - DSM
2 stops11h 02mUnited Airlines
Tue 1/63:35 pmDSM - GSP
1 stop4h 12mUnited Airlines
Deal found 12/30$600
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:23 amGSP - DSM
2 stops11h 02mUnited Airlines
Sat 1/33:14 pmDSM - GSP
1 stop4h 33mUnited Airlines
Deal found 12/30$650
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:23 amGSP - DSM
2 stops11h 02mUnited Airlines
Fri 1/26:00 amDSM - GSP
2 stops10h 01mUnited Airlines
Deal found 12/30$655
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:15 pmGSP - DSM
1 stop8h 43mUnited Airlines
Thu 1/88:10 amDSM - GSP
1 stop6h 25mUnited Airlines
Deal found 12/30$693
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:23 amGSP - DSM
2 stops11h 02mUnited Airlines
Sun 1/411:30 amDSM - GSP
1 stop8h 17mUnited Airlines
Deal found 12/30$742
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:02 amGSP - OMA
1 stop5h 06mAmerican Airlines
Sun 1/42:12 pmOMA - GSP
1 stop6h 58mAmerican Airlines
Deal found 12/29$762
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:23 amGSP - DSM
2 stops15h 07mUnited Airlines
Mon 1/56:46 pmDSM - GSP
2 stops18h 33mUnited Airlines
Deal found 12/30$764
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:43 pmGSP - DSM
1 stop9h 02mDelta
Mon 1/51:03 pmDSM - GSP
1 stop4h 52mDelta
Deal found 12/30$867
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:04 pmGSP - OMA
2 stops9h 54mUnited Airlines
Sun 1/49:05 amOMA - GSP
2 stops10h 42mUnited Airlines
Deal found 12/29$953

Find flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated December 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$304
(Delta)

One-way from

$159
(American Airlines)

Popular in

April

Cheapest in

October

Average price

$629
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
Search Deals
From Greenville to Iowa
Search Deals
One-way flight from Greenville to Iowa
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Greenville

Fly to

Iowa

Route

Depart

Return

Price

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Thu 5/7

3:42 pm-9:50 pm

1 stop7h 08m

Cedar Rapids

Sun 5/10

5:45 am-1:10 pm

1 stop6h 25m

$304

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Sat 1/17

6:35 am-10:30 am

1 stop4h 55m

Omaha Eppley Airfield

Sun 1/18

11:26 am-4:52 pm

1 stop4h 26m

$339

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 2/14

6:30 am-10:53 am

1 stop5h 23m

Des Moines

Wed 2/18

3:24 pm-8:41 pm

1 stop4h 17m

$339

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Sat 2/14

10:40 am-4:47 pm

1 stop7h 07m

Moline Quad-City

Wed 2/18

10:46 am-11:59 pm

2 stops12h 13m

$344

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Sat 2/14

6:30 am-10:44 am

1 stop5h 14m

Cedar Rapids

Wed 2/18

1:10 pm-11:59 pm

2 stops9h 49m

$344

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Sat 2/14

6:30 am-10:29 am

1 stop4h 59m

Omaha Eppley Airfield

Sat 2/21

3:22 pm-8:41 pm

1 stop4h 19m

$363

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Wed 1/14

10:23 am-4:14 pm

1 stop6h 51m

Omaha Eppley Airfield

Sun 1/18

3:07 pm-8:48 pm

1 stop4h 41m

$368

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Wed 3/11

7:05 am-1:18 pm

1 stop7h 13m

Des Moines

Fri 3/13

5:00 am-10:56 am

1 stop4h 56m

$372

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 3/10

8:17 pm-11:40 pm

1 stop4h 23m

Des Moines

Fri 3/13

5:00 am-10:56 am

1 stop4h 56m

$372

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 2/13

11:29 am-11:40 pm

1 stop13h 11m

Des Moines

Mon 2/16

7:44 pm-10:59 am

1 stop14h 15m

$380

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 22 results
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Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated December 31, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,124 reviews
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,074 reviews
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 4h 55m. Delta provides one of the quickest options available for as low as $339. Airlines will cover a distance of 863 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Iowa?

    The most popular route from Greenville to Iowa is Greenville - Omaha Eppley Airfield. You may also consider Greenville - Des Moines or Greenville - Cedar Rapids.

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$376FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$326Average$571FlexibilityNo cancel feeOn-time69%

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