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$159+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:40 pm
GSP
-
CID
1 stop6h 23m
Delta
Tue 5/55:45 am
CID
-
GSP
1 stop5h 35m
Delta
Deal found 1/21$269
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:40 pm
GSP
-
CID
1 stop6h 23m
Delta
Sat 5/912:05 pm
CID
-
GSP
2 stops8h 55m
Delta
Deal found 1/21$274
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:25 am
GSP
-
CID
1 stop7h 18m
American Airlines
Mon 2/94:16 pm
CID
-
GSP
1 stop6h 43m
American Airlines
Deal found 1/21$279
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2512:05 pm
GSP
-
CID
2 stops10h 21m
United Airlines
Sat 2/2811:30 am
CID
-
GSP
2 stops11h 29m
United Airlines
Deal found 1/20$280
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:12 pm
GSP
-
CID
1 stop5h 35m
Delta
Mon 2/94:17 pm
CID
-
GSP
2 stops6h 33m
Delta
Deal found 1/21$284
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:30 am
GSP
-
CID
1 stop5h 14m
United Airlines
Wed 3/411:30 am
CID
-
GSP
2 stops11h 29m
United Airlines
Deal found 1/20$294
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:30 am
GSP
-
DSM
1 stop5h 23m
United Airlines
Tue 2/173:24 pm
DSM
-
GSP
1 stop4h 17m
United Airlines
Deal found 1/20$317
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:40 am
GSP
-
DSM
1 stop5h 36m
Delta
Tue 4/215:45 am
DSM
-
GSP
1 stop5h 35m
Delta
Deal found 1/21$319
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:20 am
GSP
-
DSM
1 stop5h 36m
American Airlines
Tue 2/175:00 am
DSM
-
GSP
2 stops7h 15m
American Airlines
Deal found 1/20$322
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1411:07 am
GSP
-
OMA
1 stop6h 29m
American Airlines
Mon 2/165:17 pm
OMA
-
GSP
1 stop5h 37m
American Airlines
Deal found 1/20$329
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1012:06 pm
GSP
-
OMA
1 stop5h 08m
American Airlines
Tue 2/1712:16 pm
OMA
-
GSP
1 stop10h 23m
American Airlines
Deal found 1/21$330
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:40 am
GSP
-
DSM
1 stop5h 36m
Delta
Sat 4/1812:00 pm
DSM
-
GSP
1 stop4h 28m
Delta
Deal found 1/21$330

Find flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$159
(Delta)

Popular in

April

Cheapest in

October

Average price

$384
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
Search Deals
From Greenville to Iowa
Search Deals
One-way flight from Greenville to Iowa
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Greenville

Fly to

Iowa

Route

Depart

Return

Price

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Fri 2/27

7:29 am-12:53 pm

1 stop6h 24m

Cedar Rapids

Sun 3/1

1:24 pm-10:40 pm

1 stop8h 16m

$269

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 4/29

5:40 pm-11:03 pm

1 stop6h 23m

Cedar Rapids

Tue 5/5

5:45 am-5:28 pm

2 stops10h 43m

$274

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 2/25

6:30 am-12:15 pm

1 stop6h 45m

Cedar Rapids

Sat 2/28

11:30 am-11:59 pm

2 stops11h 29m

$274

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Thu 2/5

6:25 am-12:43 pm

1 stop7h 18m

Cedar Rapids

Mon 2/9

4:16 pm-11:59 pm

1 stop6h 43m

$279

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 4/29

6:00 am-12:47 pm

2 stops7h 47m

Cedar Rapids

Sat 5/9

6:30 am-2:17 pm

2 stops6h 47m

$280

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Thu 2/5

5:40 am-11:31 am

2 stops6h 51m

Cedar Rapids

Mon 2/9

4:17 pm-11:50 pm

2 stops6h 33m

$290

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 2/24

6:30 am-10:44 am

1 stop5h 14m

Cedar Rapids

Wed 3/4

11:30 am-11:59 pm

2 stops11h 29m

$294

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 2/14

6:30 am-10:53 am

1 stop5h 23m

Des Moines

Tue 2/17

3:24 pm-8:41 pm

1 stop4h 17m

$317

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 4/14

5:40 am-10:16 am

1 stop5h 36m

Des Moines

Wed 4/22

7:28 am-3:14 pm

1 stop6h 46m

$319

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 2/14

11:07 am-6:19 pm

2 stops8h 12m

Des Moines

Tue 2/17

5:00 am-1:15 pm

2 stops7h 15m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 37 results
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Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in February is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated January 21, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,088 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,088 reviews
Delta
7.9
Good
8,088 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,191 reviews
Delta
7.9
Good
8,088 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,088 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 6h 23m. American Airlines provides one of the quickest options available for as low as $274. Airlines will cover a distance of 704 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Iowa?

    The most popular route from Greenville to Iowa is Greenville - Des Moines. You may also consider Greenville - Omaha Eppley Airfield or Greenville - Cedar Rapids.

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in February is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$359FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$326Average$571FlexibilityNo cancel feeOn-time69%

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