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$279+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:38 amGSP - CID
1 stop7h 50mAmerican Airlines
Sat 12/65:53 pmCID - GSP
1 stop5h 25mAmerican Airlines
Deal found 11/16$279
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:45 amGSP - DSM
1 stop4h 53mDelta
Wed 12/103:17 pmDSM - GSP
1 stop5h 47mDelta
Deal found 11/16$317
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:05 pmGSP - CID
2 stops10h 14mUnited Airlines
Sat 12/68:00 amCID - GSP
2 stops10h 10mUnited Airlines
Deal found 11/16$319
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:05 pmGSP - DSM
2 stops10h 32mUnited Airlines
Wed 12/103:17 pmDSM - GSP
1 stop4h 32mUnited Airlines
Deal found 11/16$322
This American Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 amGSP - OMA
1 stop7h 08mAmerican Airlines
Sun 1/43:44 pmOMA - GSP
1 stop7h 08mAmerican Airlines
Deal found 11/14$350
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amGSP - DSM
1 stop5h 47mAmerican Airlines
Sat 1/33:28 pmDSM - GSP
1 stop7h 24mAmerican Airlines
Deal found 11/15$350
This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:16 pmGSP - CID
1 stop6h 22mDelta
Sun 11/165:54 amCID - GSP
1 stop6h 16mDelta
Deal found 11/15$369
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:03 amGSP - OMA
1 stop5h 05mAmerican Airlines
Mon 12/12:07 pmOMA - GSP
1 stop6h 57mAmerican Airlines
Deal found 11/16$390
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:26 pmGSP - OMA
1 stop25h 21mMultiple Airlines
Mon 12/298:26 pmOMA - GSP
2 stops42h 29mMultiple Airlines
Deal found 11/14$406
This Southwest deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:40 amGSP - OMA
2 stops10h 10mSouthwest
Sun 1/49:05 pmOMA - GSP
2 stops11h 40mSouthwest
Deal found 11/14$420
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:59 pmGSP - OMA
1 stop5h 09mDelta
Wed 12/3112:10 pmOMA - GSP
1 stop4h 25mDelta
Deal found 11/14$442
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:14 pmGSP - OMA
1 stop4h 45mAmerican Airlines
Fri 12/52:03 pmOMA - GSP
1 stop6h 58mAmerican Airlines
Deal found 11/16$467

Cheap flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(American Airlines)

Popular in

April

Cheapest in

October

Average price

$314
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
Search Deals
From Greenville to Iowa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Greenville

Fly to

Iowa

Route

Depart

Return

Price

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 12/2

7:38 am-2:28 pm

1 stop7h 50m

Cedar Rapids

Sat 12/6

5:53 pm-12:18 am

1 stop5h 25m

$279

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 1/13

7:20 am-11:24 am

1 stop5h 04m

Des Moines

Sat 1/17

10:16 am-6:14 pm

1 stop6h 58m

$315

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Tue 2/24

5:40 am-10:05 am

1 stop5h 25m

Omaha Eppley Airfield

Wed 2/25

11:00 am-6:39 pm

1 stop6h 39m

$317

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 12/2

6:45 am-10:38 am

1 stop4h 53m

Des Moines

Wed 12/10

3:17 pm-10:04 pm

1 stop5h 47m

$317

GreenvilleMoline

GSP - MLI

GSPMLI

Greenville

Tue 4/14

5:05 pm-10:31 pm

1 stop6h 26m

Moline Quad-City

Sat 4/18

5:00 pm-11:40 pm

1 stop5h 40m

$318

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 12/2

12:05 pm-9:19 pm

2 stops10h 14m

Cedar Rapids

Sat 12/6

8:00 am-7:10 pm

2 stops10h 10m

$319

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 1/13

6:20 am-2:33 pm

2 stops9h 13m

Des Moines

Sat 1/17

8:10 am-3:35 pm

1 stop6h 25m

$320

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 1/13

12:37 pm-8:02 pm

1 stop8h 25m

Des Moines

Sat 1/17

1:16 pm-11:51 pm

2 stops9h 35m

$320

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 12/2

12:05 pm-9:37 pm

2 stops10h 32m

Des Moines

Wed 12/10

3:17 pm-8:49 pm

1 stop4h 32m

$322

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Tue 1/13

11:15 am-7:20 pm

2 stops9h 05m

Des Moines

Sat 1/17

6:45 am-3:35 pm

2 stops7h 50m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 27 results
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Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in December is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to IA?

Find hourly flight availability from Greenville to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

It’s typically best to fly out from Greenville to Iowa in the evening. Doing so could potentially save you 22% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Greenville to Iowa?

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 5h 04m. American Airlines provides one of the quickest options available for as low as $315. Airlines will cover a distance of 771 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Iowa one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $300. Users have also found prices from $336 and $440 on Southwest and Allegiant Air, respectively.

  • What are the most popular routes from Greenville to Iowa?

    The most popular route from Greenville to Iowa is Greenville - Des Moines. You may also consider Greenville - Omaha Eppley Airfield or Greenville - Cedar Rapids.

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $208). Flying from Greenville to Iowa in December is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Iowa

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Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$312FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$266Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$452FlexibilityNo cancel feeOn-time69%

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