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$132+ Cheap flights from Greenville (GSP) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — DSM
Apr 23 — Apr 301
Thu 4/23
Thu 4/30
1 adult, Economy
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Cheap flight deals from Greenville to Iowa

Cheapest flights from Greenville to Iowa
Explore the most affordable flight options available from Greenville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:35 am
GSP
-
DSM
1 stop8h 53m
Delta
Tue 4/217:28 am
DSM
-
GSP
1 stop6h 46m
Delta
Deal found 3/23$263
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
GSP
-
DSM
2 stops8h 46m
American Airlines
Tue 4/212:16 pm
DSM
-
GSP
1 stop4h 30m
American Airlines
Deal found 3/23$268
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:05 pm
GSP
-
DSM
2 stops6h 05m
Southwest
Tue 4/215:30 am
DSM
-
GSP
2 stops9h 50m
Southwest
Deal found 3/23$273
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:35 am
GSP
-
DSM
1 stop8h 53m
Delta
Tue 4/212:44 pm
DSM
-
GSP
1 stop6h 29m
Delta
Deal found 3/23$290
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:51 pm
GSP
-
DSM
1 stop18h 22m
Multiple Airlines
Sat 5/911:00 am
DSM
-
GSP
1 stop20h 43m
Multiple Airlines
Deal found 3/22$296
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:31 am
GSP
-
DSM
1 stop5h 39m
American Airlines
Tue 5/122:16 pm
DSM
-
GSP
1 stop7h 46m
American Airlines
Deal found 3/23$300
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:48 pm
GSP
-
OMA
1 stop19h 13m
Allegiant Air
Sun 4/59:32 am
OMA
-
GSP
1 stop6h 39m
Allegiant Air
Deal found 3/22$314
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:50 am
GSP
-
DSM
1 stop6h 05m
Delta
Tue 4/212:44 pm
DSM
-
GSP
1 stop4h 00m
Delta
Deal found 3/23$317
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:50 pm
GSP
-
DSM
2 stops10h 15m
Southwest
Sat 5/96:40 am
DSM
-
GSP
2 stops8h 55m
Southwest
Deal found 3/22$328
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:32 pm
GSP
-
OMA
1 stop5h 50m
American Airlines
Tue 6/235:04 pm
OMA
-
GSP
1 stop5h 48m
American Airlines
Deal found 3/24$335
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 am
GSP
-
CID
1 stop5h 05m
United Airlines
Wed 4/82:34 pm
CID
-
GSP
1 stop5h 13m
United Airlines
Deal found 3/20$339
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:41 pm
GSP
-
OMA
1 stop6h 39m
United Airlines
Tue 6/236:00 am
OMA
-
GSP
2 stops7h 20m
United Airlines
Deal found 3/24$340

Find flight deals from Greenville to Iowa

Keep the following information in mind while searching for Greenville to Iowa flight deals. Data was last updated March 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$263
(Delta)

One-way from

$132
(American Airlines)

Popular in

March

Cheapest in

October

Average price

$786
Provider with most accurate pricing for Greenville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Des Moines flights.
Search Deals
From Greenville to Iowa
Search Deals
One-way flight from Greenville to Iowa
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($121 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Greenville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 5/9

5:40 am-11:08 am

1 stop6h 28m

Des Moines

Tue 5/12

2:33 pm-8:13 pm

1 stop4h 40m

$337

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Sat 4/4

6:30 am-10:35 am

1 stop5h 05m

Cedar Rapids

Wed 4/8

2:34 pm-8:47 pm

1 stop5h 13m

$339

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 4/7

6:30 am-12:47 pm

1 stop7h 17m

Cedar Rapids

Sat 4/11

1:28 pm-8:47 pm

1 stop6h 19m

$339

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Tue 4/21

6:30 am-10:32 am

1 stop5h 02m

Omaha Eppley Airfield

Wed 4/22

6:00 am-11:54 am

1 stop4h 54m

$343

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Tue 4/7

8:16 pm-11:50 pm

1 stop4h 34m

Cedar Rapids

Sat 4/11

6:00 am-2:11 pm

2 stops7h 11m

$344

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Sat 5/9

7:02 am-1:46 pm

2 stops7h 44m

Des Moines

Tue 5/12

6:00 am-3:03 pm

2 stops8h 03m

$347

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Thu 5/28

6:25 pm-11:15 pm

2 stops5h 50m

Omaha Eppley Airfield

Sun 5/31

1:00 pm-11:25 pm

2 stops9h 25m

$373

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 5/1

6:36 am-10:37 am

1 stop5h 01m

Des Moines

Mon 5/4

5:00 am-2:17 pm

2 stops8h 17m

$396

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 5/8

6:45 am-11:08 am

1 stop5h 23m

Des Moines

Sun 5/10

2:33 pm-8:13 pm

1 stop4h 40m

$407

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 7/10

6:45 am-10:14 am

1 stop4h 29m

Des Moines

Tue 7/21

2:15 pm-8:17 pm

1 stop5h 02m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 47 resultsSorted by cheapest first
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5

Best time to book a flight from Greenville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Iowa

What is the cheapest month to book a flight from Greenville to Iowa?

Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $207). Flying from Greenville to Iowa in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 24, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Greenville to Iowa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,320 reviews
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,467 reviews
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,492 reviews
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Iowa?

    If you book a flight to Iowa from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Iowa?

    A quick flight from Greenville to Iowa can take about 4h 34m. Delta provides one of the quickest options available for as low as $344. Airlines will cover a distance of 704 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Iowa?

    The most popular route from Greenville to Iowa is Greenville - Des Moines. You may also consider Greenville - Omaha Eppley Airfield or Greenville - Cedar Rapids.

  • Can I find deals for flights from Greenville to Iowa that include hotel bookings?

    Yes. In addition to deals on Greenville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Iowa.

  • Can I find deals for business class flights from Greenville to Iowa?

    Yes. Cheapflights offers flight deals from Greenville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Iowa (average of $207). Flying from Greenville to Iowa in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to Iowa

Discover the top 3 airlines that operate flights from Greenville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$367FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$326Average$571FlexibilityNo cancel feeOn-time69%

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