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$222+ Cheap flights from Buffalo (BUF) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — DSM
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Buffalo to Iowa

Cheapest flights from Buffalo to Iowa
Explore the most affordable flight options available from Buffalo to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:10 amBUF - OMA
1 stop6h 12mDelta
Mon 12/295:39 pmOMA - BUF
1 stop4h 49mDelta
Deal found 12/9$368
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amBUF - ALO
2 stops9h 39mAmerican Airlines
Mon 12/293:09 pmALO - BUF
1 stop6h 35mAmerican Airlines
Deal found 12/10$390
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:00 amBUF - MLI
1 stop5h 50mUnited Airlines
Mon 12/156:30 amMLI - BUF
1 stop5h 42mUnited Airlines
Deal found 12/10$439
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:50 pmBUF - CID
1 stop6h 12mUnited Airlines
Mon 12/156:35 amCID - BUF
1 stop5h 37mUnited Airlines
Deal found 12/10$439
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:10 amBUF - OMA
1 stop6h 12mDelta
Tue 12/305:39 pmOMA - BUF
1 stop4h 49mDelta
Deal found 12/10$453
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amBUF - OMA
2 stops9h 45mAmerican Airlines
Mon 12/293:44 pmOMA - BUF
1 stop5h 45mAmerican Airlines
Deal found 12/9$460
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:41 pmBUF - OMA
1 stop5h 17mUnited Airlines
Mon 12/293:14 pmOMA - BUF
1 stop4h 40mUnited Airlines
Deal found 12/10$474
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:30 amBUF - CID
1 stop5h 04mUnited Airlines
Mon 12/293:00 pmCID - BUF
1 stop4h 54mUnited Airlines
Deal found 12/10$480
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:29 amBUF - OMA
2 stops10h 50mUnited Airlines
Tue 12/308:00 amOMA - BUF
1 stop4h 24mUnited Airlines
Deal found 12/11$513
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:10 amBUF - OMA
1 stop4h 37mDelta
Fri 1/25:39 pmOMA - BUF
1 stop4h 49mDelta
Deal found 12/10$587
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:37 pmBUF - OMA
2 stops10h 22mAmerican Airlines
Fri 1/25:38 pmOMA - BUF
1 stop5h 21mAmerican Airlines
Deal found 12/10$592
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:30 amBUF - CID
1 stop5h 04mUnited Airlines
Fri 12/195:28 pmCID - BUF
2 stops15h 18mUnited Airlines
Deal found 12/10$643

Find flight deals from Buffalo to Iowa

Keep the following information in mind while searching for Buffalo to Iowa flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$244
(United Airlines)

One-way from

$222
(Kiwi.com)

Popular in

January

Cheapest in

June

Average price

$382
Provider with most accurate pricing for Buffalo-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Des Moines flights.
Search Deals
From Buffalo to Iowa
Search Deals
One-way flight from Buffalo to Iowa
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($64 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Buffalo to Iowa that are best for you.

Fly from

Buffalo

Fly to

Iowa

Route

Depart

Return

Price

BuffaloMoline

BUF - MLI

BUFMLI

Buffalo

Sat 1/10

11:24 am-9:36 pm

2 stops11h 12m

Moline Quad-City

Sat 1/17

3:45 pm-8:29 pm

1 stop3h 44m

$244

BuffaloCedar Rapids

BUF - CID

BUFCID

Buffalo

Fri 1/9

5:16 pm-10:15 pm

1 stop5h 59m

Cedar Rapids

Fri 1/16

6:25 am-12:08 pm

1 stop4h 43m

$289

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Tue 1/20

5:44 pm-8:54 pm

1 stop4h 10m

Des Moines

Sat 1/24

12:25 pm-4:59 pm

1 stop3h 34m

$293

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Tue 1/20

2:49 pm-9:50 pm

2 stops8h 01m

Des Moines

Sat 1/24

7:50 am-1:24 pm

1 stop4h 34m

$298

BuffaloMoline

BUF - MLI

BUFMLI

Buffalo

Sat 1/10

6:42 am-10:58 am

1 stop5h 16m

Moline Quad-City

Sat 1/17

6:15 am-12:08 pm

1 stop4h 53m

$304

BuffaloCedar Rapids

BUF - CID

BUFCID

Buffalo

Sat 1/31

1:59 pm-7:08 pm

1 stop6h 09m

Cedar Rapids

Wed 2/4

8:30 am-1:24 pm

1 stop3h 54m

$319

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Thu 1/8

2:56 pm-7:34 pm

1 stop5h 38m

Des Moines

Sun 1/11

5:16 pm-11:56 pm

1 stop5h 40m

$363

BuffaloOmaha

BUF - OMA

BUFOMA

Buffalo

Thu 12/25

6:10 am-11:22 am

1 stop6h 12m

Omaha Eppley Airfield

Mon 12/29

5:39 pm-11:28 pm

1 stop4h 49m

$368

BuffaloMoline

BUF - MLI

BUFMLI

Buffalo

Sat 1/31

6:00 am-3:09 pm

2 stops10h 09m

Moline Quad-City

Wed 2/4

3:45 pm-8:29 pm

1 stop3h 44m

$384

BuffaloOmaha

BUF - OMA

BUFOMA

Buffalo

Thu 4/2

4:57 pm-12:06 am

1 stop8h 09m

Omaha Eppley Airfield

Tue 4/7

7:10 am-2:19 pm

1 stop6h 09m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 22 results
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Best time to book a flight from Buffalo to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Iowa

What is the cheapest month to book a flight from Buffalo to Iowa?

Currently, June is the cheapest month in which you can book a flight from Buffalo to Iowa (average of $119). Flying from Buffalo to Iowa in August is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to IA?

Find hourly flight availability from Buffalo to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Buffalo to Iowa in the evening. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Buffalo to Iowa have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Iowa?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to Iowa. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How long is the flight from Buffalo to Iowa?

    United Airlines, American Airlines, and Delta can get you from Buffalo to Iowa in just under 4h 10m. Your travel time can differ by up to 7h 02m. Buffalo and Iowa are separated by a distance of 768 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Buffalo to Iowa?

    While some choose either Buffalo - Omaha Eppley Airfield or Buffalo - Cedar Rapids, Buffalo - Des Moines is the most popular route from Buffalo to Iowa.

  • Can I find deals for flights from Buffalo to Iowa that include hotel bookings?

    Yes. In addition to deals on Buffalo to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Iowa.

  • Can I find deals for business class flights from Buffalo to Iowa?

    Yes. Cheapflights offers flight deals from Buffalo to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Iowa?

    Currently, June is the cheapest month in which you can book a flight from Buffalo to Iowa (average of $119). Flying from Buffalo to Iowa in August is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Buffalo to Iowa

Discover the top 3 airlines that operate flights from Buffalo to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$279Average$497FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$294Average$395FlexibilityNo cancel feeOn-time69%

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