$131+ Cheap flights from Iowa to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BUF
Mai 23 — Mai 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Iowa to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Iowa to BuffaloExplore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/195:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Di 5/266:25 am
BUF
- OMA
1 stop4h 20m
Delta
Deal found 4/21![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/136:30 am
OMA
- BUF
1 stop6h 37m
Delta
Di 5/196:15 am
BUF
- OMA
1 stop7h 05m
Delta
Deal found 4/21![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/135:07 pm
OMA
- BUF
1 stop5h 43m
American Airlines
Di 5/197:00 am
BUF
- OMA
2 stops9h 33m
American Airlines
Deal found 4/21![American Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/275:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Sa 5/306:25 am
BUF
- OMA
1 stop4h 20m
Delta
Deal found 4/23![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/194:19 pm
OMA
- BUF
1 stop5h 21m
American Airlines
Di 5/264:15 pm
BUF
- OMA
2 stops8h 44m
American Airlines
Deal found 4/21![American Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 6/66:36 pm
CID
- BUF
1 stop4h 31m
American Airlines
Mi 6/108:00 am
BUF
- CID
1 stop5h 56m
American Airlines
Deal found 4/18![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/285:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Do 6/46:25 am
BUF
- OMA
1 stop4h 20m
Delta
Deal found 4/23![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/2810:00 am
CID
- BUF
1 stop5h 46m
United Airlines
Mo 6/15:52 pm
BUF
- CID
1 stop4h 39m
United Airlines
Deal found 4/19![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/286:38 pm
CID
- BUF
1 stop4h 31m
American Airlines
Mo 6/14:15 pm
BUF
- CID
2 stops8h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 6/186:56 pm
MLI
- BUF
1 stop4h 11m
American Airlines
So 6/216:00 am
BUF
- MLI
1 stop5h 26m
American Airlines
Deal found 4/20![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/2911:43 am
CID
- BUF
2 stops9h 07m
American Airlines
Mo 6/14:15 pm
BUF
- CID
2 stops8h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/157:05 am
OMA
- BUF
1 stop7h 45m
Delta
Mi 5/203:52 pm
BUF
- OMA
1 stop5h 59m
Delta
Deal found 4/21![Delta logo]()
$332
Best flights from Iowa to BuffaloDiscover carefully curated flight deals from Iowa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Iowa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/136:30 am
OMA
- BUF
1 stop6h 37m
Delta
Di 5/196:15 am
BUF
- OMA
1 stop7h 05m
Delta
Deal found 4/21![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/2911:28 am
CID
- BUF
1 stop4h 18m
United Airlines
Mo 6/15:52 pm
BUF
- CID
1 stop7h 23m
United Airlines
Deal found 4/19![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/36:47 pm
CID
- BUF
1 stop3h 57m
American Airlines
Do 7/96:00 am
BUF
- CID
1 stop6h 10m
American Airlines
Deal found 4/21![American Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/151:10 pm
OMA
- BUF
2 stops8h 30m
Southwest
Sa 8/156:05 am
BUF
- OMA
1 stop13h 00m
Southwest
Deal found 4/20![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/66:30 am
CID
- BUF
1 stop5h 48m
United Airlines
So 5/105:55 pm
BUF
- CID
1 stop4h 43m
United Airlines
Deal found 4/21![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/2511:00 am
MLI
- BUF
2 stops11h 03m
Delta
Sa 10/39:00 am
BUF
- MLI
2 stops8h 22m
Delta
Deal found 4/20![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 8/111:09 am
MLI
- BUF
2 stops9h 55m
American Airlines
Do 8/66:30 am
BUF
- MLI
1 stop5h 33m
American Airlines
Deal found 4/21![American Airlines logo]()
$352
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/911:23 am
DSM
- BUF
1 stop4h 23m
United Airlines
Mi 6/105:52 pm
BUF
- DSM
1 stop4h 48m
United Airlines
Deal found 4/21![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/155:40 am
LSE
- BUF
1 stop4h 11m
American Airlines
Mo 5/186:00 am
BUF
- LSE
1 stop4h 24m
American Airlines
Deal found 4/20![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/255:35 am
OMA
- BUF
1 stop4h 10m
Southwest
So 9/276:20 am
BUF
- OMA
2 stops9h 10m
Southwest
Deal found 4/22![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/295:12 pm
OMA
- BUF
1 stop5h 20m
Delta
So 5/316:25 am
BUF
- OMA
1 stop4h 15m
Delta
Deal found 4/22![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/2211:28 am
CID
- BUF
1 stop4h 18m
United Airlines
Mo 5/255:57 pm
BUF
- CID
1 stop4h 39m
United Airlines
Deal found 4/18![United Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 6/126:37 pm
CID
- BUF
1 stop4h 30m
American Airlines
Sa 6/206:00 am
BUF
- CID
1 stop6h 12m
American Airlines
Deal found 4/18![American Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/1011:08 am
MLI
- BUF
2 stops11h 50m
Delta
Mi 7/156:07 am
BUF
- MLI
2 stops11h 18m
Delta
Deal found 4/21![Delta logo]()
$404
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 6/264:40 pm
DSM
- BUF
2 stops6h 30m
Southwest
Di 6/304:25 pm
BUF
- DSM
2 stops7h 20m
Southwest
Deal found 4/21![Southwest logo]()
$451
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 6/61:05 pm
DSM
- BUF
1 stop6h 58m
United Airlines
Di 6/97:00 am
BUF
- DSM
1 stop4h 27m
United Airlines
Deal found 4/22![United Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 6/186:56 pm
MLI
- BUF
1 stop4h 11m
American Airlines
So 6/216:00 am
BUF
- MLI
1 stop5h 26m
American Airlines
Deal found 4/23![American Airlines logo]()
$390
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 7/44:09 pm
OMA
- BUF
1 stop5h 48m
Delta
Do 7/166:07 am
BUF
- OMA
1 stop4h 36m
Delta
Deal found 4/20![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 8/292:34 pm
CID
- BUF
1 stop5h 34m
United Airlines
Mi 9/25:52 pm
BUF
- CID
1 stop4h 37m
United Airlines
Deal found 4/18![United Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 8/16:47 pm
CID
- BUF
1 stop4h 20m
American Airlines
Sa 8/86:30 am
BUF
- CID
1 stop4h 57m
American Airlines
Deal found 4/21![American Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 6/225:10 am
DSM
- BUF
2 stops9h 15m
Southwest
Di 6/304:25 pm
BUF
- DSM
2 stops7h 20m
Southwest
Deal found 4/22![Southwest logo]()
$492
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/16:25 am
OMA
- BUF
1 stop3h 59m
Delta
Mi 7/86:07 am
BUF
- OMA
1 stop4h 36m
Delta
Deal found 4/22![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/1011:23 am
DSM
- BUF
1 stop4h 23m
United Airlines
Mi 7/157:00 am
BUF
- DSM
1 stop4h 27m
United Airlines
Deal found 4/21![United Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 8/216:34 pm
MLI
- BUF
1 stop4h 06m
American Airlines
Fr 8/284:18 pm
BUF
- MLI
2 stops8h 05m
American Airlines
Deal found 4/21![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/175:54 pm
OMA
- BUF
1 stop5h 08m
Delta
So 6/216:07 am
BUF
- OMA
1 stop4h 36m
Delta
Deal found 4/23![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/292:34 pm
CID
- BUF
1 stop5h 07m
United Airlines
Mo 8/35:52 pm
BUF
- CID
1 stop4h 49m
United Airlines
Deal found 4/18![United Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 6/51:37 pm
DSM
- BUF
1 stop7h 59m
American Airlines
Fr 6/128:00 am
BUF
- DSM
1 stop6h 20m
American Airlines
Deal found 4/18![American Airlines logo]()
$415
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/246:25 am
OMA
- BUF
1 stop3h 58m
Delta
Mo 7/276:07 am
BUF
- OMA
1 stop4h 36m
Delta
Deal found 4/18![Delta logo]()
$423
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 8/293:44 pm
MLI
- BUF
1 stop4h 24m
United Airlines
Di 9/17:00 am
BUF
- MLI
1 stop6h 58m
United Airlines
Deal found 4/20![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 6/221:37 pm
DSM
- BUF
1 stop7h 59m
American Airlines
Di 6/306:02 am
BUF
- DSM
2 stops8h 18m
American Airlines
Deal found 4/22![American Airlines logo]()
$424
Last-minute flights from Iowa to BuffaloDiscover last-minute flight deals from Iowa to Buffalo. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Buffalo. Data last updated April 23, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/66:30 am
CID
- BUF
1 stop5h 48m
United Airlines
So 5/105:55 pm
BUF
- CID
1 stop4h 43m
United Airlines
Deal found 4/21![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/136:30 am
OMA
- BUF
1 stop6h 37m
Delta
Di 5/196:15 am
BUF
- OMA
1 stop7h 05m
Delta
Deal found 4/21![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/135:07 pm
OMA
- BUF
1 stop5h 43m
American Airlines
Di 5/197:00 am
BUF
- OMA
2 stops9h 33m
American Airlines
Deal found 4/21![American Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/157:05 am
OMA
- BUF
1 stop7h 45m
Delta
Mi 5/203:52 pm
BUF
- OMA
1 stop5h 59m
Delta
Deal found 4/21![Delta logo]()
$332
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/152:50 pm
OMA
- BUF
1 stop8h 00m
American Airlines
Mi 5/207:25 am
BUF
- OMA
2 stops9h 56m
American Airlines
Deal found 4/21![American Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/195:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Di 5/266:25 am
BUF
- OMA
1 stop4h 20m
Delta
Deal found 4/21![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/194:19 pm
OMA
- BUF
1 stop5h 21m
American Airlines
Di 5/264:15 pm
BUF
- OMA
2 stops8h 44m
American Airlines
Deal found 4/21![American Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/275:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Sa 5/306:25 am
BUF
- OMA
1 stop4h 20m
Delta
Deal found 4/23![Delta logo]()
$290
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/285:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Do 6/46:25 am
BUF
- OMA
1 stop4h 20m
Delta
Deal found 4/23![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/2810:00 am
CID
- BUF
1 stop5h 46m
United Airlines
Mo 6/15:52 pm
BUF
- CID
1 stop4h 39m
United Airlines
Deal found 4/19![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/286:38 pm
CID
- BUF
1 stop4h 31m
American Airlines
Mo 6/14:15 pm
BUF
- CID
2 stops8h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/2911:43 am
CID
- BUF
2 stops9h 07m
American Airlines
Mo 6/14:15 pm
BUF
- CID
2 stops8h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$330
One-way flights from Iowa to BuffaloSearch for one-way flight options from Iowa to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Iowa to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/268:19 pm
OMA
- BUF
2 stops16h 35m
Frontier
Deal found 4/23![Frontier logo]()
$131
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/275:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Deal found 4/23![Delta logo]()
$132
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/285:12 pm
OMA
- BUF
1 stop5h 20m
Delta
Deal found 4/23![Delta logo]()
$159
This Trip.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 6/78:19 pm
OMA
- BUF
2 stops16h 35m
Frontier
Deal found 4/21![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/278:19 pm
OMA
- BUF
2 stops22h 45m
Frontier
Deal found 4/23![Frontier logo]()
$178
This Trip.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 5/38:58 pm
OMA
- BUF
2 stops13h 49m
Frontier
Deal found 4/20![Frontier logo]()
$190
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/271:49 pm
OMA
- BUF
1 stop7h 47m
American Airlines
Deal found 4/23![American Airlines logo]()
$196
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/2612:35 pm
OMA
- BUF
1 stop9h 57m
Delta
Deal found 4/23![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/213:56 pm
DSM
- BUF
1 stop7h 00m
American Airlines
Deal found 4/21![American Airlines logo]()
$204
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/171:49 pm
OMA
- BUF
1 stop8h 00m
American Airlines
Deal found 4/20![American Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 8/66:00 am
OMA
- BUF
2 stops7h 25m
United Airlines
Deal found 4/20![United Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/288:19 pm
OMA
- BUF
2 stops16h 35m
Frontier
Deal found 4/23![Frontier logo]()
$213
Find flight deals from Iowa to Buffalo
Keep the following information in mind while searching for Iowa to Buffalo flight deals. Data was last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (Delta) |
One-way from | $161 (Trip.com) |
Popular in | March |
Cheapest in | June |
Average price | $364 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Iowa to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaBuffalo
OMA - BUF
OMABUF
Omaha Eppley Airfield
Mi 5/13
6:30 am-2:07 pm
1 stop6h 37m
Buffalo
Di 5/19
6:15 am-12:20 pm
1 stop7h 05m
$275
Cedar RapidsBuffalo
CID - BUF
CIDBUF
Cedar Rapids
Fr 5/29
11:28 am-4:46 pm
1 stop4h 18m
Buffalo
Mo 6/1
5:52 pm-12:15 am
1 stop7h 23m
$320
Cedar RapidsBuffalo
CID - BUF
CIDBUF
Cedar Rapids
Fr 7/3
6:47 pm-11:44 pm
1 stop3h 57m
Buffalo
Do 7/9
6:00 am-11:10 am
1 stop6h 10m
$320
Cedar RapidsBuffalo
CID - BUF
CIDBUF
Cedar Rapids
Mi 5/6
6:30 am-1:18 pm
1 stop5h 48m
Buffalo
So 5/10
5:55 pm-9:38 pm
1 stop4h 43m
$339
MolineBuffalo
MLI - BUF
MLIBUF
Moline Quad-City
Fr 9/25
11:00 am-11:03 pm
2 stops11h 03m
Buffalo
Sa 10/3
9:00 am-4:22 pm
2 stops8h 22m
$339
Des MoinesBuffalo
DSM - BUF
DSMBUF
Des Moines
Di 6/9
11:23 am-4:46 pm
1 stop4h 23m
Buffalo
Mi 6/10
5:52 pm-9:40 pm
1 stop4h 48m
$349
MolineBuffalo
MLI - BUF
MLIBUF
Moline Quad-City
Sa 8/1
11:09 am-10:04 pm
2 stops9h 55m
Buffalo
Do 8/6
6:30 am-11:03 am
1 stop5h 33m
$352
Cedar RapidsBuffalo
CID - BUF
CIDBUF
Cedar Rapids
Fr 5/22
11:28 am-4:46 pm
1 stop4h 18m
Buffalo
Mo 5/25
5:57 pm-9:36 pm
1 stop4h 39m
$356
La CrosseBuffalo
LSE - BUF
LSEBUF
La Crosse
Fr 5/15
5:40 am-10:51 am
1 stop4h 11m
Buffalo
Mo 5/18
6:00 am-9:24 am
1 stop4h 24m
$363
Cedar RapidsBuffalo
CID - BUF
CIDBUF
Cedar Rapids
Fr 6/12
6:37 pm-12:07 am
1 stop4h 30m
Buffalo
Sa 6/20
6:00 am-11:12 am
1 stop6h 12m
$365
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Iowa to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Iowa with our price prediction graph.
OMA-BUF
CID-BUF
MLI-BUF
DSM-BUF
LSE-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Buffalo
USIA-BUF
OMA-BUF
CID-BUF
MLI-BUF
DSM-BUF
What is the cheapest month to book a flight from Iowa to Buffalo?
Currently, June is the cheapest month in which you can book a flight from Iowa to Buffalo (average of $100). Flying from Iowa to Buffalo in March is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Buffalo?
Related info for your journey
Find useful and relevant information for your journey from Iowa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Iowa to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Buffalo by cabin class
Find flights from Iowa to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Buffalo flights
Browse other Iowa and Buffalo flight options. Last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Buffalo flights
Consider these flights traveling from Iowa to Buffalo.
Top 3 airlines flying from Iowa to Buffalo
Discover the top 3 airlines that operate flights from Iowa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$332 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$225 | Average$444 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$238 | Average$326 | FlexibilityNo cancel fee | On-time71% |