$232+ Cheap flights from Iowa to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BUF
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Buffalo
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Cheapest flights from Iowa to BuffaloExplore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:28 am -
1 stop4h 07m
Tue 10/136:15 am -
1 stop4h 35m
Deal found 9/14![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:13 pm -
1 stop4h 34m
Tue 10/610:46 am -
1 stop4h 31m
Deal found 9/10![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:08 pm -
1 stop6h 51m
Tue 10/135:57 pm -
2 stops7h 34m
Deal found 9/14![American Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:45 am -
2 stops9h 11m
Tue 10/207:00 am -
2 stops9h 38m
Deal found 9/10![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:13 pm -
1 stop4h 34m
Tue 10/67:00 am -
1 stop4h 25m
Deal found 9/10![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:03 pm -
1 stop5h 44m
Tue 10/65:57 pm -
2 stops7h 34m
Deal found 9/10![American Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
1 stop5h 41m
Tue 10/207:00 am -
1 stop6h 45m
Deal found 9/14![American Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:50 pm -
1 stop4h 09m
Tue 10/135:50 pm -
1 stop7h 09m
Deal found 9/11![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:20 am -
1 stop5h 45m
Sun 12/68:00 am -
1 stop3h 50m
Deal found 9/13![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:59 pm -
1 stop6h 47m
Fri 11/274:18 pm -
2 stops8h 36m
Deal found 9/14![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:39 am -
1 stop7h 11m
Mon 11/96:46 pm -
1 stop6h 46m
Deal found 9/10![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:48 pm -
1 stop7h 45m
Wed 11/116:30 am -
1 stop4h 53m
Deal found 9/14![United Airlines logo]()
$349
Best flights from Iowa to BuffaloDiscover carefully curated flight deals from Iowa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Iowa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:28 am -
1 stop4h 07m
Tue 10/206:15 am -
1 stop4h 35m
Deal found 9/10![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:45 am -
2 stops9h 11m
Tue 10/207:00 am -
2 stops9h 38m
Deal found 9/10![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:13 pm -
1 stop4h 34m
Tue 10/67:00 am -
1 stop4h 25m
Deal found 9/10![United Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:00 pm -
1 stop6h 52m
Tue 10/610:00 am -
1 stop7h 14m
Deal found 9/10![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:50 pm -
1 stop4h 09m
Tue 10/135:50 pm -
1 stop7h 09m
Deal found 9/11![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:48 pm -
1 stop7h 45m
Wed 11/116:30 am -
1 stop4h 53m
Deal found 9/14![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:20 am -
2 stops9h 50m
Sun 12/68:00 am -
1 stop3h 50m
Deal found 9/13![American Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/303:25 pm -
1 stop4h 27m
Wed 2/36:30 am -
1 stop6h 57m
Deal found 9/14![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:28 pm -
1 stop5h 19m
Sun 10/187:00 am -
1 stop4h 12m
Deal found 9/11![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:50 pm -
1 stop4h 09m
Sun 10/258:00 am -
1 stop4h 53m
Deal found 9/13![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:50 pm -
1 stop5h 09m
Sun 10/186:15 am -
1 stop4h 27m
Deal found 9/14![Delta logo]()
$412
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:15 pm -
1 stop4h 54m
Fri 10/165:57 pm -
2 stops7h 17m
Deal found 9/10![American Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/309:03 am -
2 stops12h 58m
Wed 2/32:44 pm -
2 stops9h 58m
Deal found 9/10![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:50 pm -
1 stop6h 28m
Tue 10/67:00 am -
1 stop7h 14m
Deal found 9/11![American Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:32 pm -
1 stop4h 17m
Wed 10/285:58 pm -
1 stop5h 58m
Deal found 9/10![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:49 am -
1 stop4h 54m
Wed 10/286:30 am -
1 stop4h 14m
Deal found 9/10![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:59 pm -
1 stop6h 47m
Fri 11/278:25 am -
1 stop5h 06m
Deal found 9/14![American Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/112:28 pm -
1 stop5h 19m
Sun 10/187:00 am -
1 stop4h 12m
Deal found 9/13![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:49 am -
1 stop4h 54m
Sat 10/177:00 am -
1 stop4h 12m
Deal found 9/12![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:07 am -
2 stops10h 49m
Sat 10/175:50 pm -
1 stop7h 01m
Deal found 9/12![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:39 pm -
2 stops7h 20m
Tue 10/135:50 pm -
1 stop7h 01m
Deal found 9/14![American Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:58 pm -
2 stops13h 37m
Sun 10/45:45 pm -
1 stop25h 08m
Deal found 9/14![United Airlines logo]()
$661
Last-minute flights from Iowa to BuffaloDiscover last-minute flight deals from Iowa to Buffalo. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Buffalo. Data last updated September 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:13 pm -
1 stop4h 34m
Tue 10/67:00 am -
1 stop4h 25m
Deal found 9/10![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:03 pm -
1 stop5h 44m
Tue 10/65:57 pm -
2 stops7h 34m
Deal found 9/10![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:13 pm -
1 stop4h 34m
Tue 10/610:46 am -
1 stop4h 31m
Deal found 9/10![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:50 pm -
1 stop6h 28m
Tue 10/67:00 am -
1 stop7h 14m
Deal found 9/11![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:50 pm -
1 stop4h 09m
Tue 10/135:50 pm -
1 stop7h 09m
Deal found 9/11![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:28 am -
1 stop4h 07m
Tue 10/136:15 am -
1 stop4h 35m
Deal found 9/14![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:08 pm -
1 stop6h 51m
Tue 10/135:57 pm -
2 stops7h 34m
Deal found 9/14![American Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:15 pm -
1 stop4h 54m
Fri 10/165:57 pm -
2 stops7h 17m
Deal found 9/10![American Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:05 am -
1 stop5h 41m
Tue 10/207:00 am -
1 stop6h 45m
Deal found 9/14![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:28 pm -
1 stop5h 19m
Sun 10/187:00 am -
1 stop4h 12m
Deal found 9/11![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:45 am -
2 stops9h 11m
Tue 10/207:00 am -
2 stops9h 38m
Deal found 9/10![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:50 pm -
1 stop4h 09m
Sun 10/258:00 am -
1 stop4h 53m
Deal found 9/13![American Airlines logo]()
$362
One-way flights from Iowa to BuffaloSearch for one-way flight options from Iowa to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Iowa to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:01 pm -
2 stops15h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$232
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:26 am -
1 stop3h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$259
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:20 pm -
2 stops7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:02 am -
3 stops49h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:13 pm -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:46 am -
1 stop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:32 pm -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:44 pm -
2 stops22h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:15 am -
1 stop4h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:59 am -
1 stop6h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Delta logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:33 am -
2 stops8h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:42 am -
1 stop5h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$423
Find flight deals from Iowa to Buffalo
Keep the following information in mind while searching for Iowa to Buffalo flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (Delta) |
One-way from | $232 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $388 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Iowa to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Sat 10/3
10:26 am-5:18 pm
1 stop5h 52m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$259
Quickest round-trip
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Tue 9/29
6:26 am-11:22 am
1 stop3h 56m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$259
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Sat 10/3
6:00 am-4:43 pm
2 stops9h 43m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$264
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Tue 9/29
12:20 pm-9:10 pm
2 stops7h 50m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$264
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Sat 10/3
10:02 am-12:55 pm
3 stops49h 53m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Sat 10/17
6:28 am-11:35 am
1 stop4h 07m
Buffalo
Tue 10/20
6:15 am-9:50 am
1 stop4h 35m
$279
OmahaBuffalo
OMA Omaha Eppley Airfield - BUF Buffalo
OMABUF
Omaha Eppley Airfield
Sat 10/3
4:00 pm-11:52 pm
1 stop6h 52m
Buffalo
Tue 10/6
10:00 am-4:14 pm
1 stop7h 14m
$279
Cedar RapidsBuffalo
CID Cedar Rapids - BUF Buffalo
CIDBUF
Cedar Rapids
Fri 10/9
6:13 pm-11:59 pm
1 stop4h 46m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
MolineBuffalo
MLI Moline Quad-City - BUF Buffalo
MLIBUF
Moline Quad-City
Tue 11/24
5:46 am-10:47 am
1 stop4h 01m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Cedar RapidsBuffalo
CID Cedar Rapids - BUF Buffalo
CIDBUF
Cedar Rapids
Fri 10/9
8:01 pm-11:58 am
3 stops38h 57m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$288
Showing 1-10 of 38 resultsSorted by cheapest first
Best time to book a flight from Iowa to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Iowa with our price prediction graph.
OMA-BUF
DSM-BUF
LSE-BUF
MLI-BUF
CID-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Buffalo
USIA-BUF
OMA-BUF
DSM-BUF
LSE-BUF
MLI-BUF
What is the cheapest month to book a flight from Iowa to Buffalo?
Currently, November is the cheapest month in which you can book a flight from Iowa to Buffalo (average of $248). Flying from Iowa to Buffalo in March is currently the most expensive (average of $772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Buffalo?
Airfare is typical for this route at the moment.
Iowa to Buffalo flights typically cost between $317 and $441 in October.The cheapest round-trip price found within the last 5 days was $338 on American Airlines (Oct 14-Oct 20).
Related info for your journey
Find useful and relevant information for your journey from Iowa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes
Buffalo flight routes
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Alternative routes for Iowa to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Buffalo by cabin class
Find flights from Iowa to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Buffalo flights
Browse other Iowa and Buffalo flight options. Last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Buffalo flights
Consider these flights traveling from Iowa to Buffalo.
Top 3 airlines flying from Iowa to Buffalo
Discover the top 3 airlines that operate flights from Iowa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$393 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$548 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$398 | FlexibilityNo cancel fee | On-time69% |