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$181+ Cheap flights from South Padre Island, TX to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — IND
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from South Padre Island to Indianapolis

Cheapest flights from South Padre Island to Indianapolis
Explore the most affordable flight options available from South Padre Island to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:35 am
BRO
-
IND
1 stop28h 42m
Multiple Airlines
Sun 5/313:12 pm
IND
-
BRO
1 stop17h 43m
Multiple Airlines
Deal found 2/2$369
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:50 pm
BRO
-
IND
1 stop5h 22m
American Airlines
Wed 5/136:00 am
IND
-
BRO
1 stop5h 14m
American Airlines
Deal found 2/4$420
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:15 pm
BRO
-
IND
2 stops10h 29m
United Airlines
Sat 2/285:08 pm
IND
-
BRO
1 stop5h 23m
United Airlines
Deal found 2/1$459
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:41 pm
BRO
-
IND
1 stop4h 50m
American Airlines
Sat 6/278:14 pm
IND
-
BRO
1 stop5h 00m
American Airlines
Deal found 2/1$468

Find flight deals from South Padre Island to Indianapolis

Keep the following information in mind while searching for South Padre Island to Indianapolis flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(Kiwi.com)

One-way from

$181
(United Airlines)

Popular in

September

Cheapest in

December

Average price

$434
Provider with most accurate pricing for Brownsville South Padre Is. Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Brownsville South Padre Is. Intl-Indianapolis flights.
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From South Padre Island to Indianapolis
Search Deals
One-way flight from South Padre Island to Indianapolis
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Padre Island to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from South Padre Island to Indianapolis that are best for you.

Fly from

South Padre Island

Fly to

Indianapolis

Route

Depart

Return

Price

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Fri 5/22

8:35 am-2:17 pm

1 stop28h 42m

Indianapolis

Sun 5/31

3:12 pm-7:55 am

1 stop17h 43m

$369

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Wed 5/6

2:50 pm-9:12 pm

1 stop5h 22m

Indianapolis

Wed 5/13

6:00 am-10:14 am

1 stop5h 14m

$420

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Tue 2/24

12:15 pm-11:44 pm

2 stops10h 29m

Indianapolis

Sat 2/28

5:08 pm-9:31 pm

1 stop5h 23m

$459

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Sun 6/21

6:41 pm-12:31 am

1 stop4h 50m

Indianapolis

Sat 6/27

8:14 pm-12:14 am

1 stop5h 00m

$468

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Mon 4/20

5:25 pm-11:19 pm

1 stop4h 54m

$181

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Sun 5/10

7:20 am-4:47 pm

2 stops8h 27m

$352

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Sun 2/22

7:18 am-4:49 pm

2 stops8h 31m

$353

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Sun 5/10

10:44 am-6:05 pm

1 stop6h 21m

$447

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Best time to book a flight from South Padre Island to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Padre Island with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Padre Island to Indianapolis

What is the cheapest month to book a flight from South Padre Island to Indianapolis?

Currently, July is the cheapest month in which you can book a flight from South Padre Island to Indianapolis (average of $149). Flying from South Padre Island to Indianapolis in August is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Padre Island to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated February 4, 2026.
Get a feel of what it's like to fly with American Airlines from South Padre Island to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,222 reviews

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
11,222 reviews
American Airlines
7.2
Good
11,222 reviews

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from South Padre Island to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Padre Island?

    Most people fly into Indianapolis (IND) if they book a flight to Indianapolis from South Padre Island. On average, Indianapolis has 0 inbound flights from South Padre Island per day from 2 airlines. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How long is the flight from South Padre Island to Indianapolis?

    For as low as $420, American Airlines can have you in Indianapolis from South Padre Island in 5h 22m. There are 1149 mi between South Padre Island and Indianapolis. This flight may include one or multiple stops.

  • Can I find deals for flights from South Padre Island to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Padre Island to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Padre Island to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Padre Island to Indianapolis.

  • Can I find deals for business class flights from South Padre Island to Indianapolis?

    Yes. Cheapflights offers flight deals from South Padre Island to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Padre Island to Indianapolis?

    Currently, July is the cheapest month in which you can book a flight from South Padre Island to Indianapolis (average of $149). Flying from South Padre Island to Indianapolis in August is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

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Alternative routes for South Padre Island to Indianapolis

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Top 2 airlines flying from South Padre Island to Indianapolis

Discover the top 2 airlines that operate flights from South Padre Island to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$276FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$224Average$419FlexibilityNo cancel feeOn-time71%

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