HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$65+ Cheap flights from Key Largo, FL to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — IND
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Key Largo to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Key Largo to Indianapolis are usually found in August or January, booked 52 days in advance, depart on a Wednesday or Thursday and return on a Friday

Cheap flight deals from Key Largo to Indianapolis

Keep the following information in mind while searching for Key Largo to Indianapolis flight deals. Data was last updated September 15, 2025.

Round-trip from

$131
(American Airlines)

One-way from

$65
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$291
From Key Largo to Indianapolis
Search Deals
One-way flight from Key Largo to Indianapolis
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Key Largo to Indianapolis

Cheapest flights from Key Largo to Indianapolis
Explore the most affordable flight options available from Key Largo to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/239:41 pmMIA - IND
Nonstop2h 54mAmerican Airlines
Sun 10/267:07 pmIND - MIA
Nonstop2h 45mAmerican Airlines
Deal found 9/14$131
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:00 amMIA - IND
Nonstop2h 57mAmerican Airlines
Mon 11/247:12 pmIND - MIA
Nonstop2h 48mAmerican Airlines
Deal found 9/14$134
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:15 amMIA - IND
1 stop5h 21mFrontier
Mon 10/273:34 pmIND - MIA
1 stop9h 16mFrontier
Deal found 9/14$143
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:42 amMIA - IND
1 stop10h 29mFrontier
Thu 10/168:51 pmIND - MIA
1 stop9h 28mFrontier
Deal found 9/13$144
This Booking.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:00 amMIA - IND
1 stop14h 04mFrontier
Fri 10/38:58 pmIND - MIA
1 stop27h 46mFrontier
Deal found 9/13$145
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:42 amMIA - IND
1 stop10h 29mFrontier
Mon 10/1311:31 amIND - MIA
1 stop13h 03mFrontier
Deal found 9/13$153
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:30 amMIA - IND
1 stop5h 41mMultiple Airlines
Wed 10/111:55 amIND - MIA
1 stop6h 18mMultiple Airlines
Deal found 9/15$155
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:30 pmMIA - IND
Nonstop2h 47mAmerican Airlines
Sat 11/17:07 pmIND - MIA
Nonstop2h 45mAmerican Airlines
Deal found 9/13$159
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1610:42 amMIA - IND
1 stop25h 18mFrontier
Sun 10/198:51 pmIND - MIA
1 stop9h 28mFrontier
Deal found 9/14$162
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:30 amMIA - IND
1 stop5h 41mFrontier
Thu 10/99:54 amIND - MIA
1 stop6h 09mFrontier
Deal found 9/13$170
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:30 pmMIA - IND
1 stop4h 25mSouthwest
Tue 10/215:50 amIND - MIA
1 stop6h 25mSouthwest
Deal found 9/14$179
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amMIA - IND
1 stop13h 44mFrontier
Sun 11/28:39 pmIND - MIA
1 stop9h 40mFrontier
Deal found 9/15$180

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Key Largo to Indianapolis that are best for you.

Fly from

Key Largo

Fly to

Indianapolis

Route

Depart

Return

Price

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Thu 10/9

10:42 am-9:11 pm

1 stop10h 29m

Indianapolis

Thu 10/16

8:51 pm-6:19 am

1 stop9h 28m

$144

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Fri 10/24

5:15 am-10:36 am

1 stop5h 21m

Indianapolis

Sun 10/26

9:54 am-4:03 pm

1 stop6h 09m

$144

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Fri 9/26

5:30 am-11:11 am

1 stop5h 41m

Indianapolis

Wed 10/1

11:55 am-6:13 pm

1 stop6h 18m

$155

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Tue 10/14

5:30 pm-9:55 pm

1 stop4h 25m

Indianapolis

Tue 10/21

5:50 am-12:15 pm

1 stop6h 25m

$179

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Fri 10/24

5:15 am-10:36 am

1 stop5h 21m

Indianapolis

Mon 10/27

8:51 pm-1:28 pm

2 stops16h 37m

$194

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Wed 10/8

12:09 pm-7:15 pm

1 stop7h 06m

Indianapolis

Tue 10/14

7:00 am-1:11 pm

1 stop6h 11m

$198

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Fri 10/31

5:05 am-11:22 am

1 stop6h 17m

Indianapolis

Sun 11/2

10:04 pm-10:11 am

2 stops12h 07m

$206

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Thu 11/13

6:00 am-7:31 pm

1 stop13h 31m

Indianapolis

Wed 11/19

5:49 am-8:58 pm

2 stops15h 09m

$213

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Fri 9/26

5:30 am-11:11 am

1 stop5h 41m

Indianapolis

Sun 9/28

5:22 pm-9:38 pm

2 stops28h 16m

$213

MiamiIndianapolis

MIA - IND

MIAIND

Miami

Sat 9/27

6:45 am-4:14 pm

1 stop9h 29m

Indianapolis

Sun 9/28

5:22 pm-6:57 pm

2 stops25h 35m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 20 results
1
2

Best time to book a flight from Key Largo to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Indianapolis

How far ahead should I book a flight from Key Largo to Indianapolis?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Indianapolis. Price data was last updated on September 12, 2025.

Booking 52 days in advance of your planned departure date is, on average, the best time to get cheap flights from Key Largo to Indianapolis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Key Largo to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Key Largo to Indianapolis (average of $286). Flying from Key Largo to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to IND?

Find hourly flight availability from Key Largo to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key Largo to Indianapolis as you normally would.

What is the cheapest day to fly from Key Largo to Indianapolis?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Indianapolis. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Key Largo to Indianapolis flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Indianapolis

Explore weekly flight availability from Key Largo to Indianapolis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from KE9 to IND are scheduled on a Saturday (4 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 15, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Key Largo to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Allegiant Air
7.2
Good
699 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,015 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Key Largo?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Key Largo to Indianapolis. You should not have trouble finding flights to Indianapolis from Key Largo; the airport handles an average of 2 inbound flights from Key Largo per day. You should also have plenty of airline options to choose from since 6 airlines have flights to the Indianapolis airport from Key Largo. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Key Largo to Indianapolis?

    Airlines like Frontier and Southwest fly from Key Largo to Indianapolis in about 4h 25m. The time it takes to get you to your destination can typically vary by up to 6h 04m. There are 1022 mi between Key Largo and Indianapolis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to Indianapolis one-way?

    One-way options have recently been found by users for as low as $66 on American Airlines. Other airlines that offer cheap prices include Frontier from $71 and Southwest from $90 one-way.

  • What are the most reliable airlines from Key Largo to Indianapolis?

    The top 3 most reliable airlines when flying from Key Largo to Indianapolis are American Airlines (65%), Qatar Airways (55%) and Envoy Air (50%).

  • What are the cheapest flights from Key Largo to Indianapolis?

    Looking for the cheapest flight from Key Largo to Indianapolis? While on average our users pay $282, our data indicates the cheapest price to be $141. The most popular route (Miami - Indianapolis), is priced around $168.

  • Can I find deals for flights from Key Largo to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Key Largo to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Indianapolis.

  • Can I find deals for business class flights from Key Largo to Indianapolis?

    Yes. Cheapflights offers flight deals from Key Largo to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Key Largo to Indianapolis (average of $286). Flying from Key Largo to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key Largo to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Tampa to O'Hare Intl flights
Miami to O'Hare Intl flights
Orlando to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Jacksonville to O'Hare Intl flights
Orlando to Midway flights
Tampa to Midway flights
West Palm Beach to O'Hare Intl flights
Miami to Midway flights
Fort Myers to O'Hare Intl flights
Jacksonville to Midway flights
Fort Lauderdale to Midway flights
Tampa to Cincinnati flights
Orlando to Cincinnati flights
Pensacola to O'Hare Intl flights
Fort Lauderdale to Indianapolis flights
West Palm Beach to Midway flights
Orlando to Indianapolis flights
Orlando to Louisville flights
Miami to Louisville flights
Fort Lauderdale to Cincinnati flights
Fort Myers to Midway flights
Tampa to Indianapolis flights
Fort Myers to Cincinnati flights
Sarasota to O'Hare Intl flights
Miami to Indianapolis flights
Fort Lauderdale to Louisville flights
Fort Myers to Indianapolis flights
Tampa to Louisville flights
Pensacola to Midway flights
Orlando Sanford Intl to Cincinnati flights
Daytona Beach to O'Hare Intl flights
Melbourne to O'Hare Intl flights
Jacksonville to Indianapolis flights
Tampa to Dayton flights
Miami to Cincinnati flights
St Petersburg to Cincinnati flights
Sarasota to Indianapolis flights
Panama City to O'Hare Intl flights
West Palm Beach to Cincinnati flights
Gainesville to O'Hare Intl flights
Tallahassee to O'Hare Intl flights
Panama City to Midway flights
Sarasota to Midway flights
Orlando Sanford Intl to Indianapolis flights
Orlando to Dayton flights
Valparaiso to O'Hare Intl flights
West Palm Beach to Indianapolis flights
Jacksonville to Louisville flights
Sarasota to Dayton flights

Top 6 airlines flying from Key Largo to Indianapolis

Discover the top 6 airlines that operate flights from Key Largo to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$86Average$169FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$87Average$145FlexibilityNo cancel feeOn-time65%
FrontierCheapest$159Average$224FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$185Average$347FlexibilityNo cancel feeOn-time71%
DeltaCheapest$191Average$320FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$207Average$412FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.